The intracellular target for the antiresorptive aminobisphosphonate drugs in Dictyostelium discoideum is the enzyme farnesyl diphosphate synthase

Journal of Bone and Mineral Research

Volumn 15, Issue 5, 2000, Pages 971-981

  Grove, Joanna E ^a   Brown, Richard J ^a   Watts, Donald J ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Aminobisphosphonates; Dictyostelium; Farnesyl diphosphate synthase; Isoprenoids; Target

Indexed keywords

ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; GERANYLTRANSFERASE; RISEDRONIC ACID;

ARTICLE; DRUG MECHANISM; DRUG PROTEIN BINDING; NONHUMAN; OSTEOCLAST; OSTEOPOROSIS; STEROL SYNTHESIS; TARGET CELL;

EID: 0034056499     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2000.15.5.971     Document Type: Article

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