Interleukin-5 is essential for vaccine-mediated immunity but not innate resistance to a filarial parasite

Infection and Immunity

Volumn 68, Issue 5, 2000, Pages 2513-2517

  Le Goff, Laetitia ^a   Loke, P'ng ^a   Ali, H Fahimeda ^a   Taylor, David W ^b   Allen, Judith E ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 5;

ACTIVE IMMUNIZATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; IMMUNE RESPONSE; INFECTION RESISTANCE; LITOMOSOIDES; MOUSE; NONHUMAN; PRIORITY JOURNAL; VACCINATION;

ANIMALS; FILARIASIS; FILARIOIDEA; IMMUNITY, NATURAL; INTERLEUKIN-5; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; VACCINES;

EID: 0034061485     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.5.2513-2517.2000     Document Type: Article

References (39)

1. Abraham, D., M. L. Eberhard, A. M. Lange, W. Yutanawiboonchai, F. B. Perler, and J. B. Lok. 1992. Identification of surrogate rodent hosts for larval Onchocerca lienalis and induction of protective immunity in a model system. J. Parasitol. 78:447-453.
2. + T cells in controlling larval development. Infect. Immun. 65:2457-2461.
3. Allen, J. E., and R. M. Maizels. 1997. Th1-Th2: reliable paradigm or dangerous dogma? Immunol. Today 18:387-392.
4. Bain, O., S. Wanji, P. N. Vuong, P. Maréchal, L. Le Goff, and G. Petit. 1994. Larval biology of six filariae of the sub-family Onchocercinae in a vertebrate host. Parasite 1:241-254.
5. Bancroft, A. J., R. K. Grencis, K. J. Else, and E. Devaney. 1993. Cytokine production in BALB/c mice immunized with radiation attenuated third stage larvae of the filarial nematode, Brugia pahangi. J. Immunol. 150:1395-1402.
6. Behnke, J. M., C. J. Barnard, and D. Wakelin. 1992. Understanding chronic nematode infections - evolutionary considerations, current hypotheses and the way forward. Int. J. Parasitol. 22:861-907.
7. Coffman, R. L., B. W. P. Seymour, S. Hudak, J. Jackson, and D. Rennick. 1989. Antibody to interleukin-5 inhibits helminth-induced eosinophilia in mice. Science 245:308-310.
8. Dent, L. A., C. M. Daly, G. Mayrhofer, T. Zimmerman, A. Hallett, L. P. Bignold, J. Creaney, and J. C. Parsons. 1999. Interleukin-5 transgenic mice show enhanced resistance to primary infections with Nippostrongylus brasiliensis but not primary infections with Toxocara canis. Infect. Immun. 67:989-993.
9. Diagne, M., G. Petit, P. Liot, J. Cabaret, and O. Bain. 1990. The filaria Litomosoides galizai in mites: microfilarial distribution in the host and regulation of the transmission. Ann. Parasitol. Hum. Comp. 65:193-199.
10. Folkard, S. G., P. J. Hogarth, M. J. Taylor, and A. E. Bianco. 1996. Eosinophils are the major effector cells of immunity to microfilariae in a mouse model of onchocerciasis. Parasitology 112:323-329.
11. Grencis, R. K. 1996. T cell and cytokine basis of host variability in response to intestinal nematode infections. Parasitology 112:S31-S37.
12. Hall, L. R., R. K. Mehlotra, A. W. Higgins, M. A. Haxhiu, and E. Pearlman. 1998. An essential role for interleukin-5 and eosinophils in helminth-induced airway hyperresponsiveness. Infect. Immun. 66:4425-4430.
13. Hogarth, P. J., M. J. Taylor, and A. E. Bianco. 1998. IL-5-dependenr immunity to microfilariae is independent of IL-4 in a mouse model of onchocerciasis. J. Immunol. 160:5436-5440.
14. Johnson, E. H., S. Schynder-Candrian, T. V. Rajan, F. K. Nelson, S. Lustigman, and D. Abraham. 1998. Immune responses to third stage larvae of Onchocerca volvulus in interferon-γ and interleukin-4 knockout mice. Parasite Immunol. 20:319-324.
15. + B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses. Immunity 4:15-24.
16. Korenaga, M., and I. Tada. 1994. The role of IL-5 in the immune responses to nematodes in rodents. Parasitol. Today 10:234-236.
17. Lange, A. M., W. Yutanawiboonchai, P. Scott, and D. Abraham. 1994. IL-4-and IL-5-dependent protective immunity to Onchocerca volvulus infective larvae in BALB/cBYJ mice. J. Immunol. 153:205-211.
18. Lawrence, R. A., J. E. Allen, J. Osborne, and R. M. Maizels. 1994. Adult and microfilarial stages of the filarial parasite Brugia malayi stimulate contrasting cytokine and Ig isotype responses in BALB/c mice. J. Immunol. 153:1216-1224.
19. Le Goff, L., P. Maréchal, G. Petit, D. W. Taylor, W. Hoffman, and O. Bain. 1997. Early reduction of the challenge recovery rate following immunization with irradiated infective larvae in a filaria mouse system. Trop. Med. Int. Health 2:1170-1174.
20. Le Goff, L., C. Martin, I. P. Oswald, P. N. Vuong, G. Petit, M. N. Ungeheuer, and O. Bain. Parasitology and immunology of mice vaccinated with irradiated Litomosoides sigmodontis larvae. Parasitology, in press.
21. Lucius, R., G. Textor, A. Kern, and C. Kirsten. 1991. Acanthocheilonema viteae: vaccination of jirds with irradiation-attenuated stage-3 larvae and with exported larval antigens. Exp. Parasitol. 73:184-196.
22. MacDonald, A. S., P. Loke, and J. E. Allen. Suppressive antigen-presenting cells in helminth infection. Pathobiology, in press.
23. Maréchal, P., L. Le Goff, G. Petit, M. Diagne, D. W. Taylor, and O. Bain. 1996. The fate of the filaria Litomosoides sigmodontis in susceptible and naturally resistant mice. Parasite 3:25-31.
24. Maréchal, P., G. Petit, M. Diagne, D. W. Taylor, and O. Bain. 1994. Use of the Litomosoides sigmodontis-mouse model in development of an Onchocerca vaccine. II. L. sigmodontis in the BALB/c mouse: vaccination experiments; preliminary immunological studies. Parasite 1:31-32.
25. McLeod, R., E. Buschman, L. D. Arbuckle, and E. Skamene. 1995. Immunogenetics in the analysis of resistance to intracellular pathogens. Curr. Opin. Immunol. 7:539-552.
26. Ovington, K. S., K. McKie, K. I. Matthaei, I. G. Young, and C. A. Behm. 1998. Regulation of primary Strongyloides ratti infections in mice: a role for interleukin-5. Immunology 95:488-493.
27. Petit, G., M. Diagne, P. Maréchal, D. Owen, D. Taylor, and O. Bain. 1992. Maturation of the filaria Litomosoides sigmodontis in BALB/c mice; comparative susceptibility of nine other inbred strains. Ann. Parasitol. Hum. Comp. 67:144-150.
28. Purkerson, J. M., and P. C. Isakson. 1992. Interleukin 5 (IL-5) provides a signal that is required in addition to IL-4 for isotype switching to immunoglohulin (Ig) G1 and IgE. J. Exp. Med. 175:973-982.
29. Rajan, T. V., P. Porte, J. A. Yates, L. Keefer, and L. D. Shultz. 1996. Role of nitric oxide in host defense against an extracellular, metazoan parasite, Brugia malayi. Infect. Immun. 64:3351-3353.
30. Reiner, S. L., and R. M. Locksley. 1995. The regulation of immunity to Leishmania major. Annu. Rev. Immunol. 13:151-177.
31. Sartono, E., Y. C. M. Kruize, A. Kurniawan-Atmadja, R. M. Maizels, and M. Yazdanbakhsh. 1996. Depression of antigen-specific interleukin-5 and interferon-γ responses in human lymphatic filariasis as a function of clinical status and age. J. Infect. Dis. 175:1276-1280.
32. Schrempf-Eppstein, B., A. Kern, G. Textor, and R. Lucius. 1997. Acanthocheilonema viteae: vaccination with irradiated L3 induces resistance in three species of rodents (Meriones unguiculatus, Mastomys coucha, Mesocricetus auratus). Trop. Med. Int. Health 2:104-110.
33. Storey, D. M., and A. S. Al-Mukhtar. 1982. Vaccination of jirds, Meriones unguiculatus, against Litonmsoides carinii and Brugia pahangi using irradiated larvae of L carinii. Tropenmed. Parasitol. 33:23-24.
34. Taylor, M. J., R. P. van Es, K. Shay, S. G. Folkard, S. Townson, and A. E. Bianco. 1994. Protective immunity against Onchocerca volvulus and O. lienalis infective larvae in mice. Trop. Med. Parasitol. 45:17-23.
35. Urban, J. F., K. B. Madden, A. Sveti'c, A. Cheever, P. P. Trotta, W. C. Gause, I. M. Katona, and F. D. Finkelman. 1992. The importance of Th2 cytokines in protective immunity to nematodes. Immunol. Rev. 127:205-220.
36. Weil, G. J., B. W. Li, F. Liftis, and R. Chandrashekar. 1992. Brugia malayi -antibody responses to larval antigens in infected and immunized jirds. Exp. Parasitol. 74:315-323.
37. World Health Organization. 1992. Lymphatic filariasis: the disease and its control. Fifth report of the WHO Expert Committee on Filariasis. WHO Tech. Rep. Ser. 821:1-71.
38. 60cobalt-attenuated infective stage larvae protects against homologous challenge. Am. J. Trop. Med. Hyg. 34:1132-1137.
39. Zhang, Y., and E. Y. Denkers. 1999. Protective role for interleukin-5 during chronic Toxoplasma gondii infection. Infect. Immun. 67:4383-4392.