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Volumn 29, Issue 26, 2010, Pages 3781-3792

A transcriptional cross-talk between RhoA and c-Myc inhibits the RhoA/Rock-dependent cytoskeleton

Author keywords

c Myc; gene expression; integrin; Pak; RhoA; stress fibers

Indexed keywords

BETA INTEGRIN; F ACTIN; P21 ACTIVATED KINASE 1; PROTEIN CDC42; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 77954244629     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.134     Document Type: Article
Times cited : (26)

References (30)
  • 1
    • 0031048791 scopus 로고    scopus 로고
    • Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase
    • Amano M, Chihara K, Kimura K, Fukata Y, Nakamura N, Matsuura Y et al. (1997). Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase. Science 275: 1308-1311.
    • (1997) Science , vol.275 , pp. 1308-1311
    • Amano, M.1    Chihara, K.2    Kimura, K.3    Fukata, Y.4    Nakamura, N.5    Matsuura, Y.6
  • 3
    • 34250893239 scopus 로고    scopus 로고
    • Transcriptomal profiling of the cellular transformation induced by Rho subfamily GTPases
    • Berenjeno IM, Nunez F, Bustelo XR. (2007). Transcriptomal profiling of the cellular transformation induced by Rho subfamily GTPases. Oncogene 26: 4295-4305.
    • (2007) Oncogene , vol.26 , pp. 4295-4305
    • Berenjeno, I.M.1    Nunez, F.2    Bustelo, X.R.3
  • 4
    • 34249018367 scopus 로고    scopus 로고
    • GEFs and GAPs: Critical elements in the control of small G proteins
    • Bos JL, Rehmann H, Wittinghofer A. (2007). GEFs and GAPs: critical elements in the control of small G proteins. Cell 129: 865-877.
    • (2007) Cell , vol.129 , pp. 865-877
    • Bos, J.L.1    Rehmann, H.2    Wittinghofer, A.3
  • 5
    • 34247175312 scopus 로고    scopus 로고
    • GTP-binding proteins of the Rho/Rac family: Regulation, effectors and functions in vivo
    • Bustelo XR, Sauzeau V, Berenjeno IM. (2007). GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo. Bioessays 29: 356-370.
    • (2007) Bioessays , vol.29 , pp. 356-370
    • Bustelo, X.R.1    Sauzeau, V.2    Berenjeno, I.M.3
  • 6
    • 10844230332 scopus 로고    scopus 로고
    • Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis
    • Croft DR, Sahai E, Mavria G, Li S, Tsai J, Lee WM et al. (2004). Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis. Cancer Res 64: 8994-9001.
    • (2004) Cancer Res , vol.64 , pp. 8994-9001
    • Croft, D.R.1    Sahai, E.2    Mavria, G.3    Li, S.4    Tsai, J.5    Lee, W.M.6
  • 7
    • 26944440432 scopus 로고    scopus 로고
    • RhoGDIs revisited: Novel roles in Rho regulation
    • Dransart E, Olofsson B, Cherfils J. (2005). RhoGDIs revisited: novel roles in Rho regulation. Traffic 6: 957-966.
    • (2005) Traffic , vol.6 , pp. 957-966
    • Dransart, E.1    Olofsson, B.2    Cherfils, J.3
  • 8
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • Etienne-Manneville S, Hall A. (2002). Rho GTPases in cell biology. Nature 420: 629-635.
    • (2002) Nature , vol.420 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 9
    • 3342893272 scopus 로고    scopus 로고
    • Rho family GTPases cooperate with p53 deletion to promote primary mouse embryonic fibroblast cell invasion
    • Guo F, Zheng Y. (2004). Rho family GTPases cooperate with p53 deletion to promote primary mouse embryonic fibroblast cell invasion. Oncogene 23: 5577-5585.
    • (2004) Oncogene , vol.23 , pp. 5577-5585
    • Guo, F.1    Zheng, Y.2
  • 10
    • 34247209153 scopus 로고    scopus 로고
    • Gem associates with Ezrin and acts via the Rho-GAP protein Gmip to down-regulate the Rho pathway
    • Hatzoglou A, Ader I, Splingard A, Flanders J, Saade E, Leroy I et al. (2007). Gem associates with Ezrin and acts via the Rho-GAP protein Gmip to down-regulate the Rho pathway. Mol Biol Cell 18: 1242-1252.
    • (2007) Mol Biol Cell , vol.18 , pp. 1242-1252
    • Hatzoglou, A.1    Ader, I.2    Splingard, A.3    Flanders, J.4    Saade, E.5    Leroy, I.6
  • 11
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: Biochemistry and biology
    • Jaffe AB, Hall A. (2005). Rho GTPases: biochemistry and biology. Annu Rev Cell Dev Biol 21: 247-269.
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 12
    • 0029802561 scopus 로고    scopus 로고
    • RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase
    • Joneson T, McDonough M, Bar-Sagi D, Van Aelst L. (1996). RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase. Science 274: 1374-1376.
    • (1996) Science , vol.274 , pp. 1374-1376
    • Joneson, T.1    McDonough, M.2    Bar-Sagi, D.3    Van Aelst, L.4
  • 13
    • 9444242736 scopus 로고    scopus 로고
    • Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase
    • Kimura K, Ito M, Amano M, Chihara K, Fukata Y, Nakafuku M et al. (1996). Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science 273: 245-248.
    • (1996) Science , vol.273 , pp. 245-248
    • Kimura, K.1    Ito, M.2    Amano, M.3    Chihara, K.4    Fukata, Y.5    Nakafuku, M.6
  • 14
    • 45349107819 scopus 로고    scopus 로고
    • Regulation of RhoA-dependent ROCKII activation by Shp2
    • Lee HH, Chang ZF. (2008). Regulation of RhoA-dependent ROCKII activation by Shp2. J Cell Biol 181: 999-1012.
    • (2008) J Cell Biol , vol.181 , pp. 999-1012
    • Lee, H.H.1    Chang, Z.F.2
  • 15
    • 0347717882 scopus 로고    scopus 로고
    • Cytoplasmic p21Cip1 is involved in Ras-induced inhibition of the ROCK/LIMK/cofilin pathway
    • Lee S, Helfman DM. (2004). Cytoplasmic p21Cip1 is involved in Ras-induced inhibition of the ROCK/LIMK/cofilin pathway. J Biol Chem 279: 1885-1891.
    • (2004) J Biol Chem , vol.279 , pp. 1885-1891
    • Lee, S.1    Helfman, D.M.2
  • 16
    • 0031260578 scopus 로고    scopus 로고
    • A novel Cdc42Hs mutant induces cellular transformation
    • Lin R, Bagrodia S, Cerione R, Manor D. (1997). A novel Cdc42Hs mutant induces cellular transformation. Curr Biol 7: 794-797.
    • (1997) Curr Biol , vol.7 , pp. 794-797
    • Lin, R.1    Bagrodia, S.2    Cerione, R.3    Manor, D.4
  • 17
    • 18944372230 scopus 로고    scopus 로고
    • Rho kinase, a promising drug target for neurological disorders
    • Mueller BK, Mack H, Teusch N. (2005). Rho kinase, a promising drug target for neurological disorders. Nat Rev Drug Discov 4: 387-398.
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 387-398
    • Mueller, B.K.1    MacK, H.2    Teusch, N.3
  • 18
    • 0032784388 scopus 로고    scopus 로고
    • Distinct actions and cooperative roles of ROCK and mDia in Rho small G protein-induced reorganization of the actin cytoskeleton in Madin-Darby canine kidney cells
    • Nakano K, Takaishi K, Kodama A, Mammoto A, Shiozaki H, Monden M et al. (1999). Distinct actions and cooperative roles of ROCK and mDia in Rho small G protein-induced reorganization of the actin cytoskeleton in Madin-Darby canine kidney cells. Mol Biol Cell 10: 2481-2491.
    • (1999) Mol Biol Cell , vol.10 , pp. 2481-2491
    • Nakano, K.1    Takaishi, K.2    Kodama, A.3    Mammoto, A.4    Shiozaki, H.5    Monden, M.6
  • 19
    • 0033058184 scopus 로고    scopus 로고
    • Rho guanine dissociation inhibitors: Pivotal molecules in cellular signalling
    • Olofsson B. (1999). Rho guanine dissociation inhibitors: pivotal molecules in cellular signalling. Cell Signal 11: 545-554.
    • (1999) Cell Signal , vol.11 , pp. 545-554
    • Olofsson, B.1
  • 20
    • 33845420563 scopus 로고    scopus 로고
    • RhoE is a pro-survival p53 target gene that inhibits ROCK I-mediated apoptosis in response to genotoxic stress
    • Ongusaha PP, Kim HG, Boswell SA, Ridley AJ, Der CJ, Dotto GP et al. (2006). RhoE is a pro-survival p53 target gene that inhibits ROCK I-mediated apoptosis in response to genotoxic stress. Curr Biol 16: 2466-2472.
    • (2006) Curr Biol , vol.16 , pp. 2466-2472
    • Ongusaha, P.P.1    Kim, H.G.2    Boswell, S.A.3    Ridley, A.J.4    Der Dotto, G.P.5
  • 23
    • 0038024241 scopus 로고    scopus 로고
    • Rocks: Multifunctional kinases in cell behaviour
    • Riento K, Ridley AJ. (2003). Rocks: multifunctional kinases in cell behaviour. Nat Rev Cell Biol 4: 446-456.
    • (2003) Nat Rev Cell Biol , vol.4 , pp. 446-456
    • Riento, K.1    Ridley, A.J.2
  • 24
    • 33846014269 scopus 로고    scopus 로고
    • Smurf1 regulates tumor cell plasticity and motility through degradation of RhoA leading to localized inhibition of contractility
    • Sahai E, Garcia-Medina R, Pouyssegur J, Vial E. (2007). Smurf1 regulates tumor cell plasticity and motility through degradation of RhoA leading to localized inhibition of contractility. J Cell Biol 176: 35-42.
    • (2007) J Cell Biol , vol.176 , pp. 35-42
    • Sahai, E.1    Garcia-Medina, R.2    Pouyssegur, J.3    Vial, E.4
  • 25
    • 0033545354 scopus 로고    scopus 로고
    • Transformation mediated by RhoA requires activity of ROCK kinases
    • Sahai E, Ishizaki T, Narumiya S, Treisman R. (1999). Transformation mediated by RhoA requires activity of ROCK kinases. Curr Biol 9: 136-145.
    • (1999) Curr Biol , vol.9 , pp. 136-145
    • Sahai, E.1    Ishizaki, T.2    Narumiya, S.3    Treisman, R.4
  • 28
    • 0344758986 scopus 로고    scopus 로고
    • Regulation of cell polarity and protrusion formation by targeting RhoA for degradation
    • Wang HR, Zhang Y, Ozdamar B, Ogunjimi AA, Alexandrova E, Thomsen GH et al. (2003). Regulation of cell polarity and protrusion formation by targeting RhoA for degradation. Science 302: 1775-1779.
    • (2003) Science , vol.302 , pp. 1775-1779
    • Wang, H.R.1    Zhang, Y.2    Ozdamar, B.3    Ogunjimi, A.A.4    Alexandrova, E.5    Thomsen, G.H.6
  • 29
    • 0037092045 scopus 로고    scopus 로고
    • The GTP binding proteins Gem and Rad are negative regulators of the Rho-Rho kinase pathway
    • Ward Y, Yap SF, Ravichandran V, Matsumura F, Ito M, Spinelli B et al. (2002). The GTP binding proteins Gem and Rad are negative regulators of the Rho-Rho kinase pathway. J Cell Biol 157: 291-302.
    • (2002) J Cell Biol , vol.157 , pp. 291-302
    • Ward, Y.1    Yap, S.F.2    Ravichandran, V.3    Matsumura, F.4    Ito, M.5    Spinelli, B.6
  • 30
    • 0042972556 scopus 로고    scopus 로고
    • Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis
    • Watnick RS, Cheng YN, Rangarajan A, Ince TA, Weinberg RA. (2003). Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis. Cancer Cell 3: 219-231.
    • (2003) Cancer Cell , vol.3 , pp. 219-231
    • Watnick, R.S.1    Cheng, Y.N.2    Rangarajan, A.3    Ince, T.A.4    Weinberg, R.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.