Synthesis and antimicrobial and nitric oxide synthase inhibitory activities of novel isothiourea derivatives

Archives of Pharmacal Research

Volumn 33, Issue 6, 2010, Pages 821-830

  Kazimierczuk, Zygmunt ^a   Chalimoniuk, Malgorzata ^a   Laudy, Agnieszka Ewa ^b   Moo Puc, Rosa ^c   Cedillo Rivera, Roberto ^c   Starosciak, Bohdan Jerzy ^b   Chrapusta, Stanislaw J ^a  

^a MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

^b MEDICAL UNIVERSITY OF WARSAW   (Poland)

^c INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

Author keywords

Anti protozoal activity; Antibacterial activity; Antifungal activity; Isothiourea derivative; Nitric oxide synthase; Synthesis

Indexed keywords

(2 NITROBENZYL)ISOTHIOUREA; (2,3,4,5,6 PENTABROMOBENZYL)ISOTHIOUREA HYDROBROMIDE; (2,4 DINITROBENZYL)ISOTHIOUREA HYDROCHLORIDE; (3,4 DICHLOROBENZYL)ISOTHIOUREA HYDROCHLORIDE; 2 (5 NITROFURAN 2 YLMETHYL)ISOTHIOUREA; 4 NITROQUINOLINE 1 OXIDE; 7 NITROINDAZOLE; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ANTIPROTOZOAL AGENT; FLUCONAZOLE; METRONIDAZOLE; NITRIC OXIDE SYNTHASE; NITROFURANTOIN; THIOUREA DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTIPROTOZOAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BACTERIAL STRAIN; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; GENOTOXICITY; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; MALE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROTOZOON; RAT; YEAST;

ANIMALS; ANTI-INFECTIVE AGENTS; ANTIPROTOZOAL AGENTS; BRAIN; DRUG DESIGN; ENTAMOEBA HISTOLYTICA; ENZYME INHIBITORS; GIARDIA LAMBLIA; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; INHIBITORY CONCENTRATION 50; MALE; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; MUTAGENICITY TESTS; NITRIC OXIDE SYNTHASE; PARASITIC SENSITIVITY TESTS; RATS; RATS, WISTAR; THIOUREA; TRANSITION TEMPERATURE; YEASTS;

EID: 77954526783     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-010-0604-8     Document Type: Article

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