Novel prodrugs of cyanamide that inhibit aldehyde dehydrogenase in vivo

Journal of Medicinal Chemistry

Volumn 40, Issue 12, 1997, Pages 1870-1875

  Shirota, Frances N ^a   Stevens Johnk, Janell M ^b   DeMaster, Eugene G ^a   Nagasawa, Herbert T ^a,b  

^a VA MEDICAL CENTER   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 BENZYLIMIDAZOLE; ALCOHOL; ALDEHYDE DEHYDROGENASE; CYANAMIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; S BENZYLISOTHIOUREA; S BUTYLISOTHIOUREA HYDROBROMIDE; S HEXADECYLISOTHIOUREA; S ISOBUTYLISOTHIOUREA HYDROCHLORIDE; S METHYLPSEUDOTHIOUREA; UNCLASSIFIED DRUG;

ALCOHOL BLOOD LEVEL; ALCOHOL METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRADYCARDIA; ENZYME INHIBITION; LIVER MICROSOME; LIVER TOXICITY; MALE; NEPHROTOXICITY; NONHUMAN; RAT; SEPTIC SHOCK;

ACETALDEHYDE; ALDEHYDE DEHYDROGENASE; ANIMALS; CATALASE; CYANAMIDE; ENZYME INHIBITORS; ETHANOL; MALE; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; NADP; PRODRUGS; RATS; RATS, SPRAGUE-DAWLEY; THIOUREA;

EID: 0030951938     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9606296     Document Type: Article

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