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Volumn 97, Issue 6, 2007, Pages 735-740

Treatment with imatinib improves drug delivery and efficacy in NSCLC xenografts

Author keywords

Drug delivery; Imatinib; Interstitial fluid pressure; Lung cancer

Indexed keywords

DOCETAXEL; DOXORUBICIN; IMATINIB;

EID: 34548580286     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6603941     Document Type: Article
Times cited : (65)

References (33)
  • 1
    • 0023736971 scopus 로고
    • UKCCCR guidelines for the welfare of animals in experimental neoplasia
    • Anon
    • Anon (1988) UKCCCR guidelines for the welfare of animals in experimental neoplasia. Br J Cancer 58: 109-113
    • (1988) Br J Cancer , vol.58 , pp. 109-113
  • 2
    • 0026786660 scopus 로고
    • Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: Implications for vascular collapse
    • Boucher Y, Jain RK (1992) Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: implications for vascular collapse. Cancer Res 52: 5110-5114
    • (1992) Cancer Res , vol.52 , pp. 5110-5114
    • Boucher, Y.1    Jain, R.K.2
  • 3
    • 0025334830 scopus 로고
    • Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: Implications for therapy
    • Boucher Y, Baxter LT, Jain RK (1990) Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: implications for therapy. Cancer Res 50: 4478-4484
    • (1990) Cancer Res , vol.50 , pp. 4478-4484
    • Boucher, Y.1    Baxter, L.T.2    Jain, R.K.3
  • 4
    • 0028968622 scopus 로고
    • Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class
    • Buchdunger E, Zimmermann J, Mett H, Meyer T, Muller M, Regenass U, Lydon NB (1995) Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class. Proc Natl Acad Sci USA 92: 2558-2562
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 2558-2562
    • Buchdunger, E.1    Zimmermann, J.2    Mett, H.3    Meyer, T.4    Muller, M.5    Regenass, U.6    Lydon, N.B.7
  • 5
    • 0022256289 scopus 로고
    • Method for determination of 4′-deoxydoxorubicin, 4′-deoxydoxorubicinol and their 7-deoxyaglycones in human serum by high-performance liquid chromatography
    • Cummings J (1985) Method for determination of 4′-deoxydoxorubicin, 4′-deoxydoxorubicinol and their 7-deoxyaglycones in human serum by high-performance liquid chromatography. J Chromatogr 341: 401-409
    • (1985) J Chromatogr , vol.341 , pp. 401-409
    • Cummings, J.1
  • 7
    • 0141645497 scopus 로고    scopus 로고
    • Targeting PDGF receptors in cancer - rationales and proof of concept clinical trials
    • George D (2003) Targeting PDGF receptors in cancer - rationales and proof of concept clinical trials. Adv Exp Med Biol 532: 141-151
    • (2003) Adv Exp Med Biol , vol.532 , pp. 141-151
    • George, D.1
  • 8
    • 0042342564 scopus 로고    scopus 로고
    • The von Hippel-Lindau protein, vascular endothelial growth factor, and kidney cancer
    • George DJ, Kaelin Jr WG (2003) The von Hippel-Lindau protein, vascular endothelial growth factor, and kidney cancer. N Engl J Med 349: 419-421
    • (2003) N Engl J Med , vol.349 , pp. 419-421
    • George, D.J.1    Kaelin Jr, W.G.2
  • 9
    • 0033178578 scopus 로고    scopus 로고
    • Taxane-induced apoptosis decompresses blood vessels and lowers interstitial fluid pressure in solid tumors: Clinical implications
    • Griffon-Etienne G, Boucher Y, Brekken C, Suit HD, Jain RK (1999) Taxane-induced apoptosis decompresses blood vessels and lowers interstitial fluid pressure in solid tumors: clinical implications. Cancer Res 59: 3776-3782
    • (1999) Cancer Res , vol.59 , pp. 3776-3782
    • Griffon-Etienne, G.1    Boucher, Y.2    Brekken, C.3    Suit, H.D.4    Jain, R.K.5
  • 10
    • 4944266313 scopus 로고    scopus 로고
    • High interstitial fluid pressure - an obstacle in cancer therapy
    • Heldin CH, Rubin K, Pietras K, Ostman A (2004) High interstitial fluid pressure - an obstacle in cancer therapy. Nat Rev Cancer 4: 806-813
    • (2004) Nat Rev Cancer , vol.4 , pp. 806-813
    • Heldin, C.H.1    Rubin, K.2    Pietras, K.3    Ostman, A.4
  • 12
    • 0030198988 scopus 로고    scopus 로고
    • 1995 Whitaker Lecture: Delivery of molecules, particles, and cells to solid tumors
    • Jain RK (1996) 1995 Whitaker Lecture: delivery of molecules, particles, and cells to solid tumors. Ann Biomed Eng 24: 457-473
    • (1996) Ann Biomed Eng , vol.24 , pp. 457-473
    • Jain, R.K.1
  • 13
    • 0035291243 scopus 로고    scopus 로고
    • Delivery of molecular and cellular medicine to solid tumors
    • Jain RK (2001) Delivery of molecular and cellular medicine to solid tumors. Adv Drug Deliv Rev 46: 149-168
    • (2001) Adv Drug Deliv Rev , vol.46 , pp. 149-168
    • Jain, R.K.1
  • 14
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
    • Jain RK (2005) Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 307: 58-62
    • (2005) Science , vol.307 , pp. 58-62
    • Jain, R.K.1
  • 15
    • 0024232289 scopus 로고
    • Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: Significance of elevated interstitial pressure
    • Jain RK, Baxter LT (1988) Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: significance of elevated interstitial pressure. Cancer Res 48: 7022-7032
    • (1988) Cancer Res , vol.48 , pp. 7022-7032
    • Jain, R.K.1    Baxter, L.T.2
  • 16
    • 0030725954 scopus 로고    scopus 로고
    • Expression in lung carcinomas of platelet-derived growth factor and its receptors
    • Kawai T, Hiroi S, Torikata C (1997) Expression in lung carcinomas of platelet-derived growth factor and its receptors. Lab Invest 77: 431-436
    • (1997) Lab Invest , vol.77 , pp. 431-436
    • Kawai, T.1    Hiroi, S.2    Torikata, C.3
  • 17
    • 3042523539 scopus 로고    scopus 로고
    • Simultaneous blockade of platelet-derived growth factor-receptor and epidermal growth factor-receptor signaling and systemic administration of paclitaxel as therapy for human prostate cancer metastasis in bone of nude mice
    • Kim SJ, Uehara H, Yazici S, Langley RR, He J, Tsan R, Fan D, Killion JJ, Fidler IJ (2004) Simultaneous blockade of platelet-derived growth factor-receptor and epidermal growth factor-receptor signaling and systemic administration of paclitaxel as therapy for human prostate cancer metastasis in bone of nude mice. Cancer Res 64: 4201-4208
    • (2004) Cancer Res , vol.64 , pp. 4201-4208
    • Kim, S.J.1    Uehara, H.2    Yazici, S.3    Langley, R.R.4    He, J.5    Tsan, R.6    Fan, D.7    Killion, J.J.8    Fidler, I.J.9
  • 18
    • 0034671219 scopus 로고    scopus 로고
    • Efficacy of liposomes and hyperthermia in a human tumor xenograft model: Importance of triggered drug release
    • Kong G, Anyarambhatla G, Petros WP, Braun RD, Colvin OM, Needham D, Dewhirst MW (2000) Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release. Cancer Res 60: 6950-6957
    • (2000) Cancer Res , vol.60 , pp. 6950-6957
    • Kong, G.1    Anyarambhatla, G.2    Petros, W.P.3    Braun, R.D.4    Colvin, O.M.5    Needham, D.6    Dewhirst, M.W.7
  • 19
    • 0842311601 scopus 로고    scopus 로고
    • Imatinib mesylate (Gleevec) inhibits ovarian cancer cell growth through a mechanism dependent on platelet-derived growth factor receptor alpha and Akt inactivation
    • Matei D, Chang DD, Jeng MH (2004) Imatinib mesylate (Gleevec) inhibits ovarian cancer cell growth through a mechanism dependent on platelet-derived growth factor receptor alpha and Akt inactivation. Clin Cancer Res 10: 681-690
    • (2004) Clin Cancer Res , vol.10 , pp. 681-690
    • Matei, D.1    Chang, D.D.2    Jeng, M.H.3
  • 21
    • 2942670180 scopus 로고    scopus 로고
    • PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma
    • Ostman A (2004) PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma. Cytokine Growth Factor Rev 15: 275-286
    • (2004) Cytokine Growth Factor Rev , vol.15 , pp. 275-286
    • Ostman, A.1
  • 22
    • 0035297541 scopus 로고    scopus 로고
    • Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors
    • Pietras K, Ostman A, Sjoquist M, Buchdunger E, Reed RK, Heldin CH, Rubin K (2001) Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors. Cancer Res 61: 2929-2934
    • (2001) Cancer Res , vol.61 , pp. 2929-2934
    • Pietras, K.1    Ostman, A.2    Sjoquist, M.3    Buchdunger, E.4    Reed, R.K.5    Heldin, C.H.6    Rubin, K.7
  • 25
    • 2542628099 scopus 로고    scopus 로고
    • Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors
    • Tong RT, Boucher Y, Kozin SV, Winkler F, Hicklin DJ, Jain RK (2004) Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors. Cancer Res 64: 3731-3736
    • (2004) Cancer Res , vol.64 , pp. 3731-3736
    • Tong, R.T.1    Boucher, Y.2    Kozin, S.V.3    Winkler, F.4    Hicklin, D.J.5    Jain, R.K.6
  • 28
    • 33750209783 scopus 로고    scopus 로고
    • Treatment with Imatinib in NSCLC is associated with decrease of phosphorylated PDGFR-beta and VEGF expression, decrease in interstitial fluid pressure and improvement of oxygenation
    • Vlahovic G, Rabbani ZN, Herndon II JE, Dewhirst MW, Vujaskovic Z (2006) Treatment with Imatinib in NSCLC is associated with decrease of phosphorylated PDGFR-beta and VEGF expression, decrease in interstitial fluid pressure and improvement of oxygenation. Br J Cancer 95: 1013-1019
    • (2006) Br J Cancer , vol.95 , pp. 1013-1019
    • Vlahovic, G.1    Rabbani, Z.N.2    Herndon II, J.E.3    Dewhirst, M.W.4    Vujaskovic, Z.5
  • 31
    • 0031903379 scopus 로고    scopus 로고
    • Transvascular drug delivery in solid tumors
    • Yuan F (1998) Transvascular drug delivery in solid tumors. Semin Radiat Oncol 8: 164-175
    • (1998) Semin Radiat Oncol , vol.8 , pp. 164-175
    • Yuan, F.1
  • 33
    • 0028304405 scopus 로고
    • Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft
    • Yuan F, Leunig M, Huang SK, Berk DA, Papahadjopoulos D, Jain RK (1994) Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft. Cancer Res 54: 3352-3356
    • (1994) Cancer Res , vol.54 , pp. 3352-3356
    • Yuan, F.1    Leunig, M.2    Huang, S.K.3    Berk, D.A.4    Papahadjopoulos, D.5    Jain, R.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.