Novel thiophenes, thienopyrimidines, and triazolothienopyrimidines for the evaluation of anticancer and augmentation effects of γ-radiation

Archiv der Pharmazie

Volumn 343, Issue 7, 2010, Pages 404-410

  Shaaban, Mohamed A ^a   Ghorab, Mostafa M ^b   Heiba, Helmy I ^b   Kamel, Mona M ^a   Zaher, Nashwa H ^b   Mostafa, Mohamed I ^c  

^a CAIRO UNIVERSITY   (Egypt)

^b HOT LABORATORIES CENTER   (Egypt)

^c KING FAISAL UNIVERSITY   (Saudi Arabia)

Author keywords

Anticancer effect and radiation; Thienopyrimidine; Thiophene; Triazolothienopyrimidine

Indexed keywords

10 METHYL 2,4,6 TRIHYDRO 3 OXOTHIENO[2,3 D]PYRIMIDO [3,4 B]TRIAZINE 9 CARBOXYLIC ACID ETHYL ESTER; 2 (9 METHYL 2,3 DIHYDROIMIDAZO[1,2 C]THIENO[3,2 E]PYRIMIDIN 8 YL) 4,5 DIHYDRO 1H IMIDAZOLE 1 CARBALDEHYDE; 2 CYANOMETHYL 9 METHYLTHIENO[3,2 E][1,2,4]TRIAZOLO [1,5 C]PYRIMIDINE 8 CARBOXYLIC ACID ETHYL ESTER 8; 2,4 BIS(4,5 DIHYDRO IMIDAZOL 2 YL) 5 AMINO 3 METHYLTHIOPHENE; 2,9 DIMETHYLTHIENO[3,2 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE 8 CARBOXYLIC ACID ETHYL ESTER; 3 AMINO 4 IMINO 5 METHYL 3,4 DIHYDROTHIENO[2,3 D]PYRIMIDINE 6 CARBOXYLIC ACID ETHYL ESTER; 4 CYANO 5 ETHOXYMETHYLENEIMINO 3 METHYLTHIOPHENE 2 CARBOXYLIC ACID ETHYL ESTER; 4 IMINO 5 METHYL 3 (3 ETHYLTHIOUREIDO)THIENO[2,3 D]PYRIMIDINE 6 CARBOXYLIC ACID ETHYL ESTER 5; 4 IMINO 5 METHYL 3 (3 PHENYLTHIOUREIDO)THIENO[2,3 D]PYRIMIDINE 6 CARBOXYLIC ACID ETHYL ESTER; 8 (4,5 DIHYDRO 1H IMIDAZOL 2 YL) 5,9 DIMETHYL 2,3 DIHYDROIMIDAZO[1,2 C]THIENO[3,2 E]PYRIMIDINE; 9 METHYL 2 PHENYLTHIENO[3,2 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE 8 CARBOXYLIC ACID ETHYL ESTER; 9 METHYLTHIENO[3,2 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE 2,8 DICARBOXYLIC ACID ETHYL ESTER; DOXORUBICIN; ETHYL 8 AMINO 9 CYANO 1 METHYLPYRAZOLO[1,5 C]THIENO[3,2 E]PYRIMIDINE 2 CARBOXYLATE; PYRIMIDINE DERIVATIVE; THIENO[2,3 D]PYRIMIDINE DERIVATIVE; THIOPHENE DERIVATIVE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; THIENOPYRIMIDINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; GAMMA RADIATION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LIVER CELL CARCINOMA; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; DRUG SCREENING; FEMALE; IC50; RADIATION RESPONSE; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DOXORUBICIN; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; GAMMA RAYS; HUMANS; INHIBITORY CONCENTRATION 50; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES;

EID: 77954604208     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200900150     Document Type: Article

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