Synthesis and preliminary antibacterial evaluation of 2-butyl succinate-based hydroxamate derivatives containing isoxazole rings

Archives of Pharmacal Research

Volumn 33, Issue 6, 2010, Pages 831-842

  Zhang, Datong ^a,b   Jia, Jiong ^a   Meng, Lijuan ^a   Xu, Weiren ^c   Tang, Lida ^c   Wang, Jianwu ^a  

^a SHANDONG UNIVERSITY   (China)

^b QILU UNIVERSITY OF TECHNOLOGY   (China)

^c TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH   (China)

Author keywords

2 Butyl succinate based hydroxamate derivatives; Antibacterial activity; Isoxazole; Synthesis

Indexed keywords

2 BUTYL N 4 HYDROXY N 1 [(3 2 CHLOROPHENYISOXAZOL 5 YL)METHYL]SUCCINAMIDE; 2 BUTYL N 4 HYDROXY N 1 [(3 3 TRIFLUOROMETHYLPHENYISOXAZOL 5 YL)METHYL]SUCCINAMIDE; 2 BUTYL N 4 HYDROXY N 1 [(3 4 CHLOROPHENYISOXAZOL 5 YL)METHYL]SUCCINAMIDE; 2 BUTYL N 4 HYDROXY N 1 [(3 4 METHYLPHENYISOXAZOL 5 YL)METHYL]SUCCINAMIDE; 2 BUTYL N 4 HYDROXY N 1 [1 (3 PHENYLISOXAZOL 5 YL)]PENTYLSUCCINAMIDE; 2 BUTYL N 4 HYDROXY N 1 [1 [3 (2 CHLOROPHENYL)ISOXAZOL 5 YL] 3 METHYL]BUTYLSUCCINAMIDE; 2 BUTYL N 4 HYDROXY N 1 [1 [3 (4 METHYLPHENYL)ISOXAZOL 5 YL] 3 METHYL]BUTYLSUCCINAMIDE; 2 BUTYL N 4 HYDROXY N 1 [[[3 (3,4 DICHLOROPHENYL)ISOXAZOL] 5 YL]METHYL]SUCCINAMIDE; HYDROXAMIC ACID DERIVATIVE; ISOXAZOLE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; DRUG EFFICACY; DRUG SCREENING; DRUG SYNTHESIS; KLEBSIELLA PNEUMONIAE; NONHUMAN; STAPHYLOCOCCUS AUREUS;

AMIDOHYDROLASES; ANTI-BACTERIAL AGENTS; DRUG DESIGN; ENZYME INHIBITORS; HYDROXAMIC ACIDS; KLEBSIELLA PNEUMONIAE; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; OPTICAL ROTATION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP; SUCCINATES; TRANSITION TEMPERATURE;

EID: 77954490085     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-010-0605-7     Document Type: Article

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