Alternative mRNA splicing of liver intestine-cadherin in hepatocellular carcinoma

Clinical Cancer Research

Volumn 11, Issue 2 I, 2005, Pages 483-489

  Wang, Xiao Qi ^a   Luk, John M ^a,c   Leung, Pauline P ^a   Wong, Bonnie W ^a   Stanbridge, Eric J ^b   Fan, Sheung Tat ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

CADHERIN; LI CADHERIN; MESSENGER RNA; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ARTICLE; CANCER INFILTRATION; CANCER RECURRENCE; CANCER SURVIVAL; CONTROLLED STUDY; EXON; GENE EXPRESSION; GENE SEQUENCE; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRON; LIVER CELL CARCINOMA; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SURVIVAL TIME; UPREGULATION;

ALTERNATIVE SPLICING; ANIMALS; BASE SEQUENCE; CADHERINS; CARCINOMA, HEPATOCELLULAR; CERCOPITHECUS AETHIOPS; COS CELLS; EXONS; HUMANS; INTESTINES; LIVER; LIVER NEOPLASMS; MOLECULAR SEQUENCE DATA; NEOPLASM RECURRENCE, LOCAL; POLYMORPHISM, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; SURVIVAL RATE; TRANSFECTION;

EID: 12244254020     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Llovet JM, Burroughs A, Bruix J. Hepatocellular carcinoma. Lancet 2003;362:1907-17.
2. Gessner R, Tauber R. Intestinal cell adhesion molecules. Liver-intestine cadherin. Ann N Y Acad Sci 2000;915:136-43.
3. Becker KF, Atkinson MJ, Reich U, et al. Exon skipping in the E-cadherin gene transcript in metastatic human gastric carcinomas. Hum Mol Genet 1993;2:803-4.
4. Oda T, Kanai Y, Oyama T, et al. E-cadherin gene mutations in human gastric carcinoma cell lines. Proc Natl Acad Sci U S A 1994;91:1858-62.
5. Becker KF, Atkinson MJ, Reich U, et al. E-cadherin gene mutations provide clues to diffuse type gastric carcinomas. Cancer Res 1994;54:3845-52.
6. Smits R, Ruiz P, Diaz-Cano S, et al. E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice. Gastroenterology 2000;119:1045-53.
7. Groden J. Touch and go: mediating cell-to-cell interactions and Wnt signaling in gastrointestinal tumor formation. Gastroenterology 2000;119:1161-4.
8. Kozyraki R, Scoazec JY, Flejou JF, et al. Expression of cadherins and α-catenin in primary epithelial tumors of the liver. Gastroenterology 1996;110:1137-49.
9. Ji X, Woodard AS, Rimm DL, Fearon ER. Transcriptional defects underlie loss of E-cadherin expression in breast cancer. Cell Growth Differ 1997;8:773-8.
10. Hazan RB, Phillips GR, Qiao RF, Norton L, Aaronson SA. Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis. J Cell Biol 2000;148:779-90. Erratum in: J Cell Biol 2000;149:236.
11. Hazan RB, Phillips GR, Qiao RF, Norton L, Aaronson SA. Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis. J Cell Biol 2000;148:779-90. Erratum in: J Cell Biol 2000;149:236.
12. Feltes CM, Kudo A, Blaschuk O, Byers SW. An alternatively spliced cadherin-11 enhances human breast cancer cell invasion. Cancer Res 2002;62:6688-97.
13. Wong BW, Luk JM, Ng IO, et al. Identification of liver-intestine cadherin in hepatocellular carcinoma - a potential disease marker. Biochem Biophys Res Commun 2003;311:618-24.
14. Grotzinger C, Kneifel J, Patschan D, et al. LI-cadherin: a marker of gastric metaplasia and neoplasia. Gut 2001;49:73-81.
15. Ko S, Chu KM, Luk JM, et al. Overexpression of LI-cadherin in gastric cancer is associated with lymph node metastasis. Biochem Biophys Res Commun 2004;319:562-8.
16. Takamura M, Sakamoto M, Ino Y, et al. Expression of liver-intestine cadherin and its possible interaction with galectin-3 in ductal adenocarcinoma of the pancreas. Cancer Sci 2003;94:425-30.
17. Greene FL, Page DL, Fleming ID, et al. AJCC Liver including intrahepatic bile ducts. American Joint Committee on Cancer Staging Manual. 6th ed. New York: Springer; 2002.
18. Luk JM, Mok BW, Shum CK, et al. Identification of novel genes expressed during spermatogenesis in stage-synchronized rat testes by differential display. Biochem Biophys Res Commun 2003;307:782-90.
19. O'Driscoll M, Ruiz-Perez VL, Woods CG, Jeggo PA, Goodship JA. A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome. Nat Genet 2003;33:497-501.
20. Cartegni L, Chew SL, Krainer AR. Listening to silence and understanding nonsense: exonic mutations that affect splicing. Nat Rev Genet 2002;3:285-98.
21. Black DL. Mechanisms of alternative pre-messenger RNA splicing. Annu Rev Biochem 2003;72:291-336.
22. Philips AV, Cooper TA. RNA processing and human disease. Cell Mol Life Sci 2000;57:235-49.
23. Faustino NA, Cooper TA. Pre-mRNA splicing and human diseases. Genes Dev 2003;17:419-37.
24. Kreft B, Bemdorff D, Bottinger A, et al. LI-cadherin-mediated cell-cell adhesion does not require cytoplasmic interactions. J Cell Biol 1997;136:1109-21.
25. Bemdorff D, Gessner R, Kreft B, et al. Liver-intestine cadherin: molecular cloning and characterization of a novel Ca(2+)-dependent cell adhesion molecule expressed in liver and intestine. J Cell Biol 1994;125:1353-69.
26. Lukas J, Gao DQ, Keshmeshian M, et al. Alternative and aberrant messenger RNA splicing of the mdm2 oncogene in invasive breast cancer. Cancer Res 2001;61:3212-9.