Identification and characterization of nematode specific protective epitopes of Brugia malayi TRX towards development of synthetic vaccine construct for lymphatic filariasis

Vaccine

Volumn 28, Issue 31, 2010, Pages 5038-5048

  Madhumathi, Jayaprakasam ^a   Prince, Prabhu Rajaiah ^a   Anugraha, Gandhirajan ^a   Kiran, Pote ^c   Rao, Donthamsetty Nageswara ^b   Reddy, Maryada Venkata Rami ^c   Kaliraj, Perumal ^a  

^a ANNA UNIVERSITY   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^c MAHATMA GANDHI INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Filariasis; Multi epitope vaccine; Thioredoxin

Indexed keywords

ANTIOXIDANT; CYTOKINE; EPITOPE; GAMMA INTERFERON; IMMUNOGLOBULIN G; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; MULTI EPITOPE VACCINE; SYNTHETIC PEPTIDE; THIOREDOXIN; UNCLASSIFIED DRUG; VACCINE; HELMINTH ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; B LYMPHOCYTE; BRUGIA MALAYI; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FILARIASIS; HUMAN; IMMUNE RESPONSE; IMMUNOGENICITY; LYMPHATIC FILARIASIS; MALE; MOUSE; NEMATODE; NONHUMAN; PEPTIDE SYNTHESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; T LYMPHOCYTE; VACCINE PRODUCTION; ANIMAL; BAGG ALBINO MOUSE; BLOOD; ELEPHANTIASIS, FILARIAL; FEMALE; IMMUNOLOGY; MURINAE;

ANIMALS; ANTIBODIES, HELMINTH; BRUGIA MALAYI; CELL PROLIFERATION; CYTOKINES; ELEPHANTIASIS, FILARIAL; EPITOPES, B-LYMPHOCYTE; EPITOPES, T-LYMPHOCYTE; FEMALE; HUMANS; IMMUNODOMINANT EPITOPES; IMMUNOGLOBULIN G; MALE; MICE; MICE, INBRED BALB C; MURINAE; T-LYMPHOCYTES; THIOREDOXINS; VACCINES, CONJUGATE;

EID: 77954759726     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2010.05.012     Document Type: Article

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