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Volumn 462, Issue 1-2, 2010, Pages 26-33

Effects of pharmacological agents on the lifespan phenotype of Drosophila DJ-1β mutants

Author keywords

Tocopherol; DJ 1; L DOPA; Melatonin; Oxidative stress; Parkinson's disease; Pergolide; SK F 38393; Vitamin C

Indexed keywords

2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; ALPHA TOCOPHEROL; ANTIOXIDANT; ANTIPARKINSON AGENT; ASCORBIC ACID; BUTYLCRESOL; CATALASE; DJ 1 PROTEIN; DJ 1BETA PROTEIN; LEVODOPA; MELATONIN; PERGOLIDE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

EID: 77954144175     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2010.04.009     Document Type: Article
Times cited : (42)

References (55)
  • 2
  • 3
    • 44449137435 scopus 로고    scopus 로고
    • Antioxidants cannot suppress the lethal phenotype of a Drosophila model of Huntington's disease
    • Bahadorani S., Hilliker A.J. Antioxidants cannot suppress the lethal phenotype of a Drosophila model of Huntington's disease. Genome 2008, 51:392-395.
    • (2008) Genome , vol.51 , pp. 392-395
    • Bahadorani, S.1    Hilliker, A.J.2
  • 4
    • 33745612296 scopus 로고    scopus 로고
    • Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system
    • Betarbet R., et al. Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system. Neurobiol. Dis. 2006, 22:404-420.
    • (2006) Neurobiol. Dis. , vol.22 , pp. 404-420
    • Betarbet, R.1
  • 5
    • 59349084160 scopus 로고    scopus 로고
    • Post-transcriptional regulation of mRNA associated with DJ-1 in sporadic Parkinson disease
    • Blackinton J., et al. Post-transcriptional regulation of mRNA associated with DJ-1 in sporadic Parkinson disease. Neurosci Lett. 2009, 4521:8-11.
    • (2009) Neurosci Lett. , vol.4521 , pp. 8-11
    • Blackinton, J.1
  • 6
    • 0037428241 scopus 로고    scopus 로고
    • Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
    • Bonifati V., et al. Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 2003, 299:256-259.
    • (2003) Science , vol.299 , pp. 256-259
    • Bonifati, V.1
  • 7
    • 0036123096 scopus 로고    scopus 로고
    • Extension of life span and stress resistance of Drosophila melanogaster by long-term supplementation with melatonin
    • Bonilla E., Medina-Leendertz S., Díaz S. Extension of life span and stress resistance of Drosophila melanogaster by long-term supplementation with melatonin. Exp. Gerontol. 2002, 37:629-638.
    • (2002) Exp. Gerontol. , vol.37 , pp. 629-638
    • Bonilla, E.1    Medina-Leendertz, S.2    Díaz, S.3
  • 8
    • 33845392575 scopus 로고    scopus 로고
    • Paraquat-induced oxidative stress in Drosophila melanogaster: effects of melatonin, glutathione, serotonin, minocycline, lipoic acid and ascorbic acid
    • Bonilla E., Medina-Leendertz S., Villalobos V., Molero L., Bohorquez A. Paraquat-induced oxidative stress in Drosophila melanogaster: effects of melatonin, glutathione, serotonin, minocycline, lipoic acid and ascorbic acid. Neurochem. Res. 2006, 31:1425-1432.
    • (2006) Neurochem. Res. , vol.31 , pp. 1425-1432
    • Bonilla, E.1    Medina-Leendertz, S.2    Villalobos, V.3    Molero, L.4    Bohorquez, A.5
  • 9
    • 0017872475 scopus 로고
    • Microsomal lipid peroxidation
    • Buege J.A., Aust S.D. Microsomal lipid peroxidation. Meth. Enzymol. 1978, 52:302-310.
    • (1978) Meth. Enzymol. , vol.52 , pp. 302-310
    • Buege, J.A.1    Aust, S.D.2
  • 10
    • 2942684871 scopus 로고    scopus 로고
    • The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
    • Canet-Aviles R.M., et al. The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proc. Natl Acad. Sci. USA 2004, 101:9103-9108.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 9103-9108
    • Canet-Aviles, R.M.1
  • 11
    • 20444367300 scopus 로고    scopus 로고
    • Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice
    • Chen L., et al. Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice. J. Biol. Chem. 2005, 280:21418-21426.
    • (2005) J. Biol. Chem. , vol.280 , pp. 21418-21426
    • Chen, L.1
  • 12
    • 33646826619 scopus 로고    scopus 로고
    • Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases
    • Choi J., et al. Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases. J. Biol. Chem. 2006, 281:10816-10824.
    • (2006) J. Biol. Chem. , vol.281 , pp. 10816-10824
    • Choi, J.1
  • 13
    • 10044292870 scopus 로고    scopus 로고
    • Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster
    • Coulom H., Birman S. Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster. J. Neurosci. 2004, 24:10993-10998.
    • (2004) J. Neurosci. , vol.24 , pp. 10993-10998
    • Coulom, H.1    Birman, S.2
  • 14
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's disease: mechanisms and models
    • Dauer W., Przedborski S. Parkinson's disease: mechanisms and models. Neuron 2003, 39:889-909.
    • (2003) Neuron , vol.39 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 15
    • 33846080531 scopus 로고    scopus 로고
    • Oxidative stress mediates tau-induced neurodegeneration in Drosophila
    • Dias-Santagata D., Fulga T.A., Duttaroy A., Feany M.B. Oxidative stress mediates tau-induced neurodegeneration in Drosophila. J. Clin. Invest. 2007, 117:236-245.
    • (2007) J. Clin. Invest. , vol.117 , pp. 236-245
    • Dias-Santagata, D.1    Fulga, T.A.2    Duttaroy, A.3    Feany, M.B.4
  • 16
    • 0033971535 scopus 로고    scopus 로고
    • Avid uptake of linoleic acid and vitamin E by Drosophila melanogaster
    • Draper H.H., Philbrick D.P., Agarwal S., Philips J.P. Avid uptake of linoleic acid and vitamin E by Drosophila melanogaster. Nutr. Res. 2000, 20:113-120.
    • (2000) Nutr. Res. , vol.20 , pp. 113-120
    • Draper, H.H.1    Philbrick, D.P.2    Agarwal, S.3    Philips, J.P.4
  • 17
    • 70349574602 scopus 로고    scopus 로고
    • Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease
    • Faust K., Gehrke S., Yang Y., Yang L., Beal M.F., Lu B. Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease. BMC Neurosci. 2009, 10:109.
    • (2009) BMC Neurosci. , vol.10 , pp. 109
    • Faust, K.1    Gehrke, S.2    Yang, Y.3    Yang, L.4    Beal, M.F.5    Lu, B.6
  • 18
    • 13844253723 scopus 로고    scopus 로고
    • Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1
    • Goldberg M.S., et al. Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1. Neuron 2005, 45:489-496.
    • (2005) Neuron , vol.45 , pp. 489-496
    • Goldberg, M.S.1
  • 19
    • 13044283415 scopus 로고    scopus 로고
    • Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice
    • Gomeza J., et al. Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice. Proc. Natl Acad. Sci. USA 1999, 96:10483-10488.
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 10483-10488
    • Gomeza, J.1
  • 21
    • 67349185546 scopus 로고    scopus 로고
    • Hyperoxia-induced neurodegeneration as a tool to identify neuroprotective genes in Drosophila melanogaster
    • Gruenewald C., Botella J.A., Bayersdorfer F., Navarro J.A., Schneuwly S. Hyperoxia-induced neurodegeneration as a tool to identify neuroprotective genes in Drosophila melanogaster. Free Radical Biol. Med. 2009, 46:1668-1676.
    • (2009) Free Radical Biol. Med. , vol.46 , pp. 1668-1676
    • Gruenewald, C.1    Botella, J.A.2    Bayersdorfer, F.3    Navarro, J.A.4    Schneuwly, S.5
  • 22
    • 0842303109 scopus 로고    scopus 로고
    • Effects of vitamin E on oxidative stress and membrane fluidity in brain of streptozotocin-induced diabetic rats
    • Hong J.H., et al. Effects of vitamin E on oxidative stress and membrane fluidity in brain of streptozotocin-induced diabetic rats. Clin. Chim. Acta 2004, 340:107-115.
    • (2004) Clin. Chim. Acta , vol.340 , pp. 107-115
    • Hong, J.H.1
  • 23
    • 0033556060 scopus 로고    scopus 로고
    • Geroprotector effectiveness of melatonin: investigation of lifespan of Drosophila melanogaster
    • Izmaylov D.M., Obukhova L.K. Geroprotector effectiveness of melatonin: investigation of lifespan of Drosophila melanogaster. Mech. Ageing Dev. 1999, 106:233-240.
    • (1999) Mech. Ageing Dev. , vol.106 , pp. 233-240
    • Izmaylov, D.M.1    Obukhova, L.K.2
  • 24
    • 0342858798 scopus 로고    scopus 로고
    • Oxidative stress during aging of stationary cultures of the yeast Saccharomyces cerevisiae
    • Jakubowski W., Bilinski T., Bartosz G. Oxidative stress during aging of stationary cultures of the yeast Saccharomyces cerevisiae. Free Radical Biol. 2000, 28:659-664.
    • (2000) Free Radical Biol. , vol.28 , pp. 659-664
    • Jakubowski, W.1    Bilinski, T.2    Bartosz, G.3
  • 25
    • 9644289754 scopus 로고    scopus 로고
    • Melatonin, human aging, and age related diseases
    • Karasek M. Melatonin, human aging, and age related diseases. Exp. Gerontol. 2004, 39:1723-1729.
    • (2004) Exp. Gerontol. , vol.39 , pp. 1723-1729
    • Karasek, M.1
  • 26
    • 0032497504 scopus 로고    scopus 로고
    • Parkinson's disease. First of two parts
    • Lang A.E., Lozano A.M. Parkinson's disease. First of two parts. N Engl J. Med. 1998, 339:1044-1053.
    • (1998) N Engl J. Med. , vol.339 , pp. 1044-1053
    • Lang, A.E.1    Lozano, A.M.2
  • 27
    • 34548021452 scopus 로고    scopus 로고
    • Drosophila DJ-1 mutants are sensitive to oxidative stress and show reduced lifespan and motor deficits
    • Lavara-Culebras E., Paricio N. Drosophila DJ-1 mutants are sensitive to oxidative stress and show reduced lifespan and motor deficits. Gene 2007, 400:158-165.
    • (2007) Gene , vol.400 , pp. 158-165
    • Lavara-Culebras, E.1    Paricio, N.2
  • 28
    • 36048965799 scopus 로고    scopus 로고
    • Loss of spastic paraplegia gene atlastin induces age-dependent death of dopaminergic neurons in Drosophila
    • Lee Y., et al. Loss of spastic paraplegia gene atlastin induces age-dependent death of dopaminergic neurons in Drosophila. Neurobiol. Aging 2008, 29:84-94.
    • (2008) Neurobiol. Aging , vol.29 , pp. 84-94
    • Lee, Y.1
  • 30
    • 33344479169 scopus 로고    scopus 로고
    • The effects of exogenous antioxidants on lifespan and oxidative stress resistance in Drosophila melanogaster
    • Magwere T., West M., Riyahi K., Murphy M.P., Smith R.A., Partridge L. The effects of exogenous antioxidants on lifespan and oxidative stress resistance in Drosophila melanogaster. Mech. Ageing Dev. 2006, 127:356-370.
    • (2006) Mech. Ageing Dev. , vol.127 , pp. 356-370
    • Magwere, T.1    West, M.2    Riyahi, K.3    Murphy, M.P.4    Smith, R.A.5    Partridge, L.6
  • 31
    • 24044506249 scopus 로고    scopus 로고
    • Roles of Drosophila DJ-1 in survival of dopaminergic neurons and oxidative stress
    • Menzies F.M., Yenisetti S.C., Min K.T. Roles of Drosophila DJ-1 in survival of dopaminergic neurons and oxidative stress. Curr. Biol. 2005, 15:1578-1582.
    • (2005) Curr. Biol. , vol.15 , pp. 1578-1582
    • Menzies, F.M.1    Yenisetti, S.C.2    Min, K.T.3
  • 32
    • 24044472010 scopus 로고    scopus 로고
    • Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease
    • Meulener M., et al. Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease. Curr. Biol. 2005, 15:1572-1577.
    • (2005) Curr. Biol. , vol.15 , pp. 1572-1577
    • Meulener, M.1
  • 33
    • 33747611218 scopus 로고    scopus 로고
    • Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging
    • Meulener M., Xu K., Thomson L., Ischiropoulos H., Bonini N.M. Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging. Proc. Natl Acad. Sci. USA 2006, 103:12517-12522.
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 12517-12522
    • Meulener, M.1    Xu, K.2    Thomson, L.3    Ischiropoulos, H.4    Bonini, N.M.5
  • 34
    • 0031566231 scopus 로고    scopus 로고
    • DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras
    • Nagakubo D., et al. DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras. Biochem. Biophys. Res. Commun. 1997, 231:509-513.
    • (1997) Biochem. Biophys. Res. Commun. , vol.231 , pp. 509-513
    • Nagakubo, D.1
  • 35
    • 2942528891 scopus 로고    scopus 로고
    • Effects of alpha-tocopherol on an animal model of tauopathies
    • Nakashima H., et al. Effects of alpha-tocopherol on an animal model of tauopathies. Free Radical Biol. Med. 2004, 37:176-186.
    • (2004) Free Radical Biol. Med. , vol.37 , pp. 176-186
    • Nakashima, H.1
  • 36
    • 27144519984 scopus 로고    scopus 로고
    • Drosophila DJ-1 mutants show oxidative stress-sensitive locomotive dysfunction
    • Park J., Kim S.Y., Cha G.H., Lee S.B., Kim S., Chung J. Drosophila DJ-1 mutants show oxidative stress-sensitive locomotive dysfunction. Gene 2005, 361:133-139.
    • (2005) Gene , vol.361 , pp. 133-139
    • Park, J.1    Kim, S.Y.2    Cha, G.H.3    Lee, S.B.4    Kim, S.5    Chung, J.6
  • 38
    • 0036137083 scopus 로고    scopus 로고
    • Effects of pharmacological agents upon a transgenic model of Parkinson's disease in Drosophila melanogaster
    • Pendleton R.G., Parvez F., Sayed M., Hillman R. Effects of pharmacological agents upon a transgenic model of Parkinson's disease in Drosophila melanogaster. J. Pharmacol. Exp. Ther. 2002, 300:91-96.
    • (2002) J. Pharmacol. Exp. Ther. , vol.300 , pp. 91-96
    • Pendleton, R.G.1    Parvez, F.2    Sayed, M.3    Hillman, R.4
  • 39
    • 0031752607 scopus 로고    scopus 로고
    • Vitamin E suppresses generation in vivo and reduces atherosclerosis in ApoE-deficient mice
    • Pratico D., Tangirala R.K., Rader D.J., Rokach J., FitzGerald C.A. Vitamin E suppresses generation in vivo and reduces atherosclerosis in ApoE-deficient mice. Nat. Med. 1998, 4:1189-1192.
    • (1998) Nat. Med. , vol.4 , pp. 1189-1192
    • Pratico, D.1    Tangirala, R.K.2    Rader, D.J.3    Rokach, J.4    FitzGerald, C.A.5
  • 40
    • 33645675839 scopus 로고    scopus 로고
    • Short review on dopamine agonists: insight into clinical and research studies relevant to Parkinson's disease
    • Radad K., Gille G., Rausch W.D. Short review on dopamine agonists: insight into clinical and research studies relevant to Parkinson's disease. Pharmacol. Rep. 2005, 57:701-712.
    • (2005) Pharmacol. Rep. , vol.57 , pp. 701-712
    • Radad, K.1    Gille, G.2    Rausch, W.D.3
  • 41
    • 0035159165 scopus 로고    scopus 로고
    • Vitamin E: protective role of a Janus molecule
    • Ricciarelli R., Zingg J.M., Azzi A. Vitamin E: protective role of a Janus molecule. FASEB J. 2001, 15:2314-2325.
    • (2001) FASEB J. , vol.15 , pp. 2314-2325
    • Ricciarelli, R.1    Zingg, J.M.2    Azzi, A.3
  • 43
    • 51649116692 scopus 로고    scopus 로고
    • Update on the pathogenesis of Parkinson's disease
    • Schultz J.B. Update on the pathogenesis of Parkinson's disease. J. Neurol. 2008, 255(Suppl 5):3-7.
    • (2008) J. Neurol. , vol.255 , Issue.SUPPL. 5 , pp. 3-7
    • Schultz, J.B.1
  • 44
    • 0001898787 scopus 로고    scopus 로고
    • Treatment of central nervous system degeneration disorders
    • McGraw-Hill Companies, New York, G.J. Harman, L.E. Limbird, P.B. Molinoff, R.W. Ruddon, A.G. Gilman (Eds.)
    • Standaert D.J., Young A.B. Treatment of central nervous system degeneration disorders. Goodman & Gilman's The Pharmacological Basis of Therapeutics 1996, 503-519. McGraw-Hill Companies, New York. G.J. Harman, L.E. Limbird, P.B. Molinoff, R.W. Ruddon, A.G. Gilman (Eds.).
    • (1996) Goodman & Gilman's The Pharmacological Basis of Therapeutics , pp. 503-519
    • Standaert, D.J.1    Young, A.B.2
  • 45
    • 24044449234 scopus 로고    scopus 로고
    • Alpha-tocopherol: roles in prevention and therapy of human disease
    • Tucker J.M., Townsend D.M. Alpha-tocopherol: roles in prevention and therapy of human disease. Biomed. Pharmacother. 2005, 59:380-387.
    • (2005) Biomed. Pharmacother. , vol.59 , pp. 380-387
    • Tucker, J.M.1    Townsend, D.M.2
  • 47
    • 48249145149 scopus 로고    scopus 로고
    • RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways
    • Van der Brug M.P., et al. RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways. Proc. Natl Acad. Sci. USA 2008, 105:10244-10249.
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 10244-10249
    • Van der Brug, M.P.1
  • 48
    • 33750840222 scopus 로고    scopus 로고
    • Hypersensitivity to oxygen and shortened lifespan in a Drosophila mitochondrial complex II mutant
    • Walker D.W., et al. Hypersensitivity to oxygen and shortened lifespan in a Drosophila mitochondrial complex II mutant. Proc. Natl Acad. Sci. USA 2006, 103:16382-16387.
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 16382-16387
    • Walker, D.W.1
  • 49
    • 33748600694 scopus 로고    scopus 로고
    • Antioxidants protect PINK1-dependent dopaminergic neurons in Drosophila
    • Wang D., et al. Antioxidants protect PINK1-dependent dopaminergic neurons in Drosophila. Proc. Natl Acad. Sci. USA 2006, 103:13520-13525.
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 13520-13525
    • Wang, D.1
  • 50
    • 38849094086 scopus 로고    scopus 로고
    • Dopamine receptor agonists reverse behavioral abnormalities of alfa-synuclein transgenic mouse, a new model of Parkinson's disease
    • Wakamatsu M., Iwata S., Funakoshi T., Yoshimoto M. Dopamine receptor agonists reverse behavioral abnormalities of alfa-synuclein transgenic mouse, a new model of Parkinson's disease. J. Neurosci. Res. 2008, 86:640-646.
    • (2008) J. Neurosci. Res. , vol.86 , pp. 640-646
    • Wakamatsu, M.1    Iwata, S.2    Funakoshi, T.3    Yoshimoto, M.4
  • 51
    • 26444489693 scopus 로고    scopus 로고
    • Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling
    • Yang Y., et al. Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. Proc. Natl Acad. Sci. USA 2005, 102:13670-13675.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 13670-13675
    • Yang, Y.1
  • 52
    • 31644446112 scopus 로고    scopus 로고
    • Dietary rescue of fumble-a Drosophila model for pantothenate-kinase-associated neurodegeneration
    • Yang Y., Wu Z., Kuo Y.M., Zhou B. Dietary rescue of fumble-a Drosophila model for pantothenate-kinase-associated neurodegeneration. J. Inherit. Metab. Dis. 2005, 28:236-245.
    • (2005) J. Inherit. Metab. Dis. , vol.28 , pp. 236-245
    • Yang, Y.1    Wu, Z.2    Kuo, Y.M.3    Zhou, B.4
  • 53
    • 0842324549 scopus 로고    scopus 로고
    • Antioxidant potential of vitamins A, E and C in modulating oxidative stress in rat brain
    • Zaidi S.M., Banu N. Antioxidant potential of vitamins A, E and C in modulating oxidative stress in rat brain. Clin. Chim. Acta 2004, 340:229-233.
    • (2004) Clin. Chim. Acta , vol.340 , pp. 229-233
    • Zaidi, S.M.1    Banu, N.2
  • 54
    • 54449096831 scopus 로고    scopus 로고
    • Synergistic activation of the human MnSOD promoter by DJ-1 and PGC-1α: regulation by SUMOylation and oxidation
    • Zhong N., Xu J. Synergistic activation of the human MnSOD promoter by DJ-1 and PGC-1α: regulation by SUMOylation and oxidation. Hum. Mol. Genet. 2008, 17:3357-3367.
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 3357-3367
    • Zhong, N.1    Xu, J.2
  • 55
    • 33846254128 scopus 로고    scopus 로고
    • Comparative approaches to facilitate the discovery of prolongevity interventions: effects of tocopherols on lifespan of three invertebrate species
    • Zou S., et al. Comparative approaches to facilitate the discovery of prolongevity interventions: effects of tocopherols on lifespan of three invertebrate species. Mech. Ageing Dev. 2007, 128:222-226.
    • (2007) Mech. Ageing Dev. , vol.128 , pp. 222-226
    • Zou, S.1


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