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Molecular BioSystems

Volumn 6, Issue 8, 2010, Pages 1463-1468

Genetic approach to evaluate specificity of small molecule drug candidates inhibiting PLK1 using zebrafish

(8) Zhong, Hanbing a Xin, Shengchang a Zhao, Yanqiu a Lu, Jing a Li, Song a Gong, Jianxian a Yang, Zhen a Lin, Shuo a,b

a Shenzhen University Town (China)

b UNIVERSITY OF CALIFORNIA (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; ONCOPROTEIN; POLO LIKE KINASE 1; POLO-LIKE KINASE 1; PROTEIN KINASE INHIBITOR; PROTEIN SERINE THREONINE KINASE;

ANIMAL; ANIMAL EMBRYO; ARTICLE; BIOLOGICAL MODEL; COMBINATORIAL CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; EMBRYO DEVELOPMENT; ENZYME SPECIFICITY; EVALUATION; GENETIC PROCEDURES; GENETICS; METABOLISM; METHODOLOGY; MOLECULAR LIBRARY; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRENATAL DEVELOPMENT; ZEBRA FISH;

ANIMALS; CELL CYCLE PROTEINS; COMBINATORIAL CHEMISTRY TECHNIQUES; CONSERVED SEQUENCE; DRUG EVALUATION, PRECLINICAL; EMBRYO, NONMAMMALIAN; EMBRYONIC DEVELOPMENT; GENETIC TECHNIQUES; MODELS, BIOLOGICAL; PHYLOGENY; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; SMALL MOLECULE LIBRARIES; SUBSTRATE SPECIFICITY; ZEBRAFISH;

DANIO RERIO;

EID: 77954600984 PISSN: 1742206X EISSN: 17422051 Source Type: Journal
DOI: 10.1039/b919743e Document Type: Article

Times cited : (8)

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