The mojastin mutant Moj-DM induces apoptosis of the human melanoma SK-Mel-28, but not the mutant Moj-NN nor the non-mutated recombinant Moj-WN

Toxicon

Volumn 56, Issue 3, 2010, Pages 391-401

  Seoane, Agustin I ^a   Tran, Victoria L ^a   Sanchez, Elda E ^b   White, Stephanie A ^a   Choi, Jason L ^a   Gaytán, Brandon ^a   Chavez, Natalie ^a   Reyes, Steven R ^a,b   Ramos, Carla J ^a   Tran, Luan H ^a   Lucena, Sara E ^b   Sugarek, Maria ^b   Perez, John C ^b   Mandal, Stephanie A ^a   Ghorab, Shervin ^a   Rodriguez Acosta, Alexis ^c   Fung, Branden K ^a   Soto, Julio G ^a  

^a SAN JOSE STATE UNIVERSITY   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

^c UNIVERSIDAD CENTRAL DE VENEZUELA   (Venezuela)

Author keywords

Anoikis; Binding loop mutants; Cell adhesion inhibition; Melanoma cell line; Mojastin; Recombinant disintegrin

Indexed keywords

ADENOSINE DIPHOSPHATE; ALPHA6 INTEGRIN; BETA1 INTEGRIN; BETA3 INTEGRIN; CD51 ANTIGEN; DISINTEGRIN; FIBRONECTIN; FLUORESCEIN ISOTHIOCYANATE; GLUTATHIONE TRANSFERASE; INTEGRIN; LIPOCORTIN 5; MOJASTIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

AMINO ACID SUBSTITUTION; APOPTOSIS; ARTICLE; CELL ADHESION; CELL NUCLEUS; CONTROLLED STUDY; CYTOCHEMISTRY; FLUORESCENCE MICROSCOPY; FRAGMENTATION REACTION; HUMAN; HUMAN CELL; IC 50; INHIBITION KINETICS; MELANOMA CELL; MOLECULAR MODEL; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SEQUENCE ALIGNMENT; THROMBOCYTE AGGREGATION INHIBITION; THROMBOCYTE RICH PLASMA;

AMINO ACID SEQUENCE; APOPTOSIS; BASE SEQUENCE; CELL LINE, TUMOR; DISINTEGRINS; DNA PRIMERS; HUMANS; INHIBITORY CONCENTRATION 50; MELANOMA; MOLECULAR SEQUENCE DATA; MUTATION; RECOMBINATION, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 77954144057     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2010.04.002     Document Type: Article

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