Regulation of POU genes by castor and hunchback establishes layered compartments in the Drosophila CNS

Genes and Development

Volumn 12, Issue 2, 1998, Pages 246-260

  Kambadur, Ravi ^a,d   Koizumi, Keita ^a   Stivers, Chad ^a   Nagle, James ^b   Poole, Stephen J ^c   Odenwald, Ward F ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d RUAKURA RESEARCH CENTRE   (New Zealand)

Author keywords

Castor; CNS POU gene regulation; Hunchback; Zinc finger proteins

Indexed keywords

DNA; DNA BINDING PROTEIN; MESSENGER RNA; TRANSCRIPTION FACTOR; ZINC FINGER PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DROSOPHILA; EMBRYO; NERVOUS SYSTEM DEVELOPMENT; NEUROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATOR GENE; TRANSCRIPTION REGULATION;

ANIMALIA; DROSOPHILA; HEXAPODA; INSECTA;

EID: 0031985053     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.12.2.246     Document Type: Article

References (70)

1. Anderson, M.G., G.L. Perkins, P. Chittick, R.J. Shrigley, and W.A. Johnson. 1995. drifter, a Drosophila POU-domain transcription factor, is required for correct differentiation and migration of tracheal cells and midline glia. Genes & Dev. 9: 123-137.
2. Artavanis-Tsakonas, S.A., K. Matsuno, and M.E. Fortini. 1995. Notch Signaling. Science 268: 225-232.
3. Ashburner, M. 1989. Drosophila: A laboratory manual. Cold Spring Harbor Laboratory Press, Cold Sping Harbor, NY.
4. Bellefroid, E.J., D.A. Poncelet, P.J. Lecocq, O. Revelant, and J.A. Martial. 1991. The evolutionarily conserved Kruppel-associated box domain defines a subfamily of eukaryotic multifingered proteins. Proc. Natl. Acad. Sci. 88: 3608-3612.
5. Bhat, K. and P. Schedl. 1994. The Drosophila miti-mere gene, a member of the POU family, is required for the specification of the RP2/sibling lineage during neurogenesis. Development 120: 1483-1501.
6. Bhat, K., S.J. Poole, and P. Schedl. 1995. The miti-mere and pdm-1 genes collaborate during specification of the RP2/sib lineage in Drosophila neurogenesis. Mol. Cell Biol. 15: 4052-4063.
7. Bier, E. 1997. Anti-Neural-Inhibition: A conserved mechanism for neural induction. Cell 89: 681-684.
8. Billin, A.N., K.A. Cockerill, and S.J. Poole. 1991. Isolation of a family of Drosophila POU domain genes expressed in early development. Mech. Dev. 34: 75-84.
9. Bossing, T., G. Udolph, C.Q. Doe, and G.M. Technau. 1996. The embryonic central nervous system lineages of Drosophila melanogaster: 1. Neuroblast lineages derived from the ventral half of the neuroectoderm. Dev. Biol. 179: 41-64.
10. Brand, A.H. and N. Perrimon. 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401-415.
11. Broadus, J., J.B. Skeath, E.P. Spana, T. Bossing, G.M. Technau, and C.Q. Doe. 1995. New neuroblast markers and the origin of the aCC/pCC neurons in the Drosophila central nervous system. Mech. Dev. 53: 393-402.
12. Buenzow, D.E. and R. Holmgren. 1995. Expression of the Drosophila gooseberry locus defines a subset of neuroblast lineages in the central nervous system. Dev. Biol. 170: 338-349.
13. Campos-Ortega, J.A. 1993. Early neurogenesis in Drosophila melanogaster. In The development of Drosophila melanogaster (ed. M. Bate and A.M. Arias), pp. 1091-1131. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
14. Cockerill, K.A., A.N. Billin, and S.J. Poole. 1993. Regulation of expression domains and effects of ectopic expression reveal gap gene-like properties of the linked pdm genes of Drosophila. Mech. Dev. 41: 139-153.
15. Cui, X. and C.Q. Doe. 1992. ming is expressed in neuroblast sublineages and regulates gene expression in the Drosophila central nervous system. Development 116: 946-953.
16. _. 1995. The role of the cell cycle and cytokinesis in regulating neuroblast sublineage gene expression in the Drosophila CNS. Development 121: 3233-3243.
17. Dick, T., X. Yang, S. Yeo, and W. Chia. 1991. Two closely linked Drosophila POU domain genes are expressed in neuroblasts and sensory elements. Proc. Natl. Acad. Sci. 88: 7645-7649.
18. Doe, C.Q., Q. Chu-LaGraff, D.M. Wright, and M.P. Scott. 1991. The prospero gene specifies cell fates in the Drosophila central nervous system. Cell 65: 451-464.
19. Elrod-Erickson, M., M.A. Rould, L. Nekludova, and C.O. Pabo. 1996. Zif268 protein-DNA complex refined at 1.6A: A model system for understanding zinc finger-DNA interactions. Structure 4: 1171-1180.
20. Fairall, L., J.W.R. Schwabe, L. Chapman, J.T. Finch, and D. Rhodes. 1993. The crystal structure of a two zinc-finger peptide reveals an extension to the rules for zinc-finger/DNA recognition. Nature 366: 483-487.
21. Frantz, G.D., A.P. Bohner, R.M. Akers, and S.K. McConnell. 1994a. Regulation of the POU domain gene SCIP during cerebral cortical development. J. Neurosci. 14: 472-485.
22. Frantz, G.D., J.M. Weimann, M.E. Levin, and S.K. McConnell. 1994b. Otx1 and Otx2 define layers ond regions in developing cerebral cortex and cerebellum. J. Neurosci. 14: 5725-5740.
23. Goodman, C.S. and C.Q. Doe. 1993. Embryonic development of the Drosophila central nervous system. In The development of Drosophila melanogaster (ed. M. Bate and A.M. Arias), pp. 1131-1206. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
24. Harlow, E. and D. Lane. 1988. Antibodies: A laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
25. Hartenstein, V. and J.A. Campos-Ortega. 1984. Early neurogenesis in wild type Drosophila melanogaster. Wilhelm Roux's Arch. Dev. Biol. 193: 308-325.
26. Herr, W., R.A. Sturm, R.G. Clerc, L.M. Corcoran, D. Baltimore, P.A. Sharp, H.A. Ingraham, M.G. Rosenfeld, M. Finney, G. Ruvkun, and H.R. Horvitz. 1988. The POU domain: A large conserved region in the mammalian pit-1, oct-1, oct-2 and Caenorhabditis elegans unc-86 gene products. Genes & Dev. 2: 1513-1516.
27. Hiromi, Y., A. Kuroiwa, and W.J. Gehring. 1985. Control elements of the Drosophila segmentation gene fushi tarazu. Cell 43: 603-613.
28. Jan, J.N. and L.Y. Jan. 1994. Genetic control of cell fate specification in Drosophila peripheral nervous system. Annu. Rev. Genet. 28: 373-393.
29. _. 1995. Maggot's hair and bug's eye: Role of cell interactions and intrinsic factors in cell fate specification. Neuron 14: 1-5.
30. Jimenez, F. and J.A. Campos-Ortega. 1990. Defective neuroblast commitment in mutants of the achaete-scute complex and adjacent genes of D. melanogaster. Neuron 5: 81-89.
31. Johnson, W. and J. Hirsh. 1990. Binding of a Drosophila POU-domain protein to a sequence element regulating gene expression in specific dopaminergic neurons. Nature 343: 467-470.
32. Kania, M.A., A.S. Bonner, J.B. Duffy, and P.J. Gergen. 1990. The Drosophila segmentation gene runt encodes a novel nuclear regulatory protein that is also expressed in the developing nervous system. Genes & Dev. 4: 1701-1713.
33. Lin, H. and T. Schagat. 1997. Neuroblasts: A model for the asymmetric division of stem cells. Trends Genet 13: 33-39.
34. Lindsley, D.L. and G.G. Zimm. 1992. The genome of Drosophila melanogaster. Academic Press, San Diego, CA.
35. Lloyd, A. and S. Sakonju. 1991. Characterisation of two Drosophila POU domain genes, related to oct-1 and oct-2, and the regulation of their expression patterns. Mech. Dev. 36: 87-102.
36. McConnell, S.K. 1988. Development and decision-making in the mammalian cerebral cortex. Brain Res. Rev. 13: 1-23.
37. _. 1995. Constructing the cerebral cortex: Neurogenesis and fate determination. Neuron 15: 761-768.
38. Mellerick, D.M., J.A. Kassis, S.-D. Zhang, and W.F. Odenwald. 1992. castor encodes a novel Zinc finger protein required for the development of a subset of CNS neurons in Drosophila. Neuron 9: 789-803.
39. Miller, J., A.D. MacLachlan, and A. Klug. 1985. Repetitive zinc-binding domains in the protein transcription factor IIIa from Zenopus oocytes. EMBO J. 4: 1609-1614.
40. Morrison, S.J., N.M. Shah, and D.J. Anderson. 1997. Regulatory mechanisms in stem cell biology. Cell 88: 287-298.
41. Nambu, J.R., R.G. Franks, S. Hu, and S.T. Crews. 1990. The single-minded gene of Drosophila is required for the expression of genes important for the development of CNS midline cells. Cell 63: 63-75.
42. Ng, M., F.J. Diaz-Benjumea, and S.M. Cohen. 1995. Nubbin encodes a POU-domain protein required for proximal-distal patterning in the Drosophila wing. Development 121: 589-599.
43. Odenwald, W.F., J. Garbern, H. Arnheiter, E. Tournier-Lasserve, and R.A. Lazzarini. 1989. The Hox 1.3 homeobox protein is a sequence-specific DNA-binding phosphoprotein. Genes & Dev. 3: 158-172.
44. Patel, N.H. 1994. Imaging neuronal subsets and other cell types in whole-mount Drosophila embryos and larvae using antibody probes. Methods Cell Biol. 44: 445-487.
45. Pavletich, N.P. and C.O. Pabo. 1993. Crystal structure of a five-finger GLI-DNA complex: New perspectives on zinc fingers. Science 261: 1701-1707.
46. Pirrotta, V. 1988. Vectors for P-element transformation in Drosophila. In Vectors, a survey of molecular cloning vectors and their uses (ed. R.L. Rodriguez and D.T. Denhardt), pp. 437-456. Butterworths, Boston, MA.
47. Prakash, K., X.-D. Fang, D. Engelberg, A. Behal, and C.S. Parker. 1992. dOct2, a Drosophila Oct transcription factor that functions in yeast. Proc. Natl. Acad. Sci. 89: 7080-7084.
48. Prokop, A. and G.M. Technau. 1994. Early tagma-specific commitment of Drosophila CNS progenitor NB1-1. Development 120: 2567-2578.
49. Rivera-Pomar, R. and H. Jackle. 1996. From gradients to stripes in Drosophila embryogenesis: filling in the gaps. Trends Genetics 12: 478-483.
50. Roark, M., M.A. Sturtevant, J. Emery, H. Vaessin, E. Grell, and E. Bier. 1995. scratch, a pan-neural gene encoding a zinc finger protein related to snail, promotes neuronal development. Genes & Dev. 9: 2384-2398.
51. Robertson, H.M., C.R. Preston, R.W. Phillis, D.M. Johnson-Shiltz, W.K. Benz, and W.R. Engels. 1988. A stable genomic source of P-element transposase in Drosophila melanogaster. Genetics 118: 461-470.
52. Ryan, A.K. and M.G. Rosenfeld. 1997. POU domain family values: Flexibility, partnerships, and developmental codes. Genes & Dev. 11: 1207-1225.
53. Sambrook, J., E.F. Fritsch, and T. Maniatis. 1989. Molecular cloning a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
54. Sanger, F., S. Nicklen, and A.R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. 74: 54-63.
55. Savage, R.M. and M. Shankland. 1996. Identification and characterization of a hunchback orthologue, Lzf2, and its expression during Leech embryogenesis. Dev. Biol. 175: 205-217.
56. Shirakata, M., F.K. Friedman, Q. Wei, and B.M. Paterson. 1993. Dimerization specificity of myogenic helix-loop-helix DNA-binding factors directed by nonconserved hydrophilic residues. Genes & Dev. 7: 2456-2470.
57. Spradling, A.C. 1986. P element-mediated transformation. In Drosophila: A practical approach (ed. D. B. Roberts), pp. 175-197. IRL Press, Oxford, UK.
58. Stanojevic, D., T. Hoey, and M. Levine. 1989. Sequence-specific DNA-binding activities of the gap proteins encoded by hunchback and Kruppel in Drosophila. Nature 341: 331-335.
59. Struhl, G., P. Johnston, and P.A. Lawrence. 1992. Control of Drosophila body pattern by the hunchback morphogen gradient. Cell 69: 237-249.
60. Studier, F.W., A.H. Rosenberg, J.J. Dunn, and J.W. Dubendorff. 1990. Use of T7 RNA polymerase to direct expression of cloned genes. Meth. Enzymol. 185: 60-89.
61. Tautz, D. and C. Pfeifle. 1989. A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma 98: 81-85.
62. Tautz, D., R. Lehmann, H. Schnurch, R. Schuh, E. Seifert, A. Kienlin, K. Jones, and H. Jackle. 1987. Finger protein of novel structure encoded by hunchback, a second member of the gap class of Drosophila segmentation genes. Nature 327: 383-389.
63. Treacy, M.N., X. He, and M.G. Rosenfeld. 1991. I-POU: A POU domain protein that inhibits neuron-specific gene activation. Nature 350: 577-584.
64. Treisman, J. and C. Desplan. 1989. The products of the Drosophila gap genes hunchback and Kruppel bind to the hunchback promoters. Nature 341: 335-337.
65. Vaessin, H., E. Grell, E. Wolff, E. Bier, L.Y. Jan, and Y.N. Jan. 1991. Prospero is expressed in neuronal precursors and encodes a nuclear protein that is involved in the control of axonal outgrowth in Drosophila. Cell 67: 941-953.
66. Weigmann, K. and C.F. Lehner. 1995. Cell fate specification by even-skipped expression in the Drosophila nervous system is coupled to cell cycle progression. Development 121: 3713-3721.
67. White, R.A.H. and R. Lehmann. 1986. A gap gene, hunchback, regulates the spatial expression of Ultrabithorax. Cell 47: 311-321.
68. Wright W.E., M. Binder, and W. Funk. 1991. Cyclic amplification and selection of targets (CASTing) for the myogenin consensus binding site. Mol. Cell. Biol. 11: 4104-4110.
69. Yang, X., S. Yeo, T. Dick, and W. Chia. 1993. The role of a Drosophila POU homeo domain gene in the specification of neural precursor cell identity in the developing embryonic central nervous system. Genes & Dev. 7: 504-516.
70. Yeo, S.L., A. Lloyd, K. Kozak, A. Dinh, T. Dick, X. Yang, S. Sakonju, and W. Chia. 1995. On the functional overlap between two Drosophila POU homeo domain genes and the cell fate specification of a CNS neural precursor. Genes & Dev. 9: 1223-1236.