Synthesis of new pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines and related heterocycles

Tetrahedron

Volumn 60, Issue 23, 2004, Pages 5093-5104

  Baraldi, Pier Giovanni ^a   El Kashef, Hussein ^b   Farghaly, Abdel Rahman ^b   Vanelle, Patrice ^c   Fruttarolo, Francesca ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b Assiut University   (Egypt)

^c CNRS   (France)

Author keywords

5 Amino 4 imino 1(2) substituted 1(2)H pyrazolo 3,4 d pyrimidines; Adenosine antagonists; Pyrazolo 4,3 e 1,2,4 triazolo 1, 5 c pyrimidines; Reactivity studies

Indexed keywords

(7 PHENYL 7H PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDIN 2 YLTHIO)MALONONITRILE; 1 (7 PHENYL 7H PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDIN 2 YL)THIOPROPANONE; 2 (7 PHENYL 7H PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDIN 2 YL)THIOACETAMIDE; 2 (7 PHENYL 7H PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDIN 2 YL)THIOACETIC ACID; 2 (7 PHENYL 7H PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDIN 2 YL)THIOACETONITRILE; 2 (7 PHENYL 7H PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDIN 2 YL)THIOETHYL ACETATE; 2 ETHYLTHIO 7 PHENYL 7H PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; 2 METHYL 7 PHENYL 7H PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; 2 METHYLTHIO 7 PHENYL 7H PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; 2 PHENYLAMINO 7 PHENYL 7H PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; 2,7 DIPHENYL 7H PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; 3 (BENZYLAMINOMETHYL) 7 PHENYL 7H 2,3 DIHYDRO 2 THIOXOPYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; 3 (MORPHOLIN 4 YLMETHYL) 7 PHENYL 7H 2,3 DIHYDRO 2 THIOXOPYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; 3 (PHENYLAMINOMETHYL) 7 PHENYL 7H 2,3 DIHYDRO 2 THIOXOPYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; 4 (ACETYLIMINO) 5 DIACETYLAMINO 1 PHENYL 1H PYRAZOLO[3,4 D]PYRIMIDINE; 5 AMINO 4 IMINO 1 (2 PHENYLETHYL) 1H 4,5 DIHYDROPYRANOZOLO[3,4 D]PYRIMIDINE; 5 AMINO 4 IMINO 1 PHENYL 1H 4,5 DIHYDROPYRAZOLO[3,4 D]PYRIMIDINE; 5 AMINO 4 IMINO 2 METHYL 2H 4,5 DIHYDROPYRAZOLO[3,4 D]PYRIMIDINE; 5 FORMYLAMINO 4 IMINO 1 PHENYL 1H 4,5 DIHYDROPYRAZOLO[3,4 D]PYRIMIDINE; 7 (2 PHENYLETHYL) 7H 2 OXO 2,3 DIHYDROPYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; 7 PHENYL 7H 2 OXO 2,3 DIHYDROPYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; 7 PHENYL 7H PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; ETHYL (1 PHENYL 1H PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDIN 5 YL)CARBOXYLATE; ETHYL 2 (7 PHENYL 7H PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDIN 2 YL)THIOFORMATE; ETHYL N (4 IMINO 1 PHENYL 1H 4,5 DIHYDROPYRAZOLO[3,4 D]PYRIMIDIN 5 YL)CARBAMOYL FORMATE; N (4 IMINO 1 PHENYL 1H 4,5 DIHYDROPYRANOZOLO[3,4 D]PYRIMIDIN 3 YL) 2 CHLOROACETAMIDE; N (4 IMINO 1 PHENYL 1H 4,5 DIHYDROPYRAZOLO[3,4 D]PYRIMIDIN 5 YL)BENZAMIDE; N (4 TOLYL) 2 (7 PHENYL 7H PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDIN 2 YL)THIOACETAMIDE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; DRUG SYNTHESIS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SUBSTITUTION LINE;

EID: 2442596059     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2004.04.010     Document Type: Article

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