Hyperoxia-induced neurodegeneration as a tool to identify neuroprotective genes in Drosophila melanogaster

Free Radical Biology and Medicine

Volumn 46, Issue 12, 2009, Pages 1668-1676

  Gruenewald, Christoph ^a   Botella, Jose A ^a   Bayersdorfer, Florian ^a   Navarro, Juan A ^a   Schneuwly, Stephan ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Catalase; Chaperone; Drosophila; Free radicals; Genome wide expression; Hsc70 3; Hsc70 4; Hsp22; Hsp70; Hyperoxia; Neurodegeneration; Oxidative stress; SOD

Indexed keywords

CATALASE; CHAPERONE; COPPER; OXYGEN; SUPEROXIDE DISMUTASE; ZINC;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEGENERATION; CONTROLLED STUDY; DEFENSE MECHANISM; DOPAMINERGIC NERVE CELL; DROSOPHILA MELANOGASTER; GENE EXPRESSION; HYPEROXIA; MALE; MICROARRAY ANALYSIS; MITOCHONDRION; NERVE DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; BRAIN; DROSOPHILA MELANOGASTER; GENES, INSECT; MALE; MOLECULAR CHAPERONES; NERVE DEGENERATION; NEURONS; NEUROPROTECTIVE AGENTS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; OXYGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUPEROXIDE DISMUTASE;

DROSOPHILA MELANOGASTER;

EID: 67349185546     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2009.03.025     Document Type: Article

References (32)

1. Yun S.W., Gerlach M., Riederer P., and Klein M.A. Oxidative stress in the brain at early preclinical stages of mouse scrapie. Exp. Neurol. 201 (2006) 90-98
2. Zhu X., Lee H.G., Perry G., and Smith M.A. Alzheimer disease, the two-hit hypothesis: an update. Biochim. Biophys. Acta 1772 (2007) 494-502
3. Jenner P. Oxidative stress in Parkinson's disease. Ann. Neurol. 53 Suppl. 3 (2003) S26-S36 discussion S36-38
4. Sau D., De Biasi S., Vitellaro-Zuccarello L., Riso P., Guarnieri S., Porrini M., Simeoni S., Crippa V., Onesto E., Palazzolo I., Rusmini P., Bolzoni E., Bendotti C., and Poletti A. Mutation of SOD1 in ALS: a gain of a loss of function. Hum. Mol. Genet. 16 (2007) 1604-1618
5. Trushina E., and McMurray C.T. Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases. Neuroscience 145 (2007) 1233-1248
6. Orr W.C., and Sohal R.S. The effects of catalase gene overexpression on life span and resistance to oxidative stress in transgenic Drosophila melanogaster. Arch. Biochem. Biophys. 297 (1992) 35-41
7. Mockett R.J., Bayne A.C., Kwong L.K., Orr W.C., and Sohal R.S. Ectopic expression of catalase in Drosophila mitochondria increases stress resistance but not longevity. Free Radic. Biol. Med. 34 (2003) 207-217
8. Coulom H., and Birman S. Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster. J. Neurosci. 24 (2004) 10993-10998
9. Girardot F., Monnier V., and Tricoire H. Genome wide analysis of common and specific stress responses in adult Drosophila melanogaster. BMC Genomics 5 (2004) 74
10. Botella J.A., Ulschmid J.K., Gruenewald C., Moehle C., Kretzschmar D., Becker K., and Schneuwly S. The Drosophila carbonyl reductase sniffer prevents oxidative stress-induced neurodegeneration. Curr. Biol. 14 (2004) 782-786
11. Llorens J.V., Navarro J.A., Martinez-Sebastian M.J., Baylies M.K., Schneuwly S., Botella J.A., and Molto M.D. Causative role of oxidative stress in a Drosophila model of Friedreich ataxia. FASEB J. 21 (2007) 333-344
12. Botella J.A., Bayersdorfer F., and Schneuwly S. Superoxide dismutase overexpression protects dopaminergic neurons in a Drosophila model of Parkinson's disease. Neurobiol. Dis. 30 (2008) 65-73
13. Barolo S., Carver L.A., and Posakony J.W. GFP and beta-galactosidase transformation vectors for promoter/enhancer analysis in Drosophila. Biotechniques 29 (2000) 726-732
14. Elefant F., and Palter K.B. Tissue-specific expression of dominant negative mutant Drosophila HSC70 causes developmental defects and lethality. Mol. Biol. Cell 10 (1999) 2101-2117
15. Morrow G., Samson M., Michaud S., and Tanguay R.M. Overexpression of the small mitochondrial Hsp22 extends Drosophila life span and increases resistance to oxidative stress. FASEB J. 18 (2004) 598-599
16. Auluck P.K., Chan H.Y., Trojanowski J.Q., Lee V.M., and Bonini N.M. Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease. Science 295 (2002) 865-868
17. Parkes T.L., Elia A.J., Dickinson D., Hilliker A.J., Phillips J.P., and Boulianne G.L. Extension of Drosophila lifespan by overexpression of human SOD1 in motor neurons. Nat. Genet. 19 (1998) 171-174
18. Phillips J.P., Parkes T.L., and Hilliker A.J. Targeted neuronal gene expression and longevity in Drosophila. Exp. Gerontol. 35 (2000) 1157-1164
19. Friggi-Grelin F., Coulom H., Meller M., Gomez D., Hirsh J., and Birman S. Targeted gene expression in Drosophila dopaminergic cells using regulatory sequences from tyrosine hydroxylase. J. Neurobiol. 54 (2003) 618-627
20. Sohal R.S., Agarwal S., Dubey A., and Orr W.C. Protein oxidative damage is associated with life expectancy of houseflies. Proc. Natl. Acad. Sci. USA 90 (1993) 7255-7259
21. Sohal R.S., Arnold L., and Orr W.C. Effect of age on superoxide dismutase, catalase, glutathione reductase, inorganic peroxides, TBA-reactive material, GSH/GSSG, NADPH/NADP+ and NADH/NAD+ in Drosophila melanogaster. Mech. Ageing Dev. 56 (1990) 223-235
22. Landis G.N., Abdueva D., Skvortsov D., Yang J., Rabin B.E., Carrick J., Tavare S., and Tower J. Similar gene expression patterns characterize aging and oxidative stress in Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 101 (2004) 7663-7668
23. Brand A.H., and Perrimon N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118 (1993) 401-415
24. Cao C., Leng Y., and Kufe D. Catalase activity is regulated by c-Abl and Arg in the oxidative stress response. J. Biol. Chem. 278 (2003) 29667-29675
25. Cadenas E., Mira D., Brunmark A., Lind C., Segura-Aguilar J., and Ernster L. Effect of superoxide dismutase on the autoxidation of various hydroquinones-a possible role of superoxide dismutase as a superoxide:semiquinone oxidoreductase. Free Radic. Biol. Med. 5 (1988) 71-79
26. Okamoto T., Mitsuhashi M., Fujita I., Sindhu R.K., and Kikkawa Y. Induction of cytochrome P450 1A1 and 1A2 by hyperoxia. Biochem. Biophys. Res. Commun. 97 (1993) 878-885
27. Murphy T.C., Amarnath V., and Picklo Sr. M.J. Mitochondrial oxidation of 4-hydroxy-2-nonenal in rat cerebral cortex. J. Neurochem. 84 (2003) 1313-1321
28. Rezk B.M., Haenen G.R., van der Vijgh W.J., and Bast A. Tetrahydrofolate and 5-methyltetrahydrofolate are folates with high antioxidant activity: identification of the antioxidant pharmacophore. FEBS Lett. 555 (2003) 601-605
29. Morrow G., Samson M., Michaud S., and Tanguay R.M. Overexpression of the small mitochondrial Hsp22 extends Drosophila life span and increases resistance to oxidative stress. FASEB J. 18 (2004) 598-599
30. Morrow G., Battistini S., Zhang P., and Tanguay R.M. Decreased lifespan in the absence of expression of the mitochondrial small heat shock protein Hsp22 in Drosophila. J. Biol. Chem. 279 (2004) 43382-43385
31. Klucken J., Shin Y., Masliah E., Hyman B.T., and McLean P.J. Hsp70 reduces alpha-synuclein aggregation and toxicity. J. Biol. Chem. 279 (2004) 25497-25502
32. Nässel D.R., and Elekes K. Aminergic neurons in the brain of blowflies and Drosophila: dopamine- and tyrosine hydroxylase-immunoreactive neurons and their relationship with putative histaminergic neurons. Cell Tissue Res. 267 (1992) 147-167