Generation of robust CD8+ T-cell responses against subdominant epitopes in conserved regions of HIV-1 by repertoire mining with mimotopes

European Journal of Immunology

Volumn 40, Issue 7, 2010, Pages 1950-1962

  Schaubert, Keri L ^a,b   Price, David A ^c,d   Salkowitz, Janelle R ^a   Sewell, Andrew K ^d   Sidney, John ^e   Asher, Tedi E ^c   Blondelle, Sylvie E ^f,g   Adams, Sharon ^h   Marincola, Francesco M ^h   Joseph, Aviva ⁱ   Sette, Alessandro ^e   Douek, Daniel C ^c   Ayyavoo, Velpandi ^j   Storkus, Walter ^k   Leung, Ming Ying ^a   Ng, Hwee L ^l   Yang, Otto O ^l   Goldstein, Harris ⁱ   Wilson, Darcy B ^f,g   Kan Mitchell, June ^a,b  

^a UNIVERSITY OF TEXAS AT EL PASO   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d CARDIFF UNIVERSITY   (United Kingdom)

^e LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^f TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

^g Mixture Sciences Inc   (United States)

^h NATIONAL INSTITUTES OF HEALTH   (United States)

ⁱ ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^j UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^k UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^l UNIVERSITY OF CALIFORNIA   (United States)

more..

Author keywords

Agonist peptide; CD8+ CTL; HIV vaccine; In vitro immunization

Indexed keywords

EPITOPE; HLA A ANTIGEN; HLA A2 ANTIGEN; LYSYLISOLEUCYLASPARAGINYLALANYLTRYPTOPHANYLISOLEUCYLLYSYLVALYLVALINAMIDE; PEPTIDE; PEPTIDE LIBRARY; THREONYLLEUCYLASPARAGINYLALANYLTRYPTOPHANYLVALYLLYSYLVALYLVALINAMIDE; UNCLASSIFIED DRUG; DNA; GAG PROTEIN; HLA-A*02:01 ANTIGEN; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; LYMPHOCYTE ANTIGEN RECEPTOR; P24 PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS TYPE 1; PEPTIDE FRAGMENT; PROTEIN BINDING;

ARTICLE; BINDING AFFINITY; CD8+ T LYMPHOCYTE; CELL CULTURE; CROSS REACTION; CYTOKINE PRODUCTION; CYTOTOXICITY; GENE; GENE SEQUENCE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOGENICITY; NONHUMAN; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TCRB GENE; VIRUS REPLICATION; CELL CLONE; CELL PROLIFERATION; CHEMISTRY; EPITOPE MAPPING; GENETICS; IMMUNOLOGY; METABOLISM; PATHOLOGY; PEPTIDE LIBRARY;

AIDS VACCINES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CLONE CELLS; CONSERVED SEQUENCE; DNA; EPITOPE MAPPING; HIV CORE PROTEIN P24; HIV-1; HLA-A ANTIGENS; HUMANS; PEPTIDE FRAGMENTS; PEPTIDE LIBRARY; PROTEIN BINDING; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; HLA-A2 ANTIGEN;

EID: 77954134978     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200940079     Document Type: Article

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