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Volumn 41, Issue 6, 2004, Pages 941-946

Synthesis of classical and nonclassical 2-amino-4-oxo-6-benzylthieno-[2,3- d]pyrimidines as potential thymidylate synthase inhibitors

(3) Gangjee, Aleem a Qiu, Yibin a Kisliuk, Roy L b

a DUQUESNE UNIVERSITY (United States)

b TUFTS UNIVERSITY SCHOOL OF MEDICINE (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 4 OXO 6 (2' CHLOROBENZYL)THIENO[2,3 D]PYRIMIDINE; 2 AMINO 4 OXO 6 (2' METHOXYBENZYL)THIENO[2,3 D]PYRIMIDINE; 2 AMINO 4 OXO 6 (2' METHYLBENZYL)THIENO[2,3 D]PYRIMIDINE; 2 AMINO 4 OXO 6 (2',4' DICHLOROBENZYL)THIENO[2,3 D]PYRIMIDINE; 2 AMINO 4 OXO 6 (2',4' DIMETHOXYBENZYL)THIENO[2,3 D]PYRIMIDINE; 2 AMINO 4 OXO 6 (2',4' DIMETHYLBENZYL)THIENO[2,3 D]PYRIMIDINE; 2 AMINO 4 OXO 6 BENZYLTHIENO[2,3 D]PYRIMIDINE; 4 (2 AMINO 4 OXO 3,4 DIHYDROTHIENO[2,3 D]PYRIMIDIN 6 YLMETHYL)BENZOIC ACID; ALLYL ALCOHOL; ANTINEOPLASTIC AGENT; CHLOROFORMAMIDINE HYDROCHLORIDE; DIETHYL 2 [4 (2 AMINO 4 OXO 3,4 DIHYDROTHIENO[2,3 D]PYRIMIDIN 6 YLMETHYL)BENZOYL]GLUTAMATE; FORMAMIDINE; IODOBENZENE; N [4 (2 AMINO 4 OXO 3,4 DIHYDROTHIENO[2,3 D]PYRIMIDIN 6 YLMETHYL)BENZOYL]GLUTAMIC ACID; PYRIMIDINE DERIVATIVE; THYMIDYLATE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CYCLIZATION; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; HECK REACTION; IC 50; STRUCTURE ANALYSIS;

EID: 12144280397 PISSN: 0022152X EISSN: None Source Type: Journal
DOI: 10.1002/jhet.5570410613 Document Type: Article

Times cited : (28)

References (14)

1
- 0029036377
- C.W. Carreras and D. V. Santi, Annu. Rev. Biochem., 64, 721 (1995).
- (1995) Annu. Rev. Biochem. , vol.64 , pp. 721
- Carreras, C.W.¹ Santi, D.V.²

2
- 0001873818
- K. T. Douglas, Med. Res. Rev., 7, 441 (1987).
- (1987) Med. Res. Rev. , vol.7 , pp. 441
- Douglas, K.T.¹

3
- 0025970198
- E. M. Berman and L. M. Werbel, J. Med. Chem., 34, 479 (1991).
- (1991) J. Med. Chem. , vol.34 , pp. 479
- Berman, E.M.¹ Werbel, L.M.²

4
- 0001181244
- A. Gangjee, E. Elzein, M. Kothare and A. Vasudevan, Curr. Pharm. Design., 2, 263 (1996).
- (1996) Curr. Pharm. Design , vol.2 , pp. 263
- Gangjee, A.¹ Elzein, E.² Kothare, M.³ Vasudevan, A.⁴

5
- 0019368721
- T. R. Jones, A. H. Calvert, A. L. Jackman, S. J. Brown, M. Jones and K. R. Harrap, Eur. J. Cancer., 17, 11 (1981).
- (1981) Eur. J. Cancer , vol.17 , pp. 11
- Jones, T.R.¹ Calvert, A.H.² Jackman, A.L.³ Brown, S.J.⁴ Jones, M.⁵ Harrap, K.R.⁶

6
- 0025997350
- A. L. Jackman, G. A. Taylor, W. Gibson, R. Kimbell, M. Brown, A. H. Calvert, I. R. Judson and L. R. Hughes, Cancer Res., 51, 5579 (1991).
- (1991) Cancer Res. , vol.51 , pp. 5579
- Jackman, A.L.¹ Taylor, G.A.² Gibson, W.³ Kimbell, R.⁴ Brown, M.⁵ Calvert, A.H.⁶ Judson, I.R.⁷ Hughes, L.R.⁸

7
- 0026494947
- E. C. Taylor, D. Kuhnt, C. Shih, S. M. Rinzel, G. B. Grindey, J. Barredo, M. Jannatipour, and R. G. Moran, J. Med. Chem., 35, 4450 (1992).
- (1992) J. Med. Chem. , vol.35 , pp. 4450
- Taylor, E.C.¹ Kuhnt, D.² Shih, C.³ Rinzel, S.M.⁴ Grindey, G.B.⁵ Barredo, J.⁶ Jannatipour, M.⁷ Moran, R.G.⁸

8
- 2942618206
- R. Zhao and I. D. Goldman, The Oncologist, 9, 242-244 (2004).
- (2004) The Oncologist , vol.9 , pp. 242-244
- Zhao, R.¹ Goldman, I.D.²

9
- 0027403420
- S. E. Webber, T. M. Bleckman, J. Attard, J. G. Deal, V. Katherdekar, K. M. Welsh, S. Webber, C. A. Janson, D. A. Matthews, W. W. Smith, S. T. Freer, S. R. Jordan, R. J. Bacquet, E. F. Howland, C. L. J. Booth, R. W. Ward, S. M. Hermann, J. White, C. A. Morse, J. A. Hilliard, C. A. Bartlett, J. Med. Chem., 36, 733 (1993).
- (1993) J. Med. Chem. , vol.36 , pp. 733
- Webber, S.E.¹ Bleckman, T.M.² Attard, J.³ Deal, J.G.⁴ Katherdekar, V.⁵ Welsh, K.M.⁶ Webber, S.⁷ Janson, C.A.⁸ Matthews, D.A.⁹ Smith, W.W.¹⁰ Freer, S.T.¹¹ Jordan, S.R.¹² Bacquet, R.J.¹³ Howland, E.F.¹⁴ Booth, C.L.J.¹⁵ Ward, R.W.¹⁶ Hermann, S.M.¹⁷ White, J.¹⁸ Morse, C.A.¹⁹ Hilliard, J.A.²⁰ Bartlett, C.A.²¹ more..

10
- 0029072232
- A. Gangjee, F. Mavandadi, J. J. McGuire, J. Med. Chem., 38, 2158 (1995).
- (1995) J. Med. Chem. , vol.38 , pp. 2158
- Gangjee, A.¹ Mavandadi, F.² McGuire, J.J.³

11
- 0035821589
- A. Gangjee, A. Vidwans, E. Elzein, J. J. McGuire, S. F. Queener, R. L. Kisliuk, J. Med. Chem., 44, 1993 (2001).
- (2001) J. Med. Chem. , vol.44 , pp. 1993
- Gangjee, A.¹ Vidwans, A.² Elzein, E.³ McGuire, J.J.⁴ Queener, S.F.⁵ Kisliuk, R.L.⁶

12
- 0034781144
- H. Zhao, M. Cai, R. Hu, C. Song, Synthetic Communications, 31, 3665 (2001).
- (2001) Synthetic Communications , vol.31 , pp. 3665
- Zhao, H.¹ Cai, M.² Hu, R.³ Song, C.⁴

13
- 12144260881
- EP 0261503 (1988)
- F. Bonifacio, M. Fano, L. Trabella, G. Battigelli, D. Montagna, V. Bernareggi, EP 0261503 (1988); Chem. Abstr., 109, 128819 (1988).
- (1988) Chem. Abstr. , vol.109 , pp. 128819
- Bonifacio, F.¹ Fano, M.² Trabella, L.³ Battigelli, G.⁴ Montagna, D.⁵ Bernareggi, V.⁶

14
- 0028822043
- A. Gangjee, R. Devraj, J. J. McGuire, R. L. Kisliuk, J. Med. Chem., 38, 4495 (1995).
- (1995) J. Med. Chem. , vol.38 , pp. 4495
- Gangjee, A.¹ Devraj, R.² McGuire, J.J.³ Kisliuk, R.L.⁴

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