Minimal effect of CD103 expression on the control of a chronic antiviral immune response

Viral Immunology

Volumn 23, Issue 3, 2010, Pages 285-294

  Fousteri, Georgia ^a   Dave, Amy ^a   Juntti, Therese ^a   Morin, Bret ^a   McClure, Malina ^a   Von Herrath, Matthias ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA E INTEGRIN; ALPHA INTEGRIN; CD103 ANTIGEN; CYTOKINE; PROGRAMMED DEATH 1 RECEPTOR; UNCLASSIFIED DRUG; ALPHA E INTEGRINS; LEUKOCYTE ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTIVIRAL ACTIVITY; ARTICLE; CD4 LYMPHOCYTE COUNT; CD4+ CD25+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL HOMING; CELL POPULATION; CELL SPECIFICITY; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; EPITHELIUM; FEMALE; IMMUNE RESPONSE; INTESTINE; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MALE; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; T LYMPHOCYTE; VIRUS LOAD; VIRUS STRAIN; ANIMAL; CD4+ T LYMPHOCYTE; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; MOUSE MUTANT;

LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MUS;

ANIMALS; ANTIGENS, CD; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; IMMUNOLOGIC MEMORY; INTEGRIN ALPHA CHAINS; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, KNOCKOUT;

EID: 77954165806     PISSN: 08828245     EISSN: None     Source Type: Journal    
DOI: 10.1089/vim.2009.0110     Document Type: Article

References (56)

1. Virgin HW, Wherry EJ, and Ahmed R: Redefining chronic viral infection. Cell 2009;138:30-50.
2. Rehermann B, and Nascimbeni M: Immunology of hepatitis B virus and hepatitis C virus infection. Nat Rev Immunol 2005;5:215-229.
3. Kaech SM, and Wherry EJ: Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection. Immunity 2007;27:393-405.
4. Mescher MF, Curtsinger JM, Agarwal P, et al.: Signals required for programming effector and memory development by CD8+ T cells. Immunol Rev 2006;211:81-92.
5. Wherry EJ, Ha SJ, Kaech SM, et al.: Molecular signature of CD8+ T cell exhaustion during chronic viral infection. Immunity 2007;27:670-684.
6. Ha SJ, West EE, Araki K, et al.: Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections. Immunol Rev 2008;223:317-333.
7. Kim WM, and Sigalov AB: Viral pathogenesis, modulation of immune receptor signaling and treatment. Adv Exp Med Biol 2008;640:325-349.
8. Banks TA, Rickert S, and Ware CF: Restoring immune defenses via lymphotoxin signaling: lessons from cytomegalovirus. Immunol Res 2006;34:243-254.
9. von Herrath M, and Whitton JL: Animal models using lymphocytic choriomeningitis virus. Curr Protoc Immunol Chapter 19 2001;Unit 19;10.
10. Suvas S, Kumaraguru U, Pack CD, et al.: CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses. J Exp Med 2003;198:889-901.
11. Ebinuma H, Nakamoto N, Li Y, et al.: Identification and in vitro expansion of functional antigen-specific CD25+FoxP3+ regulatory T cells in hepatitis C virus infection. J Virol 2008; 82:5043-5053.
12. Fernandez MA, Puttur FK, Wang YM, et al.: T regulatory cells contribute to the attenuated primary CD8+ and CD4+ T cell responses to herpes simplex virus type 2 in neonatal mice. J Immunol 2008;180:1556-1564.
13. Serra P, Amrani A, Yamanouchi J, et al.: CD40 ligation releases immature dendritic cells from the control of regulatory CD4+CD25+ T cells. Immunity 2003;19:877-889.
14. Sakaguchi S: Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 2004;22:531-562.
15. Dietz SB, Whitaker-Menezes D, and Lessin SR: The role of alpha E beta 7 integrin (CD103) and E-cadherin in epidermotropism in cutaneous T-cell lymphoma. J Cutan Pathol 1996;23:312-318.
16. Agace WW, Higgins JM, Sadasivan B, et al.: T-lymphocyteepithelial- cell interactions: integrin alpha(E)(CD103)beta(7), LEEP-CAM and chemokines. Curr Opin Cell Biol 2000;12: 563-568.
17. Suffia I, Reckling SK, Salay G, and Belkaid Y: A role for CD103 in the retention of CD4+CD25+ Treg and control of Leishmania major infection. J Immunol 2005;174:5444-5455.
18. Brown DW, Furness J, Speight PM, et al.: Mechanisms of binding of cutaneous lymphocyte-associated antigen-positive and alphaebeta7-positive lymphocytes to oral and skin keratinocytes. Immunology 1999;98:9-15.
19. Strauch UG, Mueller RC, Li XY, et al.: Integrin alpha E(CD103)beta 7 mediates adhesion to intestinal microvascular endothelial cell lines via an Ecadherin-independent interaction. J Immunol 2001;166:3506-3514.
20. Feng Y, Wang D, Yuan R, et al.: CD103 expression is required for destruction of pancreatic islet allografts by CD8(+) T cells. J Exp Med 2002;196:877-886.
21. Oldstone MB: Anatomy of viral persistence. PLoS Pathog 2009;5:e1000523.
22. Zinkernagel RM: Lymphocytic choriomeningitis virus and immunology. Curr Top Microbiol Immunol 2002;263: 1-5.
23. Gallimore A, Hengartner H, and Zinkernagel R: Hierarchies of antigen-specific cytotoxic T-cell responses. Immunol Rev 1998;164:29-36.
24. Marker O, and Volkert M: Studies on cell-mediated immunity to lymphocytic choriomeningitis virus in mice. J Exp Med 1973;137:1511-1525.
25. Salvato M, Borrow P, Shimomaye E, and Oldstone MB: Molecular basis of viral persistence: a single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with suppression of the antiviral cytotoxic T-lymphocyte response and establishment of persistence. J Virol 1991;65:1863-1869.
26. Ahmed R, Hahn CS, Somasundaram T, et al.: Molecular basis of organ-specific selection of viral variants during chronic infection. J Virol 1991;65:4242-4247.
27. Matloubian M, Somasundaram T, Kolhekar SR, et al.: Genetic basis of viral persistence: single amino acid change in the viral glycoprotein affects ability of lymphocytic choriomeningitis virus to persist in adult mice. J Exp Med 1990; 172:1043-1048.
28. Moskophidis D, Lechner F, Pircher H, and Zinkernagel RM: Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells. Nature 1993;362:758-761.
29. Zajac AJ, Blattman JN, Murali-Krishna K, et al.: Viral immune evasion due to persistence of activated T cells without effector function. J Exp Med 1998;188:2205-2213.
30. Shin H, and Wherry EJ: CD8 T cell dysfunction during chronic viral infection. Curr Opin Immunol 2007;19:408-415.
31. Ejrnaes M, Filippi CM, Martinic MM, et al.: Resolution of a chronic viral infection after interleukin-10 receptor blockade. J Exp Med 2006;203:2461-2472.
32. Brooks DG, Trifilo MJ, Edelmann KH, et al.: Interleukin-10 determines viral clearance or persistence in vivo. Nat Med 2006;12:1301-1309.
33. Elsaesser H, Sauer K, and Brooks DG: IL-21 is required to control chronic viral infection. Science 2009;324:1569-1572.
34. Frohlich A, Kisielow J, Schmitz I, et al.: IL-21R on T cells is critical for sustained functionality and control of chronic viral infection. Science 2009;324:1576-1580.
35. Yi JS, Du M, and Zajac AJ: A vital role for interleukin-21 in the control of a chronic viral infection. Science 2009;324: 1572-1576.
36. Fousteri G, Dave A, Juntti T, and von Herrath M: CD103 is dispensable for antiviral immunity and autoimmunity in a mouse model of virally-induced autoimmune diabetes. J Autoimmun 2009;32:70-77.
37. Schon MP, Arya A, Murphy EA, et al.: Mucosal T lymphocyte numbers are selectively reduced in integrin alpha E (CD103)-deficient mice. J Immunol 1999;162:6641-6649.
38. Filippi CM, Estes EA, Oldham JE, and von Herrath MG: Immunoregulatory mechanisms triggered by viral infections protect from type 1 diabetes in mice. J Clin Invest 2009;119: 1515-1523.
39. Barber DL, Wherry EJ, Masopust D, et al.: Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 2006;439:682-687.
40. Freeman GJ, Long AJ, Iwai Y, et al.: Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med 2000;192:1027-1034.
41. Ishida Y, Agata Y, Shibahara K, and Honjo T: Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO J 1992;11:3887-3895.
42. Andrew DP, Rott LS, Kilshaw PJ, and Butcher EC: Distribution of alpha 4 beta 7 and alpha E beta 7 integrins on thymocytes, intestinal epithelial lymphocytes and peripheral lymphocytes. Eur J Immunol 1996;26:897-905.
43. Shacklett BL, Cox CA, Sandberg JK, et al.: Trafficking of human immunodeficiency virus type 1-specific CD8+ T cells to gut-associated lymphoid tissue during chronic infection. J Virol 2003;77:5621-5631.
44. Blackburn SD, Shin H, Freeman GJ, and Wherry EJ: Selective expansion of a subset of exhausted CD8 T cells by alphaPD-L1 blockade. Proc Natl Acad Sci USA 2008;105: 15016-15021.
45. Blackburn SD, Shin H, Haining WN, et al.: Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection. Nat Immunol 2009;10: 29-37.
46. Alatrakchi N, Graham CS, van der Vliet HJ, et al.: Hepatitis C virus (HCV) specific CD8+ cells produce transforming growth factor beta that can suppress HCV-specific T-cell responses. J Virol 2007;81:5882-5892.
47. Homann D, Dummer W, Wolfe T, et al.: Lack of intrinsic CTLA-4 expression has minimal effect on regulation of antiviral T-cell immunity. J Virol 2006;80:270-280.
48. Richter K, Agnellini P, and Oxenius A: On the role of the inhibitory receptor LAG-3 in acute and chronic LCMV infection. Int Immunol. 2009;22:13-23.
49. Mueller SN, Matloubian M, Clemens DM, et al.: Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection. Proc Natl Acad Sci USA 2007;104:15430-15435.
50. Sevilla N, McGavern DB, Teng C, et al.: Viral targeting of hematopoietic progenitors and inhibition of DC maturation as a dual strategy for immune subversion. J Clin Invest 2004;113:737-745.
51. Cepek KL, Parker CM, Madara JL, and Brenner MB: Integrin alpha E beta 7 mediates adhesion of T lymphocytes to epithelial cells. J Immunol 1993;150:3459-3470.
52. Kilshaw PJ: Expression of the mucosal T cell integrin alpha M290 beta 7 by a major subpopulation of dendritic cells in mice. Eur J Immunol 1993;23:3365-3368.
53. Robinson PW, Green SJ, Carter C, et al.: Studies on transcriptional regulation of the mucosal T-cell integrin alphaEbeta7 (CD103). Immunology 2001;103:146-154.
54. Coombes JL, Siddiqui KR, Arancibia-Carcamo CV, et al.: Afunctionally specialized population ofmucosal CD103+DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J Exp Med 2007;204:1757-1764.
55. Jaensson E, Uronen-Hansson H, Pabst O, et al.: Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans. J Exp Med 2008;205:2139-2149.
56. Lund JM, Hsing L, Pham TT, and Rudensky AY: Coordination of early protective immunity to viral infection by regulatory T cells. Science 2008;320:1220-1224.