-
1
-
-
0037189401
-
Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning
-
Aiuti A, Slavin S, Aker M, et al. 2002. Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning. Science 296: 2410-2413.
-
(2002)
Science
, vol.296
, pp. 2410-2413
-
-
Aiuti, A.1
Slavin, S.2
Aker, M.3
-
2
-
-
67649506317
-
Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1
-
Baek KH, Zaslavsky A, Lynch RC, et al. 2009. Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1. Nature 459: 1126-1130.
-
(2009)
Nature
, vol.459
, pp. 1126-1130
-
-
Baek, K.H.1
Zaslavsky, A.2
Lynch, R.C.3
-
4
-
-
70449427834
-
Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy
-
Cartier N, Hacein-Bey-Abina S, Bartholomae CC, et al. 2009. Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy. Science 326: 818-823.
-
(2009)
Science
, vol.326
, pp. 818-823
-
-
Cartier, N.1
Hacein-Bey-Abina, S.2
Bartholomae, C.C.3
-
5
-
-
54149104472
-
First trimester embryo-fetoscopic and ultrasound-guided fetal blood sampling for ex vivo viral transduction of cultured human fetal mesenchymal stem cells
-
Chan J, Kumar S, Fisk NM. 2008. First trimester embryo-fetoscopic and ultrasound-guided fetal blood sampling for ex vivo viral transduction of cultured human fetal mesenchymal stem cells. Hum Reprod 23: 2427-2437.
-
(2008)
Hum Reprod
, vol.23
, pp. 2427-2437
-
-
Chan, J.1
Kumar, S.2
Fisk, N.M.3
-
6
-
-
12144270060
-
Human fetal mesenchymal stem cells as vehicles for gene delivery
-
Chan J, O'Donoghue K, de la Fuente J, et al. 2005. Human fetal mesenchymal stem cells as vehicles for gene delivery. Stem Cells 23: 93-102.
-
(2005)
Stem Cells
, vol.23
, pp. 93-102
-
-
Chan, J.1
O'Donoghue, K.2
De La Fuente, J.3
-
7
-
-
34147151813
-
Widespread distribution and muscle differentiation of human fetal mesenchymal stem cells after intrauterine transplantation in dystrophic mdx mouse
-
Chan J, Waddington SN, O'Donoghue K, et al. 2007. Widespread distribution and muscle differentiation of human fetal mesenchymal stem cells after intrauterine transplantation in dystrophic mdx mouse. Stem Cells 25: 875-884.
-
(2007)
Stem Cells
, vol.25
, pp. 875-884
-
-
Chan, J.1
Waddington, S.N.2
O'Donoghue, K.3
-
8
-
-
35948979651
-
In vivo use of a nanoknife for axon microsurgery
-
discussion 691-2
-
Chang WC, Hawkes EA, Kliot M, Sretavan DW. 2007. In vivo use of a nanoknife for axon microsurgery. Neurosurgery 61: 683-691 (discussion 691-2).
-
(2007)
Neurosurgery
, vol.61
, pp. 683-691
-
-
Chang, W.C.1
Hawkes, E.A.2
Kliot, M.3
Sretavan, D.W.4
-
9
-
-
10744230959
-
In utero gene therapy rescues vision in a murine model of congenital blindness
-
Dejneka NS, Surace EM, Aleman TS, et al. 2004. In utero gene therapy rescues vision in a murine model of congenital blindness. Mol Ther 9: 182-188.
-
(2004)
Mol Ther
, vol.9
, pp. 182-188
-
-
Dejneka, N.S.1
Surace, E.M.2
Aleman, T.S.3
-
10
-
-
0021888720
-
Treatment of placental vasculature with a neodymium-yttrium-aluminum- garnet laser via fetoscopy
-
DeLia JE, Rogers JG, Dixon JA. 1985. Treatment of placental vasculature with a neodymium-yttrium-aluminum-garnet laser via fetoscopy. Am J Obstet Gynecol 151: 1126-1127.
-
(1985)
Am J Obstet Gynecol
, vol.151
, pp. 1126-1127
-
-
DeLia, J.E.1
Rogers, J.G.2
Dixon, J.A.3
-
11
-
-
0029848406
-
Treatment of X-linked severe combined immunodeficiency by in utero transplantation of paternal bone marrow
-
Flake AW, Roncarolo MG, Puck JM, et al. 1996. Treatment of X-linked severe combined immunodeficiency by in utero transplantation of paternal bone marrow. N Engl J Med 335: 1806-1810.
-
(1996)
N Engl J Med
, vol.335
, pp. 1806-1810
-
-
Flake, A.W.1
Roncarolo, M.G.2
Puck, J.M.3
-
12
-
-
19944421384
-
Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector
-
Gaspar HB, Parsley KL, Howe S, et al. 2004. Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector. Lancet 364: 2181-2187.
-
(2004)
Lancet
, vol.364
, pp. 2181-2187
-
-
Gaspar, H.B.1
Parsley, K.L.2
Howe, S.3
-
13
-
-
0040757845
-
The Frankenstein myth becomes a reality - We have the awful knowledge to make exact copies of human beings
-
Gaylin W. 1972. The Frankenstein myth becomes a reality - we have the awful knowledge to make exact copies of human beings. New York Times Magazine SM12.
-
(1972)
New York Times Magazine SM12
-
-
Gaylin, W.1
-
14
-
-
0029965138
-
Balancing immunity and tolerance: Deleting and tuning lymphocyte repertoires
-
Goodnow CC. 1996. Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires. Proc Natl Acad Sci U S A 93: 2264-2271.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 2264-2271
-
-
Goodnow, C.C.1
-
16
-
-
34447564254
-
Immunomodulation by multipotent mesenchymal stromal cells
-
Gotherstrom C. 2007. Immunomodulation by multipotent mesenchymal stromal cells. Transplantation 84: S35-S37.
-
(2007)
Transplantation
, vol.84
-
-
Gotherstrom, C.1
-
17
-
-
0742304267
-
Immunologic properties of human fetal mesenchymal stem cells
-
Gotherstrom C, Ringden O, Tammik C, Zetterberg E, Westgren M, Le Blanc K. 2004. Immunologic properties of human fetal mesenchymal stem cells. Am J Obstet Gynecol 190: 239-245.
-
(2004)
Am J Obstet Gynecol
, vol.190
, pp. 239-245
-
-
Gotherstrom, C.1
Ringden, O.2
Tammik, C.3
Zetterberg, E.4
Westgren, M.5
Le Blanc, K.6
-
18
-
-
0042168939
-
Immunomodulatory effects of human foetal liver-derived mesenchymal stem cells
-
DOI 10.1038/sj.bmt.1704111
-
Gotherstrom C, Ringden O, Westgren M, Tammik C, Le Blanc K. 2003. Immunomodulatory effects of human foetal liver-derived mesenchymal stem cells. Bone Marrow Transplant 32: 265-272. (Pubitemid 36927077)
-
(2003)
Bone Marrow Transplantation
, vol.32
, Issue.3
, pp. 265-272
-
-
Gotherstrom, C.1
Ringden, O.2
Westgren, M.3
Tammik, C.4
Le Blanc, K.5
-
19
-
-
38949106568
-
Intrauterine transplantation of human fetal mesenchymal stem cells from first trimester blood repairs bone and reduces fractures in osteogenesis imperfecta mice
-
Guillot PV, Abass O, Bassett JH, et al. 2008. Intrauterine transplantation of human fetal mesenchymal stem cells from first trimester blood repairs bone and reduces fractures in osteogenesis imperfecta mice. Blood 111: 1717-1725.
-
(2008)
Blood
, vol.111
, pp. 1717-1725
-
-
Guillot, P.V.1
Abass, O.2
Bassett, J.H.3
-
20
-
-
0037129435
-
Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy
-
Hacein-Bey-Abina S, Le Deist F, Carlier F, et al. 2002. Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy. N Engl J Med 346: 1185-1193.
-
(2002)
N Engl J Med
, vol.346
, pp. 1185-1193
-
-
Hacein-Bey-Abina, S.1
Le Deist, F.2
Carlier, F.3
-
21
-
-
0021343122
-
Phenotypic characterization and ontogeny of mesodermal-derived and endocrine epithelial components of the human thymic micro-environment
-
Haynes BF, Scearce RM, Lobach DF, Hensley LL. 1984. Phenotypic characterization and ontogeny of mesodermal-derived and endocrine epithelial components of the human thymic micro-environment. J Exp Med 159: 1149-1168.
-
(1984)
J Exp Med
, vol.159
, pp. 1149-1168
-
-
Haynes, B.F.1
Scearce, R.M.2
Lobach, D.F.3
Hensley, L.L.4
-
22
-
-
29344466038
-
Controlling tiny multi-scale robots for nerve repair
-
Hogg T, Sretavan DW. 2005. Controlling tiny multi-scale robots for nerve repair. AAAI 1286-1291.
-
(2005)
AAAI
, pp. 1286-1291
-
-
Hogg, T.1
Sretavan, D.W.2
-
23
-
-
85045160359
-
Making babies - The new biology and the 'old' morality
-
Kass L. 1972. Making babies-the new biology and the 'old' morality. Public Interest 26: 18-56.
-
(1972)
Public Interest
, vol.26
, pp. 18-56
-
-
Kass, L.1
-
24
-
-
0032989268
-
An estimated frequency of endogenous insertional mutations in humans
-
Kazazian HH Jr. 1999. An estimated frequency of endogenous insertional mutations in humans. Nat Genet 22: 130-130.
-
(1999)
Nat Genet
, vol.22
, pp. 130-130
-
-
Kazazian Jr., H.H.1
-
25
-
-
53249154636
-
Childhood outcomes after prescription of antibiotics to pregnant women with spontaneous preterm labour: 7-year follow-up of the ORACLE II trial
-
Kenyon S, Pike K, Jones DR, et al. 2008a. Childhood outcomes after prescription of antibiotics to pregnant women with spontaneous preterm labour: 7-year follow-up of the ORACLE II trial. Lancet 372: 1319-1327.
-
(2008)
Lancet
, vol.372
, pp. 1319-1327
-
-
Kenyon, S.1
Pike, K.2
Jones, D.R.3
-
26
-
-
53249140301
-
Childhood outcomes after prescription of antibiotics to pregnant women with preterm rupture of the membranes: 7-year follow-up of the ORACLE I trial
-
Kenyon S, Pike K, Jones DR, et al. 2008b. Childhood outcomes after prescription of antibiotics to pregnant women with preterm rupture of the membranes: 7-year follow-up of the ORACLE I trial. Lancet 372: 1310-1318.
-
(2008)
Lancet
, vol.372
, pp. 1310-1318
-
-
Kenyon, S.1
Pike, K.2
Jones, D.R.3
-
27
-
-
74049098309
-
Chromosome 21-derived microRNAs provide an etiological basis for aberrant protein expression in human Down syndrome brains
-
Kuhn DE, Nuovo GJ, Terry AV Jr, et al. 2010. Chromosome 21- derived microRNAs provide an etiological basis for aberrant protein expression in human Down syndrome brains. J Biol Chem 285: 1529-1543.
-
(2010)
J Biol Chem
, vol.285
, pp. 1529-1543
-
-
Kuhn, D.E.1
Nuovo, G.J.2
Terry Jr., A.V.3
-
28
-
-
20544455396
-
Fetal mesenchymal stem-cell engraftment in bone after in utero transplantation in a patient with severe osteogenesis imperfecta
-
Le Blanc K, Gotherstrom C, Ringden O, et al. 2005. Fetal mesenchymal stem-cell engraftment in bone after in utero transplantation in a patient with severe osteogenesis imperfecta. Transplantation 79: 1607-1614.
-
(2005)
Transplantation
, vol.79
, pp. 1607-1614
-
-
Le Blanc, K.1
Gotherstrom, C.2
Ringden, O.3
-
29
-
-
0033678140
-
Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep
-
Liechty KW, MacKenzie TC, Shaaban AF, et al. 2000. Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep. Nat Med 6: 1282-1286.
-
(2000)
Nat Med
, vol.6
, pp. 1282-1286
-
-
Liechty, K.W.1
MacKenzie, T.C.2
Shaaban, A.F.3
-
30
-
-
0032506669
-
Prenatal diagnosis of fetal RhD status by molecular analysis of maternal plasma
-
DOI 10.1056/NEJM199812103392402
-
Lo YM, Hjelm NM, Fidler C, et al. 1998. Prenatal diagnosis of fetal RhD status by molecular analysis of maternal plasma. N Engl J Med 339: 1734-1738. (Pubitemid 28555431)
-
(1998)
New England Journal of Medicine
, vol.339
, Issue.24
, pp. 1734-1738
-
-
Lo, Y.M.D.1
Hjelm, N.M.2
Fidler, C.3
Sargent, I.L.4
Murphy, M.F.5
Chamberlain, P.F.6
Poon, P.M.K.7
Redman, C.W.G.8
Wainscoat, J.S.9
-
31
-
-
0024331328
-
Prenatal sex determination by DNA amplification from maternal peripheral blood
-
Lo YM, Patel P, Wainscoat JS, Sampietro M, Gillmer MD, Fleming KA. 1989. Prenatal sex determination by DNA amplification from maternal peripheral blood. Lancet 2: 1363-1365. (Pubitemid 20002969)
-
(1989)
Lancet
, vol.2
, Issue.8676
, pp. 1363-1365
-
-
Lo, Y.-M.D.1
Wainscoat, J.S.2
Gillmer, M.D.G.3
Patel, P.4
Sampietro, M.5
Fleming, K.A.6
-
32
-
-
67651091674
-
In utero transplantation of adult bone marrow decreases perinatal lethality and rescues the bone phenotype in the knockin murine model for classical, dominant osteogenesis imperfecta
-
Panaroni C, Gioia R, Lupi A, et al. 2009. In utero transplantation of adult bone marrow decreases perinatal lethality and rescues the bone phenotype in the knockin murine model for classical, dominant osteogenesis imperfecta. Blood 114: 459-468.
-
(2009)
Blood
, vol.114
, pp. 459-468
-
-
Panaroni, C.1
Gioia, R.2
Lupi, A.3
-
33
-
-
40949120900
-
Full-length dystrophin gene transfer to the mdx mouse in utero
-
Reay DP, Bilbao R, Koppanati BM, et al. 2008. Full-length dystrophin gene transfer to the mdx mouse in utero. Gene Ther 15: 531-536.
-
(2008)
Gene Ther
, vol.15
, pp. 531-536
-
-
Reay, D.P.1
Bilbao, R.2
Koppanati, B.M.3
-
35
-
-
0037026891
-
Education and debate: Deaf lesbians, "designer disability," and the future of medicine
-
Savulescu J. 2002. Education and debate: Deaf lesbians, "designer disability," and the future of medicine. BMJ 325: 771-773.
-
(2002)
BMJ
, vol.325
, pp. 771-773
-
-
Savulescu, J.1
-
36
-
-
3042728865
-
Endoscopic laser surgery versus serial amnioreduction for severe twin-to-twin transfusion syndrome
-
Senat MV, Deprest J, Boulvain M, Paupe A, Winer N, Ville Y. 2004. Endoscopic laser surgery versus serial amnioreduction for severe twin-to-twin transfusion syndrome. N Engl J Med 351: 136-144.
-
(2004)
N Engl J Med
, vol.351
, pp. 136-144
-
-
Senat, M.V.1
Deprest, J.2
Boulvain, M.3
Paupe, A.4
Winer, N.5
Ville, Y.6
-
37
-
-
0142181993
-
Long-term correction of bilirubin UDPglucuronyltransferase deficiency in rats by in utero lentiviral gene transfer
-
Seppen J, van der Rijt R, Looije N, van Til NP, Lamers WH, Oude Elferink RP. 2003. Long-term correction of bilirubin UDPglucuronyltransferase deficiency in rats by in utero lentiviral gene transfer. Mol Ther 8: 593-599.
-
(2003)
Mol Ther
, vol.8
, pp. 593-599
-
-
Seppen, J.1
Van Der Rijt, R.2
Looije, N.3
Van Til, N.P.4
Lamers, W.H.5
Oude Elferink, R.P.6
-
38
-
-
77950625195
-
Epigenetic transgenerational actions of environmental factors in disease etiology
-
Skinner MK, Manikkam M, Guerrero-Bosagna C. 2010. Epigenetic transgenerational actions of environmental factors in disease etiology. Trends Endocrinol Metab 21: 214-222.
-
(2010)
Trends Endocrinol Metab
, vol.21
, pp. 214-222
-
-
Skinner, M.K.1
Manikkam, M.2
Guerrero-Bosagna, C.3
-
39
-
-
67249088582
-
Functional genomic analysis of amniotic fluid cell-free mRNA suggests that oxidative stress is significant in Down syndrome fetuses
-
Slonim DK, Koide K, Johnson KL, et al. 2009. Functional genomic analysis of amniotic fluid cell-free mRNA suggests that oxidative stress is significant in Down syndrome fetuses. Proc Natl Acad Sci U S A 106: 9425-9429.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 9425-9429
-
-
Slonim, D.K.1
Koide, K.2
Johnson, K.L.3
-
40
-
-
0029440221
-
Central tolerance of T cells
-
Sprent J. 1995. Central tolerance of T cells. Int Rev Immunol 13: 95-105.
-
(1995)
Int Rev Immunol
, vol.13
, pp. 95-105
-
-
Sprent, J.1
-
41
-
-
33644845679
-
Journey through the thymus: Stromal guides for T-cell development and selection
-
DOI 10.1038/nri1781, PII N1781
-
Takahama Y. 2006. Journey through the thymus: stromal guides for T-cell development and selection. Nat Rev Immunol 6: 127-135. (Pubitemid 43361588)
-
(2006)
Nature Reviews Immunology
, vol.6
, Issue.2
, pp. 127-135
-
-
Takahama, Y.1
-
42
-
-
5444227748
-
Permanent phenotypic correction of hemophilia B in immunocompetent mice by prenatal gene therapy
-
Waddington SN, Nivsarkar MS, Mistry AR, et al. 2004. Permanent phenotypic correction of hemophilia B in immunocompetent mice by prenatal gene therapy. Blood 104: 2714-2721.
-
(2004)
Blood
, vol.104
, pp. 2714-2721
-
-
Waddington, S.N.1
Nivsarkar, M.S.2
Mistry, A.R.3
-
43
-
-
0033552839
-
Gene therapy pushes on, despite doubts
-
Wadman M. 1999. Gene therapy pushes on, despite doubts. Nature 397: 94-94.
-
(1999)
Nature
, vol.397
, pp. 94-94
-
-
Wadman, M.1
-
45
-
-
16144362330
-
In-utero transplantation of parental CD34 haematopoietic progenitor cells in a patient with X-linked severe combined immunodeficiency (SCIDXI)
-
Wengler GS, Lanfranchi A, Frusca T, et al. 1996. In-utero transplantation of parental CD34 haematopoietic progenitor cells in a patient with X-linked severe combined immunodeficiency (SCIDXI). Lancet 348: 1484-1487.
-
(1996)
Lancet
, vol.348
, pp. 1484-1487
-
-
Wengler, G.S.1
Lanfranchi, A.2
Frusca, T.3
-
46
-
-
0036677704
-
Prenatal T-cell reconstitution after in utero transplantation with fetal liver cells in a patient with X-linked severe combined immunodeficiency
-
Westgren M, Ringden O, Bartmann P, et al. 2002. Prenatal T-cell reconstitution after in utero transplantation with fetal liver cells in a patient with X-linked severe combined immunodeficiency. Am J Obstet Gynecol 187: 475-482.
-
(2002)
Am J Obstet Gynecol
, vol.187
, pp. 475-482
-
-
Westgren, M.1
Ringden, O.2
Bartmann, P.3
-
47
-
-
0029983013
-
Lack of evidence of permanent engraftment after in utero fetal stem cell transplantation in congenital hemoglobinopathies
-
Westgren M, Ringden O, Eik-Nes S, et al. 1996. Lack of evidence of permanent engraftment after in utero fetal stem cell transplantation in congenital hemoglobinopathies. Transplantation 61: 1176-1179.
-
(1996)
Transplantation
, vol.61
, pp. 1176-1179
-
-
Westgren, M.1
Ringden, O.2
Eik-Nes, S.3
-
48
-
-
59849114318
-
Superior osteogenic capacity for bone tissue engineering of fetal compared with perinatal and adult mesenchymal stem cells
-
Zhang ZY, Teoh SH, Chong MS, et al. 2009. Superior osteogenic capacity for bone tissue engineering of fetal compared with perinatal and adult mesenchymal stem cells. Stem Cells 27: 126-137.
-
(2009)
Stem Cells
, vol.27
, pp. 126-137
-
-
Zhang, Z.Y.1
Teoh, S.H.2
Chong, M.S.3
|