Modeling of the adrenergic response of the human IKs current (hKCNQ1/hKCNE1) stably expressed in HEK-293 cells

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 295, Issue 5, 2008, Pages

  Imredy, John P ^a   Penniman, Jacob R ^a   Dech, Spencer J ^a   Irving, Winston D ^a,b   Salata, Joseph J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b BETH ISRAEL MEDICAL CENTER   (United States)

Author keywords

adrenergic modulation; Human embryonic kidney 293 cells; KCNE1; KCNQ1; Slowly activating cardiac delayed rectifer potassium current

Indexed keywords

8 (4 CHLOROPHENYLTHIO) CYCLIC AMP; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLIC AMP; FORSKOLIN; ISOPRENALINE; POTASSIUM CHANNEL KCNE1; POTASSIUM CHANNEL KCNQ1;

ACTION POTENTIAL; ARTICLE; CHANNEL GATING; HEART MUSCLE CELL; HUMAN; HUMAN CELL; MATHEMATICAL MODEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TEMPERATURE DEPENDENCE;

ADENYLATE CYCLASE; ADRENERGIC BETA-AGONISTS; CELL LINE; CYCLIC AMP; ENZYME ACTIVATORS; FORSKOLIN; HUMANS; ION CHANNEL GATING; ISOPROTERENOL; KCNQ1 POTASSIUM CHANNEL; KINETICS; MEMBRANE POTENTIALS; MODELS, CARDIOVASCULAR; POTASSIUM; POTASSIUM CHANNELS, VOLTAGE-GATED; RECEPTORS, ADRENERGIC, BETA; RECOMBINANT PROTEINS; TEMPERATURE; THIONUCLEOTIDES; TRANSFECTION;

EID: 57049085145     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.433.2008     Document Type: Article

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