Synthesis, structure and anticancer activity of novel alkenyl-1,3,5-triazine derivatives

European Journal of Medicinal Chemistry

Volumn 41, Issue 5, 2006, Pages 611-615

  Saczewski, F ^a   Bulakowska A ^a  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

Author keywords

4 (E) ethenyl 6 alkylamino 1,3,5 triazin 2 ylamines; Antitumor activity; Structure; Synthesis

Indexed keywords

(4 AMINO 6 ALKYLAMINO [1,3,5]TRIAZIN 2 YLMETHYL) TRIPHENYL PHOSPHONIUM,BROMIDE DERIVATIVE; (4 AMINO 6 MORPHOLIN 4 YL [1,3,5]TRIAZIN 2 YLMETHYL) TRIPHENYL PHOSPHONIUM,BROMIDE; (4 AMINO 6 PYRROLIDIN 1 YL [1,3,5]TRIAZIN 2 YLMETHYL) TRIPHENYL PHOSPHONIUM,BROMIDE; 4 [(E) 2 (4 NITROPHENYL)ETHENYL] 6 (4 PHENYLPIPERAZIN 1 YL) 1,3,5 TRIAZIN 2 YLAMINE; 4 [(E) 2 (5 NITRO 2 THIENYL)ETHENYL] 6 (3,5,5 TRIMETHYL 4,5 DIHYDRO 1H PYRAZOLIN 1 YL) 1,3,5 TRIAZIN 2 YLAMINE; 4 [(E) 2 (5 NITRO 2 THIENYL)ETHENYL] 6 (4 PHENYLPIPERAZIN 1 YL) 1,3,5 TRIAZIN 2 YLAMINE; 4 [(E) 2 PHENYLETHENYL] 6 (4 PHENYLPIPERAZIN 1 YL) 1,3,5 TRIAZIN 2 YLAMINE; 4 [(E) 2 PHENYLETHENYL] 6 PYRROLIDIN 1 YL 1,3,5 TRIAZIN 2 YLAMINE; 6 [(E) 2 (5 NITRO 2 THIOPHENYL)ETHENYL] 4( MORPHOLIN 4 YL) 1,3,5 TRIAZIN 2 YLAMINE; [4 AMINO 6 (3,5,5 TRIMETHYL 4,5 DIHYDRO PYRAZOL 1 YL) [1,3,5]TRIAZIN 2 YLMETHYL] TRIPHENYL PHOSPHONIUM,BROMIDE; [4 AMINO 6 (4 PHENYLPIPERAZIN 1 YL) [1,3,5]TRIAZIN 2 YLMETHYL] TRIPHENYL PHOSPHONIUM,BROMIDE; ALKENYL 1,3,5 TRIAZINE DERIVATIVE; ANTINEOPLASTIC AGENT; UNCLASSIFIED DRUG; ALKENE; TRIAZINE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG INHIBITION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GROWTH INHIBITION; HEALTH CARE ORGANIZATION; HUMAN; HUMAN CELL; KIDNEY CANCER; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; WITTIG REACTION; CHEMICAL STRUCTURE; CHEMISTRY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

ALKENES; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG EVALUATION, PRECLINICAL; HUMANS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZINES;

EID: 33646771785     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2005.12.012     Document Type: Article

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