Protein phosphatase 2A acts as a mitogen-activated protein kinase kinase kinase 3 (MEKK3) phosphatase to inhibit lysophosphatidic acid-induced IκB kinase β/nuclear factor-κB activation

Journal of Biological Chemistry

Volumn 285, Issue 28, 2010, Pages 21341-21348

  Sun, Wenjing ^a,b   Wang, Hao ^a,b   Zhao, Xiumei ^a,b   Yu, Yang ^a   Fan, Yihui ^a   Wang, Xishan ^b   Lu, Xiongbin ^c   Zhang, Guiyin ^b   Fu, Songbin ^b   Yang, Jianhua ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b HARBIN MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC SUBUNITS; DEPHOSPHORYLATIONS; FUNCTIONAL GENOMICS; ISOFORMS; KINASE ACTIVITY; LYSOPHOSPHATIDIC ACID; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE; NUCLEAR FACTORS; OVER-EXPRESSION; PROTEIN PHOSPHATASE 2A; SIGNALING COMPONENTS;

ACIDS; PHOSPHOLIPIDS; PHOSPHORYLATION; PROTEINS;

PHOSPHATASES;

I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LYSOPHOSPHATIDIC ACID; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 3 PHOSPHATASE; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN SERINE THREONINE KINASE; SERINE; THREONINE; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; DEPHOSPHORYLATION; EMBRYO; ENZYME ACTIVE SITE; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FUNCTIONAL GENOMICS; GENE ACTIVATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

CELL LINE; HELA CELLS; HUMANS; I-KAPPA B KINASE; LYSOPHOSPHOLIPIDS; MAP KINASE KINASE KINASE 3; NF-KAPPA B; PHOSPHORYLATION; PROTEIN ISOFORMS; PROTEIN PHOSPHATASE 2; RETROVIRIDAE; RNA, SMALL INTERFERING; SERINE; SIGNAL TRANSDUCTION; THREONINE;

EID: 77954363053     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.104224     Document Type: Article

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