Circulating leptin and inflammatory response in esophageal cancer, esophageal cancer-related cachexia-anorexia syndrome (CAS) and non-malignant CAS of the alimentary tract

Cytokine

Volumn 51, Issue 2, 2010, Pages 132-137

  Diakowska, Dorota ^a   Krzystek Korpacka, Malgorzata ^a   Markocka Maczka, Krystyna ^a   Diakowski, Witold ^b   Matusiewicz, Malgorzata ^a   Grabowski, Krzysztof ^a  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

^b UNIVERSITY OF WROC AW   (Poland)

Author keywords

Cachexia anorexia syndrome (CAS); Esophageal cancer; Inflammation; Leptin

Indexed keywords

ALBUMIN; C REACTIVE PROTEIN; HEMOGLOBIN; INTERLEUKIN 6; INTERLEUKIN 8; LEPTIN; TUMOR NECROSIS FACTOR ALPHA; SERUM ALBUMIN;

ADULT; AGED; ANOREXIA; ARTICLE; BLOOD SAMPLING; BODY MASS; CACHEXIA; CACHEXIA ANOREXIA SYNDROME; CANCER STAGING; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIGESTIVE SYSTEM; DISEASE ASSOCIATION; DISEASE SEVERITY; DISTANT METASTASIS; DOWN REGULATION; ESOPHAGUS CANCER; FEMALE; HISTOPATHOLOGY; HUMAN; INFLAMMATION; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; NUTRITIONAL STATUS; PREDICTION; PRIORITY JOURNAL; REGIONAL METASTASIS; SEX DIFFERENCE; ADENOCARCINOMA; BLOOD; ESOPHAGUS TUMOR; GASTROINTESTINAL TRACT; METABOLISM; SQUAMOUS CELL CARCINOMA; SYNDROME;

ADENOCARCINOMA; ANOREXIA; BODY MASS INDEX; C-REACTIVE PROTEIN; CACHEXIA; CARCINOMA, SQUAMOUS CELL; DOWN-REGULATION; ESOPHAGEAL NEOPLASMS; FEMALE; GASTROINTESTINAL TRACT; HEMOGLOBINS; HUMANS; INFLAMMATION; INTERLEUKIN-6; INTERLEUKIN-8; LEPTIN; MALE; SERUM ALBUMIN; SYNDROME; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77954086435     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2010.05.006     Document Type: Article

References (46)

1. Plata-Salaman C.R. Central nervous system mechanisms contributing to the cachexia-anorexia syndrome. Nutrition 2000, 16:1009-1012.
2. Saini A., Nassar A., Stewart C.E.H. Waste management - cytokines, growth factors and cachexia. Cytokine Growth Factor Rev 2006, 17:475-486.
3. Buchanan J.B., Johnson R.W. Regulation of food intake by inflammatory cytokines in the brain. Neuroendocrinology 2007, 86:183-190.
4. Burstow M., Kelly T., Panchani S., Khan I.M., Meek D., Memon B., et al. Outcome of palliative esophageal stenting for malignant dysphagia: a retrospective analysis. Dis Esophagus 2009, 22:519-525.
5. Deans D.A.C., Tan B.H., Wigmore S.J., Ross J.A., de Beaux A.C., Paterson-Brown S., et al. The influence of systemic inflammation, dietary intake and stage of disease on rate of weight loss in patients with gastro-oesophageal cancer. Br J Cancer 2009, 100:63-69.
6. Uomo G., Gallucci F., Rabtti P.G. Anorexia-cachexia syndrome in pancreatic cancer: recent development in research and management. JOP 2006, 7:157-162.
7. Lago R., Gomez R., Lago F., Gomez-Reino J., Gualillo O. Leptin beyond body weight regulation-current concepts concerning its role in immune function and inflammation. Cell Immunol 2008, 252:139-145.
8. Horiguchi A., Sumitomo M., Asakuma J., Asano T., Zheng R., Asano T., et al. Increased serum levels and over expression of leptin receptors are associated with the invasion and progression of renal cell carcinoma. J Urol 2006, 176:1631-1635.
9. Karapanagiotou E.M., Tsochatzis E.A., Dilana K.D., Tourkantonis I., Gratsias I., Syrigos K.N. The significance of leptin, adiponectin, and resistin serum levels in non-small cell lung cancer (NSCLC). Lung cancer 2008, 61:391-397.
10. Kerem M., Ferahkose Z., Yilmaz U.T., Pasaoglu H., Ofluoglu E., Bedirli A., et al. Adipokines and ghrelin in gastric cancer cachexia. World J Gastroenterol 2008, 14:3633-3641.
11. Spyridopoulos T.N., Petridou E.T., Dessypris N., Terzidis A., Skalkidou A., Deliveliotis C., et al. Obesity and cancer oncology group. Inverse association of leptin levels with renal cell carcinoma: results from a case-control study. Hormones 2009, 8:39-46.
12. Martignoni M.E., Kunze P., Hildebrandt W., Künzli B., Berberat P., Giese T., et al. Role of mononuclear cells and inflammatory cytokines in pancreatic cancer-related cachexia. Clin Cancer Res 2005, 11:5802-5808.
13. Sobin L.H., Wittekind Ch TNM classification of malignant tumors 2002, springer, berlin. 6th ed.
14. Crumley A.B., McMillan D.C., McKernan M., McDonald A.C., Stuart R.C. Evaluation of an inflammation-based prognostic score in patients with inoperable gastro-esophageal cancer. Br J Cancer 2006, 94:637-641.
15. Gogas H., Trakatelli M., Dessypris N., Terzidis A., Katsambas A., Chrousos G.P., et al. Melanoma risk in association with serum leptin levels and lifestyle parameters: a case-control study. Ann Oncol 2008, 19:384-389.
16. Terzidis A., Sergentanis T.N., Antonopoulos G., Syrigos C., Efremidis A., Polyzos A., et al. Elevated serum leptin levels: a risk factor for non-small-cell lung cancer?. Oncology 2009, 76:19-25.
17. Wu M.H., Chou Y.C., Chou W.Y., Hsu G.C., Chu C.H., Yu C.P., et al. Circulating levels of leptin, adiposity and breast cancer risk. Br J Cancer 2009, 100:578-582.
18. Wallace A.M., Kelly A., Sattar N., McArdle C.S., McMillan D.C. Circulating concentrations of " free" leptin in relation to fat mass and appetite in gastrointestinal cancer patients. Nutr Cancer 2002, 44:156-160.
19. Dülger H., Alici S., Sekeroĝlu M.R., Erkog R., Ozbek H., Noyan T., et al. Serum levels of leptin and proinflammatory cytokines in patients with gastrointestinal cancer. Int J Clin Pract 2004, 58:545-549.
20. Brown D.R., Berkowitz D.E., Breslow M.J. Weight loss is not associated with hyperleptinemia in humans with pancreatic cancer. J Clin Endocrinol Metab 2001, 86:162-166.
21. Tas F., Duranyildiz D., Argon A., Oguz H., Camlica H., Yasasever V., et al. Serum levels of leptin and proinflammatory cytokines in advanced-stage non-small cell lung cancer. Med Oncol 2005, 22:353-358.
22. Loberg R.D., Bradley D.A., Tomlins S.A., Chinnaiyan A.M., Pienta K.J. The lethal phenotype of cancer: the molecular basis of death due to malignancy. CA Cancer J Clin 2007, 57:225-241.
23. Cheung W., Yu P.X., Little B.M., Cone R.D., Marks D.L., Mak R.H. Role of leptin and melanocortin signaling in uremia-associated cachexia. J Clin Invest 2005, 115:1659-1665.
24. Eckert E.D., Pomeroy C., Raymond N., Kohler P.F., Thuras P., Bowers C.Y. Leptin in anorexia nervosa. J Clin Endocrinol Metab 1998, 83:791-795.
25. Lieffers J.R., Mourtzakis M., Hall K.D., McCargar L.J., Prado C.M.M., Baracos V.E. A viscerally driven cachexia syndrome in patients with advanced colorectal cancer: contributions of organ and tumor mass to whole-body energy demands. Am J Clin Nutr 2009, 89:1173-1179.
26. Wallace A.M., Sattar N., McMillan D.C. Effect of weight loss and the inflammatory response on leptin concentrations in gastrointestinal cancer patients. Clin Cancer Res 1998, 4:2977-2979.
27. Alemán M.R., Santolaria F., Batista N., de La Vega M., González-Reimers E., Milena A., et al. Leptin role in advanced lung cancer. A mediator of the acute phase response or a marker of the status of nutrition?. Cytokine 2002, 19:21-26.
28. Pajak B., Orzechowska S., Pijet B., Pijet M., Pogorzelska A., Gajkowska B., et al. Crossroads of cytokine signaling-the chase to stop muscle cachexia. J Physiol Pharmacol 2008, 59(Suppl 9):251-264.
29. Konopleva M., Mikhail A., Estrov Z., Zhao S., Harris D., Sanchez-Williams G., et al. Expression and function of leptin receptor isoforms in myeloid leukemia and myelodysplastic syndromes: proliferative and anti-apoptotic activities. Blood 1999, 93:1668-1676.
30. Sierra-Honigmann M.R., Nath A.K., Murakami C., García-Cardeña G., Papapetropoulos A., Sessa W.C., et al. Biological action of leptin as an angiogenic factor. Science 1998, 281:1683-1695.
31. Frankenberry K.A., Somasundar P., McFadden D.W., Vona-Davis L.C. Leptin induces cell migration and the expression of growth factors in human prostate cancer cells. Am J Surg 2004, 188:560-565.
32. Zhou J., Lei W., Shen L., Luo H.-S., Shen Z.-X. Primary study of leptin and human hepatocellular carcinoma in vitro. World J Gastroenterol 2008, 14:2900-2904.
33. Somasundar P., Riggs D., Jackson B., Vona-Davis L., McFadden D.W. Leptin stimulates esophageal adenocarcinoma growth by nonapoptotic mechanisms. Am J Surg 2003, 186:575-578.
34. Zhao X., Huang K., Zhu Z., Chen S., Hu R. Correlation between expression of leptin and clinicopathological features and prognosis in patients with gastric cancer. J Gastroenterol Hepatol 2007, 22:1317-1321.
35. Wolf I., Sadetzki S., Kanety H., Kundel Y., Pariente C., Epstein N., et al. Adiponectin, ghrelin, and leptin in cancer cachexia in breast and colon cancer patients. Cancer 2006, 106:966-973.
36. Casabiell X., Piñeiro V., Peino R., Lage M., Camiña J., Gallego R., et al. Gender differences in both spontaneous and stimulated leptin secretion by human omental adipose tissue in vitro: dexametha-sone and estradiol stimulate leptin release in women, but not in men. J Clin Endocrinol Metab 1998, 83:2149-2155.
37. Wei Nathan, ; accessed on 13.07.2009. http://www.arthritis-treatment-and-relief.com/plasma-cytokines-half-life.html.
38. Krzystek-Korpacka M., Matusiewicz M., Diakowska D., Grabowski K., Blachut K., Kustrzeba-Wojcicka I., et al. Impact of weight loss on circulating IL-1, IL-6, IL-8, TNF-alpha, VEGF-A, VEGF-C and midkine in gastroesophageal cancer patients. Clin Biochem 2007, 40:1353-1360.
39. Maguire R., McMillan D.C., Wallace A.M., McArdle C. A longitudinal study of leptin and appetite, resting energy expenditure and body fat mass in weight-stable cancer patients. Cytokine 2002, 20:174-177.
40. Araújo J.P., Lourenço P., Rocha-Gonçalves F., Ferreira A., Bettencourt P. Adiponectin is increased in cardiac cachexia irrespective of body mass index. Eur J Heart Fail 2009, 11:567-572.
41. Dowidar N.L., Dejong C.H.C., Fearson K.C.H., Garden O.J., Ross J.A. Effects of leptin on isolated human hepatocyte C reactive protein production. Eur J Gastroenterol Hepatol 2000, 12:A18.
42. Shamsuzzaman A.S., Winnicki M., Wolk R., Svatikova A., Phillips B.G., Davison D.E., et al. Independent association between plasma leptin and CRP in healthy humans. Circulation 2004, 109:2181-2185.
43. Ble A., Windham B.G., Bandinelli S., Taub D.D., Volpato S., Bartali B., et al. Relation of plasma leptin to C-reactive protein in older adults. Am J Cardiol 2005, 96:991-995.
44. Krzystek-Korpacka M., Matusiewicz M., Diakowska D., Grabowski K., Blachut K., Kustrzeba-Wojcicka I., et al. Acute-phase response proteins are related to cachexia and accelerated angiogenesis in gastroesophageal cancers. Clin Chem Lab Med 2008, 46:359-364.
45. Mantovani G., Maccio A., Mura L., Massa E., Mudu M.C., Mulas C., et al. Serum levels of leptin and proinflammatory cytokines in patients with advanced-stage cancer at different sites. J Mol Med 2000, 78:554-561.
46. Krzystek-Korpacka M., Matusiewicz M., Diakowska D., Grabowski K., Blachut K., Konieczny D., et al. Elevation of circulating interleukin-8 is related to lymph node and distant metastases in esophageal squamous cell carcinomas-implication for clinical evaluation of cancer patient. Cytokine 2008, 41:232-239.