-
1
-
-
34250020201
-
Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis
-
El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 2007; 132: 2557-2576
-
(2007)
Gastroenterology
, vol.132
, pp. 2557-2576
-
-
El-Serag, H.B.1
Rudolph, K.L.2
-
2
-
-
33747830764
-
Hepatocellular carcinoma pathogenesis: From genes to environment
-
Farazi PA, DePinho RA. Hepatocellular carcinoma pathogenesis: from genes to environment. Nat Rev Cancer 2006; 6: 674-687
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 674-687
-
-
Farazi, P.A.1
Depinho, R.A.2
-
3
-
-
0141828970
-
Mechanisms of human hepatocarcinogenesis
-
Coleman WB. Mechanisms of human hepatocarcinogenesis. Curr Mol Med 2003; 3: 573-588
-
(2003)
Curr Mol Med
, vol.3
, pp. 573-588
-
-
Coleman, W.B.1
-
4
-
-
20344399151
-
Early hepatocellular carcinoma and dysplastic nodules
-
Kojiro M, Roskams T. Early hepatocellular carcinoma and dysplastic nodules. Semin Liver Dis 2005; 25: 133-142
-
(2005)
Semin Liver Dis
, vol.25
, pp. 133-142
-
-
Kojiro, M.1
Roskams, T.2
-
5
-
-
58149376548
-
Molecular mechanisms of hepatocellular carcinoma
-
Aravalli RN, Steer CJ, Cressman EN. Molecular mechanisms of hepatocellular carcinoma. Hepatology 2008; 48: 2047-2063
-
(2008)
Hepatology
, vol.48
, pp. 2047-2063
-
-
Aravalli, R.N.1
Steer, C.J.2
Cressman, E.N.3
-
6
-
-
67650227488
-
Avila MA. The epidermal growth factor receptor: A link between inflammation and liver cancer
-
Berasain C, Perugorria MJ, Latasa MU, Castillo J, Goñi S, Santamaría M, Prieto J, Avila MA. The epidermal growth factor receptor: a link between inflammation and liver cancer. Exp Biol Med (Maywood) 2009; 234: 713-725
-
(2009)
Exp Biol Med (Maywood)
, vol.234
, pp. 713-725
-
-
Berasain, C.1
Perugorria, M.J.2
Latasa, M.U.3
Castillo, J.4
Goñi, S.5
Santamaría, M.6
Prieto, J.7
-
7
-
-
74049140048
-
Inflammation and cancer: Interweaving microRNA, free radical, cytokine and p53 pathways
-
Schetter AJ, Heegaard NH, Harris CC. Inflammation and cancer: interweaving microRNA, free radical, cytokine and p53 pathways. Carcinogenesis 2010; 31: 37-49
-
(2010)
Carcinogenesis
, vol.31
, pp. 37-49
-
-
Schetter, A.J.1
Heegaard, N.H.2
Harris, C.C.3
-
8
-
-
34548781396
-
Genetic diversity of hepatocellular carcinomas and its potential impact on targeted therapies
-
Zucman-Rossi J, Laurent-Puig P. Genetic diversity of hepatocellular carcinomas and its potential impact on targeted therapies. Pharmacogenomics 2007; 8: 997-1003
-
(2007)
Pharmacogenomics
, vol.8
, pp. 997-1003
-
-
Zucman-Rossi, J.1
Laurent-Puig, P.2
-
9
-
-
67650224486
-
Pascale RM. Genetic and epigenetic control of molecular alterations in hepatocellular carcinoma
-
Feo F, Frau M, Tomasi ML, Brozzetti S, Pascale RM. Genetic and epigenetic control of molecular alterations in hepatocellular carcinoma. Exp Biol Med (Maywood) 2009; 234: 726-736
-
(2009)
Exp Biol Med (Maywood)
, vol.234
, pp. 726-736
-
-
Feo, F.1
Frau, M.2
Tomasi, M.L.3
Brozzetti, S.4
-
10
-
-
41649107645
-
Analysis of the mechanisms mediating tumor-specific changes in gene expression in human liver tumors
-
Acevedo LG, Bieda M, Green R, Farnham PJ. Analysis of the mechanisms mediating tumor-specific changes in gene expression in human liver tumors. Cancer Res 2008; 68: 2641-2651
-
(2008)
Cancer Res
, vol.68
, pp. 2641-2651
-
-
Acevedo, L.G.1
Bieda, M.2
Green, R.3
Farnham, P.J.4
-
11
-
-
65949098918
-
Identification of potential driver genes in human liver carcinoma by genomewide screening
-
Woo HG, Park ES, Lee JS, Lee YH, Ishikawa T, Kim YJ, Thorgeirsson SS. Identification of potential driver genes in human liver carcinoma by genomewide screening. Cancer Res 2009; 69: 4059-4066
-
(2009)
Cancer Res
, vol.69
, pp. 4059-4066
-
-
Woo, H.G.1
Park, E.S.2
Lee, J.S.3
Lee, Y.H.4
Ishikawa, T.5
Kim, Y.J.6
Thorgeirsson, S.S.7
-
12
-
-
70349739285
-
Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma
-
Hoshida Y, Nijman SM, Kobayashi M, Chan JA, Brunet JP, Chiang DY, Villanueva A, Newell P, Ikeda K, Hashimoto M, Watanabe G, Gabriel S, Friedman SL, Kumada H, Llovet JM, Golub TR. Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma. Cancer Res 2009; 69: 7385-7392
-
(2009)
Cancer Res
, vol.69
, pp. 7385-7392
-
-
Hoshida, Y.1
Nijman, S.M.2
Kobayashi, M.3
Chan, J.A.4
Brunet, J.P.5
Chiang, D.Y.6
Villanueva, A.7
Newell, P.8
Ikeda, K.9
Hashimoto, M.10
Watanabe, G.11
Gabriel, S.12
Friedman, S.L.13
Kumada, H.14
Llovet, J.M.15
Golub, T.R.16
-
15
-
-
77951915307
-
Hepatocellular carcinoma: Novel molecular approaches for diagnosis, prognosis, and therapy
-
Villanueva A, Minguez B, Forner A, Reig M, Llovet JM. Hepatocellular carcinoma: novel molecular approaches for diagnosis, prognosis, and therapy. Annu Rev Med 2010; 61: 317-328
-
(2010)
Annu Rev Med
, vol.61
, pp. 317-328
-
-
Villanueva, A.1
Minguez, B.2
Forner, A.3
Reig, M.4
Llovet, J.M.5
-
16
-
-
70449723255
-
High resolution analysis of the human transcriptome: Detection of extensive alternative splicing independent of transcriptional activity
-
Zhou W, Calciano MA, Jordan H, Brenner M, Johnson S, Wu D, Lei L, Pallares D, Beurdeley P, Rouet F, Gill PS, Bracco L, Soucaille C, Einstein R. High resolution analysis of the human transcriptome: detection of extensive alternative splicing independent of transcriptional activity. BMC Genet 2009; 10: 63
-
(2009)
BMC Genet
, vol.10
, pp. 63
-
-
Zhou, W.1
Calciano, M.A.2
Jordan, H.3
Brenner, M.4
Johnson, S.5
Wu, D.6
Lei, L.7
Pallares, D.8
Beurdeley, P.9
Rouet, F.10
Gill, P.S.11
Bracco, L.12
Soucaille, C.13
Einstein, R.14
-
17
-
-
56549101959
-
Alternative isoform regulation in human tissue transcriptomes
-
Wang ET, Sandberg R, Luo S, Khrebtukova I, Zhang L, Mayr C, Kingsmore SF, Schroth GP, Burge CB. Alternative isoform regulation in human tissue transcriptomes. Nature 2008; 456: 470-476
-
(2008)
Nature
, vol.456
, pp. 470-476
-
-
Wang, E.T.1
Sandberg, R.2
Luo, S.3
Khrebtukova, I.4
Zhang, L.5
Mayr, C.6
Kingsmore, S.F.7
Schroth, G.P.8
Burge, C.B.9
-
18
-
-
38049061206
-
Alternative splicing: Current perspectives
-
Kim E, Goren A, Ast G. Alternative splicing: current perspectives. Bioessays 2008; 30: 38-47
-
(2008)
Bioessays
, vol.30
, pp. 38-47
-
-
Kim, E.1
Goren, A.2
Ast, G.3
-
19
-
-
72849106592
-
RNA processing and its regulation: Global insights into biological networks
-
Licatalosi DD, Darnell RB. RNA processing and its regulation: global insights into biological networks. Nat Rev Genet 2010; 11: 75-87
-
(2010)
Nat Rev Genet
, vol.11
, pp. 75-87
-
-
Licatalosi, D.D.1
Darnell, R.B.2
-
20
-
-
34548758543
-
Splicing in disease: Disruption of the splicing code and the decoding machinery
-
Wang GS, Cooper TA. Splicing in disease: disruption of the splicing code and the decoding machinery. Nat Rev Genet 2007; 8: 749-761
-
(2007)
Nat Rev Genet
, vol.8
, pp. 749-761
-
-
Wang, G.S.1
Cooper, T.A.2
-
21
-
-
33746927884
-
The connection between splicing and cancer
-
Srebrow A, Kornblihtt AR. The connection between splicing and cancer. J Cell Sci 2006; 119: 2635-2641
-
(2006)
J Cell Sci
, vol.119
, pp. 2635-2641
-
-
Srebrow, A.1
Kornblihtt, A.R.2
-
22
-
-
37349089805
-
Insights into the connection between cancer and alternative splicing
-
Kim E, Goren A, Ast G. Insights into the connection between cancer and alternative splicing. Trends Genet 2008; 24: 7-10
-
(2008)
Trends Genet
, vol.24
, pp. 7-10
-
-
Kim, E.1
Goren, A.2
Ast, G.3
-
23
-
-
55549143293
-
The emerging role of splicing factors in cancer
-
Grosso AR, Martins S, Carmo-Fonseca M. The emerging role of splicing factors in cancer. EMBO Rep 2008; 9: 1087-1093
-
(2008)
EMBO Rep
, vol.9
, pp. 1087-1093
-
-
Grosso, A.R.1
Martins, S.2
Carmo-Fonseca, M.3
-
24
-
-
38449111154
-
Pre-mRNA splicing aberrations and cancer
-
Pettigrew CA, Brown MA. Pre-mRNA splicing aberrations and cancer. Front Biosci 2008; 13: 1090-1105
-
(2008)
Front Biosci
, vol.13
, pp. 1090-1105
-
-
Pettigrew, C.A.1
Brown, M.A.2
-
25
-
-
68449085340
-
Alternative splicing of pre-mRNA in cancer: Focus on G protein-coupled peptide hormone receptors
-
Körner M, Miller LJ. Alternative splicing of pre-mRNA in cancer: focus on G protein-coupled peptide hormone receptors. Am J Pathol 2009; 175: 461-472
-
(2009)
Am J Pathol
, vol.175
, pp. 461-472
-
-
Körner, M.1
Miller, L.J.2
-
27
-
-
0033835333
-
Sorting out the complexity of SR protein functions
-
Graveley BR. Sorting out the complexity of SR protein functions. RNA 2000; 6: 1197-1211
-
(2000)
RNA
, vol.6
, pp. 1197-1211
-
-
Graveley, B.R.1
-
28
-
-
4444272979
-
Cell signalling and the control of premRNA splicing
-
Shin C, Manley JL. Cell signalling and the control of premRNA splicing. Nat Rev Mol Cell Biol 2004; 5: 727-738
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 727-738
-
-
Shin, C.1
Manley, J.L.2
-
30
-
-
38349085591
-
Regulation of alternative splicing by reversible protein phosphorylation
-
Stamm S. Regulation of alternative splicing by reversible protein phosphorylation. J Biol Chem 2008; 283: 1223-1227
-
(2008)
J Biol Chem
, vol.283
, pp. 1223-1227
-
-
Stamm, S.1
-
31
-
-
17244383094
-
Stress alters the subcellular distribution of hSlu7 and thus modulates alternative splicing
-
Shomron N, Alberstein M, Reznik M, Ast G. Stress alters the subcellular distribution of hSlu7 and thus modulates alternative splicing. J Cell Sci 2005; 118: 1151-1159
-
(2005)
J Cell Sci
, vol.118
, pp. 1151-1159
-
-
Shomron, N.1
Alberstein, M.2
Reznik, M.3
Ast, G.4
-
32
-
-
28544450763
-
Concerted regulation of nuclear and cytoplasmic activities of SR proteins by AKT
-
Blaustein M, Pelisch F, Tanos T, Muñoz MJ, Wengier D, Quadrana L, Sanford JR, Muschietti JP, Kornblihtt AR, Cáceres JF, Coso OA, Srebrow A. Concerted regulation of nuclear and cytoplasmic activities of SR proteins by AKT. Nat Struct Mol Biol 2005; 12: 1037-1044
-
(2005)
Nat Struct Mol Biol
, vol.12
, pp. 1037-1044
-
-
Blaustein, M.1
Pelisch, F.2
Tanos, T.3
Muñoz, M.J.4
Wengier, D.5
Quadrana, L.6
Sanford, J.R.7
Muschietti, J.P.8
Kornblihtt, A.R.9
Cáceres, J.F.10
Coso, O.A.11
Srebrow, A.12
-
33
-
-
33847308702
-
Fas-activated serine/threonine kinase (FAST K) synergizes with TIA-1/TIAR proteins to regulate Fas alternative splicing
-
Izquierdo JM, Valcárcel J. Fas-activated serine/threonine kinase (FAST K) synergizes with TIA-1/TIAR proteins to regulate Fas alternative splicing. J Biol Chem 2007; 282: 1539-1543
-
(2007)
J Biol Chem
, vol.282
, pp. 1539-1543
-
-
Izquierdo, J.M.1
Valcárcel, J.2
-
34
-
-
20244372405
-
Molecular and genetic studies imply Akt-mediated signaling promotes protein kinase CbetaII alternative splicing via phosphorylation of serine/arginine-rich splicing factor SRp40
-
Patel NA, Kaneko S, Apostolatos HS, Bae SS, Watson JE, Davidowitz K, Chappell DS, Birnbaum MJ, Cheng JQ, Cooper DR. Molecular and genetic studies imply Akt-mediated signaling promotes protein kinase CbetaII alternative splicing via phosphorylation of serine/arginine-rich splicing factor SRp40. J Biol Chem 2005; 280: 14302-14309
-
(2005)
J Biol Chem
, vol.280
, pp. 14302-14309
-
-
Patel, N.A.1
Kaneko, S.2
Apostolatos, H.S.3
Bae, S.S.4
Watson, J.E.5
Davidowitz, K.6
Chappell, D.S.7
Birnbaum, M.J.8
Cheng, J.Q.9
Cooper, D.R.10
-
35
-
-
33745606029
-
A positive feedback loop couples Ras activation and CD44 alternative splicing
-
Cheng C, Yaffe MB, Sharp PA. A positive feedback loop couples Ras activation and CD44 alternative splicing. Genes Dev 2006; 20: 1715-1720
-
(2006)
Genes Dev
, vol.20
, pp. 1715-1720
-
-
Cheng, C.1
Yaffe, M.B.2
Sharp, P.A.3
-
36
-
-
42949176197
-
Ras promotes growth by alternative splicing-mediated inactivation of the KLF6 tumor suppressor in hepatocellular carcinoma
-
Yea S, Narla G, Zhao X, Garg R, Tal-Kremer S, Hod E, Villanueva A, Loke J, Tarocchi M, Akita K, Shirasawa S, Sasazuki T, Martignetti JA, Llovet JM, Friedman SL. Ras promotes growth by alternative splicing-mediated inactivation of the KLF6 tumor suppressor in hepatocellular carcinoma. Gastroenterology 2008; 134: 1521-1531
-
(2008)
Gastroenterology
, vol.134
, pp. 1521-1531
-
-
Yea, S.1
Narla, G.2
Zhao, X.3
Garg, R.4
Tal-Kremer, S.5
Hod, E.6
Villanueva, A.7
Loke, J.8
Tarocchi, M.9
Akita, K.10
Shirasawa, S.11
Sasazuki, T.12
Martignetti, J.A.13
Llovet, J.M.14
Friedman, S.L.15
-
37
-
-
70350122931
-
Amphiregulin induces the alternative splicing of p73 into its oncogenic isoform DeltaEx2p73 in human hepatocellular tumors
-
Castillo J, Goñi S, Latasa MU, Perugorría MJ, Calvo A, Muntané J, Bioulac-Sage P, Balabaud C, Prieto J, Avila MA, Berasain C. Amphiregulin induces the alternative splicing of p73 into its oncogenic isoform DeltaEx2p73 in human hepatocellular tumors. Gastroenterology 2009; 137: 1805-1815.e1-4
-
(2009)
Gastroenterology
, vol.137
-
-
Castillo, J.1
Goñi, S.2
Latasa, M.U.3
Perugorría, M.J.4
Calvo, A.5
Muntané, J.6
Bioulac-Sage, P.7
Balabaud, C.8
Prieto, J.9
Avila, M.A.10
Berasain, C.11
-
38
-
-
21844480906
-
Crosstalk between signaling pathways regulates alternative splicing: A novel role for JNK
-
Pelisch F, Blaustein M, Kornblihtt AR, Srebrow A. Crosstalk between signaling pathways regulates alternative splicing: a novel role for JNK. J Biol Chem 2005; 280: 25461-25469
-
(2005)
J Biol Chem
, vol.280
, pp. 25461-25469
-
-
Pelisch, F.1
Blaustein, M.2
Kornblihtt, A.R.3
Srebrow, A.4
-
40
-
-
33646240135
-
Two-dimensional transcriptome profiling: Identification of messenger RNA isoform signatures in prostate cancer from archived paraffin-embedded cancer specimens
-
Li HR, Wang-Rodriguez J, Nair TM, Yeakley JM, Kwon YS, Bibikova M, Zheng C, Zhou L, Zhang K, Downs T, Fu XD, Fan JB. Two-dimensional transcriptome profiling: identification of messenger RNA isoform signatures in prostate cancer from archived paraffin-embedded cancer specimens. Cancer Res 2006; 66: 4079-4088
-
(2006)
Cancer Res
, vol.66
, pp. 4079-4088
-
-
Li, H.R.1
Wang-Rodriguez, J.2
Nair, T.M.3
Yeakley, J.M.4
Kwon, Y.S.5
Bibikova, M.6
Zheng, C.7
Zhou, L.8
Zhang, K.9
Downs, T.10
Fu, X.D.11
Fan, J.B.12
-
41
-
-
33847630730
-
The gene encoding the splicing factor SF2/ASF is a proto-oncogene
-
Karni R, de Stanchina E, Lowe SW, Sinha R, Mu D, Krainer AR. The gene encoding the splicing factor SF2/ASF is a proto-oncogene. Nat Struct Mol Biol 2007; 14: 185-193
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 185-193
-
-
Karni, R.1
de Stanchina, E.2
Lowe, S.W.3
Sinha, R.4
Mu, D.5
Krainer, A.R.6
-
42
-
-
75149150660
-
HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer
-
David CJ, Chen M, Assanah M, Canoll P, Manley JL. HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer. Nature 2010; 463: 364-368
-
(2010)
Nature
, vol.463
, pp. 364-368
-
-
David, C.J.1
Chen, M.2
Assanah, M.3
Canoll, P.4
Manley, J.L.5
-
43
-
-
0037162542
-
Overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis
-
Saito Y, Kanai Y, Sakamoto M, Saito H, Ishii H, Hirohashi S. Overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis. Proc Natl Acad Sci USA 2002; 99: 10060-10065
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 10060-10065
-
-
Saito, Y.1
Kanai, Y.2
Sakamoto, M.3
Saito, H.4
Ishii, H.5
Hirohashi, S.6
-
44
-
-
8644236540
-
Alterations in gene expression associated with the overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, during human hepatocarcinogenesis
-
Kanai Y, Saito Y, Ushijima S, Hirohashi S. Alterations in gene expression associated with the overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, during human hepatocarcinogenesis. J Cancer Res Clin Oncol 2004; 130: 636-644
-
(2004)
J Cancer Res Clin Oncol
, vol.130
, pp. 636-644
-
-
Kanai, Y.1
Saito, Y.2
Ushijima, S.3
Hirohashi, S.4
-
45
-
-
43549115722
-
Aurora kinase B is a predictive factor for the aggressive recurrence of hepatocellular carcinoma after curative hepatectomy
-
Tanaka S, Arii S, Yasen M, Mogushi K, Su NT, Zhao C, Imoto I, Eishi Y, Inazawa J, Miki Y, Tanaka H. Aurora kinase B is a predictive factor for the aggressive recurrence of hepatocellular carcinoma after curative hepatectomy. Br J Surg 2008; 95: 611-619
-
(2008)
Br J Surg
, vol.95
, pp. 611-619
-
-
Tanaka, S.1
Arii, S.2
Yasen, M.3
Mogushi, K.4
Su, N.T.5
Zhao, C.6
Imoto, I.7
Eishi, Y.8
Inazawa, J.9
Miki, Y.10
Tanaka, H.11
-
46
-
-
62849112156
-
Expression of Aurora B and alternative variant forms in hepatocellular carcinoma and adjacent tissue
-
Yasen M, Mizushima H, Mogushi K, Obulhasim G, Miyaguchi K, Inoue K, Nakahara I, Ohta T, Aihara A, Tanaka S, Arii S, Tanaka H. Expression of Aurora B and alternative variant forms in hepatocellular carcinoma and adjacent tissue. Cancer Sci 2009; 100: 472-480
-
(2009)
Cancer Sci
, vol.100
, pp. 472-480
-
-
Yasen, M.1
Mizushima, H.2
Mogushi, K.3
Obulhasim, G.4
Miyaguchi, K.5
Inoue, K.6
Nakahara, I.7
Ohta, T.8
Aihara, A.9
Tanaka, S.10
Arii, S.11
Tanaka, H.12
-
47
-
-
0037156944
-
Cirrhotic livers reveal genetic changes in the MDM2-P14ARF system of cell cycle regulators
-
Schlott T, Scharf JG, Gorzel C, Middel P, Spring H. Cirrhotic livers reveal genetic changes in the MDM2-P14ARF system of cell cycle regulators. Br J Cancer 2002; 86: 1290-1296
-
(2002)
Br J Cancer
, vol.86
, pp. 1290-1296
-
-
Schlott, T.1
Scharf, J.G.2
Gorzel, C.3
Middel, P.4
Spring, H.5
-
48
-
-
33750631858
-
Tensin2 variant 3 is associated with aggressive tumor behavior in human hepatocellular carcinoma
-
Yam JW, Ko FC, Chan CY, Yau TO, Tung EK, Leung TH, Jin DY, Ng IO. Tensin2 variant 3 is associated with aggressive tumor behavior in human hepatocellular carcinoma. Hepatology 2006; 44: 881-890
-
(2006)
Hepatology
, vol.44
, pp. 881-890
-
-
Yam, J.W.1
Ko, F.C.2
Chan, C.Y.3
Yau, T.O.4
Tung, E.K.5
Leung, T.H.6
Jin, D.Y.7
Ng, I.O.8
-
49
-
-
66149186859
-
Aberrant splicing of Hugl-1 is associated with hepatocellular carcinoma progression
-
Lu X, Feng X, Man X, Yang G, Tang L, Du D, Zhang F, Yuan H, Huang Q, Zhang Z, Liu Y, Strand D, Chen Z. Aberrant splicing of Hugl-1 is associated with hepatocellular carcinoma progression. Clin Cancer Res 2009; 15: 3287-3296
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3287-3296
-
-
Lu, X.1
Feng, X.2
Man, X.3
Yang, G.4
Tang, L.5
Du, D.6
Zhang, F.7
Yuan, H.8
Huang, Q.9
Zhang, Z.10
Liu, Y.11
Strand, D.12
Chen, Z.13
-
50
-
-
56449096184
-
Role of a novel splice variant of mitotic arrest deficient 1 (MAD1), MAD1beta, in mitotic checkpoint control in liver cancer
-
Sze KM, Ching YP, Jin DY, Ng IO. Role of a novel splice variant of mitotic arrest deficient 1 (MAD1), MAD1beta, in mitotic checkpoint control in liver cancer. Cancer Res 2008; 68: 9194-9201
-
(2008)
Cancer Res
, vol.68
, pp. 9194-9201
-
-
Sze, K.M.1
Ching, Y.P.2
Jin, D.Y.3
Ng, I.O.4
-
51
-
-
0028137277
-
Flow cytometric analysis of DNA ploidy in hepatocellular carcinoma
-
Ng IO, Lai EC, Ho JC, Cheung LK, Ng MM, So MK. Flow cytometric analysis of DNA ploidy in hepatocellular carcinoma. Am J Clin Pathol 1994; 102: 80-86
-
(1994)
Am J Clin Pathol
, vol.102
, pp. 80-86
-
-
Ng, I.O.1
Lai, E.C.2
Ho, J.C.3
Cheung, L.K.4
Ng, M.M.5
So, M.K.6
-
52
-
-
0037742196
-
A specific splicing variant of SVH, a novel human armadillo repeat protein, is up-regulated in hepatocellular carcinomas
-
Huang R, Xing Z, Luan Z, Wu T, Wu X, Hu G. A specific splicing variant of SVH, a novel human armadillo repeat protein, is up-regulated in hepatocellular carcinomas. Cancer Res 2003; 63: 3775-3782
-
(2003)
Cancer Res
, vol.63
, pp. 3775-3782
-
-
Huang, R.1
Xing, Z.2
Luan, Z.3
Wu, T.4
Wu, X.5
Hu, G.6
-
53
-
-
0242577553
-
Identification of liver-intestine cadherin in hepatocellular carcinoma--a potential disease marker
-
Wong BW, Luk JM, Ng IO, Hu MY, Liu KD, Fan ST. Identification of liver-intestine cadherin in hepatocellular carcinoma--a potential disease marker. Biochem Biophys Res Commun 2003; 311: 618-624
-
(2003)
Biochem Biophys Res Commun
, vol.311
, pp. 618-624
-
-
Wong, B.W.1
Luk, J.M.2
Ng, I.O.3
Hu, M.Y.4
Liu, K.D.5
Fan, S.T.6
-
54
-
-
72949084408
-
Targeting cadherin-17 inactivates Wnt signaling and inhibits tumor growth in liver carcinoma
-
Liu LX, Lee NP, Chan VW, Xue W, Zender L, Zhang C, Mao M, Dai H, Wang XL, Xu MZ, Lee TK, Ng IO, Chen Y, Kung HF, Lowe SW, Poon RT, Wang JH, Luk JM. Targeting cadherin-17 inactivates Wnt signaling and inhibits tumor growth in liver carcinoma. Hepatology 2009; 50: 1453-1463
-
(2009)
Hepatology
, vol.50
, pp. 1453-1463
-
-
Liu, L.X.1
Lee, N.P.2
Chan, V.W.3
Xue, W.4
Zender, L.5
Zhang, C.6
Mao, M.7
Dai, H.8
Wang, X.L.9
Xu, M.Z.10
Lee, T.K.11
Ng, I.O.12
Chen, Y.13
Kung, H.F.14
Lowe, S.W.15
Poon, R.T.16
Wang, J.H.17
Luk, J.M.18
-
55
-
-
12244254020
-
Alternative mRNA splicing of liver intestine-cadherin in hepatocellular carcinoma
-
Wang XQ, Luk JM, Leung PP, Wong BW, Stanbridge EJ, Fan ST. Alternative mRNA splicing of liver intestine-cadherin in hepatocellular carcinoma. Clin Cancer Res 2005; 11: 483-489
-
(2005)
Clin Cancer Res
, vol.11
, pp. 483-489
-
-
Wang, X.Q.1
Luk, J.M.2
Leung, P.P.3
Wong, B.W.4
Stanbridge, E.J.5
Fan, S.T.6
-
56
-
-
33749040274
-
Liver intestine-cadherin (CDH17) haplotype is associated with increased risk of hepatocellular carcinoma
-
Wang XQ, Luk JM, Garcia-Barcelo M, Miao X, Leung PP, Ho DW, Cheung ST, Lam BY, Cheung CK, Wong AS, Lau SS, So MT, Yu WC, Cai Q, Liu KS, Hui CK, Lau GK, Poon RT, Wong J, Fan ST. Liver intestine-cadherin (CDH17) haplotype is associated with increased risk of hepatocellular carcinoma. Clin Cancer Res 2006; 12: 5248-5252
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5248-5252
-
-
Wang, X.Q.1
Luk, J.M.2
Garcia-Barcelo, M.3
Miao, X.4
Leung, P.P.5
Ho, D.W.6
Cheung, S.T.7
Lam, B.Y.8
Cheung, C.K.9
Wong, A.S.10
Lau, S.S.11
So, M.T.12
Yu, W.C.13
Cai, Q.14
Liu, K.S.15
Hui, C.K.16
Lau, G.K.17
Poon, R.T.18
Wong, J.19
Fan, S.T.20
more..
-
57
-
-
50249176028
-
New insights into form and function of fibronectin splice variants
-
White ES, Baralle FE, Muro AF. New insights into form and function of fibronectin splice variants. J Pathol 2008; 216: 1-14
-
(2008)
J Pathol
, vol.216
, pp. 1-14
-
-
White, E.S.1
Baralle, F.E.2
Muro, A.F.3
-
58
-
-
0037070605
-
Regulation of fibronectin alternative splicing by a basement membrane-like extracellular matrix
-
Srebrow A, Blaustein M, Kornblihtt AR. Regulation of fibronectin alternative splicing by a basement membrane-like extracellular matrix. FEBS Lett 2002; 514: 285-289
-
(2002)
FEBS Lett
, vol.514
, pp. 285-289
-
-
Srebrow, A.1
Blaustein, M.2
Kornblihtt, A.R.3
-
59
-
-
2442671442
-
Mammary epithelial-mesenchymal interaction regulates fibronectin alternative splicing via phosphatidylinositol 3-kinase
-
Blaustein M, Pelisch F, Coso OA, Bissell MJ, Kornblihtt AR, Srebrow A. Mammary epithelial-mesenchymal interaction regulates fibronectin alternative splicing via phosphatidylinositol 3-kinase. J Biol Chem 2004; 279: 21029-21037
-
(2004)
J Biol Chem
, vol.279
, pp. 21029-21037
-
-
Blaustein, M.1
Pelisch, F.2
Coso, O.A.3
Bissell, M.J.4
Kornblihtt, A.R.5
Srebrow, A.6
-
60
-
-
0028596335
-
Expression of variant fibronectins in wound healing: Cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis
-
Jarnagin WR, Rockey DC, Koteliansky VE, Wang SS, Bissell DM. Expression of variant fibronectins in wound healing: cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis. J Cell Biol 1994; 127: 2037-2048
-
(1994)
J Cell Biol
, vol.127
, pp. 2037-2048
-
-
Jarnagin, W.R.1
Rockey, D.C.2
Koteliansky, V.E.3
Wang, S.S.4
Bissell, D.M.5
-
61
-
-
0027175450
-
Localization and mRNA steady-state level of cellular fibronectin in rat liver undergoing a CCl4-induced acute damage or fibrosis
-
Odenthal M, Neubauer K, Meyer zum Büschenfelde KH, Ramadori G. Localization and mRNA steady-state level of cellular fibronectin in rat liver undergoing a CCl4-induced acute damage or fibrosis. Biochim Biophys Acta 1993; 1181: 266-272
-
(1993)
Biochim Biophys Acta
, vol.1181
, pp. 266-272
-
-
Odenthal, M.1
Neubauer, K.2
Meyer Zum Büschenfelde, K.H.3
Ramadori, G.4
-
62
-
-
11144234984
-
Regulation of fibronectin splicing in sinusoidal endothelial cells from normal or injured liver
-
Chang ML, Chen JC, Alonso CR, Kornblihtt AR, Bissell DM. Regulation of fibronectin splicing in sinusoidal endothelial cells from normal or injured liver. Proc Natl Acad Sci USA 2004; 101: 18093-18098
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 18093-18098
-
-
Chang, M.L.1
Chen, J.C.2
Alonso, C.R.3
Kornblihtt, A.R.4
Bissell, D.M.5
-
63
-
-
0031010393
-
HRS/ SRp40-mediated inclusion of the fibronectin EIIIB exon, a possible cause of increased EIIIB expression in proliferating liver
-
Du K, Peng Y, Greenbaum LE, Haber BA, Taub R. HRS/ SRp40-mediated inclusion of the fibronectin EIIIB exon, a possible cause of increased EIIIB expression in proliferating liver. Mol Cell Biol 1997; 17: 4096-4104
-
(1997)
Mol Cell Biol
, vol.17
, pp. 4096-4104
-
-
Du, K.1
Peng, Y.2
Greenbaum, L.E.3
Haber, B.A.4
Taub, R.5
-
64
-
-
0030663832
-
Expression, localization and alternative splicing pattern of fibronectin messenger RNA in fibrotic human liver and hepatocellular carcinoma
-
Matsui S, Takahashi T, Oyanagi Y, Takahashi S, Boku S, Takahashi K, Furukawa K, Arai F, Asakura H. Expression, localization and alternative splicing pattern of fibronectin messenger RNA in fibrotic human liver and hepatocellular carcinoma. J Hepatol 1997; 27: 843-853
-
(1997)
J Hepatol
, vol.27
, pp. 843-853
-
-
Matsui, S.1
Takahashi, T.2
Oyanagi, Y.3
Takahashi, S.4
Boku, S.5
Takahashi, K.6
Furukawa, K.7
Arai, F.8
Asakura, H.9
-
65
-
-
0027315769
-
Coordinate oncodevelopmental modulation of alternative splicing of fibronectin pre-messenger RNA at ED-A, ED-B, and CS1 regions in human liver tumors
-
Oyama F, Hirohashi S, Sakamoto M, Titani K, Sekiguchi K. Coordinate oncodevelopmental modulation of alternative splicing of fibronectin pre-messenger RNA at ED-A, ED-B, and CS1 regions in human liver tumors. Cancer Res 1993; 53: 2005-2011
-
(1993)
Cancer Res
, vol.53
, pp. 2005-2011
-
-
Oyama, F.1
Hirohashi, S.2
Sakamoto, M.3
Titani, K.4
Sekiguchi, K.5
-
66
-
-
62949123360
-
The role of KLF6 and its splice variants in cancer therapy
-
DiFeo A, Martignetti JA, Narla G. The role of KLF6 and its splice variants in cancer therapy. Drug Resist Updat 2009; 12: 1-7
-
(2009)
Drug Resist Updat
, vol.12
, pp. 1-7
-
-
Difeo, A.1
Martignetti, J.A.2
Narla, G.3
-
67
-
-
33745725772
-
Roles of KLF6 and KLF6-SV1 in ovarian cancer progression and intraperitoneal dissemination
-
DiFeo A, Narla G, Hirshfeld J, Camacho-Vanegas O, Narla J, Rose SL, Kalir T, Yao S, Levine A, Birrer MJ, Bonome T, Friedman SL, Buller RE, Martignetti JA. Roles of KLF6 and KLF6-SV1 in ovarian cancer progression and intraperitoneal dissemination. Clin Cancer Res 2006; 12: 3730-3739
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3730-3739
-
-
Difeo, A.1
Narla, G.2
Hirshfeld, J.3
Camacho-Vanegas, O.4
Narla, J.5
Rose, S.L.6
Kalir, T.7
Yao, S.8
Levine, A.9
Birrer, M.J.10
Bonome, T.11
Friedman, S.L.12
Buller, R.E.13
Martignetti, J.A.14
-
68
-
-
33947162353
-
Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation
-
Kremer-Tal S, Narla G, Chen Y, Hod E, DiFeo A, Yea S, Lee JS, Schwartz M, Thung SN, Fiel IM, Banck M, Zimran E, Thorgeirsson SS, Mazzaferro V, Bruix J, Martignetti JA, Llovet JM, Friedman SL. Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation. J Hepatol 2007; 46: 645-654
-
(2007)
J Hepatol
, vol.46
, pp. 645-654
-
-
Kremer-Tal, S.1
Narla, G.2
Chen, Y.3
Hod, E.4
Difeo, A.5
Yea, S.6
Lee, J.S.7
Schwartz, M.8
Thung, S.N.9
Fiel, I.M.10
Banck, M.11
Zimran, E.12
Thorgeirsson, S.S.13
Mazzaferro, V.14
Bruix, J.15
Martignetti, J.A.16
Llovet, J.M.17
Friedman, S.L.18
-
69
-
-
34247598862
-
New molecular targets for hepatocellular carcinoma: The ErbB1 signaling system
-
Berasain C, Castillo J, Prieto J, Avila MA. New molecular targets for hepatocellular carcinoma: the ErbB1 signaling system. Liver Int 2007; 27: 174-185
-
(2007)
Liver Int
, vol.27
, pp. 174-185
-
-
Berasain, C.1
Castillo, J.2
Prieto, J.3
Avila, M.A.4
-
70
-
-
47249130828
-
In good times and bad: P73 in cancer
-
Oswald C, Stiewe T. In good times and bad: p73 in cancer. Cell Cycle 2008; 7: 1726-1731
-
(2008)
Cell Cycle
, vol.7
, pp. 1726-1731
-
-
Oswald, C.1
Stiewe, T.2
-
71
-
-
27944476397
-
TAp73/Delta Np73 influences apoptotic response, chemosensitivity and prognosis in hepatocellular carcinoma
-
Müller M, Schilling T, Sayan AE, Kairat A, Lorenz K, Schulze-Bergkamen H, Oren M, Koch A, Tannapfel A, Stremmel W, Melino G, Krammer PH. TAp73/Delta Np73 influences apoptotic response, chemosensitivity and prognosis in hepatocellular carcinoma. Cell Death Differ 2005; 12: 1564-1577
-
(2005)
Cell Death Differ
, vol.12
, pp. 1564-1577
-
-
Müller, M.1
Schilling, T.2
Sayan, A.E.3
Kairat, A.4
Lorenz, K.5
Schulze-Bergkamen, H.6
Oren, M.7
Koch, A.8
Tannapfel, A.9
Stremmel, W.10
Melino, G.11
Krammer, P.H.12
-
72
-
-
0036628511
-
Transactivation-deficient DeltaTA-p73 acts as an oncogene
-
Stiewe T, Zimmermann S, Frilling A, Esche H, Pützer BM. Transactivation-deficient DeltaTA-p73 acts as an oncogene. Cancer Res 2002; 62: 3598-3602
-
(2002)
Cancer Res
, vol.62
, pp. 3598-3602
-
-
Stiewe, T.1
Zimmermann, S.2
Frilling, A.3
Esche, H.4
Pützer, B.M.5
-
73
-
-
0842311606
-
Quantitative TP73 transcript analysis in hepatocellular carcinomas
-
Stiewe T, Tuve S, Peter M, Tannapfel A, Elmaagacli AH, Pützer BM. Quantitative TP73 transcript analysis in hepatocellular carcinomas. Clin Cancer Res 2004; 10: 626-633
-
(2004)
Clin Cancer Res
, vol.10
, pp. 626-633
-
-
Stiewe, T.1
Tuve, S.2
Peter, M.3
Tannapfel, A.4
Elmaagacli, A.H.5
Pützer, B.M.6
-
74
-
-
17744386129
-
Transactivation-deficient p73alpha (p73Deltaexon2) inhibits apoptosis and competes with p53
-
Fillippovich I, Sorokina N, Gatei M, Haupt Y, Hobson K, Moallem E, Spring K, Mould M, McGuckin MA, Lavin MF, Khanna KK. Transactivation-deficient p73alpha (p73Deltaexon2) inhibits apoptosis and competes with p53. Oncogene 2001; 20: 514-522
-
(2001)
Oncogene
, vol.20
, pp. 514-522
-
-
Fillippovich, I.1
Sorokina, N.2
Gatei, M.3
Haupt, Y.4
Hobson, K.5
Moallem, E.6
Spring, K.7
Mould, M.8
McGuckin, M.A.9
Lavin, M.F.10
Khanna, K.K.11
-
75
-
-
0042977668
-
DeltaNp73 facilitates cell immortalization and cooperates with oncogenic Ras in cellular transformation in vivo
-
Petrenko O, Zaika A, Moll UM. deltaNp73 facilitates cell immortalization and cooperates with oncogenic Ras in cellular transformation in vivo. Mol Cell Biol 2003; 23: 5540-5555
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5540-5555
-
-
Petrenko, O.1
Zaika, A.2
Moll, U.M.3
-
76
-
-
38849116924
-
Autonomous growth and hepatocarcinogenesis in transgenic mice expressing the p53 family inhibitor DNp73
-
Tannapfel A, John K, Mise N, Schmidt A, Buhlmann S, Ibrahim SM, Pützer BM. Autonomous growth and hepatocarcinogenesis in transgenic mice expressing the p53 family inhibitor DNp73. Carcinogenesis 2008; 29: 211-218
-
(2008)
Carcinogenesis
, vol.29
, pp. 211-218
-
-
Tannapfel, A.1
John, K.2
Mise, N.3
Schmidt, A.4
Buhlmann, S.5
Ibrahim, S.M.6
Pützer, B.M.7
-
77
-
-
61649106928
-
Inflammation and liver cancer: New molecular links
-
Berasain C, Castillo J, Perugorria MJ, Latasa MU, Prieto J, Avila MA. Inflammation and liver cancer: new molecular links. Ann N Y Acad Sci 2009; 1155: 206-221
-
(2009)
Ann N Y Acad Sci
, vol.1155
, pp. 206-221
-
-
Berasain, C.1
Castillo, J.2
Perugorria, M.J.3
Latasa, M.U.4
Prieto, J.5
Avila, M.A.6
-
78
-
-
54449093971
-
Latasa MU, Nicou A, Cartagena-Lirola H, Castillo J, Goñi S, Vespasiani-Gentilucci U, Zagami MG, Lotersztajn S, Prieto J, Berasain C, Avila MA. The epidermal growth factor receptor ligand amphiregulin participates in the development of mouse liver fibrosis
-
Perugorria MJ
-
Perugorria MJ, Latasa MU, Nicou A, Cartagena-Lirola H, Castillo J, Goñi S, Vespasiani-Gentilucci U, Zagami MG, Lotersztajn S, Prieto J, Berasain C, Avila MA. The epidermal growth factor receptor ligand amphiregulin participates in the development of mouse liver fibrosis. Hepatology 2008; 48: 1251-1261
-
(2008)
Hepatology
, vol.48
, pp. 1251-1261
-
-
-
79
-
-
34447330435
-
Amphiregulin: A new growth factor in hepatocarcinogenesis
-
Berasain C, Castillo J, Perugorría MJ, Prieto J, Avila MA. Amphiregulin: a new growth factor in hepatocarcinogenesis. Cancer Lett 2007; 254: 30-41
-
(2007)
Cancer Lett
, vol.254
, pp. 30-41
-
-
Berasain, C.1
Castillo, J.2
Perugorría, M.J.3
Prieto, J.4
Avila, M.A.5
-
80
-
-
35548964231
-
Regulation of transcription of the RNA splicing factor hSlu7 by Elk-1 and Sp1 affects alternative splicing
-
Alberstein M, Amit M, Vaknin K, O'Donnell A, Farhy C, Lerenthal Y, Shomron N, Shaham O, Sharrocks AD, Ashery-Padan R, Ast G. Regulation of transcription of the RNA splicing factor hSlu7 by Elk-1 and Sp1 affects alternative splicing. RNA 2007; 13: 1988-1999
-
(2007)
RNA
, vol.13
, pp. 1988-1999
-
-
Alberstein, M.1
Amit, M.2
Vaknin, K.3
O'Donnell, A.4
Farhy, C.5
Lerenthal, Y.6
Shomron, N.7
Shaham, O.8
Sharrocks, A.D.9
Ashery-Padan, R.10
Ast, G.11
-
82
-
-
0036468922
-
A misspliced form of the cholecystokinin-B/gastrin receptor in pancreatic carcinoma: Role of reduced sellular U2AF35 and a suboptimal 3'-splicing site leading to retention of the fourth intron
-
Ding WQ, Kuntz SM, Miller LJ. A misspliced form of the cholecystokinin-B/gastrin receptor in pancreatic carcinoma: role of reduced sellular U2AF35 and a suboptimal 3'-splicing site leading to retention of the fourth intron. Cancer Res 2002; 62: 947-952
-
(2002)
Cancer Res
, vol.62
, pp. 947-952
-
-
Ding, W.Q.1
Kuntz, S.M.2
Miller, L.J.3
-
83
-
-
33749471110
-
RNA interference knockdown of hU2AF35 impairs cell cycle progression and modulates alternative splicing of Cdc25 transcripts
-
Pacheco TR, Moita LF, Gomes AQ, Hacohen N, Carmo-Fonseca M. RNA interference knockdown of hU2AF35 impairs cell cycle progression and modulates alternative splicing of Cdc25 transcripts. Mol Biol Cell 2006; 17: 4187-4199
-
(2006)
Mol Biol Cell
, vol.17
, pp. 4187-4199
-
-
Pacheco, T.R.1
Moita, L.F.2
Gomes, A.Q.3
Hacohen, N.4
Carmo-Fonseca, M.5
-
84
-
-
45249091505
-
Substances that can change alternative splice-site selection
-
Sumanasekera C, Watt DS, Stamm S. Substances that can change alternative splice-site selection. Biochem Soc Trans 2008; 36: 483-490
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 483-490
-
-
Sumanasekera, C.1
Watt, D.S.2
Stamm, S.3
-
86
-
-
63849152847
-
Progress toward therapy with antisensemediated splicing modulation
-
Du L, Gatti RA. Progress toward therapy with antisensemediated splicing modulation. Curr Opin Mol Ther 2009; 11: 116-123
-
(2009)
Curr Opin Mol Ther
, vol.11
, pp. 116-123
-
-
Du, L.1
Gatti, R.A.2
-
87
-
-
34548095157
-
Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of premRNA
-
Kaida D, Motoyoshi H, Tashiro E, Nojima T, Hagiwara M, Ishigami K, Watanabe H, Kitahara T, Yoshida T, Nakajima H, Tani T, Horinouchi S, Yoshida M. Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of premRNA. Nat Chem Biol 2007; 3: 576-583
-
(2007)
Nat Chem Biol
, vol.3
, pp. 576-583
-
-
Kaida, D.1
Motoyoshi, H.2
Tashiro, E.3
Nojima, T.4
Hagiwara, M.5
Ishigami, K.6
Watanabe, H.7
Kitahara, T.8
Yoshida, T.9
Nakajima, H.10
Tani, T.11
Horinouchi, S.12
Yoshida, M.13
-
88
-
-
34548104659
-
Splicing factor SF3b as a target of the antitumor natural product pladienolide
-
Kotake Y, Sagane K, Owa T, Mimori-Kiyosue Y, Shimizu H, Uesugi M, Ishihama Y, Iwata M, Mizui Y. Splicing factor SF3b as a target of the antitumor natural product pladienolide. Nat Chem Biol 2007; 3: 570-575
-
(2007)
Nat Chem Biol
, vol.3
, pp. 570-575
-
-
Kotake, Y.1
Sagane, K.2
Owa, T.3
Mimori-Kiyosue, Y.4
Shimizu, H.5
Uesugi, M.6
Ishihama, Y.7
Iwata, M.8
Mizui, Y.9
-
89
-
-
0035884180
-
Specific inhibition of serine- and arginine-rich splicing factors phosphorylation, spliceosome assembly, and splicing by the antitumor drug NB-506
-
Pilch B, Allemand E, Facompré M, Bailly C, Riou JF, Soret J, Tazi J. Specific inhibition of serine- and arginine-rich splicing factors phosphorylation, spliceosome assembly, and splicing by the antitumor drug NB-506. Cancer Res 2001; 61: 6876-6884
-
(2001)
Cancer Res
, vol.61
, pp. 6876-6884
-
-
Pilch, B.1
Allemand, E.2
Facompré, M.3
Bailly, C.4
Riou, J.F.5
Soret, J.6
Tazi, J.7
-
90
-
-
29144463738
-
Alternative splicing: A new drug target of the post-genome era
-
Hagiwara M. Alternative splicing: a new drug target of the post-genome era. Biochim Biophys Acta 2005; 1754: 324-331
-
(2005)
Biochim Biophys Acta
, vol.1754
, pp. 324-331
-
-
Hagiwara, M.1
-
91
-
-
33947223157
-
Serine-arginine protein kinase 1 overexpression is associated with tumorigenic imbalance in mitogen-activated protein kinase pathways in breast, colonic, and pancreatic carcinomas
-
Hayes GM, Carrigan PE, Miller LJ. Serine-arginine protein kinase 1 overexpression is associated with tumorigenic imbalance in mitogen-activated protein kinase pathways in breast, colonic, and pancreatic carcinomas. Cancer Res 2007; 67: 2072-2080
-
(2007)
Cancer Res
, vol.67
, pp. 2072-2080
-
-
Hayes, G.M.1
Carrigan, P.E.2
Miller, L.J.3
-
92
-
-
1942533609
-
Identification of two RNA cis-elements that function to regulate the 5' splice site selection of Bcl-x pre-mRNA in response to ceramide
-
Massiello A, Salas A, Pinkerman RL, Roddy P, Roesser JR, Chalfant CE. Identification of two RNA cis-elements that function to regulate the 5' splice site selection of Bcl-x pre-mRNA in response to ceramide. J Biol Chem 2004; 279: 15799-15804
-
(2004)
J Biol Chem
, vol.279
, pp. 15799-15804
-
-
Massiello, A.1
Salas, A.2
Pinkerman, R.L.3
Roddy, P.4
Roesser, J.R.5
Chalfant, C.E.6
-
93
-
-
3042779419
-
S-adenosylmethionine and its metabolite induce apoptosis in HepG2 cells: Role of protein phosphatase 1 and Bcl-x(S)
-
Yang H, Sadda MR, Li M, Zeng Y, Chen L, Bae W, Ou X, Runnegar MT, Mato JM, Lu SC. S-adenosylmethionine and its metabolite induce apoptosis in HepG2 cells: Role of protein phosphatase 1 and Bcl-x(S). Hepatology 2004; 40: 221-231
-
(2004)
Hepatology
, vol.40
, pp. 221-231
-
-
Yang, H.1
Sadda, M.R.2
Li, M.3
Zeng, Y.4
Chen, L.5
Bae, W.6
Ou, X.7
Runnegar, M.T.8
Mato, J.M.9
Lu, S.C.10
-
94
-
-
0036152143
-
S-adenosylmethionine and methylthioadenosine are antiapoptotic in cultured rat hepatocytes but proapoptotic in human hepatoma cells
-
Ansorena E, García-Trevijano ER, Martínez-Chantar ML, Huang ZZ, Chen L, Mato JM, Iraburu M, Lu SC, Avila MA. S-adenosylmethionine and methylthioadenosine are antiapoptotic in cultured rat hepatocytes but proapoptotic in human hepatoma cells. Hepatology 2002; 35: 274-280
-
(2002)
Hepatology
, vol.35
, pp. 274-280
-
-
Ansorena, E.1
García-Trevijano, E.R.2
Martínez-Chantar, M.L.3
Huang, Z.Z.4
Chen, L.5
Mato, J.M.6
Iraburu, M.7
Lu, S.C.8
Avila, M.A.9
-
95
-
-
33646892193
-
Differential regulation of the JNK/AP-1 pathway by S-adenosylmethionine and methylthioadenosine in primary rat hepatocytes versus HuH7 hepatoma cells
-
Ansorena E, Berasain C, López Zabalza MJ, Avila MA, García-Trevijano ER, Iraburu MJ. Differential regulation of the JNK/AP-1 pathway by S-adenosylmethionine and methylthioadenosine in primary rat hepatocytes versus HuH7 hepatoma cells. Am J Physiol Gastrointest Liver Physiol 2006; 290: G1186-G1193
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.290
-
-
Ansorena, E.1
Berasain, C.2
López Zabalza, M.J.3
Avila, M.A.4
García-Trevijano, E.R.5
Iraburu, M.J.6
-
96
-
-
77949519556
-
Restoration of full-length SMN promoted by adenoviral vectors expressing RNA antisense oligonucleotides embedded in U7 snRNAs
-
Geib T, Hertel KJ. Restoration of full-length SMN promoted by adenoviral vectors expressing RNA antisense oligonucleotides embedded in U7 snRNAs. PLoS One 2009; 4: e8204
-
(2009)
PLoS One
, vol.e8204
, pp. 4
-
-
Geib, T.1
Hertel, K.J.2
-
97
-
-
19544363571
-
Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements
-
Bruno IG, Jin W, Cote GJ. Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements. Hum Mol Genet 2004; 13: 2409-2420
-
(2004)
Hum Mol Genet
, vol.13
, pp. 2409-2420
-
-
Bruno, I.G.1
Jin, W.2
Cote, G.J.3
-
98
-
-
33745928141
-
Biological activity and biotechnological aspects of peptide nucleic acid
-
Lundin KE, Good L, Strömberg R, Gräslund A, Smith CI. Biological activity and biotechnological aspects of peptide nucleic acid. Adv Genet 2006; 56: 1-51
-
(2006)
Adv Genet
, vol.56
, pp. 1-51
-
-
Lundin, K.E.1
Good, L.2
Strömberg, R.3
Gräslund, A.4
Smith, C.I.5
-
99
-
-
29144514696
-
Chimeric peptide nucleic acid compounds modulate splicing of the bcl-x gene in vitro and in vivo
-
Wilusz JE, Devanney SC, Caputi M. Chimeric peptide nucleic acid compounds modulate splicing of the bcl-x gene in vitro and in vivo. Nucleic Acids Res 2005; 33: 6547-6554
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 6547-6554
-
-
Wilusz, J.E.1
Devanney, S.C.2
Caputi, M.3
-
100
-
-
0037326836
-
In vivo tumor growth inhibition and biodistribution studies of locked nucleic acid (LNA) antisense oligonucleotides
-
Fluiter K, ten Asbroek AL, de Wissel MB, Jakobs ME, Wissenbach M, Olsson H, Olsen O, Oerum H, Baas F. In vivo tumor growth inhibition and biodistribution studies of locked nucleic acid (LNA) antisense oligonucleotides. Nucleic Acids Res 2003; 31: 953-962
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 953-962
-
-
Fluiter, K.1
ten Asbroek, A.L.2
de Wissel, M.B.3
Jakobs, M.E.4
Wissenbach, M.5
Olsson, H.6
Olsen, O.7
Oerum, H.8
Baas, F.9
-
101
-
-
45749096229
-
An endogenous TNFalpha antagonist induced by splice-switching oligonucleotides reduces inflammation in hepatitis and arthritis mouse models
-
Graziewicz MA, Tarrant TK, Buckley B, Roberts J, Fulton L, Hansen H, Ørum H, Kole R, Sazani P. An endogenous TNFalpha antagonist induced by splice-switching oligonucleotides reduces inflammation in hepatitis and arthritis mouse models. Mol Ther 2008; 16: 1316-1322
-
(2008)
Mol Ther
, vol.16
, pp. 1316-1322
-
-
Graziewicz, M.A.1
Tarrant, T.K.2
Buckley, B.3
Roberts, J.4
Fulton, L.5
Hansen, H.6
ørum, H.7
Kole, R.8
Sazani, P.9
-
102
-
-
69849096670
-
Antisense gapmers selectively suppress individual oncogenic p73 splice isoforms and inhibit tumor growth in vivo
-
Emmrich S, Wang W, John K, Li W, Pützer BM. Antisense gapmers selectively suppress individual oncogenic p73 splice isoforms and inhibit tumor growth in vivo. Mol Cancer 2009; 8: 61
-
(2009)
Mol Cancer
, vol.8
, pp. 61
-
-
Emmrich, S.1
Wang, W.2
John, K.3
Li, W.4
Pützer, B.M.5
-
103
-
-
63849196603
-
Splicing therapeutics in SMN2 and APOB
-
Khoo B, Krainer AR. Splicing therapeutics in SMN2 and APOB. Curr Opin Mol Ther 2009; 11: 108-115
-
(2009)
Curr Opin Mol Ther
, vol.11
, pp. 108-115
-
-
Khoo, B.1
Krainer, A.R.2
-
104
-
-
67650299463
-
Control of alternative splicing through siRNA- mediated transcriptional gene silencing
-
Alló M, Buggiano V, Fededa JP, Petrillo E, Schor I, de la Mata M, Agirre E, Plass M, Eyras E, Elela SA, Klinck R, Chabot B, Kornblihtt AR. Control of alternative splicing through siRNA- mediated transcriptional gene silencing. Nat Struct Mol Biol 2009; 16: 717-724
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 717-724
-
-
Alló, M.1
Buggiano, V.2
Fededa, J.P.3
Petrillo, E.4
Schor, I.5
de la Mata, M.6
Agirre, E.7
Plass, M.8
Eyras, E.9
Elela, S.A.10
Klinck, R.11
Chabot, B.12
Kornblihtt, A.R.13
-
105
-
-
1542269161
-
Progress in antisense technology
-
Crooke ST. Progress in antisense technology. Annu Rev Med 2004; 55: 61-95
-
(2004)
Annu Rev Med
, vol.55
, pp. 61-95
-
-
Crooke, S.T.1
-
106
-
-
76149130971
-
Alternative splicing: Global insights
-
Hallegger M, Llorian M, Smith CW. Alternative splicing: global insights. FEBS J 2010; 277: 856-866
-
(2010)
FEBS J
, vol.277
, pp. 856-866
-
-
Hallegger, M.1
Llorian, M.2
Smith, C.W.3
-
107
-
-
70449723255
-
High resolution analysis of the human transcriptome: Detection of extensive alternative splicing independent of transcriptional activity
-
Zhou W, Calciano MA, Jordan H, Brenner M, Johnson S, Wu D, Lei L, Pallares D, Beurdeley P, Rouet F, Gill PS, Bracco L, Soucaille C, Einstein R. High resolution analysis of the human transcriptome: detection of extensive alternative splicing independent of transcriptional activity. BMC Genet 2009; 10: 63
-
(2009)
BMC Genet
, vol.10
, pp. 63
-
-
Zhou, W.1
Calciano, M.A.2
Jordan, H.3
Brenner, M.4
Johnson, S.5
Wu, D.6
Lei, L.7
Pallares, D.8
Beurdeley, P.9
Rouet, F.10
Gill, P.S.11
Bracco, L.12
Soucaille, C.13
Einstein, R.14
|