메뉴 건너뛰기




Volumn 103, Issue 2, 2008, Pages 119-129

The hope for an HIV vaccine based on induction of CD8+ T lymphocytes - A Review

Author keywords

CTL; HIV; SIV; Vaccines

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 42149098328     PISSN: 00740276     EISSN: 16788060     Source Type: Journal    
DOI: 10.1590/S0074-02762008000200001     Document Type: Review
Times cited : (32)

References (78)
  • 2
    • 0347319127 scopus 로고    scopus 로고
    • Impacts of epitope expression kinetics and class I downregulation on the antiviral activity of human immunodeficiency virus type 1-specific cytotoxic T lymphocytes
    • Ali A, Lubong R, Ng H, Brooks DG, Zack JA, Yang OO 2004. Impacts of epitope expression kinetics and class I downregulation on the antiviral activity of human immunodeficiency virus type 1-specific cytotoxic T lymphocytes. J Virol 78: 561-567.
    • (2004) J Virol , vol.78 , pp. 561-567
    • Ali, A.1    Lubong, R.2    Ng, H.3    Brooks, D.G.4    Zack, J.A.5    Yang, O.O.6
  • 14
    • 0028041344 scopus 로고
    • + cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection
    • + cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J Virol 68: 6103-6110.
    • (1994) J Virol , vol.68 , pp. 6103-6110
    • Borrow, P.1    Lewicki, H.2    Hahn, B.H.3    Shaw, G.M.4    Oldstone, M.B.5
  • 16
    • 29244455769 scopus 로고    scopus 로고
    • Casimiro DR, Wang F, Schleif WA, Liang X, Zhang ZQ, Tobery TW, Davies ME, McDermott AB, O'Connor DH, Fridman A, Bagchi A , Tussey LG, Bett AJ, Finnefrock AC, Fu TM, Tang A, Wilson KA, Chen M, Perry HC, Heidecker GJ, Freed DC, Carella A, Punt KS, Sykes KJ, Huang L, Ausensi VI, Bachinsky M, Sadasivan-Nair U, Watkins DI, Emini EA, Shiver JW 2005. Attenuation of simian immunodeficiency virus SIVmac239 infection by prophylactic immunization with dna and recombinant adenoviral vaccine vectors expressing Gag. J Virol 79: 15547-15555.
    • Casimiro DR, Wang F, Schleif WA, Liang X, Zhang ZQ, Tobery TW, Davies ME, McDermott AB, O'Connor DH, Fridman A, Bagchi A , Tussey LG, Bett AJ, Finnefrock AC, Fu TM, Tang A, Wilson KA, Chen M, Perry HC, Heidecker GJ, Freed DC, Carella A, Punt KS, Sykes KJ, Huang L, Ausensi VI, Bachinsky M, Sadasivan-Nair U, Watkins DI, Emini EA, Shiver JW 2005. Attenuation of simian immunodeficiency virus SIVmac239 infection by prophylactic immunization with dna and recombinant adenoviral vaccine vectors expressing Gag. J Virol 79: 15547-15555.
  • 17
    • 0002866386 scopus 로고    scopus 로고
    • Dissecting the multifactorial causes of immunodominance in class I-restricted T cell responses to viruses
    • Chen W, Anton LC, Bennink JR, Yewdell JW 2000. Dissecting the multifactorial causes of immunodominance in class I-restricted T cell responses to viruses. Immunity 12: 83-93.
    • (2000) Immunity , vol.12 , pp. 83-93
    • Chen, W.1    Anton, L.C.2    Bennink, J.R.3    Yewdell, J.W.4
  • 19
    • 0043199284 scopus 로고    scopus 로고
    • How HIV evades CTL recognition
    • Collins KL 2003. How HIV evades CTL recognition. Curr HIV Res 1: 31-40.
    • (2003) Curr HIV Res , vol.1 , pp. 31-40
    • Collins, K.L.1
  • 20
    • 0032556872 scopus 로고    scopus 로고
    • HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes
    • Collins KL, Chen BK, Kalams SA, Walker BD, Baltimore D 1998. HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes. Nature 391: 397-401.
    • (1998) Nature , vol.391 , pp. 397-401
    • Collins, K.L.1    Chen, B.K.2    Kalams, S.A.3    Walker, B.D.4    Baltimore, D.5
  • 24
    • 0036129320 scopus 로고    scopus 로고
    • AIDS vaccine models: Challenging challenge viruses
    • Feinberg MB, Moore JP 2002. AIDS vaccine models: challenging challenge viruses. Nat Med 8: 207-210.
    • (2002) Nat Med , vol.8 , pp. 207-210
    • Feinberg, M.B.1    Moore, J.P.2
  • 32
    • 17144465337 scopus 로고    scopus 로고
    • Horton H, Vogel TU, Carter DK, Vielhuber K, Fuller DH, Shipley T, Fuller JT, Kunstman KJ, Sutter G, Montefiori DC, Erfle V, Desrosiers RC, Wilson N, Picker LJ, Wolinsky SM, Wang C, Allison DB, Watkins DI 2002. Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and reduces initial viral replication but does not prevent disease progression following challenge with pathogenic SIVmac239. J Virol 76: 7187-7202.
    • Horton H, Vogel TU, Carter DK, Vielhuber K, Fuller DH, Shipley T, Fuller JT, Kunstman KJ, Sutter G, Montefiori DC, Erfle V, Desrosiers RC, Wilson N, Picker LJ, Wolinsky SM, Wang C, Allison DB, Watkins DI 2002. Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and reduces initial viral replication but does not prevent disease progression following challenge with pathogenic SIVmac239. J Virol 76: 7187-7202.
  • 34
    • 0037370728 scopus 로고    scopus 로고
    • Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells
    • Kasper MR, Collins KL 2003. Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells. J Virol 77: 3041-3049.
    • (2003) J Virol , vol.77 , pp. 3041-3049
    • Kasper, M.R.1    Collins, K.L.2
  • 35
    • 0025853347 scopus 로고
    • Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes
    • Klotman ME, Kim S, Buchbinder A, DeRossi A, Baltimore D, Wong-Staal F 1991. Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes. Proc Natl Acad Sci U S A 88: 5011-5015.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 5011-5015
    • Klotman, M.E.1    Kim, S.2    Buchbinder, A.3    DeRossi, A.4    Baltimore, D.5    Wong-Staal, F.6
  • 36
    • 0028337166 scopus 로고
    • Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
    • Koup RA, Safrit JT, Cao Y, Andrews CA, McLeod G, Borkowsky W, Farthing C, Ho DD 1994. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J Virol 68: 4650-4655.
    • (1994) J Virol , vol.68 , pp. 4650-4655
    • Koup, R.A.1    Safrit, J.T.2    Cao, Y.3    Andrews, C.A.4    McLeod, G.5    Borkowsky, W.6    Farthing, C.7    Ho, D.D.8
  • 42
    • 0031985775 scopus 로고    scopus 로고
    • Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaques
    • Matano T, Shibata R, Siemon C, Connors M, Lane HC, Martin MA 1998. Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaques. J Virol 72: 164-169.
    • (1998) J Virol , vol.72 , pp. 164-169
    • Matano, T.1    Shibata, R.2    Siemon, C.3    Connors, M.4    Lane, H.C.5    Martin, M.A.6
  • 43
    • 1542287436 scopus 로고    scopus 로고
    • Repeated Low-Dose Mucosal Simian Immunodeficiency Virus SIVmac239 Challenge Results in the Same Viral and Immunological Kinetics as High-Dose Challenge: A Model for the Evaluation of Vaccine Efficacy in Nonhuman Primates
    • McDermott AB, Mitchen J, Piaskowski S, De Souza I, Yant LJ, Stephany J, Furlott J, Watkins DI 2004. Repeated Low-Dose Mucosal Simian Immunodeficiency Virus SIVmac239 Challenge Results in the Same Viral and Immunological Kinetics as High-Dose Challenge: a Model for the Evaluation of Vaccine Efficacy in Nonhuman Primates. J Virol 78: 3140-3144.
    • (2004) J Virol , vol.78 , pp. 3140-3144
    • McDermott, A.B.1    Mitchen, J.2    Piaskowski, S.3    De Souza, I.4    Yant, L.J.5    Stephany, J.6    Furlott, J.7    Watkins, D.I.8
  • 48
    • 0037165969 scopus 로고    scopus 로고
    • Evidence of HIV-1 adaptation to HLA-restricted immune responses at a population level
    • Moore CB, John M, James IR, Christiansen FT, Witt CS, Mallal SA 2002. Evidence of HIV-1 adaptation to HLA-restricted immune responses at a population level. Science 296: 1439-1443.
    • (2002) Science , vol.296 , pp. 1439-1443
    • Moore, C.B.1    John, M.2    James, I.R.3    Christiansen, F.T.4    Witt, C.S.5    Mallal, S.A.6
  • 49
    • 0037321597 scopus 로고    scopus 로고
    • Expression of the major histocompatibility complex class I molecule Mamu-A*01 is associated with control of simian immunodeficiency virus SIVmac239 replication
    • Mothe BR, Weinfurter J, Wang C, Rehrauer W, Wilson N, Allen TM, Allison DB, Watkins DI 2003. Expression of the major histocompatibility complex class I molecule Mamu-A*01 is associated with control of simian immunodeficiency virus SIVmac239 replication. J Virol 77: 2736-2740.
    • (2003) J Virol , vol.77 , pp. 2736-2740
    • Mothe, B.R.1    Weinfurter, J.2    Wang, C.3    Rehrauer, W.4    Wilson, N.5    Allen, T.M.6    Allison, D.B.7    Watkins, D.I.8
  • 50
    • 0037105530 scopus 로고    scopus 로고
    • MHC class I alleles influence set-point viral load and survival time in simian immunodeficiency virus-infected rhesus monkeys
    • Muhl T, Krawczak M, Ten Haaft P, Hunsmann G, Sauermann U 2002. MHC class I alleles influence set-point viral load and survival time in simian immunodeficiency virus-infected rhesus monkeys. J Immunol 169: 3438-3446.
    • (2002) J Immunol , vol.169 , pp. 3438-3446
    • Muhl, T.1    Krawczak, M.2    Ten Haaft, P.3    Hunsmann, G.4    Sauermann, U.5
  • 51
    • 35748968205 scopus 로고    scopus 로고
    • HIV vaccine failure prompts Merck to halt trial
    • NPG, Nature Publishing Group
    • NPG - Nature Publishing Group 2007. HIV vaccine failure prompts Merck to halt trial. Nature 449: 390.
    • (2007) Nature , vol.449 , pp. 390
  • 54
    • 0041707676 scopus 로고    scopus 로고
    • O'Connor DH, Mothe BR, Weinfurter JT, Fuenger S, Rehrauer WM, Jing P, Rudersdorf RR, Liebl ME, Krebs K, Vasquez J, Dodds E, Loffredo J, Martin S, McDermott AB, Allen TM, Wang C, Doxiadis GG, Montefiori DC, Hughes A, Burton DR, Allison DB, Wolinsky SM, Bontrop R, Picker LJ, Watkins DI 2003. Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cytotoxic-T-lymphocyte responses. J Virol 77: 9029-9040.
    • O'Connor DH, Mothe BR, Weinfurter JT, Fuenger S, Rehrauer WM, Jing P, Rudersdorf RR, Liebl ME, Krebs K, Vasquez J, Dodds E, Loffredo J, Martin S, McDermott AB, Allen TM, Wang C, Doxiadis GG, Montefiori DC, Hughes A, Burton DR, Allison DB, Wolinsky SM, Bontrop R, Picker LJ, Watkins DI 2003. Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cytotoxic-T-lymphocyte responses. J Virol 77: 9029-9040.
  • 57
  • 58
    • 0025328383 scopus 로고
    • Cells non-productively infected with HIV-1 exhibit an aberrant pattern of viral RNA expression: A molecular model for latency
    • Pomerantz RJ, Trono D, Feinberg MB, Baltimore D 1990. Cells non-productively infected with HIV-1 exhibit an aberrant pattern of viral RNA expression: a molecular model for latency. Cell 61: 1271-1276.
    • (1990) Cell , vol.61 , pp. 1271-1276
    • Pomerantz, R.J.1    Trono, D.2    Feinberg, M.B.3    Baltimore, D.4
  • 60
    • 0028252718 scopus 로고
    • Expression kinetics and subcellular localization of HIV-1 regulatory proteins Nef, Tat and Rev in acutely and chronically infected lymphoid cell lines
    • Ranki A, Lagerstedt A, Ovod V, Aavik E, Krohn KJ 1994. Expression kinetics and subcellular localization of HIV-1 regulatory proteins Nef, Tat and Rev in acutely and chronically infected lymphoid cell lines. Arch Virol 139: 365-378.
    • (1994) Arch Virol , vol.139 , pp. 365-378
    • Ranki, A.1    Lagerstedt, A.2    Ovod, V.3    Aavik, E.4    Krohn, K.J.5
  • 61
    • 0036227444 scopus 로고    scopus 로고
    • +) T-cell responses is dramatically modified by DNA immunization and is regulated by gamma interferon
    • +) T-cell responses is dramatically modified by DNA immunization and is regulated by gamma interferon. J Virol 76: 4251-4259.
    • (2002) J Virol , vol.76 , pp. 4251-4259
    • Rodriguez, F.1    Harkins, S.2    Slifka, M.K.3    Whitton, J.L.4
  • 64
    • 0037122719 scopus 로고    scopus 로고
    • Shiver JW, Fu TM, Chen L, Casimiro DR, Davies ME, Evans RK, Zhang ZQ, Simon AJ, Trigona WL, Dubey SA, Huang L, Harris VA, Long RS, Liang X, Handt L, Schleif WA, Zhu L, Freed DC, Persaud NV, Guan L, Punt KS, Tang A, Chen M, Wilson KA, Collins KB, Heidecker GJ, Fernandez VR, Perry HC, Joyce JG, Grimm KM, Cook JC, Keller PM, Kresock DS, Mach H, Troutman RD, Isopi LA, Williams DM, Xu Z, Bohannon KE, Volkin DB, Montefiori DC, Miura A, Krivulka GR, Lifton MA, Kuroda MJ, Schmitz JE, Letvin NL, Caulfield MJ, Bett AJ, Youil R, Kaslow DC, Emini EA 2002. Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity. Nature 415: 331-335.
    • Shiver JW, Fu TM, Chen L, Casimiro DR, Davies ME, Evans RK, Zhang ZQ, Simon AJ, Trigona WL, Dubey SA, Huang L, Harris VA, Long RS, Liang X, Handt L, Schleif WA, Zhu L, Freed DC, Persaud NV, Guan L, Punt KS, Tang A, Chen M, Wilson KA, Collins KB, Heidecker GJ, Fernandez VR, Perry HC, Joyce JG, Grimm KM, Cook JC, Keller PM, Kresock DS, Mach H, Troutman RD, Isopi LA, Williams DM, Xu Z, Bohannon KE, Volkin DB, Montefiori DC, Miura A, Krivulka GR, Lifton MA, Kuroda MJ, Schmitz JE, Letvin NL, Caulfield MJ, Bett AJ, Youil R, Kaslow DC, Emini EA 2002. Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity. Nature 415: 331-335.
  • 67
    • 10844279128 scopus 로고    scopus 로고
    • Cutting Edge: Epitope-dependent effect of Nef-mediated HLA class I down-regulation on ability of HIV-1-specific CTLs to suppress HIV-1 replication
    • Tomiyama H, Fujiwara M, Oka S, Takiguchi M 2005. Cutting Edge: Epitope-dependent effect of Nef-mediated HLA class I down-regulation on ability of HIV-1-specific CTLs to suppress HIV-1 replication. J Immunol 174: 36-40.
    • (2005) J Immunol , vol.174 , pp. 36-40
    • Tomiyama, H.1    Fujiwara, M.2    Oka, S.3    Takiguchi, M.4
  • 69
    • 0031903089 scopus 로고    scopus 로고
    • Kinetics of antiviral activity by human immunodeficiency virus type 1-specific cytotoxic T lymphocytes (CTL) and rapid selection of CTL escape virus in vitro
    • van Baalen CA, Schutten M, Huisman RC, Boers PH, Gruters RA, Osterhaus AD 1998. Kinetics of antiviral activity by human immunodeficiency virus type 1-specific cytotoxic T lymphocytes (CTL) and rapid selection of CTL escape virus in vitro. J Virol 72: 6851-6857.
    • (1998) J Virol , vol.72 , pp. 6851-6857
    • van Baalen, C.A.1    Schutten, M.2    Huisman, R.C.3    Boers, P.H.4    Gruters, R.A.5    Osterhaus, A.D.6
  • 71
    • 33744902339 scopus 로고    scopus 로고
    • Wilson NA, Reed J, Napoe GS, Piaskowski S, Szymanski A, Furlott J, Gonzalez EJ, Yant LJ, Maness NJ, May GE, Soma T, Reynolds MR, Rakasz E, Rudersdorf R, McDermott AB, O'Connor DH, Friedrich TC, Allison DB, Patki A, Picker LJ, Burton DR, Lin J, Huang L, Patel D, Heindecker G, Fan J, Citron M, Horton M, Wang F, Liang X, Shiver JW, Casimiro DR, Watkins DI 2006. Vaccine-induced cellular immune responses reduce plasma viral concentrations after repeated low-dose challenge with pathogenic simian immunodeficiency virus SIVmac239. J Virol 80: 5875-5885.
    • Wilson NA, Reed J, Napoe GS, Piaskowski S, Szymanski A, Furlott J, Gonzalez EJ, Yant LJ, Maness NJ, May GE, Soma T, Reynolds MR, Rakasz E, Rudersdorf R, McDermott AB, O'Connor DH, Friedrich TC, Allison DB, Patki A, Picker LJ, Burton DR, Lin J, Huang L, Patel D, Heindecker G, Fan J, Citron M, Horton M, Wang F, Liang X, Shiver JW, Casimiro DR, Watkins DI 2006. Vaccine-induced cellular immune responses reduce plasma viral concentrations after repeated low-dose challenge with pathogenic simian immunodeficiency virus SIVmac239. J Virol 80: 5875-5885.
  • 72
    • 0037301559 scopus 로고    scopus 로고
    • Will we be able to 'spot' an effective HIV-1 vaccine?
    • Yang OO 2003. Will we be able to 'spot' an effective HIV-1 vaccine? Trends Immunol 24: 67-72.
    • (2003) Trends Immunol , vol.24 , pp. 67-72
    • Yang, O.O.1
  • 75
    • 0141886176 scopus 로고    scopus 로고
    • Impacts of avidity and specificity on the antiviral efficiency of HIV-1-specific CTL
    • Yang OO, Sarkis PT, Trocha A, Kalams SA, Johnson RP, Walker BD 2003b. Impacts of avidity and specificity on the antiviral efficiency of HIV-1-specific CTL. J Immunol 171: 3718-3724.
    • (2003) J Immunol , vol.171 , pp. 3718-3724
    • Yang, O.O.1    Sarkis, P.T.2    Trocha, A.3    Kalams, S.A.4    Johnson, R.P.5    Walker, B.D.6
  • 76
    • 33646461679 scopus 로고    scopus 로고
    • The high-frequency major histocompatibility complex class I allele Mamu-B*17 is associated with control of simian immunodeficiency virus SIVmac239 replication
    • Yant LJ, Friedrich TC, Johnson RC, May GE, Maness NJ, Enz AM, Lifson JD, O'Connor DH, Carrington M, Watkins DI 2006. The high-frequency major histocompatibility complex class I allele Mamu-B*17 is associated with control of simian immunodeficiency virus SIVmac239 replication. J Virol 80: 5074-5077.
    • (2006) J Virol , vol.80 , pp. 5074-5077
    • Yant, L.J.1    Friedrich, T.C.2    Johnson, R.C.3    May, G.E.4    Maness, N.J.5    Enz, A.M.6    Lifson, J.D.7    O'Connor, D.H.8    Carrington, M.9    Watkins, D.I.10
  • 77
    • 33749528390 scopus 로고    scopus 로고
    • + T cell responses
    • + T cell responses. Immunity 25: 533-543.
    • (2006) Immunity , vol.25 , pp. 533-543
    • Yewdell, J.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.