Immune responses generated by intramuscular DNA immunization of Brugia malayi transglutaminase (BmTGA) in mice

Parasitology

Volumn 136, Issue 8, 2009, Pages 887-894

  Vanam, Uma ^a   Prabhu, Prince R ^a   Pandey, Vivek ^a   Dakshinamurthy, Gajalakshmi ^b   Venkata Rami Reddy, Maryada ^b   Perumal, Kaliraj ^a  

^a ANNA UNIVERSITY   (India)

^b MAHATMA GANDHI INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Cytokine; DNA vaccine; Filariasis; Micropore chamber; Transglutaminase

Indexed keywords

BRUGIA MALAYI TRANSGLUTAMINASE VACCINE; DNA VACCINE; PLASMID DNA; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; PVAX1 VACCINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; BRUGIA MALAYI; BRUGIAN FILARIASIS; CELL PROLIFERATION; CONTROLLED STUDY; DNA IMMUNIZATION; DRUG DISTRIBUTION; DRUG INHIBITION; DRUG MECHANISM; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOSTIMULATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SPLEEN CELL;

ANIMALS; ANTIBODIES, HELMINTH; ANTIBODY SPECIFICITY; ANTIGENS, HELMINTH; BRUGIA MALAYI; CHO CELLS; CRICETINAE; CRICETULUS; CYTOKINES; FILARIASIS; HELMINTH PROTEINS; INJECTIONS, INTRAMUSCULAR; MICE; MICE, INBRED BALB C; TRANSGLUTAMINASES; VACCINATION; VACCINES, DNA;

BRUGIA MALAYI; MUS;

EID: 67749135250     PISSN: 00311820     EISSN: 14698161     Source Type: Journal    
DOI: 10.1017/S0031182009006143     Document Type: Article

References (26)

1. Abraham, D., Lange, A. M., Yutanawiboonchai, W., Trpis, M., Dickerson, J.W., Swenson, B. and Eberhard, M. L. (1993). Survival and development of larval Onchocerca volvulus in diffusion chambers implanted in primate and rodent hosts. Journal of Parasitology 79, 571-582. (Pubitemid 23249747)
2. Ash, L. R. and Riley, J. M. (1970). Development of subperiodic Brugia malayi in the jird, Meriones unguiculatus, with notes on infections in other rodents. Journal of Parasitology 56, 969-973.
3. Chandrashekar, R., Tsuji, N., Morales, T., Ozols, V. and Mehta, K. (1998). An ERp60-like protein from the filarial parasite Dirofilaria immitis has both transglutaminase and protein disulfide isomerase activity. Proceedings of the National Academy of Sciences, USA 95, 531-536. (Pubitemid 28083777)
4. Chenthamarakshan, V., Reddy, M. V. and Harinath, B. C. (1995). Immunoprophylactic potential of a 120 kDa Brugia malayi adult antigen fraction, BmA-2, in lymphatic filariasis. Parasite Immunology 17, 277-285.
5. Folk, J. E. (1983). Mechanism and basis for specificity of transglutaminase-catalyzed epsilon-(gamma-glutamyl) lysine bond formation. Advances in Enzymology and Related Areas of Molecular Biology 54, 1-56.
6. Gnanasekar, M., Rao, K. V., He, Y. X., Mishra, P. K., Nutman, T. B., Kaliraj, P. and Ramaswamy, K. (2004). Novel phage display-based subtractive screening to identify vaccine candidates of Brugia malayi. Infection and Immunity 72, 4707-4715. (Pubitemid 38989331)
7. Grieve, R. B., Wisnewski, N., Frank, G. R. and Tripp, C. A. (1995). Vaccine research and development for the prevention of filarial nematode infections. Pharmaceutical Biotechnology 6, 737-768.
8. Knox, D. P., Redmond, D. L., Skuce, P. J. and Newlands, G. F. (2001). The contribution of molecular biology to the development of vaccines against nematode and trematode parasites of domestic ruminants. Veterinary Parasitology 101, 311-335.
9. Liu, C., Fan, M., Xu, Q. and Li, Y. (2008). Biodistribution and expression of targeted fusion anti-caries DNA vaccine pGJA-P/VAX in mice. Journal of Gene Medicine 10, 298-305. (Pubitemid 351359642)
10. Lustigman, S., Brotman, B., Huima, T., Castelhano, A. L., Singh, R. N., Mehta, K. and Prince, A. M. (1995).Transglutaminase-catalyzed reaction is important for molting of Onchocerca volvulus third-stage larvae. Antimicrobial Agents and Chemotherapy 39, 1913-1919.
11. Lustigman, S. and McCarter, J. P. (2007). Ivermectin resistance in Onchocerca volvulus : toward a genetic basis. PLoS Neglected Tropical Diseases 1, e76. (Pubitemid 352024659)
12. McCluskie, M. J., Brazolot Millan, C. L., Gramzinski, R. A., Robinson, H. L., Santoro, J. C., Fuller, J. T., Widera, G., Haynes, J. R., Purcell, R. H. and Davis, H. L. (1999). Route and method of delivery of DNA vaccine influence immune responses in mice and non-human primates. Molecular Medicine 5, 287-300. (Pubitemid 29342964)
13. Mehta, K., Chandrashekar, R. and Rao, U. R. (1996). Transglutaminase- catalyzed incorporation of host proteins in Brugia malayi microfilariae. Molecular and Biochemical Parasitology 76, 105-114. (Pubitemid 26124382)
14. Mehta, K., Rao, U. R., Vickery, A. C. and Fesus, L. (1992). Identification of a novel transglutaminase from the filarial parasite Brugia malayi and its role in growth and development. Molecular and Biochemical Parasitology 53, 1-15.
15. Ottesen, E. A. (1985). Efficacy of diethylcarbamazine in eradicating infection with lymphatic-dwelling filariae in humans. Reviews of Infectious Diseases 7, 341-356.
16. Ottesen, E. A. (2000). The global programme to eliminate lymphatic filariasis. Tropical Medicine and International Health 5, 591-594. (Pubitemid 30765049)
17. Ramachandran, S., Kumar, M. P., Rami, R. M., Chinnaiah, H. B., Nutman, T., Kaliraj, P. and McCarthy, J. (2004). The larval specific lymphatic filarial ALT-2: induction of protection using protein or DNA vaccination. Microbiology and Immunology 48, 945-955. (Pubitemid 40040702)
18. Rao, U. R., Mehta, K., Subrahmanyam, D. and Vickery, A. C. (1991). Brugia malayi and Acanthocheilonema viteae: antifilarial activity of transglutaminase inhibitors in vitro. Antimicrobial Agents and Chemotherapy. 35, 2219-2224.
19. Robinson, H. L. and Torres, C. A. (1997). DNA vaccines. Seminars in Immunology 9, 271-283.
20. Sahare, K. N., Anandharaman, V., Meshram, V. G., Meshram, S. U., Gajalakshmi, D., Goswami, K. and Reddy, M. V. R. (2008). In vitro effect of four herbal plants on the motility of Brugia malayi microfilariae. Indian Journal of Medical Research 127, 467-471.
21. Suzuki, T. and Seregeg, I. G. (1979). A mass dissection technique for determining infectivity rate of filariasis vectors. Japan Journal of Experimental Medicine 49, 117-121. (Pubitemid 9188978)
22. Tang, D. C., De Vit, M. and Johnston, S. A. (1992). Genetic immunization is a simple method for eliciting an immune response. Nature, London 356, 152-154.
23. Thirugnanam, S., Pandiaraja, P., Ramaswamy, K., Murugan, V., Gnanasekar, M., Nandakumar, K., Reddy, M. V. and Kaliraj, P. (2007). Brugia malayi: comparison of protective immune responses induced by Bm-alt-2 DNA, recombinant Bm-ALT-2 protein and prime-boost vaccine regimens in a jird model. Experimental Parasitology 116, 483-491. (Pubitemid 46863429)
24. Uma, V., Pandey, V., Prabhu, P. R., Dakshinamurthy, G., Reddy, M. V. R. and Kaliraj, P. (2009). Evaluation of immunoprophylactic efficacy of Brugia malayi transglutaminase(BmTGA) in single and multiple antigen vaccination with BmALT-2 and BmTPX for human lymphatic filariasis. American Journal of Tropical Medicine and Hygiene 80, 319-324.
25. Uma, V., Geetha, M., Murugan, V. and Kaliraj, P. (2006). Isolation and characterization of recombinant Brugian parasitic transglutaminase. Indian Journal of Biotechnology 5, 317-326. (Pubitemid 44351304)
26. World Health Organization (2006). Global programme to eliminate lymphatic filariasis. Weekly Epidemiological Record 22, 221-232.