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Volumn 34, Issue 3, 2006, Pages 243-253

Restoring immune defenses via lymphotoxin signaling: Lessons from cytomegalovirus

Author keywords

Antibody immunotherapy; Cytomegalovirus; Herpesvirus; Interferons; Lymphotoxin beta receptor

Indexed keywords

ADALIMUMAB; ANTIVIRUS AGENT; CIDOFOVIR; CYTOKINE; ETANERCEPT; FOMIVIRSEN; FOSCARNET; GANCICLOVIR; INFLIXIMAB; INTERFERON; INTERLEUKIN 2; LENERCEPT; LYMPHOTOXIN; LYMPHOTOXIN BETA RECEPTOR; LYMPHOTOXIN BETA RECEPTOR ANTIBODY; NEUTRALIZING ANTIBODY; PALIVIZUMAB; RECOMBINANT CYTOKINE; RECOMBINANT INTERLEUKIN 2; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VALGANCICLOVIR;

EID: 33746891509     PISSN: 0257277X     EISSN: None     Source Type: Journal    
DOI: 10.1385/IR:34:3:243     Document Type: Review
Times cited : (11)

References (47)
  • 1
    • 0035936797 scopus 로고    scopus 로고
    • The TNF and TNF receptor superfamilies: Integrating mammalian biology
    • Locksley RM, Killeen N and Lenardo MJ: The TNF and TNF receptor superfamilies: Integrating mammalian biology. Cell 2001; 104:487-501.
    • (2001) Cell , vol.104 , pp. 487-501
    • Locksley, R.M.1    Killeen, N.2    Lenardo, M.J.3
  • 3
    • 0028277665 scopus 로고
    • Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin
    • De Togni P, Goellner J, Ruddle NH, et al: Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin. Science 1994; 264:703-706.
    • (1994) Science , vol.264 , pp. 703-706
    • De Togni, P.1    Goellner, J.2    Ruddle, N.H.3
  • 4
    • 17644400505 scopus 로고    scopus 로고
    • Network communications: Lymphotoxins, LIGHT, and TNF
    • Ware CF: Network communications: lymphotoxins, LIGHT, and TNF. Annu Rev Immunol 2005; 23:787-819.
    • (2005) Annu Rev Immunol , vol.23 , pp. 787-819
    • Ware, C.F.1
  • 5
    • 0031907988 scopus 로고    scopus 로고
    • LIGHT, a new member of the TNF superfamily and lymphotoxin a are ligands for herpesvirus entry mediator
    • Mauri DN, Ebner R, Montgomery RI, et al: LIGHT, a new member of the TNF superfamily and lymphotoxin a are ligands for herpesvirus entry mediator. Immunity 1998; 8:21-30.
    • (1998) Immunity , vol.8 , pp. 21-30
    • Mauri, D.N.1    Ebner, R.2    Montgomery, R.I.3
  • 6
    • 19944433635 scopus 로고    scopus 로고
    • B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator
    • Sedy JR, Gavrieli M, Potter KG, et al: B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator. Nat Immunol 2005; 6:90-98.
    • (2005) Nat Immunol , vol.6 , pp. 90-98
    • Sedy, J.R.1    Gavrieli, M.2    Potter, K.G.3
  • 7
    • 24944486256 scopus 로고    scopus 로고
    • Evolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathway
    • USA
    • Cheung TC, Humphreys IR, Potter KG, et al: Evolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathway. Proc Natl Acad Sci USA 2005; 102:13218-13223.
    • (2005) Proc Natl Acad Sci , vol.102 , pp. 13218-13223
    • Cheung, T.C.1    Humphreys, I.R.2    Potter, K.G.3
  • 8
    • 0034691531 scopus 로고    scopus 로고
    • A chemokine-driven positive feedback loop organizes lymphoid follicles
    • Ansel KM, Ngo VN, Hyman PL, et al: A chemokine-driven positive feedback loop organizes lymphoid follicles. Nature 2000; 406:309-314.
    • (2000) Nature , vol.406 , pp. 309-314
    • Ansel, K.M.1    Ngo, V.N.2    Hyman, P.L.3
  • 9
    • 0036644712 scopus 로고    scopus 로고
    • Differing activities of homeostatic chemokines CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesis
    • Luther SA, Bidgol A, Hargreaves DC, et al: Differing activities of homeostatic chemokines CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesis. J Immunol 2002; 169:424-433.
    • (2002) J Immunol , vol.169 , pp. 424-433
    • Luther, S.A.1    Bidgol, A.2    Hargreaves, D.C.3
  • 10
    • 0031847335 scopus 로고    scopus 로고
    • Expression of the lymphotoxin β-receptor on follicular stromal cells in human lymphoid tissue
    • Murphy M, Walter BN, Pike-Nobile L, et al: Expression of the lymphotoxin β-receptor on follicular stromal cells in human lymphoid tissue. Cell Death Differentiation 1998; 5:497-505.
    • (1998) Cell Death Differentiation , vol.5 , pp. 497-505
    • Murphy, M.1    Walter, B.N.2    Pike-Nobile, L.3
  • 11
    • 1842507448 scopus 로고    scopus 로고
    • Blocking lymphotoxin-beta receptor activation diminishes inflammation via reduced mucosal addressin cell adhesion molecule-1 (MAdCAM-1) expression and leucocyte margination in chronic DSS-induced colitis
    • Stopfer P, Obermeier F, Dunger N, et al: Blocking lymphotoxin-beta receptor activation diminishes inflammation via reduced mucosal addressin cell adhesion molecule-1 (MAdCAM-1) expression and leucocyte margination in chronic DSS-induced colitis. Clin Exp Immunol 2004; 136:21-29.
    • (2004) Clin Exp Immunol , vol.136 , pp. 21-29
    • Stopfer, P.1    Obermeier, F.2    Dunger, N.3
  • 12
    • 2942755965 scopus 로고    scopus 로고
    • LIGHT expression by mucosal T cells may regulate IFN-gamma expression in the intestine
    • Cohavy O, Zhou J, Granger SW, Ware CF, Targan SR: LIGHT expression by mucosal T cells may regulate IFN-gamma expression in the intestine. J Immunol 2004;173:251-258.
    • (2004) J Immunol , vol.173 , pp. 251-258
    • Cohavy, O.1    Zhou, J.2    Granger, S.W.3    Ware, C.F.4    Targan, S.R.5
  • 13
    • 0034667773 scopus 로고    scopus 로고
    • Reciprocal expression of the TNF family receptor herpes virus entry mediator and its ligand LIGHT on activated T cells: LIGHT down-regulates its own receptor
    • Morel Y, Schiano de Colella JM, Harrop J, et al: Reciprocal expression of the TNF family receptor herpes virus entry mediator and its ligand LIGHT on activated T cells: LIGHT down-regulates its own receptor. J Immunol 2000; 165:4397-4404.
    • (2000) J Immunol , vol.165 , pp. 4397-4404
    • Morel, Y.1    Schiano De Colella, J.M.2    Harrop, J.3
  • 14
    • 0030984895 scopus 로고    scopus 로고
    • A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation
    • Kwon BS, Tan KB, Ni J, et al: A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation. J Biol Chem 1997; 272:14272-14276.
    • (1997) J Biol Chem , vol.272 , pp. 14272-14276
    • Kwon, B.S.1    Tan, K.B.2    Ni, J.3
  • 15
    • 0035253562 scopus 로고    scopus 로고
    • Signal via lymphotoxin-beta R on bone marrow stromal cells is required for an early checkpoint of NK cell development
    • Wu Q, Sun Y, Wang J, et al: Signal via lymphotoxin-beta R on bone marrow stromal cells is required for an early checkpoint of NK cell development. J Immunol 2001; 166:1684-1689.
    • (2001) J Immunol , vol.166 , pp. 1684-1689
    • Wu, Q.1    Sun, Y.2    Wang, J.3
  • 16
    • 0034661974 scopus 로고    scopus 로고
    • Membrane lymphotoxin is required early in ontogeny for development of different subpopulations of NK T cells
    • Elewaut D, Brossay L, Santee SM, et al: Membrane lymphotoxin is required early in ontogeny for development of different subpopulations of NK T cells. J Immunol 2000; 165:671-679.
    • (2000) J Immunol , vol.165 , pp. 671-679
    • Elewaut, D.1    Brossay, L.2    Santee, S.M.3
  • 17
    • 0032842326 scopus 로고    scopus 로고
    • The requirement of membrane lymphotoxin for the presence of dendritic cells in lymphoid tissue
    • Wu Q, Wang Y, Wang J, Hedgeman EO, Browning JL, Fu Y-X: The requirement of membrane lymphotoxin for the presence of dendritic cells in lymphoid tissue. J Exp Med 1999; 190:629-638.
    • (1999) J Exp Med , vol.190 , pp. 629-638
    • Wu, Q.1    Wang, Y.2    Wang, J.3    Hedgeman, E.O.4    Browning, J.L.5    Fu, Y.-X.6
  • 18
    • 0037441879 scopus 로고    scopus 로고
    • Distinct contributions of TNF and LT cytokines to the development of dendritic cells in vitro and their recruitment in vivo
    • Abe K,Yarovinsky FO,Murakami T, et al: Distinct contributions of TNF and LT cytokines to the development of dendritic cells in vitro and their recruitment in vivo. Blood 2003; 101:1477-1483.
    • (2003) Blood , vol.101 , pp. 1477-1483
    • Abe, K.1    Yarovinsky, F.O.2    Murakami, T.3
  • 19
    • 18644380147 scopus 로고    scopus 로고
    • The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways
    • Dejardin E, Droin NM, Delhase M, et al: The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways. Immunity 2002; 17:525-535.
    • (2002) Immunity , vol.17 , pp. 525-535
    • Dejardin, E.1    Droin, N.M.2    Delhase, M.3
  • 20
    • 23244437984 scopus 로고    scopus 로고
    • Contribution of the lymphotoxin beta receptor to liver regeneration
    • Anders RA, Subudhi SK, Wang J, Pfeffer K, Fu YX: Contribution of the lymphotoxin beta receptor to liver regeneration. J Immunol 2005; 175:1295-1300.
    • (2005) J Immunol , vol.175 , pp. 1295-1300
    • Anders, R.A.1    Subudhi, S.K.2    Wang, J.3    Pfeffer, K.4    Fu, Y.X.5
  • 21
    • 0037290767 scopus 로고    scopus 로고
    • Death and survival: Viral regulation of TNF signaling pathways
    • Benedict CA, Banks TA, Ware CF: Death and survival: viral regulation of TNF signaling pathways. Curr Opin Immunol 2003; 15:59-65.
    • (2003) Curr Opin Immunol , vol.15 , pp. 59-65
    • Benedict, C.A.1    Banks, T.A.2    Ware, C.F.3
  • 22
    • 27744592020 scopus 로고    scopus 로고
    • Role of lymphotoxin in experimental models of infectious diseases: Potential benefits and risks of a therapeutic inhibition of the lymphotoxin-beta receptor pathway
    • Spahn TW, Eugster HP, Fontana A, Domschke W, Kucharzik T: Role of lymphotoxin in experimental models of infectious diseases: potential benefits and risks of a therapeutic inhibition of the lymphotoxin-beta receptor pathway. Infect Immun 2005; 73:7077-7088.
    • (2005) Infect Immun , vol.73 , pp. 7077-7088
    • Spahn, T.W.1    Eugster, H.P.2    Fontana, A.3    Domschke, W.4    Kucharzik, T.5
  • 23
    • 0034749494 scopus 로고    scopus 로고
    • Lymphotoxins and cytomegalovirus cooperatively induce interferon-β, establishing host-virus détente
    • Benedict CA, Banks TA, Senderowicz L, et al: Lymphotoxins and cytomegalovirus cooperatively induce interferon-β, establishing host-virus détente. Immunity 2001; 15:617-626.
    • (2001) Immunity , vol.15 , pp. 617-626
    • Benedict, C.A.1    Banks, T.A.2    Senderowicz, L.3
  • 24
    • 21044440573 scopus 로고    scopus 로고
    • A lymphotoxin-IFN-beta axis essential for lymphocyte survival revealed during cytomegalovirus infection
    • Banks TA, Rickert S, Benedict CA, et al: A lymphotoxin-IFN-beta axis essential for lymphocyte survival revealed during cytomegalovirus infection. J Immunol 2005; 174:7217-7225.
    • (2005) J Immunol , vol.174 , pp. 7217-7225
    • Banks, T.A.1    Rickert, S.2    Benedict, C.A.3
  • 25
    • 0030612146 scopus 로고    scopus 로고
    • The lymphotoxin-α (LTα) subunit is essential for the assembly, but not receptor specificity, of the membrane-anchored LTα1β2 heterotrimeric ligand
    • Williams-Abbott L, Walter BN, Cheung T, Goh CR, Porter AG, Ware CF: The lymphotoxin-α (LTα) subunit is essential for the assembly, but not receptor specificity, of the membrane-anchored LTα1β2 heterotrimeric ligand. J Biol Chem 1997; 272: 19451-19456.
    • (1997) J Biol Chem , vol.272 , pp. 19451-19456
    • Williams-Abbott, L.1    Walter, B.N.2    Cheung, T.3    Goh, C.R.4    Porter, A.G.5    Ware, C.F.6
  • 26
    • 0034640539 scopus 로고    scopus 로고
    • The lymphotoxin-beta receptor is necessary and sufficient for LIGHT-mediated apoptosis of tumor cells
    • Rooney IA, Butrovich KD, Glass AA, et al: The lymphotoxin-beta receptor is necessary and sufficient for LIGHT-mediated apoptosis of tumor cells. J Biol Chem 2000; 275:14307-14315.
    • (2000) J Biol Chem , vol.275 , pp. 14307-14315
    • Rooney, I.A.1    Butrovich, K.D.2    Glass, A.A.3
  • 27
    • 33644648365 scopus 로고    scopus 로고
    • Cytomegalovirus infection in solid organ transplant recipients: New challenges and their implications for preventive strategies
    • Singh N: Cytomegalovirus infection in solid organ transplant recipients: new challenges and their implications for preventive strategies. J Clin Virol 2006; 35:474-477.
    • (2006) J Clin Virol , vol.35 , pp. 474-477
    • Singh, N.1
  • 28
    • 0035428084 scopus 로고    scopus 로고
    • Cytomegalovirus infection in immunocompetent and immunocompromised individuals - A review
    • Vancikova Z, Dvorak P: Cytomegalovirus infection in immunocompetent and immunocompromised individuals - a review. Curr Drug Targets Immune Endocr Metabol Disord 2001; 1:179-187.
    • (2001) Curr Drug Targets Immune Endocr Metabol Disord , vol.1 , pp. 179-187
    • Vancikova, Z.1    Dvorak, P.2
  • 29
    • 27244453285 scopus 로고    scopus 로고
    • Human cytomegalovirus, endothelial function and atherosclerosis
    • Grahame-Clarke C: Human cytomegalovirus, endothelial function and atherosclerosis. Herpes 2005; 12:42-45.
    • (2005) Herpes , vol.12 , pp. 42-45
    • Grahame-Clarke, C.1
  • 30
    • 1642553664 scopus 로고    scopus 로고
    • Pathogenesis and prenatal diagnosis of human cytomegalovirus infection
    • Revello MG, Gerna G: Pathogenesis and prenatal diagnosis of human cytomegalovirus infection. J Clin Virol 2004; 29:71-83.
    • (2004) J Clin Virol , vol.29 , pp. 71-83
    • Revello, M.G.1    Gerna, G.2
  • 31
    • 14744270979 scopus 로고    scopus 로고
    • Human cytomegalovirus resistance to antiviral drugs
    • Gilbert C, Boivin G: Human cytomegalovirus resistance to antiviral drugs. Antimicrob Agents Chemother 2005; 49:873-883.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 873-883
    • Gilbert, C.1    Boivin, G.2
  • 32
    • 2542418810 scopus 로고    scopus 로고
    • Clinical and biologic aspects of human cytomegalovirus resistance to antiviral drugs
    • Baldanti F, Lurain N, Gerna G: Clinical and biologic aspects of human cytomegalovirus resistance to antiviral drugs. Hum Immunol 2004; 65:403-409.
    • (2004) Hum Immunol , vol.65 , pp. 403-409
    • Baldanti, F.1    Lurain, N.2    Gerna, G.3
  • 33
    • 0029821897 scopus 로고    scopus 로고
    • Inhibition of human cytomegalovirus immediate-early gene expression by an antisense oligonucleotide complementary to immediate-early RNA
    • Anderson KP, Fox MC, Brown-Driver V, Martin MJ, Azad RF: Inhibition of human cytomegalovirus immediate-early gene expression by an antisense oligonucleotide complementary to immediate-early RNA. AntimicrobAgents Chemother 1996; 40:2004-2011.
    • (1996) AntimicrobAgents Chemother , vol.40 , pp. 2004-2011
    • Anderson, K.P.1    Fox, M.C.2    Brown-Driver, V.3    Martin, M.J.4    Azad, R.F.5
  • 34
    • 22144491548 scopus 로고    scopus 로고
    • Progress toward an elusive goal: Current status of cytomegalovirus vaccines
    • Schleiss MR, Heineman TC: Progress toward an elusive goal: current status of cytomegalovirus vaccines. Expert Rev Vaccines 2005; 4:381-406.
    • (2005) Expert Rev Vaccines , vol.4 , pp. 381-406
    • Schleiss, M.R.1    Heineman, T.C.2
  • 35
    • 0141889231 scopus 로고    scopus 로고
    • Immune reconstitution to cytomegalovirus after allogeneic hematopoietic stem cell transplantation: Impact of host factors, drug therapy, and subclinical reactivation
    • Hakki M, Riddell SR, Storek J, et al: Immune reconstitution to cytomegalovirus after allogeneic hematopoietic stem cell transplantation: impact of host factors, drug therapy, and subclinical reactivation. Blood 2003; 102:3060-3067.
    • (2003) Blood , vol.102 , pp. 3060-3067
    • Hakki, M.1    Riddell, S.R.2    Storek, J.3
  • 36
    • 13244260712 scopus 로고    scopus 로고
    • Cytomegalovirus disease before hematopoietic cell transplantation as a risk for complications after transplantation
    • Fries BC, Riddell SR, Kim HW, et al: Cytomegalovirus disease before hematopoietic cell transplantation as a risk for complications after transplantation. Biol Blood Marrow Transplant 2005; 11:136-148.
    • (2005) Biol Blood Marrow Transplant , vol.11 , pp. 136-148
    • Fries, B.C.1    Riddell, S.R.2    Kim, H.W.3
  • 38
    • 0345098552 scopus 로고    scopus 로고
    • Modulation of death receptor pathways in oncology
    • Barc
    • de Vries EG, Timmer T, Mulder NH, et al: Modulation of death receptor pathways in oncology. Drugs Today (Barc) 2003; 39 Suppl C:95-109.
    • (2003) Drugs Today , vol.39 , Issue.SUPPL. C , pp. 95-109
    • De Vries, E.G.1    Timmer, T.2    Mulder, N.H.3
  • 39
    • 21344456195 scopus 로고    scopus 로고
    • Anemia and erythropoietin treatment in chronic kidney diseases
    • Santoro A, Canova C: Anemia and erythropoietin treatment in chronic kidney diseases. Minerva Urol Nefrol 2005; 57:23-31.
    • (2005) Minerva Urol Nefrol , vol.57 , pp. 23-31
    • Santoro, A.1    Canova, C.2
  • 40
    • 27744493302 scopus 로고    scopus 로고
    • Guidelines of the National Comprehensive Cancer Network on the use of myeloid growth factors with cancer chemotherapy: A review of the evidence
    • Lyman GH: Guidelines of the National Comprehensive Cancer Network on the use of myeloid growth factors with cancer chemotherapy: a review of the evidence. J Natl Compr Canc Netw 2005; 3:557-571.
    • (2005) J Natl Compr Canc Netw , vol.3 , pp. 557-571
    • Lyman, G.H.1
  • 41
    • 0028134983 scopus 로고
    • An anti-IL-2 antibody increases serum half-life and improves antitumor efficacy of human recombinant interleukin-2
    • Courtney LP, Phelps JL, Karavodin LM: An anti-IL-2 antibody increases serum half-life and improves antitumor efficacy of human recombinant interleukin-2. Immunopharmacology 1994; 28:223-232.
    • (1994) Immunopharmacology , vol.28 , pp. 223-232
    • Courtney, L.P.1    Phelps, J.L.2    Karavodin, L.M.3
  • 42
    • 25844489943 scopus 로고    scopus 로고
    • Infection by the respiratory syncytial virus in infants and young children at high risk
    • Bonnet D, Schmaltz AA, Feltes TF: Infection by the respiratory syncytial virus in infants and young children at high risk. Cardiol Young 2005; 15:256-265.
    • (2005) Cardiol Young , vol.15 , pp. 256-265
    • Bonnet, D.1    Schmaltz, A.A.2    Feltes, T.F.3
  • 43
    • 0027361432 scopus 로고
    • Construction and initial characterization of a mouse-human chimeric anti-TNF antibody
    • Knight DM, Trinh H, Le J, et al: Construction and initial characterization of a mouse-human chimeric anti-TNF antibody. Mol Immunol 1993; 30:1443-1453.
    • (1993) Mol Immunol , vol.30 , pp. 1443-1453
    • Knight, D.M.1    Trinh, H.2    Le, J.3
  • 44
    • 0027198002 scopus 로고
    • Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists
    • Mohler KM, Torrance DS, Smith CA, et al: Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists. J Immunol 1993; 151:1548-1561.
    • (1993) J Immunol , vol.151 , pp. 1548-1561
    • Mohler, K.M.1    Torrance, D.S.2    Smith, C.A.3
  • 45
    • 0035933155 scopus 로고    scopus 로고
    • Stimulation via CD40 can substitute for CD4 T cell function in preventing reactivation of a latent herpesvirus
    • USA
    • Sarawar SR, Lee BJ, Reiter SK, Schoenberger SP: Stimulation via CD40 can substitute for CD4 T cell function in preventing reactivation of a latent herpesvirus. Proc Natl Acad Sci USA 2001; 98:6325-6329.
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 6325-6329
    • Sarawar, S.R.1    Lee, B.J.2    Reiter, S.K.3    Schoenberger, S.P.4
  • 46
    • 0030006198 scopus 로고    scopus 로고
    • Signalling through the lymphotoxin-b receptor induces the death of some adenocarcinoma tumor lines
    • Browning JL, Miatkowski K, Sizing I, et al: Signalling through the lymphotoxin-b receptor induces the death of some adenocarcinoma tumor lines. J Exp Med 1996; 183:867-878.
    • (1996) J Exp Med , vol.183 , pp. 867-878
    • Browning, J.L.1    Miatkowski, K.2    Sizing, I.3


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