Sterol-regulatory-element-binding protein 2 and nuclear factor Y control human farnesyl diphosphate synthase expression and affect cell proliferation in hepatoblastoma cells

Biochemical Journal

Volumn 429, Issue 2, 2010, Pages 347-357

  Ishimoto, Kenji ^a,b   Tachibana, Keisuke ^a   Hanano, Ikuko ^a   Yamasaki, Daisuke ^a   Nakamura, Hiroki ^a   Kawai, Megumi ^a   Urano, Yasuomi ^c   Tanaka, Toshiya ^c   Hamakubo, Takao ^c   Sakai, Juro ^c   Kodama, Tatsuhiko ^c   Doi, Takefumi ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Cell proliferation; Farnesyl diphosphate synthase (FDPS); Nuclear factor Y(NF Y); Promoter; Sterol regulatory element binding protein (SREBP); Zoledronic acid

Indexed keywords

ELEMENT-BINDING PROTEINS; FARNESYL DIPHOSPHATE SYNTHASE; NUCLEAR FACTORS; STEROL-REGULATORY-ELEMENT-BINDING PROTEIN (SREBP); ZOLEDRONIC ACID;

ACIDS; ALCOHOLS; BINDING ENERGY; CELL PROLIFERATION; ELECTROPHORETIC MOBILITY; LAWS AND LEGISLATION; PROTEINS; TRANSCRIPTION;

FREQUENCY DOMAIN ANALYSIS;

GERANYLTRANSFERASE; LUCIFERASE; NUCLEAR FACTOR Y; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; ZOLEDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; BONE DENSITY CONSERVATION AGENT; CCAAT BINDING FACTOR; DNA; IMIDAZOLE DERIVATIVE; PRIMER DNA; SMALL INTERFERING RNA; SREBF2 PROTEIN, HUMAN; STEROL;

ARTICLE; BINDING SITE; CANCER CELL; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DRUG EFFECT; ELECTROPHORETIC MOBILITY; ENZYME ASSAY; GENETIC TRANSCRIPTION; HEPATOBLASTOMA; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; BIOSYNTHESIS; DRUG ANTAGONISM; GENE SILENCING; GENETIC TRANSFECTION; GENETICS; LIVER TUMOR; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PATHOLOGY; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; TUMOR CELL LINE;

BASE SEQUENCE; BINDING SITES; BONE DENSITY CONSERVATION AGENTS; CCAAT-BINDING FACTOR; CELL LINE, TUMOR; CELL PROLIFERATION; CONSERVED SEQUENCE; DIPHOSPHONATES; DNA PRIMERS; DNA, NEOPLASM; GENE KNOCKDOWN TECHNIQUES; GERANYLTRANSTRANSFERASE; HEPATOBLASTOMA; HUMANS; IMIDAZOLES; LIVER NEOPLASMS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROMOTER REGIONS, GENETIC; RNA, SMALL INTERFERING; SEQUENCE HOMOLOGY, NUCLEIC ACID; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; STEROLS; TRANSCRIPTIONAL ACTIVATION; TRANSFECTION;

EID: 77954748257     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20091511     Document Type: Article

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