SCOPUS 정보 검색 플랫폼

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 13, 2010, Pages 4615-4624

Discovery of novel purine derivatives with potent and selective inhibitory activity against c-Src tyrosine kinase

(7) Huang, He a Ma, Jingui a Shi, Jianmei a Meng, Linghua a Jiang, Hualiang a Ding, Jian a Liu, Hong a

a SHANGHAI INSTITUTE OF MATERIA MEDICA (China)

Author keywords

c Src tyrosine kinase; Focused library; Inhibitor; Purine derivative

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; N (3 AMINOSULFONYLPHENYL) 2 (PIPERAZIN 1 YL) 9H PURIN 6 AMINE; N (3 AMINOSULFONYLPHENYL) 2 MORPHOLINO 9H PURIN 6 AMINE; N (3 METHOXYPHENYL) 2 (PIPERAZIN 1 YL) 9H PURIN 6 AMINE; N (3 METHOXYPHENYL) 2 [4 (2 HYDROXYETHYL)PIPERAZIN 1 YL] 9H PURIN 6 AMINE; N (3 METHOXYPHENYL) 2 MORPHOLINO 9H PURIN 6 AMINE; N (3 METHYLPHENYL) 2 [4 (2 HYDROXYETHYL)PIPERAZIN 1 YL] 9H PURIN 6 AMINE; N (3 METHYLPHENYL) 2 MORPHOLINO 9H PURIN 6 AMINE; N (3 NITROPHENYL) 2 MORPHOLINO 9H PURIN 6 AMINE; N (3 NITROXYPHENYL) 2 (PIPERAZIN 1 YL) 9H PURIN 6 AMINE; N (4 ACETAMIDOPHENYL) 2 (PIPERAZIN 1 YL) 9H PURIN 6 AMINE; N (4 ACETAMIDOPHENYL) 2 MORPHOLINO 9H PURIN 6 AMINE; N (4 AMINOSULFONYLPHENYL) 2 (PIPERAZIN 1 YL) 9H PURIN 6 AMINE; N (4 AMINOSULFONYLPHENYL) 2 MORPHOLINO 9H PURIN 6 AMINE; N (4 BROMOPHENYL) 2 (PIPERAZIN 1 YL) 9H PURIN 6 AMINE; N (4 BROMOPHENYL) 2 MORPHOLINO 9H PURIN 6 AMINE; N (4 CARBAMOYLPHENYL) 2 (PIPERAZIN 1 YL) 9H PURIN 6 AMINE; N (4 CARBAMOYLPHENYL) 2 MORPHOLINO 9H PURIN 6 AMINE; N (4 CHLOROPHENYL) 2 (PIPERAZIN 1 YL) 9H PURIN 6 AMINE; N (4 CHLOROPHENYL) 2 [4 (2 HYDROXYETHYL)PIPERAZIN 1 YL] 9H PURIN 6 AMINE; N (4 CHLOROPHENYL) 2 MORPHOLINO 9H PURIN 6 AMINE; N (4 METHOXYPHENYL) 2 [4 (2 HYDROXYETHYL)PIPERAZIN 1 YL] 9H PURIN 6 AMINE; N (4 METHOXYPHENYL) 2 MORPHOLINO 9H PURIN 6 AMINE; N (4 NITROPHENYL) 2 MORPHOLINO 9H PURIN 6 AMINE; N (4 NITROXYPHENYL) 2 (PIPERAZIN 1 YL) 9H PURIN 6 AMINE; N PHENYL 2 [4 (2 HYDROXYETHYL)PIPERAZIN 1 YL] 9H PURIN 6 AMINE; N PHENYL 2 MORPHOLINO 9H PURIN 6 AMINE; PROTEIN TYROSINE KINASE INHIBITOR; PURINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; COMBINATORIAL LIBRARY; CONTROLLED STUDY; DRUG POTENCY; DRUG SCREENING; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC 50; MOLECULAR DOCKING; SIMULATION; STRUCTURE ACTIVITY RELATION;

BINDING SITES; CELL LINE, TUMOR; CELL MOVEMENT; COMPUTER SIMULATION; DRUG EVALUATION, PRECLINICAL; HUMANS; MORPHOLINES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PURINES; SRC-FAMILY KINASES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77954213519 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/j.bmc.2010.05.032 Document Type: Article

Times cited : (26)

References (41)

1
- 0035374609
- G.S. Martin Nat. Rev. Mol. Cell Biol. 2 2001 467
- (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , pp. 467
- Martin, G.S.¹

2
- 2942618768
- T.J. Yeatman Nat. Rev. Cancer 4 2004 470
- (2004) Nat. Rev. Cancer , vol.4 , pp. 470
- Yeatman, T.J.¹

3
- 48749118203
- R.S. Finn Ann. Oncol. 19 2008 1379
- (2008) Ann. Oncol. , vol.19 , pp. 1379
- Finn, R.S.¹

4
- 0038386613
- J.M. Summy, and G.E. Gallick Cancer Metastasis Rev. 22 2003 337
- (2003) Cancer Metastasis Rev. , vol.22 , pp. 337
- Summy, J.M.¹ Gallick, G.E.²

5
- 0037150728
- M.C. Frame Biochim. Biophys. Acta 1602 2002 114
- (2002) Biochim. Biophys. Acta , vol.1602 , pp. 114
- Frame, M.C.¹

6
- 33645072205
- J.M. Summy, and G.E. Gallick Clin. Cancer Res. 12 2006 1398
- (2006) Clin. Cancer Res. , vol.12 , pp. 1398
- Summy, J.M.¹ Gallick, G.E.²

7
- 43549113396
- N. Rucci, M. Susa, and A. Teti Anticancer Agents Med. Chem. 8 2008 342
- (2008) Anticancer Agents Med. Chem. , vol.8 , pp. 342
- Rucci, N.¹ Susa, M.² Teti, A.³

8
- 38449114562
- A. Hilbig Recent Results Cancer Res. 177 2008 179
- (2008) Recent Results Cancer Res. , vol.177 , pp. 179
- Hilbig, A.¹

9
- 33750713666
- B.F. Boyce, L. Xing, Z. Yao, T. Yamashita, W.C. Shakespeare, Y. Wang, C.A. Metcalf III, R. Sundaramoorthi, D.C. Dalgarno, J.D. Iuliucci, and T.K. Sawyer Clin. Cancer Res. 12 2006 6291s
- (2006) Clin. Cancer Res. , vol.12
- Boyce, B.F.¹ Xing, L.² Yao, Z.³ Yamashita, T.⁴ Shakespeare, W.C.⁵ Wang, Y.⁶ Metcalf Iii, C.A.⁷ Sundaramoorthi, R.⁸ Dalgarno, D.C.⁹ Iuliucci, J.D.¹⁰ Sawyer, T.K.¹¹

10
- 44849134528
- S.I. Park, J. Zhang, K.A. Phillips, J.C. Araujo, A.M. Najjar, A.Y. Volgin, J.G. Gelovani, S.J. Kim, Z. Wang, and G.E. Gallick Cancer Res. 68 2008 3323
- (2008) Cancer Res. , vol.68 , pp. 3323
- Park, S.I.¹ Zhang, J.² Phillips, K.A.³ Araujo, J.C.⁴ Najjar, A.M.⁵ Volgin, A.Y.⁶ Gelovani, J.G.⁷ Kim, S.J.⁸ Wang, Z.⁹ Gallick, G.E.¹⁰

11
- 19944428353
- L.J. Lombardo, F.Y. Lee, P. Chen, D. Norris, J.C. Barrish, K. Behnia, S. Castaneda, L.A. Cornelius, J. Das, A.M. Doweyko, C. Fairchild, J.T. Hunt, I. Inigo, K. Johnston, A. Kamath, D. Kan, H. Klei, P. Marathe, S. Pang, R. Peterson, S. Pitt, G.L. Schieven, R.J. Schmidt, J. Tokarski, M.L. Wen, J. Wityak, and R.M. Borzilleri J. Med. Chem. 47 2004 6658
- (2004) J. Med. Chem. , vol.47 , pp. 6658
- Lombardo, L.J.¹ Lee, F.Y.² Chen, P.³ Norris, D.⁴ Barrish, J.C.⁵ Behnia, K.⁶ Castaneda, S.⁷ Cornelius, L.A.⁸ Das, J.⁹ Doweyko, A.M.¹⁰ Fairchild, C.¹¹ Hunt, J.T.¹² Inigo, I.¹³ Johnston, K.¹⁴ Kamath, A.¹⁵ Kan, D.¹⁶ Klei, H.¹⁷ Marathe, P.¹⁸ Pang, S.¹⁹ Peterson, R.²⁰ more..

12
- 33750989362
- J. Das, P. Chen, D. Norris, R. Padmanabha, J. Lin, R.V. Moquin, Z. Shen, L.S. Cook, A.M. Doweyko, S. Pitt, S. Pang, D.R. Shen, Q. Fang, H.F. de Fex, K.W. McIntyre, D.J. Shuster, K.M. Gillooly, K. Behnia, G.L. Schieven, J. Wityak, and J.C. Barrish J. Med. Chem. 49 2006 6819
- (2006) J. Med. Chem. , vol.49 , pp. 6819
- Das, J.¹ Chen, P.² Norris, D.³ Padmanabha, R.⁴ Lin, J.⁵ Moquin, R.V.⁶ Shen, Z.⁷ Cook, L.S.⁸ Doweyko, A.M.⁹ Pitt, S.¹⁰ Pang, S.¹¹ Shen, D.R.¹² Fang, Q.¹³ De Fex, H.F.¹⁴ McIntyre, K.W.¹⁵ Shuster, D.J.¹⁶ Gillooly, K.M.¹⁷ Behnia, K.¹⁸ Schieven, G.L.¹⁹ Wityak, J.²⁰ Barrish, J.C.²¹ more..

13
- 60149091984
- B. Serrels, A. Serrels, S.M. Mason, C. Baldeschi, G.H. Ashton, M. Canel, L.J. Mackintosh, B. Doyle, T.P. Green, M.C. Frame, O.J. Sansom, and V.G. Brunton Carcinogenesis 30 2009 249
- (2009) Carcinogenesis , vol.30 , pp. 249
- Serrels, B.¹ Serrels, A.² Mason, S.M.³ Baldeschi, C.⁴ Ashton, G.H.⁵ Canel, M.⁶ MacKintosh, L.J.⁷ Doyle, B.⁸ Green, T.P.⁹ Frame, M.C.¹⁰ Sansom, O.J.¹¹ Brunton, V.G.¹²

14
- 68549115413
- W.S. Huang, X. Zhu, Y. Wang, M. Azam, D. Wen, R. Sundaramoorthi, R.M. Thomas, S. Liu, G. Banda, S.P. Lentini, S. Das, Q. Xu, J. Keats, F. Wang, S. Wardwell, Y. Ning, J.T. Snodgrass, M.I. Broudy, K. Russian, G.Q. Daley, J. Iuliucci, D.C. Dalgarno, T. Clackson, T.K. Sawyer, and W.C. Shakespeare J. Med. Chem. 52 2009 4743
- (2009) J. Med. Chem. , vol.52 , pp. 4743
- Huang, W.S.¹ Zhu, X.² Wang, Y.³ Azam, M.⁴ Wen, D.⁵ Sundaramoorthi, R.⁶ Thomas, R.M.⁷ Liu, S.⁸ Banda, G.⁹ Lentini, S.P.¹⁰ Das, S.¹¹ Xu, Q.¹² Keats, J.¹³ Wang, F.¹⁴ Wardwell, S.¹⁵ Ning, Y.¹⁶ Snodgrass, J.T.¹⁷ Broudy, M.I.¹⁸ Russian, K.¹⁹ Daley, G.Q.²⁰ more..

15
- 67849128649
- J. Homsi, C.L. Cubitt, S. Zhang, P.N. Munster, H. Yu, D.M. Sullivan, R. Jove, J.L. Messina, and A.I. Daud Melanoma Res. 19 2009 167
- (2009) Melanoma Res. , vol.19 , pp. 167
- Homsi, J.¹ Cubitt, C.L.² Zhang, S.³ Munster, P.N.⁴ Yu, H.⁵ Sullivan, D.M.⁶ Jove, R.⁷ Messina, J.L.⁸ Daud, A.I.⁹

16
- 70350072332
- K. Lafleur, D. Huang, T. Zhou, A. Caflisch, and C. Nevado J. Med. Chem. 52 2009 6433
- (2009) J. Med. Chem. , vol.52 , pp. 6433
- Lafleur, K.¹ Huang, D.² Zhou, T.³ Caflisch, A.⁴ Nevado, C.⁵

17
- 64249107125
- K. Lee, J. Kim, K.W. Jeong, K.W. Lee, Y. Lee, J.Y. Song, M.S. Kim, G.S. Lee, and Y. Kim Bioorg. Med. Chem. 17 2009 3152
- (2009) Bioorg. Med. Chem. , vol.17 , pp. 3152
- Lee, K.¹ Kim, J.² Jeong, K.W.³ Lee, K.W.⁴ Lee, Y.⁵ Song, J.Y.⁶ Kim, M.S.⁷ Lee, G.S.⁸ Kim, Y.⁹

18
- 77950861650
- D.H. Boschelli, D. Wang, Y. Wang, B. Wu, E.E. Honores, A.C. Barrios Sosa, I. Chaudhary, J. Golas, J. Lucas, and F. Boschelli Bioorg. Med. Chem. Lett. 20 2010 2924
- (2010) Bioorg. Med. Chem. Lett. , vol.20 , pp. 2924
- Boschelli, D.H.¹ Wang, D.² Wang, Y.³ Wu, B.⁴ Honores, E.E.⁵ Barrios Sosa, A.C.⁶ Chaudhary, I.⁷ Golas, J.⁸ Lucas, J.⁹ Boschelli, F.¹⁰

19
- 33745080292
- D. Dalgarno, T. Stehle, S. Narula, P. Schelling, M.R. van Schravendijk, S. Adams, L. Andrade, J. Keats, M. Ram, L. Jin, T. Grossman, I. MacNeil, C. Metcalf III, W. Shakespeare, Y. Wang, T. Keenan, R. Sundaramoorthi, R. Bohacek, M. Weigele, and T. Sawyer Chem. Biol. Drug Des. 67 2006 46
- (2006) Chem. Biol. Drug Des. , vol.67 , pp. 46
- Dalgarno, D.¹ Stehle, T.² Narula, S.³ Schelling, P.⁴ Van Schravendijk, M.R.⁵ Adams, S.⁶ Andrade, L.⁷ Keats, J.⁸ Ram, M.⁹ Jin, L.¹⁰ Grossman, T.¹¹ MacNeil, I.¹² Metcalf Iii, C.¹³ Shakespeare, W.¹⁴ Wang, Y.¹⁵ Keenan, T.¹⁶ Sundaramoorthi, R.¹⁷ Bohacek, R.¹⁸ Weigele, M.¹⁹ Sawyer, T.²⁰ more..

20
- 12444268973
- Y. Wang, C.A. Metcalf III, W.C. Shakespeare, R. Sundaramoorthi, T.P. Keenan, R.S. Bohacek, M.R. van Schravendijk, S.M. Violette, S.S. Narula, D.C. Dalgarno, C. Haraldson, J. Keats, S. Liou, U. Mani, S. Pradeepan, M. Ram, S. Adams, M. Weigele, and T.K. Sawyer Bioorg. Med. Chem. Lett. 13 2003 3067
- (2003) Bioorg. Med. Chem. Lett. , vol.13 , pp. 3067
- Wang, Y.¹ Metcalf Iii, C.A.² Shakespeare, W.C.³ Sundaramoorthi, R.⁴ Keenan, T.P.⁵ Bohacek, R.S.⁶ Van Schravendijk, M.R.⁷ Violette, S.M.⁸ Narula, S.S.⁹ Dalgarno, D.C.¹⁰ Haraldson, C.¹¹ Keats, J.¹² Liou, S.¹³ Mani, U.¹⁴ Pradeepan, S.¹⁵ Ram, M.¹⁶ Adams, S.¹⁷ Weigele, M.¹⁸ Sawyer, T.K.¹⁹

21
- 33746827430
- M. Legraverend, and D.S. Grierson Bioorg. Med. Chem. 14 2006 3987
- (2006) Bioorg. Med. Chem. , vol.14 , pp. 3987
- Legraverend, M.¹ Grierson, D.S.²

22
- 0035924176
- Y.T. Chang, S.M. Wignall, G.R. Rosania, N.S. Gray, S.R. Hanson, A.I. Su, J. Merlie Jr., H.S. Moon, S.B. Sangankar, O. Perez, R. Heald, and P.G. Schultz J. Med. Chem. 44 2001 4497
- (2001) J. Med. Chem. , vol.44 , pp. 4497
- Chang, Y.T.¹ Wignall, S.M.² Rosania, G.R.³ Gray, N.S.⁴ Hanson, S.R.⁵ Su, A.I.⁶ Merlie Jr., J.⁷ Moon, H.S.⁸ Sangankar, S.B.⁹ Perez, O.¹⁰ Heald, R.¹¹ Schultz, P.G.¹²

23
- 0035071607
- G. Chiosis, M.N. Timaul, B. Lucas, P.N. Munster, F.F. Zheng, L. Sepp-Lorenzino, and N. Rosen Chem. Biol. 8 2001 289
- (2001) Chem. Biol. , vol.8 , pp. 289
- Chiosis, G.¹ Timaul, M.N.² Lucas, B.³ Munster, P.N.⁴ Zheng, F.F.⁵ Sepp-Lorenzino, L.⁶ Rosen, N.⁷

24
- 0037075792
- L.L. Gundersen, J. Nissen-Meyer, and B. Spilsberg J. Med. Chem. 45 2002 1383
- (2002) J. Med. Chem. , vol.45 , pp. 1383
- Gundersen, L.L.¹ Nissen-Meyer, J.² Spilsberg, B.³

25
- 0037463772
- T.D. Penning, N.S. Chandrakumar, B.N. Desai, S.W. Djuric, A.F. Gasiecki, J.W. Malecha, J.M. Miyashiro, M.A. Russell, L.J. Askonas, J.K. Gierse, E.I. Harding, M.K. Highkin, J.F. Kachur, S.H. Kim, D. Villani-Price, E.Y. Pyla, N.S. Ghoreishi-Haack, and W.G. Smith Bioorg. Med. Chem. Lett. 13 2003 1137
- (2003) Bioorg. Med. Chem. Lett. , vol.13 , pp. 1137
- Penning, T.D.¹ Chandrakumar, N.S.² Desai, B.N.³ Djuric, S.W.⁴ Gasiecki, A.F.⁵ Malecha, J.W.⁶ Miyashiro, J.M.⁷ Russell, M.A.⁸ Askonas, L.J.⁹ Gierse, J.K.¹⁰ Harding, E.I.¹¹ Highkin, M.K.¹² Kachur, J.F.¹³ Kim, S.H.¹⁴ Villani-Price, D.¹⁵ Pyla, E.Y.¹⁶ Ghoreishi-Haack, N.S.¹⁷ Smith, W.G.¹⁸

26
- 0037065313
- E. Chapman, S. Ding, P.G. Schultz, and C.H. Wong J. Am. Chem. Soc. 124 2002 14524
- (2002) J. Am. Chem. Soc. , vol.124 , pp. 14524
- Chapman, E.¹ Ding, S.² Schultz, P.G.³ Wong, C.H.⁴

27
- 8644276353
- E. Altmann, S.W. Cowan-Jacob, and M. Missbach J. Med. Chem. 47 2004 5833
- (2004) J. Med. Chem. , vol.47 , pp. 5833
- Altmann, E.¹ Cowan-Jacob, S.W.² Missbach, M.³

28
- 0037293780
- P. Raboisson, C. Lugnier, C. Muller, J.M. Reimund, D. Schultz, G. Pinna, A. Le Bec, H. Basaran, L. Desaubry, F. Gaudiot, M. Seloum, and J.J. Bourguignon Eur. J. Med. Chem. 38 2003 199
- (2003) Eur. J. Med. Chem. , vol.38 , pp. 199
- Raboisson, P.¹ Lugnier, C.² Muller, C.³ Reimund, J.M.⁴ Schultz, D.⁵ Pinna, G.⁶ Le Bec, A.⁷ Basaran, H.⁸ Desaubry, L.⁹ Gaudiot, F.¹⁰ Seloum, M.¹¹ Bourguignon, J.J.¹²

29
- 6044239448
- P.G. Baraldi, F. Fruttarolo, M.A. Tabrizi, R. Romagnoli, D. Preti, A. Bovero, M.J. Pineda de Las Infantas, A. Moorman, K. Varani, and P.A. Borea J. Med. Chem. 47 2004 5535
- (2004) J. Med. Chem. , vol.47 , pp. 5535
- Baraldi, P.G.¹ Fruttarolo, F.² Tabrizi, M.A.³ Romagnoli, R.⁴ Preti, D.⁵ Bovero, A.⁶ Pineda De Las Infantas, M.J.⁷ Moorman, A.⁸ Varani, K.⁹ Borea, P.A.¹⁰

30
- 77954215313
- Patent WO2005016528
- Cheng, D.; Ding, Q.; Han, D.; Gray, N. S.; Zhang, G.; Dai, C.; Dong, H.; Guo, B. Z.; Qiang, D.; Schiander, G. N.; Gray, M. S. Patent WO2005016528, 2005
- (2005)
- Cheng, D.¹ Ding, Q.² Han, D.³ Gray, N.S.⁴ Zhang, G.⁵ Dai, C.⁶ Dong, H.⁷ Guo, B.Z.⁸ Qiang, D.⁹ Schiander, G.N.¹⁰ Gray, M.S.¹¹

31
- 77954218700
- Chem. Abstr. 2005, 142, 261551.
- (2005) Chem. Abstr. , vol.142 , pp. 261551

32
- 77954214028
- Patent WO2008094737
- Winzeler, E.; Gray, N. S.; Han, D.; Cheng, D. Patent WO2008094737, 2008
- (2008)
- Winzeler, E.¹ Gray, N.S.² Han, D.³ Cheng, D.⁴

33
- 77954213899
- Chem. Abstr. 2008, 149, 246557.
- (2008) Chem. Abstr. , vol.149 , pp. 246557

34
- 20144366000
- G. Chen, S. Zheng, X. Luo, J. Shen, W. Zhu, H. Liu, C. Gui, J. Zhang, M. Zheng, C.M. Puah, K. Chen, and H. Jiang J. Comb. Chem. 7 2005 398
- (2005) J. Comb. Chem. , vol.7 , pp. 398
- Chen, G.¹ Zheng, S.² Luo, X.³ Shen, J.⁴ Zhu, W.⁵ Liu, H.⁶ Gui, C.⁷ Zhang, J.⁸ Zheng, M.⁹ Puah, C.M.¹⁰ Chen, K.¹¹ Jiang, H.¹²

35
- 33644869311
- F. Carraro, A. Naldini, A. Pucci, G.A. Locatelli, G. Maga, S. Schenone, O. Bruno, A. Ranise, F. Bondavalli, C. Brullo, P. Fossa, G. Menozzi, L. Mosti, M. Modugno, C. Tintori, F. Manetti, and M. Botta J. Med. Chem. 49 2006 1549
- (2006) J. Med. Chem. , vol.49 , pp. 1549
- Carraro, F.¹ Naldini, A.² Pucci, A.³ Locatelli, G.A.⁴ Maga, G.⁵ Schenone, S.⁶ Bruno, O.⁷ Ranise, A.⁸ Bondavalli, F.⁹ Brullo, C.¹⁰ Fossa, P.¹¹ Menozzi, G.¹² Mosti, L.¹³ Modugno, M.¹⁴ Tintori, C.¹⁵ Manetti, F.¹⁶ Botta, M.¹⁷

36
- 0033200390
- Y. Liu, A. Bishop, L. Witucki, B. Kraybill, E. Shimizu, J. Tsien, J. Ubersax, J. Blethrow, D.O. Morgan, and K.M. Shokat Chem. Biol. 6 1999 671
- (1999) Chem. Biol. , vol.6 , pp. 671
- Liu, Y.¹ Bishop, A.² Witucki, L.³ Kraybill, B.⁴ Shimizu, E.⁵ Tsien, J.⁶ Ubersax, J.⁷ Blethrow, J.⁸ Morgan, D.O.⁹ Shokat, K.M.¹⁰

37
- 33750076068
- R.H. Alvarez, H.M. Kantarjian, and J.E. Cortes Cancer 107 2006 1918
- (2006) Cancer , vol.107 , pp. 1918
- Alvarez, R.H.¹ Kantarjian, H.M.² Cortes, J.E.³

38
- 9144274081
- J.M. Stevenson, and P.D. Mulready J. Am. Chem. Soc. 125 2003 1437
- (2003) J. Am. Chem. Soc. , vol.125 , pp. 1437
- Stevenson, J.M.¹ Mulready, P.D.²

39
- 77954214851
- http://accelrys.com/events/webinars/discovery-studio-25/.

40
- 11644261806
- G.M. Morris, D.S. Goodsell, R.S. Halliday, R. Huey, W.E. Hart, R.K. Belew, and A.J. Olson J. Comput. Chem. 19 1998 1639
- (1998) J. Comput. Chem. , vol.19 , pp. 1639
- Morris, G.M.¹ Goodsell, D.S.² Halliday, R.S.³ Huey, R.⁴ Hart, W.E.⁵ Belew, R.K.⁶ Olson, A.J.⁷

41
- 34047220034
- H. Huang, H. Liu, K. Chen, and H. Jiang J. Comb. Chem. 9 2007 197
- (2007) J. Comb. Chem. , vol.9 , pp. 197
- Huang, H.¹ Liu, H.² Chen, K.³ Jiang, H.⁴

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