Design, synthesis, and antiviral activity of α-nucleosides: D- and L- isomers of lyxofuranosyl- and (5-deoxylyxofuranosyl)benzimidazoles

Journal of Medicinal Chemistry

Volumn 41, Issue 8, 1998, Pages 1242-1251

  Migawa, Michael T ^c   Girardet, Jean Luc ^c   Walker II, John A ^a   Koszalka, George W ^b   Chamberlain, Stanley D ^b   Drach, John C ^c   Townsend, Leroy B ^c  

^a ProtoGene Laboratories Inc   (United States)

^b GLAXOSMITHKLINE   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

(5 DEOXYLYXOFURANOSYL)BENZIMIDAZOLE DERIVATIVE; ANTIVIRUS AGENT; BENZIMIDAVIR; FOSCARNET; GANCICLOVIR; LYXOFURANOSYL BENZIMIDAZOLE DERIVATIVE; NUCLEOSIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG SPECIFICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; ISOMER; VIRUS CULTURE; VIRUS STRAIN;

ANTIVIRAL AGENTS; BENZIMIDAZOLES; CELL DIVISION; CELL SURVIVAL; CYTOMEGALOVIRUS; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROBLASTS; HERPESVIRUS 1, HUMAN; HUMANS; KB CELLS; MICROBIAL SENSITIVITY TESTS; NUCLEOSIDES; PENTOSES; PLAQUE ASSAY; SKIN; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032499278     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970545c     Document Type: Article

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46. Unpublished data from our laboratory.
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