Cis-regulatory logic in the endo16 gene: Switching from a specification to a differentiation mode of control

Development

Volumn 128, Issue 5, 2001, Pages 617-629

  Yuh, C H ^a   Bolouri, H ^a   Davidson, E H ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Computational model; Gene regulation; Gene transfer; Sea urchin

Indexed keywords

CELL SURFACE PROTEIN; ENDO 16 PROTEIN; POLYFUNCTIONAL GROUP; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CELL SPECIFICITY; CONTROL SYSTEM; CONTROLLED STUDY; EMBRYO DEVELOPMENT; ENDODERM; GASTRULATION; GENE CONTROL; GENE EXPRESSION; GENE SWITCHING; INFORMATION PROCESSING; INTESTINE SECRETION; LARVA; LOGIC; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MESODERM; MIDGUT; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROTEIN SECRETION; SEA URCHIN; SEQUENCE ANALYSIS; STRONGYLOCENTROTUS;

NON-PROGRAMMATIC;

ANIMALS; BASE SEQUENCE; CELL ADHESION MOLECULES; DNA; EMBRYO, NONMAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, REPORTER; HOMEODOMAIN PROTEINS; IN SITU HYBRIDIZATION; KINETICS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; OTX TRANSCRIPTION FACTORS; PROMOTER REGIONS (GENETICS); PROTEINS; RECOMBINANT FUSION PROTEINS; REGULATORY SEQUENCES, NUCLEIC ACID; SEA URCHINS; TRANSCRIPTION, GENETIC;

ECHINOIDEA; INVERTEBRATA; STRONGYLOCENTROTUS PURPURATUS;

EID: 0035094449     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

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10. Two Otx proteins generated from multiple transcripts of a single gene in Strongylocentrotus purpuratus
11. Requirement of SpOtx in cell fate decisions in the sea urchin embryo and possible role as a mediator of β-catenin signaling
12. Endo16, a lineage-specific protein of the sea urchin embryo, is first expressed just prior to gastrulation
13. Whole mount in situ hybridization shows Endo-16 to be a marker for the vegetal plate territory in sea urchin embryos
14. Endo16, a large multidomain protein found on the surface and ECM of endodermal cells during sea urchin gastrulation, binds calcium
15. Modular cis-regulatory organization of Endo16, a gut-specific gene of the sea urchin embryo
16. Complexity and organization of DNA-protein interactions in the 5′ regulatory region of an endoderm-specific marker gene in the sea urchin embryo
17. Quantitative functional interrelations within the cis-regulatory system of the S. purpuratus Endo16 gene
18. Genomic cis-regulatory logic: Functional analysis and computational model of a sea urchin gene control system
19. Correct expression of specza in the sea urchin embryo requires both Otx and other cis-regulatory elements
20. SpGCF1, a sea urchin embryo transcription factor, exists as five nested variants encoded by a single mRNA
21. A multimerizing transcription factor of sea urchin embryos capable of looping DNA