메뉴 건너뛰기




Volumn 19, Issue 3, 2009, Pages 167-175

Src activation in melanoma and Src inhibitors as therapeutic agents in melanoma

Author keywords

[No Author keywords available]

Indexed keywords

BOSUTINIB; CISPLATIN; DASATINIB; PACLITAXEL; PHOSPHOTYROSINE; PLATINUM DERIVATIVE; PROTEIN TYROSINE KINASE; TEMOZOLOMIDE; TETRAZOLIUM; ANILINE DERIVATIVE; ANTINEOPLASTIC AGENT; DACARBAZINE; DRUG DERIVATIVE; NITRILE; PROTEIN KINASE INHIBITOR; PYRIMIDINE DERIVATIVE; QUINOLINE DERIVATIVE; THIAZOLE DERIVATIVE;

EID: 67849128649     PISSN: 09608931     EISSN: None     Source Type: Journal    
DOI: 10.1097/CMR.0b013e328304974c     Document Type: Article
Times cited : (51)

References (36)
  • 1
    • 2942618768 scopus 로고    scopus 로고
    • A renaissance for SRC
    • Yeatman TJ. A renaissance for SRC. Nat Rev Cancer 2004; 4:470-480.
    • (2004) Nat Rev Cancer , vol.4 , pp. 470-480
    • Yeatman, T.J.1
  • 2
    • 0029069540 scopus 로고
    • Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein
    • Yu CL, Meyer DJ, Campbell GS. Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. Science 1995; 269:81-83.
    • (1995) Science , vol.269 , pp. 81-83
    • Yu, C.L.1    Meyer, D.J.2    Campbell, G.S.3
  • 3
    • 0035374609 scopus 로고    scopus 로고
    • The hunting of the Src
    • Martin GS. The hunting of the Src. Nat Rev Mol Cell Biol 2001; 2:467-475.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 467-475
    • Martin, G.S.1
  • 4
    • 16444363120 scopus 로고    scopus 로고
    • Iterative microarray and RNA interference-based interrogation of the SRC-induced invasive phenotype
    • Irby RB, Malek RL, Bloom G, et al. Iterative microarray and RNA interference-based interrogation of the SRC-induced invasive phenotype. Cancer Res 2005; 65:1814-1821.
    • (2005) Cancer Res , vol.65 , pp. 1814-1821
    • Irby, R.B.1    Malek, R.L.2    Bloom, G.3
  • 5
    • 18644374835 scopus 로고    scopus 로고
    • Identification of Src transformation fingerprint in human colon cancer
    • Malek RL, Irby RB, Guo QM, et al. Identification of Src transformation fingerprint in human colon cancer. Oncogene 2002; 21:7256-7265.
    • (2002) Oncogene , vol.21 , pp. 7256-7265
    • Malek, R.L.1    Irby, R.B.2    Guo, Q.M.3
  • 6
    • 0037080135 scopus 로고    scopus 로고
    • Activation of Src kinase in primary colorectal carcinoma: An indicator of poor clinical prognosis
    • Aligayer H, Boyd DD, Heiss MM, Abdalla EK, Curley SA, Gallick GE. Activation of Src kinase in primary colorectal carcinoma: an indicator of poor clinical prognosis. Cancer 2002; 94:344-351.
    • (2002) Cancer , vol.94 , pp. 344-351
    • Aligayer, H.1    Boyd, D.D.2    Heiss, M.M.3    Abdalla, E.K.4    Curley, S.A.5    Gallick, G.E.6
  • 7
    • 0032932248 scopus 로고    scopus 로고
    • Activating SRC mutation in a subset of advanced human colon cancers
    • Irby RB, Mao W, Coppola D, et al. Activating SRC mutation in a subset of advanced human colon cancers. Nat Genet 1999; 21:187-190.
    • (1999) Nat Genet , vol.21 , pp. 187-190
    • Irby, R.B.1    Mao, W.2    Coppola, D.3
  • 8
    • 33745243692 scopus 로고    scopus 로고
    • Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival
    • Song L, Morris M, Bagui T, Lee FY, Jove R, Haura EB. Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival. Cancer Res 2006; 66 :5542-5548.
    • (2006) Cancer Res , vol.66 , pp. 5542-5548
    • Song, L.1    Morris, M.2    Bagui, T.3    Lee, F.Y.4    Jove, R.5    Haura, E.B.6
  • 9
    • 33644647192 scopus 로고    scopus 로고
    • Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model
    • Trevino JG, Summy JM, Lesslie DP, et al. Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model. Am J Pathol 2006; 168:962-972.
    • (2006) Am J Pathol , vol.168 , pp. 962-972
    • Trevino, J.G.1    Summy, J.M.2    Lesslie, D.P.3
  • 10
    • 34548701082 scopus 로고    scopus 로고
    • Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/"triple- negative" breast cancer cell lines growing in vitro
    • Finn RS, Dering J, Ginther C, et al. Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/"triple-negative" breast cancer cell lines growing in vitro. Breast Cancer Res Treat 2007.
    • (2007) Breast Cancer Res Treat
    • Finn, R.S.1    Dering, J.2    Ginther, C.3
  • 11
    • 33846870586 scopus 로고    scopus 로고
    • Src as a therapeutic target in anti-hormone/anti-growth factor-resistant breast cancer
    • Hiscox S, Morgan L, Green T, Nicholson RI. Src as a therapeutic target in anti-hormone/anti-growth factor-resistant breast cancer. Endocrine-Relat Cancer 2006; 13 (Suppl 1):S53-S59.
    • (2006) Endocrine-Relat Cancer , vol.13 , Issue.SUPPL. 1
    • Hiscox, S.1    Morgan, L.2    Green, T.3    Nicholson, R.I.4
  • 12
    • 33847728182 scopus 로고    scopus 로고
    • A Src/Abl kinase inhibitor, SKI-606, blocks breast cancer invasion, growth, and metastasis in vitro and in vivo
    • Jallal H, Valentino ML, Chen G, Boschelli F, Ali S, Rabbani SA. A Src/Abl kinase inhibitor, SKI-606, blocks breast cancer invasion, growth, and metastasis in vitro and in vivo. Cancer Res 2007; 67:1580-1588.
    • (2007) Cancer Res , vol.67 , pp. 1580-1588
    • Jallal, H.1    Valentino, M.L.2    Chen, G.3    Boschelli, F.4    Ali, S.5    Rabbani, S.A.6
  • 13
    • 33645464650 scopus 로고    scopus 로고
    • Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein
    • Kotha A, Sekharam M, Cilenti L, et al. Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein. Mol Cancer Ther 2006; 5:621-629.
    • (2006) Mol Cancer Ther , vol.5 , pp. 621-629
    • Kotha, A.1    Sekharam, M.2    Cilenti, L.3
  • 14
    • 27144547509 scopus 로고    scopus 로고
    • Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells
    • Nam S, Kim D, Cheng JQ, et al. Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells. Cancer Res 2005; 65:9185-9189.
    • (2005) Cancer Res , vol.65 , pp. 9185-9189
    • Nam, S.1    Kim, D.2    Cheng, J.Q.3
  • 15
    • 33846261886 scopus 로고    scopus 로고
    • The Src signaling pathway: A potential target in melanoma and other malignancies
    • Homsi J, Cubitt C, Daud A. The Src signaling pathway: a potential target in melanoma and other malignancies. Expert Opin Ther Targets 2007; 11: 91-100.
    • (2007) Expert Opin Ther Targets , vol.11 , pp. 91-100
    • Homsi, J.1    Cubitt, C.2    Daud, A.3
  • 16
    • 31144459985 scopus 로고    scopus 로고
    • Oncogenic pathway signatures in human cancers as a guide to targeted therapies
    • Bild AH, Yao G, Chang JT, et al. Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature 2006; 439:353-357.
    • (2006) Nature , vol.439 , pp. 353-357
    • Bild, A.H.1    Yao, G.2    Chang, J.T.3
  • 17
    • 33845806858 scopus 로고    scopus 로고
    • In vitro and in vivo activity of SKI-606, a novel Src-Abl inhibitor, against imatinib-resistant Bcr-Abl + neoplastic cells
    • Puttini M, Coluccia AM, Boschelli F, et al. In vitro and in vivo activity of SKI-606, a novel Src-Abl inhibitor, against imatinib-resistant Bcr-Abl + neoplastic cells. Cancer Res 2006; 66:11314-11322.
    • (2006) Cancer Res , vol.66 , pp. 11314-11322
    • Puttini, M.1    Coluccia, A.M.2    Boschelli, F.3
  • 18
    • 33644532202 scopus 로고    scopus 로고
    • SKI-606 decreases growth and motility of colorectal cancer cells by preventing pp60(c-Src)-dependent tyrosine phosphorylation of beta-catenin and its nuclear signaling
    • Coluccia AM, Benati D, Dekhil H, De Filippo A, Lan C, Gambacorti-Passerini C. SKI-606 decreases growth and motility of colorectal cancer cells by preventing pp60(c-Src)-dependent tyrosine phosphorylation of beta-catenin and its nuclear signaling. Cancer Res 2006; 66:2279-2286.
    • (2006) Cancer Res , vol.66 , pp. 2279-2286
    • Coluccia, A.M.1    Benati, D.2    Dekhil, H.3    De Filippo, A.4    Lan, C.5    Gambacorti-Passerini, C.6
  • 20
    • 33745063122 scopus 로고    scopus 로고
    • SRC inhibitors as potential therapeutic agents for human cancers
    • Trevino JG, Summy JM, Gallick GE. SRC inhibitors as potential therapeutic agents for human cancers. Mini Rev Med Chem 2006; 6:681-687.
    • (2006) Mini Rev Med Chem , vol.6 , pp. 681-687
    • Trevino, J.G.1    Summy, J.M.2    Gallick, G.E.3
  • 21
    • 18644380911 scopus 로고    scopus 로고
    • Roles of activated Src and Stat3 signaling in melanoma tumor cell growth
    • Niu G, Bowman T, Huang M, et al. Roles of activated Src and Stat3 signaling in melanoma tumor cell growth. Oncogene 2002; 21:7001-7010.
    • (2002) Oncogene , vol.21 , pp. 7001-7010
    • Niu, G.1    Bowman, T.2    Huang, M.3
  • 22
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
    • Chou TC, Talalay P. Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul 1984; 22:27-55.
    • (1984) Adv Enzyme Regul , vol.22 , pp. 27-55
    • Chou, T.C.1    Talalay, P.2
  • 24
    • 0034693877 scopus 로고    scopus 로고
    • Role of Src expression and activation in human cancer
    • Irby RB, Yeatman TJ. Role of Src expression and activation in human cancer. Oncogene 2000; 19:5636-5642.
    • (2000) Oncogene , vol.19 , pp. 5636-5642
    • Irby, R.B.1    Yeatman, T.J.2
  • 25
    • 33644864094 scopus 로고    scopus 로고
    • Involvement of Src family kinases in N-cadherin phosphorylation and beta-catenin dissociation during transendothelial migration of melanoma cells
    • Qi J, Wang J, Romanyuk O, Siu CH. Involvement of Src family kinases in N-cadherin phosphorylation and beta-catenin dissociation during transendothelial migration of melanoma cells. Mol Biol Cell 2006; 17: 1261-1272.
    • (2006) Mol Biol Cell , vol.17 , pp. 1261-1272
    • Qi, J.1    Wang, J.2    Romanyuk, O.3    Siu, C.H.4
  • 26
    • 33748802513 scopus 로고    scopus 로고
    • STAT5 phosphorylation in malignant melanoma is important for survival and is mediated through SRC and JAK1 kinases
    • Mirmohammadsadegh A, Hassan M, Bardenheuer W, et al. STAT5 phosphorylation in malignant melanoma is important for survival and is mediated through SRC and JAK1 kinases. J Invest Dermatol 2006; 126:2272-2280.
    • (2006) J Invest Dermatol , vol.126 , pp. 2272-2280
    • Mirmohammadsadegh, A.1    Hassan, M.2    Bardenheuer, W.3
  • 27
    • 13544252467 scopus 로고    scopus 로고
    • Tumor metastasis but not tumor growth is dependent on Src-mediated vascular permeability
    • Criscuoli ML, Nguyen M, Eliceiri BP. Tumor metastasis but not tumor growth is dependent on Src-mediated vascular permeability. Blood 2005; 105:1508-1514.
    • (2005) Blood , vol.105 , pp. 1508-1514
    • Criscuoli, M.L.1    Nguyen, M.2    Eliceiri, B.P.3
  • 28
    • 33745253734 scopus 로고    scopus 로고
    • Alpha-V-dependent outside-in signaling is required for the regulation of CD44 surface expression, MMP-2 secretion, and cell migration by osteopontin in human melanoma cells
    • Samanna V, Wei H, Ego-Osuala D, Chellaiah MA. Alpha-V-dependent outside-in signaling is required for the regulation of CD44 surface expression, MMP-2 secretion, and cell migration by osteopontin in human melanoma cells. Exp Cell Res 2006; 312:2214-2230.
    • (2006) Exp Cell Res , vol.312 , pp. 2214-2230
    • Samanna, V.1    Wei, H.2    Ego-Osuala, D.3    Chellaiah, M.A.4
  • 29
    • 0344394308 scopus 로고    scopus 로고
    • The laminin receptor modulates granulocyte-macrophage colony-stimulating factor receptor complex formation and modulates its signaling
    • Chen J, Carcamo JM, Borquez-Ojeda O, Erdjument-Bromage H, Tempst P, Golde DW. The laminin receptor modulates granulocyte-macrophage colony-stimulating factor receptor complex formation and modulates its signaling. Proc Natl Acad Sci U S A 2003; 100:14000-14005.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 14000-14005
    • Chen, J.1    Carcamo, J.M.2    Borquez-Ojeda, O.3    Erdjument-Bromage, H.4    Tempst, P.5    Golde, D.W.6
  • 30
    • 0141921990 scopus 로고    scopus 로고
    • Release of vascular endothelial growth factor from a human melanoma cell line, WM35, is induced by hypoxia but not ultraviolet radiation and is potentiated by activated Ras mutation
    • Shellman YG, Park YL, Marr DG, et al. Release of vascular endothelial growth factor from a human melanoma cell line, WM35, is induced by hypoxia but not ultraviolet radiation and is potentiated by activated Ras mutation. J Invest Dermatol 2003; 121:910-917.
    • (2003) J Invest Dermatol , vol.121 , pp. 910-917
    • Shellman, Y.G.1    Park, Y.L.2    Marr, D.G.3
  • 31
    • 0035870249 scopus 로고    scopus 로고
    • Overexpression of a dominant-negative signal transducer and activator of transcription 3 variant in tumor cells leads to production of soluble factors that induce apoptosis and cell cycle arrest
    • Niu G, Shain KH, Huang M, et al. Overexpression of a dominant-negative signal transducer and activator of transcription 3 variant in tumor cells leads to production of soluble factors that induce apoptosis and cell cycle arrest. Cancer Res 2001; 61:3276-3280.
    • (2001) Cancer Res , vol.61 , pp. 3276-3280
    • Niu, G.1    Shain, K.H.2    Huang, M.3
  • 32
    • 21544473172 scopus 로고    scopus 로고
    • Targeting STAT3 affects melanoma on multiple fronts
    • Kortylewski M, Jove R, Yu H. Targeting STAT3 affects melanoma on multiple fronts. Cancer metastasis Rev 2005; 24:315-327.
    • (2005) Cancer Metastasis Rev , vol.24 , pp. 315-327
    • Kortylewski, M.1    Jove, R.2    Yu, H.3
  • 33
    • 20444500171 scopus 로고    scopus 로고
    • SKI-606, a Src/Abl inhibitor with in vivo activity in colon tumor xenograft models
    • Golas JM, Lucas J, Etienne C, et al. SKI-606, a Src/Abl inhibitor with in vivo activity in colon tumor xenograft models. Cancer Res 2005; 65:5358-5364.
    • (2005) Cancer Res , vol.65 , pp. 5358-5364
    • Golas, J.M.1    Lucas, J.2    Etienne, C.3
  • 34
    • 33947512381 scopus 로고    scopus 로고
    • An integrated genomic-based approach to individualized treatment of patients with advanced-stage ovarian cancer
    • Dressman HK, Berchuck A, Chan G, et al. An integrated genomic-based approach to individualized treatment of patients with advanced-stage ovarian cancer. J Clin Oncol 2007; 25:517-525.
    • (2007) J Clin Oncol , vol.25 , pp. 517-525
    • Dressman, H.K.1    Berchuck, A.2    Chan, G.3
  • 35
    • 33947225176 scopus 로고    scopus 로고
    • Identification of candidate molecular markers predicting sensitivity in solid tumors to dasatinib: Rationale for patient selection
    • DOI 10.1158/0008-5472.CAN-06-3633
    • Huang F, Reeves K, Han X, et al. Identification of candidate molecular markers predicting sensitivity in solid tumors to dasatinib: rationale for patient selection. Cancer Res 2007; 67:2226-2238. (Pubitemid 46424242)
    • (2007) Cancer Research , vol.67 , Issue.5 , pp. 2226-2238
    • Huang, F.1    Reeves, K.2    Han, X.3    Fairchild, C.4    Platero, S.5    Wong, T.W.6    Lee, F.7    Shaw, P.8    Clark, E.9
  • 36
    • 34047265691 scopus 로고    scopus 로고
    • Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on SRC kinase for survival
    • Shor AC, Keschman EA, Lee FY, et al. Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on SRC kinase for survival. Cancer Res 2007; 67 :2800-2808.
    • (2007) Cancer Res , vol.67 , pp. 2800-2808
    • Shor, A.C.1    Keschman, E.A.2    Lee, F.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.