Isolation and characterization of two disintegrins inhibiting ADP-induced human platelet aggregation from the venom of Crotalus scutulatus scutulatus (Mohave Rattlesnake)

Toxicology and Applied Pharmacology

Volumn 212, Issue 1, 2006, Pages 59-68

  Sánchez, Elda E ^a   Galán, Jacob A ^a   Russell, William K ^b   Soto, Julio G ^c   Russell, David H ^b   Pérez, John C ^a  

^a TEXAS A AND M UNIVERSITY KINGSVILLE   (United States)

^b Texas AandM University   (United States)

^c SAN JOSE STATE UNIVERSITY   (United States)

Author keywords

Crotalus scutulatus scutulatus; Disintegrins; Fibronectin; Mass spectrometry; Mohave rattlesnake; Mojastin; Mojave rattlesnake; Neurotoxic; T24 cells; Venom

Indexed keywords

ADENOSINE DIPHOSPHATE; CELL ADHESION MOLECULE; DISINTEGRIN; FIBRONECTIN; MOJASTIN 1; MOJASTIN 2; SNAKE VENOM; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; BLADDER CANCER; CANCER CELL; CONTROLLED STUDY; DRUG INHIBITION; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC 50; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN ISOLATION; PROTEIN PURIFICATION; REVERSED PHASE LIQUID CHROMATOGRAPHY; SEQUENCE ANALYSIS; THROMBOCYTE AGGREGATION; UNITED STATES;

ADENOSINE DIPHOSPHATE; ANIMALS; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, ION EXCHANGE; CHROMATOGRAPHY, LIQUID; CROTALID VENOMS; DISINTEGRINS; FIBRINOLYSIS; GELATINASES; HEMORRHAGE; HUMANS; MASS SPECTROMETRY; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; VIPERIDAE;

ARIZONA (SNAKE); ATRACTASPIDIDAE; COLUBRIDAE; CROTALUS ATROX; CROTALUS HORRIDUS; CROTALUS SCUTULATUS; CROTALUS SCUTULATUS SCUTULATUS; ELAPIDAE; SERPENTES; VIPERIDAE;

EID: 33644960024     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2005.07.004     Document Type: Article

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