Robustness under functional constraint: The genetic network for temporal expression in Drosophila neurogenesis

PLoS Computational Biology

Volumn 6, Issue 4, 2010, Pages

  Nakajima, Akihiko ^a   Isshiki, Takako ^b   Kaneko, Kunihiko ^a,c   Ishihara, Shuji ^a,c  

^a UNIVERSITY OF TOKYO   (Japan)

^b NATIONAL INSTITUTE OF GENETICS   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

NEURONS; STEM CELLS;

DEVELOPMENTAL BIOLOGY; DROSOPHILLA; EXPRESSION PATTERNS; EXPRESSION PROFILE; FUNCTIONAL CONSTRAINTS; GENES EXPRESSION; GENETIC NETWORKS; NEUROGENESIS; TEMPORAL COORDINATION; TEMPORAL EXPRESSIONS;

GENE EXPRESSION;

KRUPPEL LIKE FACTOR; TRANSCRIPTION FACTOR;

ARTICLE; CELL TYPE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEVELOPMENTAL BIOLOGY; DROSOPHILA; EMBRYO DEVELOPMENT; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; IN VIVO STUDY; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEUROBLAST; NONHUMAN; PREDICTION; WILD TYPE; ANIMAL; BIOLOGICAL MODEL; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; METHODOLOGY; MORPHOGENESIS; NERVE CELL; PHYSIOLOGY; PRENATAL DEVELOPMENT; REGRESSION ANALYSIS; STATISTICAL MODEL; STEM CELL; SYSTEMS BIOLOGY; TIME;

ANIMALS; BODY PATTERNING; DROSOPHILA; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; MODELS, BIOLOGICAL; MODELS, STATISTICAL; NEUROGENESIS; NEURONS; REGRESSION ANALYSIS; STEM CELLS; SYSTEMS BIOLOGY; TIME FACTORS;

EID: 77954570182     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000760     Document Type: Article

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