-
1
-
-
0033613334
-
Biliary tract cancers
-
de Groen PC, Gores GJ, LaRusso NF, Gunderson LL, Nagorney DM. Biliary tract cancers. N Engl J Med 1999; 341: 1368-78.
-
(1999)
N Engl J Med
, vol.341
, pp. 1368-1378
-
-
de Groen, P.C.1
Gores, G.J.2
Larusso, N.F.3
Gunderson, L.L.4
Nagorney, D.M.5
-
2
-
-
33745275877
-
Impact of classification of hilar cholangiocarcinomas (Klatskin tumors) on the incidence of intra- and extrahepatic cholangiocarcinoma in the United States
-
Welzel TM, McGlynn KA, Hsing AW, O'Brien TR, Pfeiffer RM. Impact of classification of hilar cholangiocarcinomas (Klatskin tumors) on the incidence of intra- and extrahepatic cholangiocarcinoma in the United States. J Natl Cancer Inst 2006; 98: 873-5.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 873-875
-
-
Welzel, T.M.1
McGlynn, K.A.2
Hsing, A.W.3
O'Brien, T.R.4
Pfeiffer, R.M.5
-
3
-
-
33745234796
-
Trends in the incidence of primary liver and biliary tract cancers in England and Wales 1971-2001
-
West J, Wood H, Logan RF, Quinn M, Aithal GP. Trends in the incidence of primary liver and biliary tract cancers in England and Wales 1971-2001. Br J Cancer 2006; 94: 1751-8.
-
(2006)
Br J Cancer
, vol.94
, pp. 1751-1758
-
-
West, J.1
Wood, H.2
Logan, R.F.3
Quinn, M.4
Aithal, G.P.5
-
4
-
-
9244260186
-
Natural history and prognostic factors in 305 Swedish patients with primary sclerosing cholangitis
-
Broome U, Olsson R, Loof L, et al. Natural history and prognostic factors in 305 Swedish patients with primary sclerosing cholangitis. Gut 1996; 38: 610-5.
-
(1996)
Gut
, vol.38
, pp. 610-615
-
-
Broome, U.1
Olsson, R.2
Loof, L.3
-
5
-
-
0029844933
-
Surgical treatment in proximal bile duct cancer. A single-center experience
-
Pichlmayr R, Weimann A, Klempnauer J, et al. Surgical treatment in proximal bile duct cancer. A single-center experience. Ann Surg 1996; 224: 628-38.
-
(1996)
Ann Surg
, vol.224
, pp. 628-638
-
-
Pichlmayr, R.1
Weimann, A.2
Klempnauer, J.3
-
6
-
-
0031697976
-
Treatment of hilar cholangiocarcinoma (Klatskin tumors) with hepatic resection or transplantation
-
Iwatsuki S, Todo S, Marsh JW, et al. Treatment of hilar cholangiocarcinoma (Klatskin tumors) with hepatic resection or transplantation. J Am Coll Surg 1998; 187: 358-64.
-
(1998)
J Am Coll Surg
, vol.187
, pp. 358-364
-
-
Iwatsuki, S.1
Todo, S.2
Marsh, J.W.3
-
7
-
-
10744225096
-
Spanish experience in liver transplantation for hilar and peripheral cholangiocarcinoma
-
Robles R, Figueras J, Turrion VS, et al. Spanish experience in liver transplantation for hilar and peripheral cholangiocarcinoma. Ann Surg 2004; 239: 265-71.
-
(2004)
Ann Surg
, vol.239
, pp. 265-271
-
-
Robles, R.1
Figueras, J.2
Turrion, V.S.3
-
8
-
-
27644571956
-
Extended indications in living donor liver transplantation: Bile duct cancer
-
Jonas S, Mittler J, Pascher A, et al. Extended indications in living donor liver transplantation: bile duct cancer. Transplantation 2005; 80: S101-4.
-
(2005)
Transplantation
, vol.80
-
-
Jonas, S.1
Mittler, J.2
Pascher, A.3
-
9
-
-
24944520148
-
Liver transplantation with neoadjuvant chemoradiation is more effective than resection for hilar cholangiocarcinoma
-
Rea DJ, Heimbach JK, Rosen CB, et al. Liver transplantation with neoadjuvant chemoradiation is more effective than resection for hilar cholangiocarcinoma. Ann Surg 2005; 242: 451-8.
-
(2005)
Ann Surg
, vol.242
, pp. 451-458
-
-
Rea, D.J.1
Heimbach, J.K.2
Rosen, C.B.3
-
10
-
-
4344617841
-
General principles of photodynamic therapy (PDT) and gastrointestinal applications
-
Wiedmann MW, Caca K. General principles of photodynamic therapy (PDT) and gastrointestinal applications. Curr Pharm Biotechnol 2004; 5: 397-408.
-
(2004)
Curr Pharm Biotechnol
, vol.5
, pp. 397-408
-
-
Wiedmann, M.W.1
Caca, K.2
-
11
-
-
18844429786
-
Molecularly targeted therapy for gastrointestinal cancer
-
Wiedmann MW, Caca K. Molecularly targeted therapy for gastrointestinal cancer. Curr Cancer Drug Targets 2005; 5: 171-93.
-
(2005)
Curr Cancer Drug Targets
, vol.5
, pp. 171-193
-
-
Wiedmann, M.W.1
Caca, K.2
-
12
-
-
0038645938
-
Identification of novel cellular targets in biliary tract cancers using global gene expression technology
-
Hansel DE, Rahman A, Hidalgo M, et al. Identification of novel cellular targets in biliary tract cancers using global gene expression technology. Am J Pathol 2003; 163: 217-29.
-
(2003)
Am J Pathol
, vol.163
, pp. 217-229
-
-
Hansel, D.E.1
Rahman, A.2
Hidalgo, M.3
-
13
-
-
0028271581
-
Strong promoting effect of Opisthorchis viverrini infection on dimethylnitrosamine-initiated hamster liver
-
Thamavit W, Pairojkul C, Tiwawech D, Shirai T, Ito N. Strong promoting effect of Opisthorchis viverrini infection on dimethylnitrosamine-initiated hamster liver. Cancer Lett 1994; 78: 121-5.
-
(1994)
Cancer Lett
, vol.78
, pp. 121-125
-
-
Thamavit, W.1
Pairojkul, C.2
Tiwawech, D.3
Shirai, T.4
Ito, N.5
-
14
-
-
0023201637
-
Level of Opisthorchis infestation and carcinogen dose-dependence of cholangiocarcinoma induction in Syrian golden hamsters
-
Thamavit W, Kongkanuntn R, Tiwawech D, Moore MA. Level of Opisthorchis infestation and carcinogen dose-dependence of cholangiocarcinoma induction in Syrian golden hamsters. Virchows Arch B Cell Pathol Incl Mol Pathol 1987; 54: 52-8.
-
(1987)
Virchows Arch B Cell Pathol Incl Mol Pathol
, vol.54
, pp. 52-58
-
-
Thamavit, W.1
Kongkanuntn, R.2
Tiwawech, D.3
Moore, M.A.4
-
15
-
-
0020964565
-
Promotion of N-nitrosodimethylamine- initiated bile duct carcinogenesis in the hamster by the human liver fluke, Opisthorchis viverrini
-
Flavell DJ, Lucas SB. Promotion of N-nitrosodimethylamine- initiated bile duct carcinogenesis in the hamster by the human liver fluke, Opisthorchis viverrini. Carcinogenesis 1983; 4: 927-30.
-
(1983)
Carcinogenesis
, vol.4
, pp. 927-930
-
-
Flavell, D.J.1
Lucas, S.B.2
-
16
-
-
0018128063
-
Effects of dimethylnitrosamine on induction of cholangiocarcinoma in Opisthorchis viverrini-infected Syrian golden hamsters
-
Thamavit W, Bhamarapravati N, Sahaphong S, Vajrasthira S, Angsubhakorn S. Effects of dimethylnitrosamine on induction of cholangiocarcinoma in Opisthorchis viverrini-infected Syrian golden hamsters. Cancer Res 1978; 38: 4634-9.
-
(1978)
Cancer Res
, vol.38
, pp. 4634-4639
-
-
Thamavit, W.1
Bhamarapravati, N.2
Sahaphong, S.3
Vajrasthira, S.4
Angsubhakorn, S.5
-
17
-
-
0020357762
-
Potentiation by the human liver fluke, Opisthorchis viverrini, of the carcinogenic action of N- nitrosodimethylamine upon the biliary epithelium of the hamster
-
Flavell DJ, Lucas SB. Potentiation by the human liver fluke, Opisthorchis viverrini, of the carcinogenic action of N- nitrosodimethylamine upon the biliary epithelium of the hamster. Br J Cancer 1982; 46: 985-9.
-
(1982)
Br J Cancer
, vol.46
, pp. 985-989
-
-
Flavell, D.J.1
Lucas, S.B.2
-
18
-
-
0027476172
-
Sirica AE. Intestinal-type of adenocarcinoma preferentially induced in right/caudate liver lobes of rats treated with furan
-
Elmore LW, Sirica AE. Intestinal-type of adenocarcinoma preferentially induced in right/caudate liver lobes of rats treated with furan. Cancer Res 1993; 53: 254-9.
-
(1993)
Cancer Res
, vol.53
, pp. 254-259
-
-
Elmore, L.W.1
-
19
-
-
3042818975
-
Thioacetamide- induced intestinal-type cholangiocarcinoma in rat: An animal model recapitulating the multi-stage progression of human cholangiocarcinoma
-
Yeh CN, Maitra A, Lee KF, Jan YY, Chen MF. Thioacetamide- induced intestinal-type cholangiocarcinoma in rat: an animal model recapitulating the multi-stage progression of human cholangiocarcinoma. Carcinogenesis 2004; 25: 631-6.
-
(2004)
Carcinogenesis
, vol.25
, pp. 631-636
-
-
Yeh, C.N.1
Maitra, A.2
Lee, K.F.3
Jan, Y.Y.4
Chen, M.F.5
-
20
-
-
0035476235
-
Constitutive expression of ErbB-2 in gallbladder epithelium results in development of adenocarcinoma
-
Kiguchi K, Carbajal S, Chan K, et al. Constitutive expression of ErbB-2 in gallbladder epithelium results in development of adenocarcinoma. Cancer Res 2001; 61: 6971-6.
-
(2001)
Cancer Res
, vol.61
, pp. 6971-6976
-
-
Kiguchi, K.1
Carbajal, S.2
Chan, K.3
-
21
-
-
11244335567
-
Cholangiocarcinoma: Molecular targeting strategies for chemoprevention and therapy
-
Sirica AE. Cholangiocarcinoma: molecular targeting strategies for chemoprevention and therapy. Hepatology 2005; 41: 5-15.
-
(2005)
Hepatology
, vol.41
, pp. 5-15
-
-
Sirica, A.E.1
-
22
-
-
0021273420
-
Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
-
Ullrich A, Coussens L, Hayflick JS, et al. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature 1984; 309: 418-25.
-
(1984)
Nature
, vol.309
, pp. 418-425
-
-
Ullrich, A.1
Coussens, L.2
Hayflick, J.S.3
-
23
-
-
18344390418
-
ERBB receptors and cancer: The complexity of targeted inhibitors
-
Hynes NE, Lane HA. ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer 2005; 5: 341-54.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 341-354
-
-
Hynes, N.E.1
Lane, H.A.2
-
24
-
-
0033757709
-
Epidermal growth factor receptor tyrosine kinase as a target for anticancer therapy
-
Raymond E, Faivre S, Armand JP. Epidermal growth factor receptor tyrosine kinase as a target for anticancer therapy. Drugs 2000; 60(Suppl 1): 15-23.
-
(2000)
Drugs
, vol.60
, Issue.SUPPL. 1
, pp. 15-23
-
-
Raymond, E.1
Faivre, S.2
Armand, J.P.3
-
25
-
-
1242329830
-
Epidermal growth factor receptor: A promising target in solid tumours
-
Laskin JJ, Sandler AB. Epidermal growth factor receptor: a promising target in solid tumours. Cancer Treat Rev 2004; 30: 1-17.
-
(2004)
Cancer Treat Rev
, vol.30
, pp. 1-17
-
-
Laskin, J.J.1
Sandler, A.B.2
-
26
-
-
0037296357
-
The epidermal growth factor receptor- tyrosine kinase: A promising therapeutic target in solid tumors
-
Ritter CA, Arteaga CL. The epidermal growth factor receptor- tyrosine kinase: a promising therapeutic target in solid tumors. Semin Oncol 2003; 30: 3-11.
-
(2003)
Semin Oncol
, vol.30
, pp. 3-11
-
-
Ritter, C.A.1
Arteaga, C.L.2
-
27
-
-
0032915392
-
Epidermal growth factor receptors: Critical mediators of multiple receptor pathways
-
Hackel PO, Zwick E, Prenzel N, Ullrich A. Epidermal growth factor receptors: critical mediators of multiple receptor pathways. Curr Opin Cell Biol 1999; 11: 184-9.
-
(1999)
Curr Opin Cell Biol
, vol.11
, pp. 184-189
-
-
Hackel, P.O.1
Zwick, E.2
Prenzel, N.3
Ullrich, A.4
-
28
-
-
0034644539
-
Cell signaling by receptor tyrosine kinases
-
Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell 2000; 103: 211-25.
-
(2000)
Cell
, vol.103
, pp. 211-225
-
-
Schlessinger, J.1
-
30
-
-
17844372539
-
Critical update and emerging trends in epidermal growth factor receptor targeting in cancer
-
Baselga J, Arteaga CL. Critical update and emerging trends in epidermal growth factor receptor targeting in cancer. J Clin Oncol 2005; 23: 2445-59.
-
(2005)
J Clin Oncol
, vol.23
, pp. 2445-2459
-
-
Baselga, J.1
Arteaga, C.L.2
-
31
-
-
40849147041
-
EGFR antagonists in cancer treatment
-
Ciardiello F, Tortora G. EGFR antagonists in cancer treatment. N Engl J Med 2008; 358: 1160-74.
-
(2008)
N Engl J Med
, vol.358
, pp. 1160-1174
-
-
Ciardiello, F.1
Tortora, G.2
-
32
-
-
0037698899
-
Cholangiocarcinoma: Current concepts and insights
-
Gores GJ. Cholangiocarcinoma: current concepts and insights. Hepatol 2003; 37: 961-9.
-
(2003)
Hepatol
, vol.37
, pp. 961-969
-
-
Gores, G.J.1
-
33
-
-
0032951925
-
Overexpression of C- NEU and C-MET during rat liver cholangiocarcinogenesis: A link between biliary intestinal metaplasia and mucin-producing cholan- giocarcinoma
-
Radaeva S, Ferreira-Gonzalez A, Sirica AE. Overexpression of C- NEU and C-MET during rat liver cholangiocarcinogenesis: A link between biliary intestinal metaplasia and mucin-producing cholan- giocarcinoma. Hepatology 1999; 29: 1453-62.
-
(1999)
Hepatology
, vol.29
, pp. 1453-1462
-
-
Radaeva, S.1
Ferreira-Gonzalez, A.2
Sirica, A.E.3
-
34
-
-
0036124041
-
c-erbB-2 and c-Met expression relates to cholangiocarcinogenesis and progression of intrahepatic cholangiocarcinoma
-
Aishima SI, Taguchi KI, Sugimachi K, Shimada M, Tsuneyoshi M. c-erbB-2 and c-Met expression relates to cholangiocarcinogenesis and progression of intrahepatic cholangiocarcinoma. Histopathology 2002; 40: 269-78.
-
(2002)
Histopathology
, vol.40
, pp. 269-278
-
-
Aishima, S.I.1
Taguchi, K.I.2
Sugimachi, K.3
Shimada, M.4
Tsuneyoshi, M.5
-
35
-
-
0035118561
-
Expression and clinical signi- ficance of the erbB family in intrahepatic cholangiocellular carcinoma
-
Ito Y, Takeda T, Sasaki Y, et al. Expression and clinical signi- ficance of the erbB family in intrahepatic cholangiocellular carcinoma. Pathol Res Pract 2001; 197: 95-100.
-
(2001)
Pathol Res Pract
, vol.197
, pp. 95-100
-
-
Ito, Y.1
Takeda, T.2
Sasaki, Y.3
-
36
-
-
0031770247
-
Endo K, et al. c-erbB-2 protein is expressed in hepatolithiasis and cholangiocarcinoma
-
Terada T, Ashida K, Endo K, et al. c-erbB-2 protein is expressed in hepatolithiasis and cholangiocarcinoma. Histopathology 1998; 33: 325-31.
-
(1998)
Histopathology
, vol.33
, pp. 325-331
-
-
Terada, T.1
Ashida, K.2
-
37
-
-
0036623359
-
Gene amplification and mRNA and protein overexpression of c-erbB-2 (HER-2/neu) in human intra- hepatic cholangiocarcinoma as detected by fluorescence in situ hybridization, in situ hybridization, and immunohistochemistry
-
Ukita Y, Kato M, Terada T. Gene amplification and mRNA and protein overexpression of c-erbB-2 (HER-2/neu) in human intra- hepatic cholangiocarcinoma as detected by fluorescence in situ hybridization, in situ hybridization, and immunohistochemistry. J Hepatol 2002; 36: 780-5.
-
(2002)
J Hepatol
, vol.36
, pp. 780-785
-
-
Ukita, Y.1
Kato, M.2
Terada, T.3
-
38
-
-
21344438897
-
Amplification and overexpression of c-erbB-2, epidermal growth factor receptor, and c-met in biliary tract cancers
-
Nakazawa K, Dobashi Y, Suzuki S, Fujii H, Takeda Y, Ooi A. Amplification and overexpression of c-erbB-2, epidermal growth factor receptor, and c-met in biliary tract cancers. J Pathol 2005; 206: 356-65.
-
(2005)
J Pathol
, vol.206
, pp. 356-365
-
-
Nakazawa, K.1
Dobashi, Y.2
Suzuki, S.3
Fujii, H.4
Takeda, Y.5
Ooi, A.6
-
39
-
-
38549139744
-
Clinicopathological and prognostic significance of EGFR, VEGF, and HER2 expression in cholangiocarcinoma
-
Yoshikawa D, Ojima H, Iwasaki M, et al. Clinicopathological and prognostic significance of EGFR, VEGF, and HER2 expression in cholangiocarcinoma. Br J Cancer 2008; 98: 418-25.
-
(2008)
Br J Cancer
, vol.98
, pp. 418-425
-
-
Yoshikawa, D.1
Ojima, H.2
Iwasaki, M.3
-
40
-
-
0142024103
-
Investigation of ErbB1 and ErbB2 expression for therapeutic targeting in primary liver tumours
-
Altimari A, Fiorentino M, Gabusi E, et al. Investigation of ErbB1 and ErbB2 expression for therapeutic targeting in primary liver tumours. Dig Liver Dis 2003; 35: 332-8.
-
(2003)
Dig Liver Dis
, vol.35
, pp. 332-338
-
-
Altimari, A.1
Fiorentino, M.2
Gabusi, E.3
-
41
-
-
33748169241
-
Novel targeted approaches to treating biliary tract cancer: The dual epidermal growth factor receptor and ErbB-2 tyrosine kinase inhibitor NVP- AEE788 is more efficient than the epidermal growth factor receptor inhibitors gefitinib and erlotinib
-
Wiedmann M, Feisthammel J, Bluthner T, et al. Novel targeted approaches to treating biliary tract cancer: the dual epidermal growth factor receptor and ErbB-2 tyrosine kinase inhibitor NVP- AEE788 is more efficient than the epidermal growth factor receptor inhibitors gefitinib and erlotinib. Anticancer Drugs 2006; 17: 783-95.
-
(2006)
Anticancer Drugs
, vol.17
, pp. 783-795
-
-
Wiedmann, M.1
Feisthammel, J.2
Bluthner, T.3
-
42
-
-
34548099256
-
Expression of c-erbB-2 proto-oncogene in extrahepatic cholangiocarcinoma and its clinical significance
-
Zheng J, Zhu YM. Expression of c-erbB-2 proto-oncogene in extrahepatic cholangiocarcinoma and its clinical significance. Hepatobiliary Pancreat Dis Int 2007; 6: 412-5.
-
(2007)
Hepatobiliary Pancreat Dis Int
, vol.6
, pp. 412-415
-
-
Zheng, J.1
Zhu, Y.M.2
-
43
-
-
0036322129
-
ERBB-2 overexpression and cyclooxygenase-2 up-regulation in human cholangiocarcinoma and risk conditions
-
Endo K, Yoon BI, Pairojkul C, Demetris AJ, Sirica AE. ERBB-2 overexpression and cyclooxygenase-2 up-regulation in human cholangiocarcinoma and risk conditions. Hepatol 2002; 36: 439-50.
-
(2002)
Hepatol
, vol.36
, pp. 439-450
-
-
Endo, K.1
Yoon, B.I.2
Pairojkul, C.3
Demetris, A.J.4
Sirica, A.E.5
-
44
-
-
0031912249
-
Immunohistochemical demons- tration of MET overexpression in human intrahepatic cholangio- carcinoma and in hepatolithiasis
-
Terada T, Nakanuma Y, Sirica AE. Immunohistochemical demons- tration of MET overexpression in human intrahepatic cholangio- carcinoma and in hepatolithiasis. Hum Pathol 1998; 29: 175-80.
-
(1998)
Hum Pathol
, vol.29
, pp. 175-180
-
-
Terada, T.1
Nakanuma, Y.2
Sirica, A.E.3
-
45
-
-
0030689866
-
NEU overexpression in the furan rat model of cholangiocarcinogenesis compared with biliary ductal cell hyperplasia
-
Sirica AE, Radaeva S, Caran N. NEU overexpression in the furan rat model of cholangiocarcinogenesis compared with biliary ductal cell hyperplasia. Am J Pathol 1997; 151: 1685-94.
-
(1997)
Am J Pathol
, vol.151
, pp. 1685-1694
-
-
Sirica, A.E.1
Radaeva, S.2
Caran, N.3
-
46
-
-
0027533199
-
Promoting effects of bile acid load on the occurrence of cholangiocarcinoma induced by diisopropanolnitrosamine in hamsters
-
Kinami Y, Ashida Y, Gotoda H, Seto K, Kojima Y, Takashima S. Promoting effects of bile acid load on the occurrence of cholangiocarcinoma induced by diisopropanolnitrosamine in hamsters. Oncology 1993; 50: 46-51.
-
(1993)
Oncology
, vol.50
, pp. 46-51
-
-
Kinami, Y.1
Ashida, Y.2
Gotoda, H.3
Seto, K.4
Kojima, Y.5
Takashima, S.6
-
47
-
-
0036208350
-
Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line
-
Yoon JH, Higuchi H, Werneburg NW, Kaufmann SH, Gores GJ. Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line. Gastroenterology 2002; 122: 985-93.
-
(2002)
Gastroenterology
, vol.122
, pp. 985-993
-
-
Yoon, J.H.1
Higuchi, H.2
Werneburg, N.W.3
Kaufmann, S.H.4
Gores, G.J.5
-
49
-
-
0037112523
-
Bile acids inhibit Mcl- 1 protein turnover via an epidermal growth factor receptor/Raf-1- dependent mechanism
-
Yoon JH, Werneburg NW, Higuchi H, et al. Bile acids inhibit Mcl- 1 protein turnover via an epidermal growth factor receptor/Raf-1- dependent mechanism. Cancer Res 2002; 62: 6500-5.
-
(2002)
Cancer Res
, vol.62
, pp. 6500-6505
-
-
Yoon, J.H.1
Werneburg, N.W.2
Higuchi, H.3
-
50
-
-
33745970752
-
Phase II study of erlotinib in patients with advanced biliary cancer
-
Philip PA, Mahoney MR, Allmer C, et al. Phase II study of erlotinib in patients with advanced biliary cancer. J Clin Oncol 2006; 24: 3069-74.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3069-3074
-
-
Philip, P.A.1
Mahoney, M.R.2
Allmer, C.3
-
51
-
-
34248398120
-
Erlotinib plus gemcitabine in patients with unresectable pancreatic cancer and other solid tumors: Phase IB trial
-
Dragovich T, Huberman M, Von Hoff DD, et al. Erlotinib plus gemcitabine in patients with unresectable pancreatic cancer and other solid tumors: phase IB trial. Cancer Chemother Pharmacol 2007; 60: 295-303.
-
(2007)
Cancer Chemother Pharmacol
, vol.60
, pp. 295-303
-
-
Dragovich, T.1
Huberman, M.2
von Hoff, D.D.3
-
52
-
-
37049013090
-
Cetuximab plus gemcitabine- oxaliplatin (GEMOX) in patients with refractory advanced intrahepatic cholangiocarcinomas
-
Paule B, Herelle MO, Rage E, et al. Cetuximab plus gemcitabine- oxaliplatin (GEMOX) in patients with refractory advanced intrahepatic cholangiocarcinomas. Oncology 2007; 72: 105-10.
-
(2007)
Oncology
, vol.72
, pp. 105-110
-
-
Paule, B.1
Herelle, M.O.2
Rage, E.3
-
53
-
-
51449101007
-
Gemcitabine and oxaliplatin in advanced biliary tract carcinoma: A phase II study
-
Andre T, Reyes-Vidal JM, Fartoux L, et al. Gemcitabine and oxaliplatin in advanced biliary tract carcinoma: a phase II study. Br J Cancer 2008; 99: 862-7.
-
(2008)
Br J Cancer
, vol.99
, pp. 862-867
-
-
Andre, T.1
Reyes-Vidal, J.M.2
Fartoux, L.3
-
54
-
-
42049109155
-
Lapatinib/gemcitabine and lapatinib/gemcitabine/oxaliplatin: A phase I study for advanced pancreaticobiliary cancer
-
Safran H, Miner T, Resnick M, et al. Lapatinib/gemcitabine and lapatinib/gemcitabine/oxaliplatin: a phase I study for advanced pancreaticobiliary cancer. Am J Clin Oncol 2008; 31: 140-4.
-
(2008)
Am J Clin Oncol
, vol.31
, pp. 140-144
-
-
Safran, H.1
Miner, T.2
Resnick, M.3
-
55
-
-
32944461545
-
Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2- overexpressing and trastuzumab-treated breast cancer cells
-
Konecny GE, Pegram MD, Venkatesan N, et al. Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2- overexpressing and trastuzumab-treated breast cancer cells. Cancer Res 2006; 66: 1630-9.
-
(2006)
Cancer Res
, vol.66
, pp. 1630-1639
-
-
Konecny, G.E.1
Pegram, M.D.2
Venkatesan, N.3
-
56
-
-
27544503230
-
Gefitinib plus best supportive care in previously treated patients with refractory advanced non- small-cell lung cancer: Results from a randomised, placebo- controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)
-
Thatcher N, Chang A, Parikh P, et al. Gefitinib plus best supportive care in previously treated patients with refractory advanced non- small-cell lung cancer: results from a randomised, placebo- controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer). Lancet 2005; 366: 1527-37.
-
(2005)
Lancet
, vol.366
, pp. 1527-1537
-
-
Thatcher, N.1
Chang, A.2
Parikh, P.3
-
57
-
-
22044445517
-
Erlotinib in previously treated non-small-cell lung cancer
-
Shepherd FA, Rodrigues Pereira J, Ciuleanu T, et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005; 353: 123-32.
-
(2005)
N Engl J Med
, vol.353
, pp. 123-132
-
-
Shepherd, F.A.1
Rodrigues Pereira, J.2
Ciuleanu, T.3
-
58
-
-
3242720345
-
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
-
Cunningham D, Humblet Y, Siena S, et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 2004; 351: 337-45.
-
(2004)
N Engl J Med
, vol.351
, pp. 337-345
-
-
Cunningham, D.1
Humblet, Y.2
Siena, S.3
-
59
-
-
32144433159
-
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
-
Bonner JA, Harari PM, Giralt J, et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 2006; 354: 567-78.
-
(2006)
N Engl J Med
, vol.354
, pp. 567-578
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
-
60
-
-
34249933404
-
Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group
-
Moore MJ, Goldstein D, Hamm J, et al. Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 2007; 25: 1960-6.
-
(2007)
J Clin Oncol
, vol.25
, pp. 1960-1966
-
-
Moore, M.J.1
Goldstein, D.2
Hamm, J.3
-
61
-
-
34249723218
-
Cetuximab, a chimeric human mouse anti-epidermal growth factor receptor monoclonal antibody, in the treatment of human colorectal cancer
-
Galizia G, Lieto E, De Vita F, et al. Cetuximab, a chimeric human mouse anti-epidermal growth factor receptor monoclonal antibody, in the treatment of human colorectal cancer. Oncogene 2007; 26: 3654-60.
-
(2007)
Oncogene
, vol.26
, pp. 3654-3660
-
-
Galizia, G.1
Lieto, E.2
de Vita, F.3
-
62
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non- small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non- small-cell lung cancer to gefitinib. N Engl J Med 2004; 350: 2129-39.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
63
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004; 304: 1497-500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
64
-
-
33645689431
-
Somatic mutations of epidermal growth factor receptor in bile duct and gallbladder carcinoma
-
Leone F, Cavalloni G, Pignochino Y, et al. Somatic mutations of epidermal growth factor receptor in bile duct and gallbladder carcinoma. Clin Cancer Res 2006; 12: 1680-5.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1680-1685
-
-
Leone, F.1
Cavalloni, G.2
Pignochino, Y.3
-
65
-
-
27144523155
-
Detection of response- predicting mutations in the kinase domain of the epidermal growth factor receptor gene in cholangiocarcinomas
-
Gwak GY, Yoon JH, Shin CM, et al. Detection of response- predicting mutations in the kinase domain of the epidermal growth factor receptor gene in cholangiocarcinomas. J Cancer Res Clin Oncol 2005; 131: 649-52.
-
(2005)
J Cancer Res Clin Oncol
, vol.131
, pp. 649-652
-
-
Gwak, G.Y.1
Yoon, J.H.2
Shin, C.M.3
-
66
-
-
54949085398
-
K-ras mutations and benefit from cetuximab in advanced colorectal cancer
-
Karapetis CS, Khambata-Ford S, Jonker DJ, et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med 2008; 359: 1757-65.
-
(2008)
N Engl J Med
, vol.359
, pp. 1757-1765
-
-
Karapetis, C.S.1
Khambata-Ford, S.2
Jonker, D.J.3
-
67
-
-
42649145667
-
Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
-
Amado RG, Wolf M, Peeters M, et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 2008; 26: 1626-34.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1626-1634
-
-
Amado, R.G.1
Wolf, M.2
Peeters, M.3
-
68
-
-
39849090322
-
Genetic changes of p53, K- ras, and microsatellite instability in gallbladder carcinoma in high- incidence areas of Japan and Hungary
-
Nagahashi M, Ajioka Y, Lang I, et al. Genetic changes of p53, K- ras, and microsatellite instability in gallbladder carcinoma in high- incidence areas of Japan and Hungary. World J Gastroenterol 2008; 14: 70-5.
-
(2008)
World J Gastroenterol
, vol.14
, pp. 70-75
-
-
Nagahashi, M.1
Ajioka, Y.2
Lang, I.3
-
69
-
-
12344317992
-
K-ras gene mutation in gallbladder carcinoma
-
Roa JC, Roa I, de Aretxabala X, Melo A, Faria G, Tapia O. [K-ras gene mutation in gallbladder carcinoma]. Rev Med Chil 2004; 132: 955-60.
-
(2004)
Rev Med Chil
, vol.132
, pp. 955-960
-
-
Roa, J.C.1
Roa, I.2
de Aretxabala, X.3
Melo, A.4
Faria, G.5
Tapia, O.6
-
70
-
-
4143052338
-
Mutational spectrum of K-ras oncogene among Indian patients with gallbladder cancer
-
Singh MK, Chetri K, Pandey UB, Kapoor VK, Mittal B, Choudhuri G. Mutational spectrum of K-ras oncogene among Indian patients with gallbladder cancer. J Gastroenterol Hepatol 2004; 19: 916-21.
-
(2004)
J Gastroenterol Hepatol
, vol.19
, pp. 916-921
-
-
Singh, M.K.1
Chetri, K.2
Pandey, U.B.3
Kapoor, V.K.4
Mittal, B.5
Choudhuri, G.6
-
71
-
-
0942264824
-
Mutation analysis of K-ras and beta-catenin genes related to O6-methylguanin-DNA methyltransferase and mismatch repair protein status in human gallbladder carcinoma
-
Kohya N, Kitajima Y, Kitahara K, Miyazaki K. Mutation analysis of K-ras and beta-catenin genes related to O6-methylguanin-DNA methyltransferase and mismatch repair protein status in human gallbladder carcinoma. Int J Mol Med 2003; 11: 65-9.
-
(2003)
Int J Mol Med
, vol.11
, pp. 65-69
-
-
Kohya, N.1
Kitajima, Y.2
Kitahara, K.3
Miyazaki, K.4
-
72
-
-
0034518430
-
K-ras oncogene mutation in cancer and precancerous lesions of the gallbladder
-
Kim SW, Her KH, Jang JY, Kim WH, Kim YT, Park YH. K-ras oncogene mutation in cancer and precancerous lesions of the gallbladder. J Surg Oncol 2000; 75: 246-51.
-
(2000)
J Surg Oncol
, vol.75
, pp. 246-251
-
-
Kim, S.W.1
Her, K.H.2
Jang, J.Y.3
Kim, W.H.4
Kim, Y.T.5
Park, Y.H.6
-
73
-
-
0029901707
-
APC, K-ras codon 12 mutations and p53 gene expression in carcinoma and adenoma of the gall-bladder suggest two genetic pathways in gall-bladder carcinogenesis
-
Itoi T, Watanabe H, Ajioka Y, et al. APC, K-ras codon 12 mutations and p53 gene expression in carcinoma and adenoma of the gall-bladder suggest two genetic pathways in gall-bladder carcinogenesis. Pathol Int 1996; 46: 333-40.
-
(1996)
Pathol Int
, vol.46
, pp. 333-340
-
-
Itoi, T.1
Watanabe, H.2
Ajioka, Y.3
-
74
-
-
0029978040
-
K-ras gene mutation in gall bladder carcinomas and dysplasia
-
Ajiki T, Fujimori T, Onoyama H, et al. K-ras gene mutation in gall bladder carcinomas and dysplasia. Gut 1996; 38: 426-9.
-
(1996)
Gut
, vol.38
, pp. 426-429
-
-
Ajiki, T.1
Fujimori, T.2
Onoyama, H.3
-
75
-
-
0036016638
-
Analysis of microsatellite instability, K-ras gene mutation and p53 protein overexpression in intrahepatic cholangiocarcinoma
-
Isa T, Tomita S, Nakachi A, et al. Analysis of microsatellite instability, K-ras gene mutation and p53 protein overexpression in intrahepatic cholangiocarcinoma. Hepatogastroenterol 2002; 49: 604-8.
-
(2002)
Hepatogastroenterol
, vol.49
, pp. 604-608
-
-
Isa, T.1
Tomita, S.2
Nakachi, A.3
-
76
-
-
0033756536
-
Frequency of p16(INK4A) alterations and K-ras mutations in intrahepatic cholangiocarcinoma of the liver
-
Tannapfel A, Benicke M, Katalinic A, et al. Frequency of p16(INK4A) alterations and K-ras mutations in intrahepatic cholangiocarcinoma of the liver. Gut 2000; 47: 721-7.
-
(2000)
Gut
, vol.47
, pp. 721-727
-
-
Tannapfel, A.1
Benicke, M.2
Katalinic, A.3
-
77
-
-
0032874377
-
Protein expression and genetic alterations of p53 and ras in intrahepatic cholangiocarcinoma
-
Furubo S, Harada K, Shimonishi T, Katayanagi K, Tsui W, Nakanuma Y. Protein expression and genetic alterations of p53 and ras in intrahepatic cholangiocarcinoma. Histopathology 1999; 35: 230-40.
-
(1999)
Histopathology
, vol.35
, pp. 230-240
-
-
Furubo, S.1
Harada, K.2
Shimonishi, T.3
Katayanagi, K.4
Tsui, W.5
Nakanuma, Y.6
-
78
-
-
0345369550
-
Mutation of p53 and K-ras, and loss of heterozygosity of APC in intrahepatic cholangiocarcinoma
-
Kang YK, Kim WH, Lee HW, Lee HK, Kim YI. Mutation of p53 and K-ras, and loss of heterozygosity of APC in intrahepatic cholangiocarcinoma. Lab Invest 1999; 79: 477-83.
-
(1999)
Lab Invest
, vol.79
, pp. 477-483
-
-
Kang, Y.K.1
Kim, W.H.2
Lee, H.W.3
Lee, H.K.4
Kim, Y.I.5
-
79
-
-
0026547213
-
High incidence of ras gene mutation in intrahepatic cholangiocarcinoma
-
Tada M, Omata M, Ohto M. High incidence of ras gene mutation in intrahepatic cholangiocarcinoma. Cancer 1992; 69: 1115-8.
-
(1992)
Cancer
, vol.69
, pp. 1115-1118
-
-
Tada, M.1
Omata, M.2
Ohto, M.3
-
80
-
-
0034576378
-
p53 overexpression and K-ras gene mutations in primary sclerosing cholangitis-associated biliary tract cancer
-
Ahrendt SA, Rashid A, Chow JT, Eisenberger CF, Pitt HA, Sidransky D. p53 overexpression and K-ras gene mutations in primary sclerosing cholangitis-associated biliary tract cancer. J Hepatobiliary Pancreat Surg 2000; 7: 426-31.
-
(2000)
J Hepatobiliary Pancreat Surg
, vol.7
, pp. 426-431
-
-
Ahrendt, S.A.1
Rashid, A.2
Chow, J.T.3
Eisenberger, C.F.4
Pitt, H.A.5
Sidransky, D.6
-
81
-
-
0034053517
-
Cholangiocarcinoma in primary sclerosing cholangitis: K-ras mutations and Tp53 dysfunction are implicated in the neoplastic development
-
Boberg KM, Schrumpf E, Bergquist A, et al. Cholangiocarcinoma in primary sclerosing cholangitis: K-ras mutations and Tp53 dysfunction are implicated in the neoplastic development. J Hepatol 2000; 32: 374-80.
-
(2000)
J Hepatol
, vol.32
, pp. 374-380
-
-
Boberg, K.M.1
Schrumpf, E.2
Bergquist, A.3
-
82
-
-
13844317894
-
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
-
Kobayashi S, Boggon TJ, Dayaram T, et al. EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N Engl J Med 2005; 352: 786-92.
-
(2005)
N Engl J Med
, vol.352
, pp. 786-792
-
-
Kobayashi, S.1
Boggon, T.J.2
Dayaram, T.3
-
83
-
-
18244371651
-
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
-
Pao W, Miller VA, Politi KA, et al. Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLoS Med 2005; 2: e73.
-
(2005)
PLoS Med
, vol.2
-
-
Pao, W.1
Miller, V.A.2
Politi, K.A.3
-
84
-
-
33750302365
-
Analysis of epidermal growth factor receptor gene mutation in patients with non-small cell lung cancer and acquired resistance to gefitinib
-
Kosaka T, Yatabe Y, Endoh H, et al. Analysis of epidermal growth factor receptor gene mutation in patients with non-small cell lung cancer and acquired resistance to gefitinib. Clin Cancer Res 2006; 12: 5764-9.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5764-5769
-
-
Kosaka, T.1
Yatabe, Y.2
Endoh, H.3
-
85
-
-
33847406095
-
Structures of lung cancer-derived EGFR mutants and inhibitor complexes: Mechanism of activation and insights into differential inhibitor sensitivity
-
Yun CH, Boggon TJ, Li Y, et al. Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity. Cancer Cell 2007; 11: 217-27.
-
(2007)
Cancer Cell
, vol.11
, pp. 217-227
-
-
Yun, C.H.1
Boggon, T.J.2
Li, Y.3
-
86
-
-
34548668194
-
Histone deacetylase inhibitor MS-275 alone or combined with bortezomib or sorafenib exhibits strong antiproliferative action in human cholangiocarcinoma cells
-
Baradari V, Hopfner M, Huether A, Schuppan D, Scherubl H. Histone deacetylase inhibitor MS-275 alone or combined with bortezomib or sorafenib exhibits strong antiproliferative action in human cholangiocarcinoma cells. World J Gastroenterol 2007; 13: 4458-66.
-
(2007)
World J Gastroenterol
, vol.13
, pp. 4458-4466
-
-
Baradari, V.1
Hopfner, M.2
Huether, A.3
Schuppan, D.4
Scherubl, H.5
-
87
-
-
33947516495
-
Proteasome inhibition-induces endoplasmic reticulum dysfunction and cell death of human cholangiocarcinoma cells
-
Ustundag Y, Bronk SF, Gores GJ. Proteasome inhibition-induces endoplasmic reticulum dysfunction and cell death of human cholangiocarcinoma cells. World J Gastroenterol 2007; 13: 851-7.
-
(2007)
World J Gastroenterol
, vol.13
, pp. 851-857
-
-
Ustundag, Y.1
Bronk, S.F.2
Gores, G.J.3
-
88
-
-
0037186924
-
Imatinib mesylate--a new oral targeted therapy
-
Savage DG, Antman KH. Imatinib mesylate--a new oral targeted therapy. N Engl J Med 2002; 346: 683-93.
-
(2002)
N Engl J Med
, vol.346
, pp. 683-693
-
-
Savage, D.G.1
Antman, K.H.2
-
89
-
-
4043134677
-
Novel mode of action of c-kit tyrosine kinase inhibitors leading to NK cell-dependent antitumor effects
-
Borg C, Terme M, Taieb J, et al. Novel mode of action of c-kit tyrosine kinase inhibitors leading to NK cell-dependent antitumor effects. J Clin Invest 2004; 114: 379-88.
-
(2004)
J Clin Invest
, vol.114
, pp. 379-388
-
-
Borg, C.1
Terme, M.2
Taieb, J.3
-
90
-
-
20344374146
-
Imatinib mesylate (Gleevec) downregulates telomerase activity and inhibits proliferation in telomerase-expressing cell lines
-
Uziel O, Fenig E, Nordenberg J, et al. Imatinib mesylate (Gleevec) downregulates telomerase activity and inhibits proliferation in telomerase-expressing cell lines. Br J Cancer 2005; 92: 1881-91.
-
(2005)
Br J Cancer
, vol.92
, pp. 1881-1891
-
-
Uziel, O.1
Fenig, E.2
Nordenberg, J.3
-
91
-
-
34548580286
-
Treatment with imatinib improves drug delivery and efficacy in NSCLC xenografts
-
Vlahovic G, Ponce AM, Rabbani Z, et al. Treatment with imatinib improves drug delivery and efficacy in NSCLC xenografts. Br J Cancer 2007; 97: 735-40.
-
(2007)
Br J Cancer
, vol.97
, pp. 735-740
-
-
Vlahovic, G.1
Ponce, A.M.2
Rabbani, Z.3
-
92
-
-
0142124896
-
Expression of Kit and platelet-derived growth factor receptors alpha and beta in cholangiocarcinoma, and case report of therapy with imatinib mesylate (STI571)
-
Holcombe RF, Gu M, Imagawa D, Milovanovic T. Expression of Kit and platelet-derived growth factor receptors alpha and beta in cholangiocarcinoma, and case report of therapy with imatinib mesylate (STI571). Anticancer Drugs 2003; 14: 651-7.
-
(2003)
Anticancer Drugs
, vol.14
, pp. 651-657
-
-
Holcombe, R.F.1
Gu, M.2
Imagawa, D.3
Milovanovic, T.4
-
93
-
-
0242319835
-
Imatinib mesylate (STI571; Glivec)--a new approach in the treatment of biliary tract cancer?
-
Wiedmann M, Kreth F, Feisthammel J, Deininger M, Mossner J, Caca K. Imatinib mesylate (STI571; Glivec)--a new approach in the treatment of biliary tract cancer? Anticancer Drugs 2003; 14: 751-60.
-
(2003)
Anticancer Drugs
, vol.14
, pp. 751-760
-
-
Wiedmann, M.1
Kreth, F.2
Feisthammel, J.3
Deininger, M.4
Mossner, J.5
Caca, K.6
-
94
-
-
11144314128
-
Imatinib mesylate induces apoptosis in human cholangiocarcinoma cells
-
Chiorean MV, Guicciardi ME, Yoon JH, Bronk SF, Kaufmanns SH, Gores GJ. Imatinib mesylate induces apoptosis in human cholangiocarcinoma cells. Liver Int 2004; 24: 687-95.
-
(2004)
Liver Int
, vol.24
, pp. 687-695
-
-
Chiorean, M.V.1
Guicciardi, M.E.2
Yoon, J.H.3
Bronk, S.F.4
Kaufmanns, S.H.5
Gores, G.J.6
-
95
-
-
33645741479
-
Expression of c-kit receptor in human cholangiocar- cinoma and in vivo treatment with imatinib mesilate in chimeric mice
-
Kamenz T, Caca K, Bluthner T, Tannapfel A, Mossner J, Wiedmann M. Expression of c-kit receptor in human cholangiocar- cinoma and in vivo treatment with imatinib mesilate in chimeric mice. World J Gastroenterol 2006; 12: 1583-90.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 1583-1590
-
-
Kamenz, T.1
Caca, K.2
Bluthner, T.3
Tannapfel, A.4
Mossner, J.5
Wiedmann, M.6
-
96
-
-
16644381251
-
KIT and platelet- derived growth factor receptor alpha tyrosine kinase gene mutations and KIT amplifications in human solid tumors
-
Sihto H, Sarlomo-Rikala M, Tynninen O, et al. KIT and platelet- derived growth factor receptor alpha tyrosine kinase gene mutations and KIT amplifications in human solid tumors. J Clin Oncol 2005; 23(1): 49-57.
-
(2005)
J Clin Oncol
, vol.23
, Issue.1
, pp. 49-57
-
-
Sihto, H.1
Sarlomo-Rikala, M.2
Tynninen, O.3
-
97
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
Druker BJ, Tamura S, Buchdunger E, et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med 1996; 2: 561-6.
-
(1996)
Nat Med
, vol.2
, pp. 561-566
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
-
98
-
-
43249095919
-
Tumor angiogenesis
-
Kerbel RS. Tumor angiogenesis. N Engl J Med 2008; 358: 2039-49.
-
(2008)
N Engl J Med
, vol.358
, pp. 2039-2049
-
-
Kerbel, R.S.1
-
99
-
-
0032774271
-
Vascular endothelial growth factor expression is an independent negative predictor in extra- hepatic biliary tract carcinomas
-
Hida Y, Morita T, Fujita M, et al. Vascular endothelial growth factor expression is an independent negative predictor in extra- hepatic biliary tract carcinomas. Anticancer Res 1999; 19: 2257-60.
-
(1999)
Anticancer Res
, vol.19
, pp. 2257-2260
-
-
Hida, Y.1
Morita, T.2
Fujita, M.3
-
100
-
-
34548615691
-
Evaluation of VEGF A expression and microvascular density as prognostic factors in extra- hepatic cholangiocarcinoma
-
Mobius C, Demuth C, Aigner T, et al. Evaluation of VEGF A expression and microvascular density as prognostic factors in extra- hepatic cholangiocarcinoma. Eur J Surg Oncol 2007; 33: 1025-9.
-
(2007)
Eur J Surg Oncol
, vol.33
, pp. 1025-1029
-
-
Mobius, C.1
Demuth, C.2
Aigner, T.3
-
101
-
-
33645737997
-
Angiogenesis in cholangio- cellular carcinoma: Expression of vascular endothelial growth factor, angiopoietin-1/2, thrombospondin-1 and clinicopathological significance
-
Tang D, Nagano H, Yamamoto H, et al. Angiogenesis in cholangio- cellular carcinoma: expression of vascular endothelial growth factor, angiopoietin-1/2, thrombospondin-1 and clinicopathological significance. Oncol Rep 2006; 15: 525-32.
-
(2006)
Oncol Rep
, vol.15
, pp. 525-532
-
-
Tang, D.1
Nagano, H.2
Yamamoto, H.3
-
102
-
-
33645664294
-
Rapid resolution of liver metastasis from cholangiocarcinoma after bevacizumab with cisplatin and high-dose fluorouracil plus leucovorin
-
Tai CJ, Chiou HY, Wu CH, Pan S, Liu JD. Rapid resolution of liver metastasis from cholangiocarcinoma after bevacizumab with cisplatin and high-dose fluorouracil plus leucovorin. Onkologie 2006; 29: 179-80.
-
(2006)
Onkologie
, vol.29
, pp. 179-180
-
-
Tai, C.J.1
Chiou, H.Y.2
Wu, C.H.3
Pan, S.4
Liu, J.D.5
-
103
-
-
0037624602
-
Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinoma
-
Tannapfel A, Sommerer F, Benicke M, et al. Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinoma. Gut 2003; 52: 706-12.
-
(2003)
Gut
, vol.52
, pp. 706-712
-
-
Tannapfel, A.1
Sommerer, F.2
Benicke, M.3
-
104
-
-
73149102791
-
Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2
-
Blechacz BR, Smoot RL, Bronk SF, Werneburg NW, Sirica AE, Gores GJ. Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2. Hepatol 2009; 50: 1861-70.
-
(2009)
Hepatol
, vol.50
, pp. 1861-1870
-
-
Blechacz, B.R.1
Smoot, R.L.2
Bronk, S.F.3
Werneburg, N.W.4
Sirica, A.E.5
Gores, G.J.6
-
105
-
-
74249098818
-
Sorafenib in patients with advanced biliary tract carcinoma: A phase II trial
-
Bengala C, Bertolini F, Malavasi N, et al. Sorafenib in patients with advanced biliary tract carcinoma: a phase II trial. Br J Cancer 2009; 102: 68-72.
-
(2009)
Br J Cancer
, vol.102
, pp. 68-72
-
-
Bengala, C.1
Bertolini, F.2
Malavasi, N.3
-
106
-
-
0029038336
-
Nagorney DM. Natural history of unresected cholangiocarcinoma: Patient outcome after noncurative intervention
-
Farley DR, Weaver AL, Nagorney DM. Natural history of unresected cholangiocarcinoma: patient outcome after noncurative intervention. Mayo Clin Proc 1995; 70: 425-9.
-
(1995)
Mayo Clin Proc
, vol.70
, pp. 425-429
-
-
Farley, D.R.1
Weaver, A.L.2
-
107
-
-
0036893630
-
Long-term follow-up of surgically treated gallbladder cancer patients
-
Puhalla H, Wild T, Bareck E, et al. Long-term follow-up of surgically treated gallbladder cancer patients. Eur J Surg Oncol 2002; 28: 857-63.
-
(2002)
Eur J Surg Oncol
, vol.28
, pp. 857-863
-
-
Puhalla, H.1
Wild, T.2
Bareck, E.3
-
108
-
-
0042882877
-
Results of surgical resection for patients with hilar bile duct cancer: Application of extended hepatectomy after biliary drainage and hemihepatic portal vein embolization
-
Kawasaki S, Imamura H, Kobayashi A, Noike T, Miwa S, Miyagawa S. Results of surgical resection for patients with hilar bile duct cancer: application of extended hepatectomy after biliary drainage and hemihepatic portal vein embolization. Ann Surg 2003; 238: 84-92.
-
(2003)
Ann Surg
, vol.238
, pp. 84-92
-
-
Kawasaki, S.1
Imamura, H.2
Kobayashi, A.3
Noike, T.4
Miwa, S.5
Miyagawa, S.6
-
109
-
-
0023920795
-
Long-term follow-up of patients with hilar malignant stricture treated by endoscopic internal biliary drainage
-
Deviere J, Baize M, de Toeuf J, Cremer M. Long-term follow-up of patients with hilar malignant stricture treated by endoscopic internal biliary drainage. Gastrointest Endosc 1988; 34: 95-101.
-
(1988)
Gastrointest Endosc
, vol.34
, pp. 95-101
-
-
Deviere, J.1
Baize, M.2
de Toeuf, J.3
Cremer, M.4
-
110
-
-
0026591506
-
Management of malignant hilar biliary obstruction by endoscopy. Results and prognostic factors
-
Ducreux M, Liguory C, Lefebvre JF, et al. Management of malignant hilar biliary obstruction by endoscopy. Results and prognostic factors. Dig Dis Sci 1992; 37: 778-83.
-
(1992)
Dig Dis Sci
, vol.37
, pp. 778-783
-
-
Ducreux, M.1
Liguory, C.2
Lefebvre, J.F.3
-
111
-
-
0031978913
-
Endoscopic retrograde cholangio- pancreatography and endoscopic endoprosthesis insertion in patients with Klatskin tumors
-
Liu CL, Lo CM, Lai EC, Fan ST. Endoscopic retrograde cholangio- pancreatography and endoscopic endoprosthesis insertion in patients with Klatskin tumors. Arch Surg 1998; 133: 293-6.
-
(1998)
Arch Surg
, vol.133
, pp. 293-296
-
-
Liu, C.L.1
Lo, C.M.2
Lai, E.C.3
Fan, S.T.4
-
112
-
-
0025850526
-
Palliation of proximal malignant biliary obstruction by endoscopic endoprosthesis insertion
-
Polydorou AA, Cairns SR, Dowsett JF, et al. Palliation of proximal malignant biliary obstruction by endoscopic endoprosthesis insertion. Gut 1991; 32: 685-9.
-
(1991)
Gut
, vol.32
, pp. 685-689
-
-
Polydorou, A.A.1
Cairns, S.R.2
Dowsett, J.F.3
-
113
-
-
20944448013
-
Surgical management of hilar cholangiocarcinoma
-
Hemming AW, Reed AI, Fujita S, Foley DP, Howard RJ. Surgical management of hilar cholangiocarcinoma. Ann Surg 2005; 241: 693-9.
-
(2005)
Ann Surg
, vol.241
, pp. 693-699
-
-
Hemming, A.W.1
Reed, A.I.2
Fujita, S.3
Foley, D.P.4
Howard, R.J.5
-
114
-
-
20944435837
-
Papillary phenotype confers improved survival after resection of hilar cholangiocar- cinoma
-
Jarnagin WR, Bowne W, Klimstra DS, et al. Papillary phenotype confers improved survival after resection of hilar cholangiocar- cinoma. Ann Surg 2005; 241: 703-12.
-
(2005)
Ann Surg
, vol.241
, pp. 703-712
-
-
Jarnagin, W.R.1
Bowne, W.2
Klimstra, D.S.3
-
115
-
-
0242658698
-
Successful photodynamic therapy for nonresectable cholangiocarcinoma: A randomized prospective study
-
Ortner MEJ, Caca K, Berr F, et al. Successful photodynamic therapy for nonresectable cholangiocarcinoma: a randomized prospective study. Gastroenterol 2003; 125: 1355-63.
-
(2003)
Gastroenterol
, vol.125
, pp. 1355-1363
-
-
Ortner, M.E.J.1
Caca, K.2
Berr, F.3
-
116
-
-
33644648048
-
Palliation of nonresectable bile duct cancer: Improved survival after photodynamic therapy
-
Zoepf T, Jakobs R, Arnold JC, Apel D, Riemann JF. Palliation of nonresectable bile duct cancer: improved survival after photodynamic therapy. Am J Gastroenterol 2005; 100: 2426-30.
-
(2005)
Am J Gastroenterol
, vol.100
, pp. 2426-2430
-
-
Zoepf, T.1
Jakobs, R.2
Arnold, J.C.3
Apel, D.4
Riemann, J.F.5
-
117
-
-
0036839403
-
Guidelines for the diagnosis and treatment of cholangiocarcinoma: Consensus document
-
Khan SA, Davidson BR, Goldin R, et al. Guidelines for the diagnosis and treatment of cholangiocarcinoma: consensus document. Gut 2002; 51(Suppl 6): VII-9.
-
(2002)
Gut
, vol.51
, Issue.SUPPL. 6
-
-
Khan, S.A.1
Davidson, B.R.2
Goldin, R.3
-
118
-
-
33947387077
-
Chemotherapy in advanced biliary tract carcinoma: A pooled analysis of clinical trials
-
Eckel F, Schmid RM. Chemotherapy in advanced biliary tract carcinoma: a pooled analysis of clinical trials. Br J Cancer 2007; 96: 896-902.
-
(2007)
Br J Cancer
, vol.96
, pp. 896-902
-
-
Eckel, F.1
Schmid, R.M.2
-
119
-
-
17144415942
-
Epidermal growth factor receptor dynamics influences response to epidermal growth factor receptor targeted agents
-
Jimeno A, Rubio-Viqueira B, Amador ML, et al. Epidermal growth factor receptor dynamics influences response to epidermal growth factor receptor targeted agents. Cancer Res 2005; 65: 3003-10.
-
(2005)
Cancer Res
, vol.65
, pp. 3003-3010
-
-
Jimeno, A.1
Rubio-Viqueira, B.2
Amador, M.L.3
-
120
-
-
59749091477
-
Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer
-
Tol J, Koopman M, Cats A, et al. Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer. N Engl J Med 2009; 360: 563-72.
-
(2009)
N Engl J Med
, vol.360
, pp. 563-572
-
-
Tol, J.1
Koopman, M.2
Cats, A.3
-
121
-
-
59949102930
-
A randomized phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer
-
Hecht JR, Mitchell E, Chidiac T, et al. A randomized phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer. J Clin Oncol 2009; 27: 672-80.
-
(2009)
J Clin Oncol
, vol.27
, pp. 672-680
-
-
Hecht, J.R.1
Mitchell, E.2
Chidiac, T.3
|