Immunization with inflammatory proteome of Brugia malayi adult worm induces a Th1/Th2-immune response and confers protection against the filarial infection

Vaccine

Volumn 27, Issue 32, 2009, Pages 4263-4271

  Sahoo, M K ^a   Sisodia, B S ^b   Dixit, S ^a   Joseph, S K ^a   Gaur, R L ^a   Verma, S K ^a   Verma, A K ^a   Shasany, A K ^b   Dowle, A A ^c   Murthy, P Kalpana ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b CSIR CENTRAL INSTITUTE OF MEDICINAL AND AROMATIC PLANTS   (India)

^c Proteomics Laboratory   (United Kingdom)

Author keywords

2DE; Brugia malayi; IgG subclasses; Inflammatory cytokines; Lymphoproliferation; MALDI TOF MS; NO

Indexed keywords

ANTINEMATODAL AGENT; CYTOKINE STIMULATING FRACTION F10; CYTOKINE STIMULATING FRACTION F14; CYTOKINE STIMULATING FRACTION F5; CYTOKINE STIMULATING FRACTION F6; ELONGATION FACTOR 2; GAMMA INTERFERON; HEAT SHOCK PROTEIN 60; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B; IMMUNOMODULATING AGENT; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; INTERMEDIATE FILAMENT PROTEIN; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRUGIA MALAYI; BRUGIAN FILARIASIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; IMMUNE RESPONSE; IMMUNITY; IMMUNIZATION; IMMUNOSTIMULATION; LARVA; LYMPHOCYTE PROLIFERATION; MALE; MASTOMYS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; TH1 CELL; TH2 CELL; UPREGULATION; WORM;

ANIMALS; ANTIBODIES, HELMINTH; ANTIGENS, HELMINTH; BRUGIA MALAYI; CYTOKINES; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FILARIASIS; GERBILLINAE; HELMINTH PROTEINS; MALE; MASS SPECTROMETRY; MURINAE; PROTEOME; SURVIVAL ANALYSIS; TH1 CELLS; TH2 CELLS;

EID: 67649513471     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.05.015     Document Type: Article

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