Brugia malayi: Comparison of protective immune responses induced by Bm-alt-2 DNA, recombinant Bm-ALT-2 protein and prime-boost vaccine regimens in a jird model

Experimental Parasitology

Volumn 116, Issue 4, 2007, Pages 483-491

  Thirugnanam, Sivasakthivel ^a   Pandiaraja, Pandurangan ^a   Ramaswamy, Kalyanasundaram ^b   Murugan, Vadivel ^a   Gnanasekar, Munirathinam ^b   Nandakumar, Krithika ^c   Reddy, Maryada Venkata Rami ^c   Kaliraj, Perumal ^a  

^a ANNA UNIVERSITY   (India)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c MAHATMA GANDHI INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

abundant larval transcript 2 gene; Abundant Larval Transcript 2 protein; alt 2; ALT 2; asymptomatic microfilaremic patients; Bm; Bm alt 2; Brugia malayi; chronic pathology patients; CP; DNA prime protein boost vaccination; EN; endemic normal individuals; Filariasis; IFN ; IL; interferon gamma; Interleukin; L2; L3; Larval stage 2; Larval stage 3 (Infective larvae); MF; T helper cells; Th

Indexed keywords

ABUNDANT LARVAL TRANSCRIPT 2 PROTEIN; DNA VACCINE; GAMMA INTERFERON; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INTERLEUKIN 4; INTERLEUKIN 5; RECOMBINANT VACCINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; BRUGIA MALAYI; CONTROLLED STUDY; CYTOKINE RELEASE; FILARIASIS; GERBIL; INTERFERON PRODUCTION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN CELL; VACCINATION; VACCINE PRODUCTION;

ANIMALS; ANTIBODIES, HELMINTH; ANTIGENS, HELMINTH; BRUGIA MALAYI; CYTOKINES; DIFFUSION CHAMBERS, CULTURE; DISEASE MODELS, ANIMAL; DNA, HELMINTH; ELEPHANTIASIS, FILARIAL; GERBILLINAE; HELMINTH PROTEINS; IMMUNITY, CELLULAR; IMMUNIZATION; LYMPHOCYTE ACTIVATION; MALE; RECOMBINANT PROTEINS; TH2 CELLS; VACCINES; VACCINES, DNA; VACCINES, SYNTHETIC;

BRUGIA MALAYI; MERIONES;

EID: 34249899966     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2007.02.017     Document Type: Article

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