The snake venom disintegrin salmosin induces apoptosis by disassembly of focal adhesions in bovine capillary endothelial cells

Biochemical and Biophysical Research Communications

Volumn 302, Issue 3, 2003, Pages 502-508

  Hong, Sung Yu ^a   Lee, Hyeryung ^b   You, Weon Kyoo ^b   Chung, Kwang Hoe ^a   Kim, Doo Sik ^b   Song, Kiwon ^b  

^a BioBud Inc   (South Korea)

^b Yonsei University   (South Korea)

Author keywords

Actin cytoskeleton; Apoptosis; Bovine capillary endothelial cell; Disintegrin; Focal adhesion; Focal adhesion kinase; Integrin v 3; Salmosin

Indexed keywords

ACTIN ANTIBODY; ALPHA5 INTEGRIN; BETA CATENIN; BETA3 INTEGRIN; FOCAL ADHESION KINASE; PAXILLIN; POLYCLONAL ANTIBODY; PROTEIN P130; SALMOSIN; SNAKE VENOM; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CAPILLARY ENDOTHELIUM; CELL ACTIVATION; CELL DISRUPTION; CELL MATURATION; CELL PROLIFERATION; CELL SURFACE; CONTACT INHIBITION; CONTROLLED STUDY; CYTOSKELETON; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; FOCAL ADHESION; IMMUNOLOCALIZATION; MICROTUBULE; MICROTUBULE ORGANIZING CENTER; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION;

AGKISTRODON; BOVINAE; GLOYDIUS BLOMHOFFI BREVICAUDUS; GLOYDIUS HALYS; SERPENTES;

EID: 0345269988     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(03)00213-4     Document Type: Article

References (29)

1. Kang I.C., Chung K.H., Lee S.J., Yoon Y.D., Moon H.M., Kim D.S. Purification and molecular cloning of a platelet aggregation inhibitor from the snake (Agkistrodon halys brevicaudus) venom. Thromb. Res. 91:1998;65-73.
2. Kang I.C., Lee Y.D., Kim D.S. A novel disintegrin salmosin inhibits tumor angiogenesis. Cancer Res. 59:1999;3754-3760.
3. Huang S., Chen C.S., Ingber D.E. Control of cyclin D1, p27Kip1, and cell cycle progression in human capillary endothelial cells by cell shape and cytoskeletal tension. Mol. Biol. Cell. 9:1998;3179-3193.
4. Ingber D.E. Fibronectin controls capillary endothelial cell growth by modulating cell shape. Proc. Natl. Acad. Sci. USA. 87:1990;3579-3583.
5. Chen C.S., Mrksich M., Huang S., Whitesides G.M., Ingber D.E. Geometric control or cell life and death. Science. 276:1997;1425-1428.
6. Soszka T., Knudsen K.A., Beviglia L., Poggi A., Niewiarowski S. Inhibition of murine malanoma cell-matrix adhesion and experimental metastasis by albolabrin, an RGD-containing peptide isolated from the venom of Trimeresurus albolabris. Exp. Cell Res. 196:1991;6-12.
7. Parsons J.T., Schaller M.D., Hildebrand J., Leu T.H., Richardson A., Otey C. Focal adhesion kinase: structure and signaling. J. Cell Sci. Suppl. 18:1994;109-113.
8. Hanks S.K., Calalb M.B., Harper M.C., Patel S.K. Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin. Proc. Natl. Acad. Sci. USA. 89:1992;8487-8491.
9. Schaller M.D., Borgman C.A., Cobb B.S., Vines R.R., Reynolds A.B., Parsons J.T. pp125FAK: a structurally distinctive protein-tyrosine kinase associated with focal adhesions. Proc. Natl. Acad. Sci. USA. 89:1992;5192-5196.
10. Yamada K.M., Miyamoto S. Integrin transmembrane signaling and cytoskeletal control. Curr. Opin. Cell Biol. 7:1995;681-689.
11. Craig S.W., Johnson R.P. Assembly of focal adhesions: progress, paradigms and potents. Curr. Opin. Cell Biol. 8:1996;74-85.
12. Lewis J.M., Schwartz M.A. Mapping in vivo associations of cytoplasmic proteins with β1 cytoplasmic domain mutants. Mol. Cell. Biol. 1995;151-160.
13. Schaller M.D., Parsons J.T. Focal adhesion kinase and associated proteins. Curr. Opin. Cell Biol. 6:1994;705-710.
14. cas -binding proteins and their role in cellular transformation Oncogene. 12:1996;2467-2472.
15. CAS signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases Mol. Cell. Biol. 16:1996;2606-2613.
16. CAS, and Nck adaptor proteins Mol. Cell. Biol. 17:1997;1702-1713.
17. Dedhar S., Williarms B., Hannigan G. Integrin-linked kinase (ILK): a regulator of integrin and growth factor signaling. Trends Cell Biol. 9:1999;319-323.
18. Novak A. Cell adhesion and the integrin-linked kinase regulate the LEF-1 and β-catenin signaling pathways. Proc. Natl. Acad. Sci. USA. 95:1998;4374-4379.
19. Hannigan G.E., Leung-Hagesteijn C., Fitz-Gibbon L., Coppolino M.G., Radeva G., Filmus J., Bell J.C., Dedhar S. Regulation of cell adhesion and anchorage-dependent growth by a new β1-integrin-linked protein kinase. Nature. 379:1996;91-96.
20. Marc D., Clara T., Virginia G., Laurent R., James W., Shoukat D. Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase. Proc. Natl. Acad. Sci. USA. 95:1998;11211-11216.
21. Kang I.C., Kim D.S., Jang Y.S., Chung K.H. Suppressive mechanisms of salmosin, a novel disintegrin in B16 melanoma cell metastasis. Biochem. Biophys. Res. Commun. 275:2000;169-173.
22. Lee T., Rhim T., Kim S.S. Prothrombin kringle-2 domain has a growth inhibitory activity against basic fibroblast growth factor-stimulated capillary endothelial cells. J. Biol. Chem. 273:1998;28805-28812.
23. Schaller M.D. Paxillin: a focal adhesion-associated adaptor protein. Oncogene. 20:2001;6459-6472.
24. Wu C., Schukat D. Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrixto actin cytoskeleton and signaling complexes. J. Cell Biol. 155:2001;505-510.
25. Kohler C., Orrenius S., Zhivotovsky B. Evaluation of caspase activity in apoptotic cells. J. Immunol. Methods. 265:2002;97-110.
26. Meredith J.E., Fazeli B., Schwartz M.A. The extracellular matrix as a cell survival factor. Mol. Biol. Cell. 4:1993;953-961.
27. Frisch S.M., Francis H. Disruption of epithelial cell-matrix interactions induces apoptosis. J. Cell Biol. 124:1994;619-626.
28. Frisch S., Vuori K., Ruoslahti E., Chan-Hui P.Y. Control of adhesion-dependent cell survival by focal adhesion kinase. J. Cell Biol. 134:1996;793-799.
29. 3 antagonist and inducing apoptosis Blood. 92:1998;3268-3276.