Sevoflurane postconditioning prevents activation of caspase 3 and 9 through antiapoptotic signaling after myocardial ischemia-reperfusion

Journal of Anesthesia

Volumn 24, Issue 2, 2010, Pages 215-224

  Inamura, Yoshitaka ^a   Miyamae, Masami ^a   Sugioka, Shingo ^a   Domae, Naochika ^a   Kotani, Junichiro ^a  

^a OSAKA DENTAL UNIVERSITY   (Japan)

Author keywords

Akt; Caspase; ERK; Postconditioning; Sevoflurane

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; CASPASE 3; CASPASE 9; MITOGEN ACTIVATED PROTEIN KINASE; PENTOBARBITAL; PROTEIN KINASE B; SEVOFLURANE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; GUINEA PIG; HEART INFARCTION SIZE; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; ISOLATED HEART; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REPERFUSION INJURY; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANESTHETICS, INHALATION; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CASPASE 9; CHROMONES; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; GUINEA PIGS; HEMODYNAMICS; IMMUNOHISTOCHEMISTRY; MALE; METHYL ETHERS; MORPHOLINES; MYOCARDIUM; PROTO-ONCOGENE PROTEINS C-AKT; REPERFUSION INJURY;

EID: 77954534711     PISSN: 09138668     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00540-010-0877-6     Document Type: Article

References (40)

1. Stadnicka A, Marinovic J, Ljubkovic M, Bienengraeber MW, Bosnjak ZJ. Volatile anesthetic-induced cardiac preconditioning. J Anesth. 2007;21:212-219
2. Tanaka K, Ludwig LM, Kersten JR, Pagel PS, Warltier DC. Mechanisms of cardioprotection by volatile anesthetics. Anesthesiology. 2004;100:707-721
3. Wakeno-Takahashi M, Otani H, Nakao S, Uchiyama Y, Imamura H, Shingu K. Adenosine and a nitric oxide donor enhances cardioprotection by preconditioning with isoflurane through mitochondrial adenosine triphosphate-sensitive K? channeldependent and -independent mechanisms. Anesthesiology. 2004;100:515-524
4. Kaneda K, Miyamae M, Sugioka S, Okusa C, Inamura Y, Domae N, Kotani J, Figueredo VM. Sevoflurane enhances ethanolinduced cardiac preconditioning through modulation of protein kinase C, mitochondrial KATP channels, and nitric oxide synthase, in guinea pig hearts. Anesth Analg. 2008;106:9-16.
5. Okusa C, Miyamae M, Sugioka S, Kaneda K, Inamura Y, Onishi A, Domae N, Kotani J, Figueredo VM. Acute memory phase of sevoflurane preconditioning is associated with sustained translocation of protein kinase C-a and e, but not d, in isolated guinea pig hearts. Eur J Anaesthesiol. 2009;26:582-588
6. Inamura Y, Miyamae M, Sugioka S, Kaneda K, Okusa C, Onishi A, Domae N, Kotani J, Figueredo VM. Aprotinin abolishes sevoflurane postconditioning by inhibiting nitric oxide production and phosphorylation of protein kinase C-d and glycogen synthase kinase 3b. Anesthesiology. 2009;111(5):1036-1043
7. Pagel PS. Postconditioning by volatile anesthetics: salvaging ischemic myocardium at reperfusion by activation of prosurvival signaling. J Cardiothorac Vasc Anesth. 2008;22:753-765
8. Zhao ZQ, Velez DA, Wang NP, Hewan-Lowe KO, Nakamura M, Guyton RA, Vinten-Johansen J. Progressively developed myocardial apoptotic cell death during late phase of reperfusion. Apoptosis. 2001;6:279-290
9. Zidar N, Dolenc-Strazar Z, Jeruc J, Stajer D. Immunohistochemical expression of activated caspase-3 in human myocardial infarction. Virchows Arch. 2006;448:75-79
10. Hausenloy DJ, Yellon DM. New directions for protecting the heart against ischaemia-reperfusion injury: targeting the reperfusion injury salvage kinase (RISK)-pathway. Cardiovasc Res. 2004;61:448-460
11. Tsang A, Hausenloy DJ, Mocanu MM, Yellon DM. Postconditioning: a form of "modified reperfusion" protects the myocardium by activating the phosphatidylinositol 3-kinase-Akt pathway. Circ Res. 2004;95:230-232
12. Li H, Wang JK, Zeng YM, Yang CX, Chen HT, Wen XJ, Shui CL, Liang H. Sevoflurane post-conditioning protects against myocardial reperfusion injury by activation of phosphatidylinositol- 3-kinase signal transduction. Clin Exp Pharmacol Physiol. 2008;35:1043-1051
13. Penna C, Perrelli MG, Raimondo S, Tullio F, Merlino A, Moro F, Geuna S, Mancardi D, Pagliaro P. Postconditioning induces an anti-apoptotic effect and preserves mitochondrial integrity in isolated rat hearts. Biochim Biophys Acta. 2009;1787:794-801.
14. Takatani T, Takahashi K, Uozumi Y, Matsuda T, Ito T, Schaffer SW, Fujio Y, Azuma J. Taurine prevents the ischemia-induced apoptosis in cultured neonatal rat cardiomyocytes through Akt/ caspase-9 pathway. Biochem Biophys Res Commun. 2004;316:484-489
15. Chen HT, Yang CX, Li H, Zhang CJ, Wen XJ, Zhou J, Fan YL, Huang T, Zeng YM. Cardioprotection of sevoflurane postconditioning by activating extracellular signal-regulated kinase 1/2 in isolated rat hearts. Acta Pharmacol Sin. 2008;29:931-941
16. Li DY, Tao L, Liu H, Christopher TA, Lopez BL, Ma XL. Role of ERK1/2 in the anti-apoptotic and cardioprotective effects of nitric oxide after myocardial ischemia and reperfusion. Apoptosis. 2006;11:923-930
17. Fujio Y, Nguyen T, Wencker D, Kitsis RN, Walsh K. Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart. Circulation. 2000;101:660-667
18. Matsui T, Tao J, del Monte F, Lee KH, Li L, Picard M, Force TL, Franke TF, Hajjar RJ, Rosenzweig A. Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo. Circulation. 2001;104:330-335
19. Hengartner MO. The biochemistry of apoptosis. Nature. 2000;407:770-776
20. FishbeinMC,MeerbaumS, Rit J, Lando U, Kanmatsuse K,Mercier JC, Corday E, Ganz W. Early phase acute myocardial infarct size quantification: validation of the triphenyl tetrazoliumchloride tissue enzyme staining technique. Am Heart J. 1981;101:593-600.
21. Obal D, Scharbatke H, Barthel H, Preckel B, Müllenheim J, Schlack W. Cardioprotection against reperfusion injury is maximal with only two minutes of sevoflurane administration in rats. Can J Anaesth. 2003;50:940-945
22. Saraste A, Pulkki K, Kallajoki M, Henriksen K, Parvinen M, Voipio-Pulkki LM. Apoptosis in human acute myocardial infarction. Circulation. 1997;95:320-323
23. Jugdutt BI, Idikio HA. Apoptosis and oncosis in acute coronary syndromes: assessment and implications. Mol Cell Biochem. 2005;270:177-200.
24. Gown AM, Willingham MC. Improved detection of apoptotic cells in archival paraffin sections: immunohistochemistry using antibodies to cleaved caspase 3. J Histochem Cytochem. 2002;50:449-454
25. Freude B, Masters TN, Robicsek F, Fokin A, Kostin S, Zimmermann R, Ullmann C, Lorenz-Meyer S, Schaper J. Apoptosis is initiated by myocardial ischemia and executed during reperfusion. J Mol Cell Cardiol. 2000;32:197-208.
26. Gottlieb RA, Burleson KO, Kloner RA, Babior BM, Engler RL. Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J Clin Invest. 1994;94:1621-1628
27. Armstrong SC. Protein kinase activation and myocardial ischemia/ reperfusion injury. Cardiovasc Res. 2004;61:427-436
28. Uchiyama T, Engelman RM, Maulik N, Das DK. Role of Akt signaling in mitochondrial survival pathway triggered by hypoxic preconditioning. Circulation. 2004;109:3042-3049
29. Murphy E. Primary and secondary signaling pathways in early preconditioning that converge on the mitochondria to produce cardioprotection. Circ Res. 2004;94:7-16.
30. Raphael J, Rivo J, Gozal Y. Isoflurane-induced myocardial preconditioning is dependent on phosphatidylinositol-3-kinase/Akt signalling. Br J Anaesth. 2005;95:756-763
31. Wang C, Weihrauch D, Schwabe DA, Bienengraeber M, Warltier DC, Kersten JR, Pratt PF, Jr., Pagel PS. Extracellular signalregulated kinases trigger isoflurane preconditioning concomitant with upregulation of hypoxia-inducible factor-1alpha and vascular endothelial growth factor expression in rats. Anesth Analg. 2006;103:281-288 (table of contents).
32. Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, Nagata S. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature. 1998;391: 43-50.
33. Imamura G, Bertelli AA, Bertelli A, Otani H, Maulik N, Das DK. Pharmacological preconditioning with resveratrol: an insight with iNOS knockout mice. Am J Physiol Heart Circ Physiol. 2002;282:H1996-2003.
34. Loucks EB, Godin DV, Walley KR, McManus BM, Rahimian R, Granville DJ, Hong JM, Aktary FM, Qayumi AK. Role of platelet activating factor in cardiac dysfunction, apoptosis and nitric oxide synthase mRNA expression in the ischemic-reperfused rabbit heart. Can J Cardiol. 2003;19:267-274
35. Kamada S, Kikkawa U, Tsujimoto Y, Hunter T. Nuclear translocation of caspase-3 is dependent on its proteolytic activation and recognition of a substrate-like protein(s). J Biol Chem. 2005;280:857-860
36. Zheng TS, Schlosser SF, Dao T, Hingorani R, Crispe IN, Boyer JL, Flavell RA. Caspase-3 controls both cytoplasmic and nuclear events associated with Fas-mediated apoptosis in vivo. Proc Natl Acad Sci USA. 1998;95:13618-13623
37. Thornberry NA, Lazebnik Y. Caspases: enemies within. Science. 1998;281:1312-1316
38. Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y, Greenberg ME. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell. 1997;91:231-241
39. Scarabelli TM, Stephanou A, Pasini E, Comini L, Raddino R, Knight RA, Latchman DS. Different signaling pathways induce apoptosis in endothelial cells and cardiac myocytes during ischemia/reperfusion injury. Circ Res. 2002;90:745-748
40. Suhara T, Mano T, Oliveira BE, Walsh K. Phosphatidylinositol 3-kinase/Akt signaling controls endothelial cell sensitivity to Fasmediated apoptosis via regulation of FLICE-inhibitory protein (FLIP). Circ Res. 2001;89:13-19