Fermented milks from Enterococcus faecalis TH563 and Lactobacillus delbrueckii subsp. bulgaricus LA2 manifest different degrees of ACE-inhibitory and immunomodulatory activities

Dairy Science and Technology

Volumn 90, Issue 4, 2010, Pages 469-476

  Regazzo, Daniela ^a   Da Dalt, Laura ^a   Lombardi, Angiolella ^b   Andrighetto, Christian ^b   Negro, Alessandro ^a   Gabai, Gianfranco ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b Istituto per la Qualita e le Tecnologie Agroalimentari   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA (MICROORGANISMS); BOVINAE; ENTEROCOCCUS FAECALIS; LACTOBACILLUS DELBRUECKII; LACTOBACILLUS DELBRUECKII SUBSP. BULGARICUS;

EID: 77954372978     PISSN: 19585586     EISSN: 19585594     Source Type: Journal    
DOI: 10.1051/dst/2010009     Document Type: Conference Paper

References (29)

1. Andrighetto C., Knijff E., Lombardi A., Torriani S., Vancanneyt M., Kersters K., Swings J., Dellaglio F., Phenotypic and genetic diversity of enterococci isolated from Italian cheeses, J. Dairy Res. 68 (2001) 303-316.
2. Andrighetto C., Marcazzan G., Cariolato D., Storti A., Cattelan A., Lombardi A., Isolation and characterization of microrganisms from traditional Triveneto cheeses, Sci. Tecn. Latt-Cas. 57 (2006) 309-318.
3. Cariolato D., Andrighetto C., Lombardi A., Occurrence of virulence factors and antibiotic resistance in Enterococcus faecalis and Enterococcus faecium collected from dairy and human samples in North of Italy, Food Control 19 (2008) 886-892.
4. Cushman D.W., Cheung H.S., Spectrophotometric assay and properties of the angiotensin- converting enzyme of rabbit lung, Biochem. Pharmacol. 20 (1971) 1637-1648.
5. De Simone C., Bianchi Salvadori B., Negri R., Ferrazzi M., Baldinelli M., Vesely R., The adjuvant effect of yogurt on production of gamma-interferon by con A-stimulated human peripheral blood lymphocytes, Nutr. Rep. Int. 33 (1986) 419-433.
6. Donkor O.N., Henriksson A., Vasiljevic T., Shah N.P., Proteolytic activity of dairy lactic acid bacteria and probiotics as determinant of growth and in vitro angiotensin-converting enzyme inhibitory activity in fermented milk, Lait 87 (2007) 21-38.
7. Ewaschuk J.B., Walker J.W., Diaz H., Madsen K.L., Bioproduction of conjugated linoleic acid by probiotic bacteria occurs in vitro and in vivo in mice, J. Nutr. 136 (2006) 1483-1487.
8. Franz C.M., Holzapfel W.H., Stiles M.E., Enterococci at the crossroads of food safety?, Int. J. Food Microbiol. 47 (1999) 1-24.
9. Fujiwara S., Kadooka Y., Hirita T., Nakazato H., Screening for mitogenic activity of food microorganisms and their skim milk culture supernatants, J. Jpn. Soc. Nutr. Food Sci. 43 (1990) 203-208.
10. Gobbetti M., Ferranti P., Smacchi E., Goffredi F., Addeo F., Production of angiotensin-Iconverting- enzyme-inhibitory peptides in fermented milks started by Lactobacillus delbrueckii subsp. bulgaricus SS1 and Lactococcus lactis subsp. cremoris FT4, Appl. Environ. Microbiol. 66 (2000) 3898-3904.
11. HayesM.,RossR.P.,FitzgeraldR.J.,StantonC., Putting microbes into work: dairy fermentation, cell factories and bioactive peptides. Part I: overview, Biotechnol. J. 2 (2007) 435-439.
12. Hernandez-Ledesma B., Amigo L., Ramos M., Recio I., Angiotensin converting enzyme inhibitory activity in commercial fermented products. Formation of peptides under simulated gastrointestinal digestion, J. Agric. Food Chem. 52 (2004) 1504-1510.
13. Hull M.E., Studies on milk proteins. Colorimetric determination of the partial hydrolysis of the proteins in milk, J. Dairy Sci. 30 (1947) 881-884.
14. IDF, Dairy Starter Cultures of Lactic Acid Bacteria (LAB) - Standard of Identity, Standard 149A, International Dairy Federation, Brussels, Belgium, 1997.
15. Layne E., Spectrophotometric and turbidimetric methods for measuring proteins, in: Colowick S.P., Kaplan N.O. (Eds.), Methods in Enzymology, Academic Press Inc., New York, USA, 1957, pp. 447-455.
16. Maeno M., Yamamoto N., Takano T., Identification of an antihypertensive peptide from casein hydrolysate produced by a proteinase from Lactobacillus helveticus CP790, J. Dairy Sci. 79 (1996) 1316-1321.
17. Miguel M., Muguerza B., Sanchez E., Delgado M.A., Recio I., Ramos M., Aleixandre M.A., Changes in arterial blood pressure in hypertensive rats caused by longterm intake of milk fermented by Enterococcus faecalis CECT 5728, Br. J. Nutr. 94 (2005) 36-43.
18. Moller N.P., Scholz-Ahrens K.E., Roos N., Schrezenmeir J., Bioactive peptides and proteins from foods: indication for health effects, Eur. J. Nutr. 47 (2008) 171-182.
19. Muguerza B., Ramos M., Sanchez E., Manso M.A., Miguel M., Aleixandre A., Delgado M.A., Recio I., Antihypertensive activity of milk fermented by Enterococcus faecalis strains isolated from raw milk, Int. Dairy J. 16 (2006) 61-69.
20. NakamuraY.,Yamamoto N., Sakai K., Okubo A., Yamazaki S., Takano T., Purification and characterization of angiotensin I-converting enzyme-inhibitors from sour milk, J. Dairy Sci. 78 (1995) 777-783.
21. Nakamura Y., Yamamoto N., Sakai K., Takano T., Antihypertensive effect of sour milk and peptides isolated from it that are inhibitors to angiotensin I-converting enzyme, J. Dairy Sci. 78 (1995) 1253-1257.
22. Narva M., Halleen J., Vaananen K., Korpela R., Effects of Lactobacillus helveticus fermented milk on bone cells in vitro, Life Sci. 75 (2004) 1727-1734.
23. Nielsen M.S., Martinussen T., Flambart B., Sorensen K.I., Otte J., Peptide profiles and angiotensin-I-converting enzyme inhibitory activity of fermented milk products: effect of bacterial strain, fermentation pH, and storage time, Int. Dairy J. 19 (2009) 155-165.
24. Parra M.D., Martinez de Morentin B.E., Cobo J.M., Mateos A., Martinez J.A., Daily ingestion of fermented milk containing Lactobacillus casei DN114001 improves innatedefense capacity in healthymiddle-aged people, J. Physiol. Biochem. 60 (2004) 85-91.
25. Quiros A., Ramos M., Muguerza B., Delgado M.A., Miguel M., Aleixandre A., Recio I., Identification of novel antihypertensive peptides in milk fermented with Enterococcus faecalis, Int. Dairy J. 17 (2007) 33-41.
26. Rachid M., Matar C., Duarte J., Perdigon G., Effect of milk fermented with a Lactobacillus helveticus R389(+) proteolytic strain on the immune system and on the growth of 471 breast cancer cells in mice, FEMS Immunol. Med. Microbiol. 47 (2006) 242-253.
27. Sarantinopoulos P., Andrighetto C., Georgalaki M.D., Rea M.C., Lombardi A., Cogan T.M., Kalantzopoulos G., Tsakalidou E., Biochemical properties of enterococci relevant to their technological performance, Int. Dairy J. 11 (2001) 621-647.
28. Templer S.P., Rohner P., Baumgartner A., Relation of Enterococcus faecalis and Enterococcus faecium isolates from foods and clinical specimens, J. Food Prot. 71 (2008) 2100-2104.
29. Wu J.P., Aluko R.E., Nakai S., Structural requirements of angiotensin I-converting enzyme inhibitory peptides: quantitative structure-activity relationship study of di- and tripeptides, J. Agric. Food Chem. 54 (2006) 732-738. (Pubitemid 43274109)