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Volumn 76, Issue 9, 2008, Pages 4241-4250

The absence of cutaneous lymph nodes results in a Th2 response and increased susceptibility to Leishmania major infection in mice

Author keywords

[No Author keywords available]

Indexed keywords

LYMPHOTOXIN; LYMPHOTOXIN BETA; LYMPHOTOXIN BETA RECEPTOR;

EID: 51949116278     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.01714-07     Document Type: Article
Times cited : (25)

References (43)
  • 2
    • 0035871627 scopus 로고    scopus 로고
    • The role of dendritic cells, B cells, and M cells in gut-oriented immune responses
    • Alpan, O., G. Rudomen, and P. Matzinger. 2001. The role of dendritic cells, B cells, and M cells in gut-oriented immune responses. J. Immunol. 166: 4843-852.
    • (2001) J. Immunol , vol.166 , pp. 4843-4852
    • Alpan, O.1    Rudomen, G.2    Matzinger, P.3
  • 3
    • 0034661692 scopus 로고    scopus 로고
    • A natural model of Leishmania major infection reveals a prolonged "silent" phase of parasite amplification in the skin before the onset of lesion formation and immunity
    • Belkaid, Y., S. Mendez, R. Lira, N. Kadambi, G. Milon, and D. Sacks. 2000. A natural model of Leishmania major infection reveals a prolonged "silent" phase of parasite amplification in the skin before the onset of lesion formation and immunity. J. Immunol. 165:969-977.
    • (2000) J. Immunol , vol.165 , pp. 969-977
    • Belkaid, Y.1    Mendez, S.2    Lira, R.3    Kadambi, N.4    Milon, G.5    Sacks, D.6
  • 4
    • 0037090268 scopus 로고    scopus 로고
    • CD8+ T cells are required for primary immunity in C57BL/6 mice following low-dose, intradermal challenge with Leishmania major
    • Belkaid, Y., E. von Stebut, S. Mendez, R. Lira, E. Caler, S. Bertholet, M. C. Udey, and D. Sacks. 2002. CD8+ T cells are required for primary immunity in C57BL/6 mice following low-dose, intradermal challenge with Leishmania major. J. Immunol. 168:3992-4000.
    • (2002) J. Immunol , vol.168 , pp. 3992-4000
    • Belkaid, Y.1    von Stebut, E.2    Mendez, S.3    Lira, R.4    Caler, E.5    Bertholet, S.6    Udey, M.C.7    Sacks, D.8
  • 7
    • 0037884699 scopus 로고    scopus 로고
    • The lymphotoxin beta receptor is critically involved in controlling infections with the intracellular pathogens Mycobacterium tuberculosis and Listeria monocytogenes
    • Ehlers, S., C. Holscher, S. Scheu, C. Tertilt, T. Hehlgans, J. Suwinski, R. Endres, and K. Pfeffer. 2003. The lymphotoxin beta receptor is critically involved in controlling infections with the intracellular pathogens Mycobacterium tuberculosis and Listeria monocytogenes. J. Immunol. 170:5210-5218.
    • (2003) J. Immunol , vol.170 , pp. 5210-5218
    • Ehlers, S.1    Holscher, C.2    Scheu, S.3    Tertilt, C.4    Hehlgans, T.5    Suwinski, J.6    Endres, R.7    Pfeffer, K.8
  • 10
    • 0033521542 scopus 로고    scopus 로고
    • Mature follicular dendritic ceil networks depend on expression of lymphotoxin beta receptor by radioresistant stromal cells and of lymphotoxin beta and tumor necrosis factor by B cells
    • Endres, R., M. B. Alimzhanov, T. Plitz, A. Futterer, M. H. Kosco-Vilbois, S. A. Nedospasov, K. Rajewsky, and K. Pfeffer. 1999. Mature follicular dendritic ceil networks depend on expression of lymphotoxin beta receptor by radioresistant stromal cells and of lymphotoxin beta and tumor necrosis factor by B cells. J. Exp. Med. 189:159-168.
    • (1999) J. Exp. Med , vol.189 , pp. 159-168
    • Endres, R.1    Alimzhanov, M.B.2    Plitz, T.3    Futterer, A.4    Kosco-Vilbois, M.H.5    Nedospasov, S.A.6    Rajewsky, K.7    Pfeffer, K.8
  • 11
    • 0033006011 scopus 로고    scopus 로고
    • Development and maturation of secondary lymphoid tissues
    • Fu, Y. X., and D. D. Chaplin. 1999. Development and maturation of secondary lymphoid tissues. Annu. Rev. Immunol. 17:399-433.
    • (1999) Annu. Rev. Immunol , vol.17 , pp. 399-433
    • Fu, Y.X.1    Chaplin, D.D.2
  • 12
    • 0032127301 scopus 로고    scopus 로고
    • The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues
    • Futterer, A., K. Mink, A. Luz, M. H. Kosco-Vilbois, and K. Pfeffer. 1998. The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues. Immunity 9:59-70.
    • (1998) Immunity , vol.9 , pp. 59-70
    • Futterer, A.1    Mink, K.2    Luz, A.3    Kosco-Vilbois, M.H.4    Pfeffer, K.5
  • 13
    • 0035139983 scopus 로고    scopus 로고
    • Danger signals: SOS to the immune system
    • Gallucci, S., and P. Matzinger. 2001. Danger signals: SOS to the immune system. Curr. Opin. Immunol. 13:114-119.
    • (2001) Curr. Opin. Immunol , vol.13 , pp. 114-119
    • Gallucci, S.1    Matzinger, P.2
  • 15
    • 33745810574 scopus 로고    scopus 로고
    • Lymph node resident rather than skin-derived dendritic cells initiate specific T cell responses after Leishmania major infection
    • Iezzi, G., A. Frohlich, B. Ernst, F. Ampenberger, S. Saeland, N. Glaichen-haus, and M. Kopf. 2006. Lymph node resident rather than skin-derived dendritic cells initiate specific T cell responses after Leishmania major infection. J. Immunol. 177:1250-1256.
    • (2006) J. Immunol , vol.177 , pp. 1250-1256
    • Iezzi, G.1    Frohlich, A.2    Ernst, B.3    Ampenberger, F.4    Saeland, S.5    Glaichen-haus, N.6    Kopf, M.7
  • 16
    • 0033486007 scopus 로고    scopus 로고
    • T-cell priming by type-1 and type-2 polarized dendritic cells: The concept of a third signal
    • Kalinski, P., C. M. Hilkens, E. A. Wierenga, and M. L. Kapsenberg. 1999. T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal. Immunol. Today 20:561-567.
    • (1999) Immunol. Today , vol.20 , pp. 561-567
    • Kalinski, P.1    Hilkens, C.M.2    Wierenga, E.A.3    Kapsenberg, M.L.4
  • 17
    • 0033103158 scopus 로고    scopus 로고
    • Lymph node germinal centers form in the absence of follicular dendritic cell networks
    • Koni, P. A., and R. A. Flavell. 1999. Lymph node germinal centers form in the absence of follicular dendritic cell networks. J. Exp. Med. 189:855-864.
    • (1999) J. Exp. Med , vol.189 , pp. 855-864
    • Koni, P.A.1    Flavell, R.A.2
  • 18
    • 0032759847 scopus 로고    scopus 로고
    • TNF and lymphotoxin beta cooperate in the maintenance of secondary lymphoid tissue microarchitecture but not in the development of lymph nodes
    • Kuprash, D. V., M. B. Alimzhanov, A. V. Tumanov, A. O. Anderson, K. Pfeffer, and S. A. Nedospasov. 1999. TNF and lymphotoxin beta cooperate in the maintenance of secondary lymphoid tissue microarchitecture but not in the development of lymph nodes. J. Immunol. 163:6575-6580.
    • (1999) J. Immunol , vol.163 , pp. 6575-6580
    • Kuprash, D.V.1    Alimzhanov, M.B.2    Tumanov, A.V.3    Anderson, A.O.4    Pfeffer, K.5    Nedospasov, S.A.6
  • 19
    • 0034088031 scopus 로고    scopus 로고
    • Immunologic 'ignorance' of vascularized organ transplants in the absence of secondary lymphoid tissue
    • Lakkis, F. G., A. Arakelov, B. T. Konieczny, and Y. Inoue. 2000. Immunologic 'ignorance' of vascularized organ transplants in the absence of secondary lymphoid tissue. Nat. Med. 6:686-688.
    • (2000) Nat. Med , vol.6 , pp. 686-688
    • Lakkis, F.G.1    Arakelov, A.2    Konieczny, B.T.3    Inoue, Y.4
  • 20
    • 0029166460 scopus 로고
    • Early parasite containment is decisive for resistance to Leishmania major infection
    • Laskay, T., A. Diefenbach, M. Rollinghoff, and W. Solbach. 1995. Early parasite containment is decisive for resistance to Leishmania major infection. Eur. J. Immunol. 25:2220-2227.
    • (1995) Eur. J. Immunol , vol.25 , pp. 2220-2227
    • Laskay, T.1    Diefenbach, A.2    Rollinghoff, M.3    Solbach, W.4
  • 21
    • 0032480316 scopus 로고    scopus 로고
    • Turning off follicular dendritic cells
    • Mackay, F., and J. L. Browning. 1998. Turning off follicular dendritic cells. Nature 395:26-27.
    • (1998) Nature , vol.395 , pp. 26-27
    • Mackay, F.1    Browning, J.L.2
  • 22
    • 1642303398 scopus 로고    scopus 로고
    • Two waves of antigen-containing dendritic cells in vivo in experimental Leishmania major infection
    • Misslitz, A. C., K. Bonhagen, D. Harbecke, C. Lippuner, T. Kamradt, and T. Aebischer. 2004. Two waves of antigen-containing dendritic cells in vivo in experimental Leishmania major infection. Eur. J. Immunol. 34:715-725.
    • (2004) Eur. J. Immunol , vol.34 , pp. 715-725
    • Misslitz, A.C.1    Bonhagen, K.2    Harbecke, D.3    Lippuner, C.4    Kamradt, T.5    Aebischer, T.6
  • 23
    • 0029557947 scopus 로고
    • The influence of the site of parasite inoculation on the development of Th1 and Th2 type immune responses in (BALB/c x C57BL/6) F1 mice infected with Leishmania major
    • Nabors, G. S., T. Nolan, W. Croop, J. Li, and J. P. Farrell. 1995. The influence of the site of parasite inoculation on the development of Th1 and Th2 type immune responses in (BALB/c x C57BL/6) F1 mice infected with Leishmania major. Parasite Immunol. 17:569-579.
    • (1995) Parasite Immunol , vol.17 , pp. 569-579
    • Nabors, G.S.1    Nolan, T.2    Croop, W.3    Li, J.4    Farrell, J.P.5
  • 24
    • 0020074176 scopus 로고
    • Mechanisms of immunity to leishmaniasis. IV. Significance of lymphatic drainage from the site of infection
    • Poulter, L. W., and C. R. Pandolph. 1982. Mechanisms of immunity to leishmaniasis. IV. Significance of lymphatic drainage from the site of infection. Clin. Exp. Immunol. 48:396-402.
    • (1982) Clin. Exp. Immunol , vol.48 , pp. 396-402
    • Poulter, L.W.1    Pandolph, C.R.2
  • 25
    • 0028933795 scopus 로고
    • The regulation of immunity to Leishmania major
    • Reiner, S. L., and R. M. Locksley. 1995. The regulation of immunity to Leishmania major. Annu. Rev. Immunol. 13:151-177.
    • (1995) Annu. Rev. Immunol , vol.13 , pp. 151-177
    • Reiner, S.L.1    Locksley, R.M.2
  • 26
    • 0030864294 scopus 로고    scopus 로고
    • Selective disruption of lymphotoxin ligands reveals a novel set of mucosal lymph nodes and unique effects on lymph node cellular organization
    • Rennert, P. D., J. L. Browning, and P. S. Hochman. 1997. Selective disruption of lymphotoxin ligands reveals a novel set of mucosal lymph nodes and unique effects on lymph node cellular organization. Int. Immunol. 9:1627-1639.
    • (1997) Int. Immunol , vol.9 , pp. 1627-1639
    • Rennert, P.D.1    Browning, J.L.2    Hochman, P.S.3
  • 27
    • 0029844961 scopus 로고    scopus 로고
    • Surface lymphotoxin alpha/beta complex is required for the development of peripheral lymphoid organs
    • Rennert, P. D., J. L. Browning, R. Mebius, F. Mackay, and P. S. Hochman. 1996. Surface lymphotoxin alpha/beta complex is required for the development of peripheral lymphoid organs. J. Exp. Med. 184:1999-2006.
    • (1996) J. Exp. Med , vol.184 , pp. 1999-2006
    • Rennert, P.D.1    Browning, J.L.2    Mebius, R.3    Mackay, F.4    Hochman, P.S.5
  • 28
    • 0035806245 scopus 로고    scopus 로고
    • Essential role of lymph nodes in contact hypersensitivity revealed in lymphotoxin-alpha-deficient mice
    • Rennert, P. D., P. S. Hochman, R. A. Flavell, D. D. Chaplin, S. Jayaraman, J. L. Browning, and Y. X. Fu. 2001. Essential role of lymph nodes in contact hypersensitivity revealed in lymphotoxin-alpha-deficient mice. J. Exp. Med. 193:1227-1238.
    • (2001) J. Exp. Med , vol.193 , pp. 1227-1238
    • Rennert, P.D.1    Hochman, P.S.2    Flavell, R.A.3    Chaplin, D.D.4    Jayaraman, S.5    Browning, J.L.6    Fu, Y.X.7
  • 29
    • 0032127288 scopus 로고    scopus 로고
    • Lymph node genesis is induced by signaling through the lymphotoxin beta receptor
    • Rennert, P. D., D. James, F. Mackay, J. L. Browning, and P. S. Hochman. 1998. Lymph node genesis is induced by signaling through the lymphotoxin beta receptor. Immunity 9:71-79.
    • (1998) Immunity , vol.9 , pp. 71-79
    • Rennert, P.D.1    James, D.2    Mackay, F.3    Browning, J.L.4    Hochman, P.S.5
  • 30
    • 0041850023 scopus 로고    scopus 로고
    • Analysis of the maturation process of dendritic cells deficient for TNF and lymphotoxin-alpha reveals an essential role for TNF
    • Ritter, U., A. Meissner, J. Ott, and H. Korner. 2003. Analysis of the maturation process of dendritic cells deficient for TNF and lymphotoxin-alpha reveals an essential role for TNF. J. Leukoc. Biol. 74:216-222.
    • (2003) J. Leukoc. Biol , vol.74 , pp. 216-222
    • Ritter, U.1    Meissner, A.2    Ott, J.3    Korner, H.4
  • 31
    • 3242679958 scopus 로고    scopus 로고
    • CD8 alpha- and Langerin-negative dendritic cells, but not Langerhans cells, act as principal antigen-presenting cells in leishmaniasis
    • Ritter, U., A. Meissner, C. Scheidig, and H. Korner. 2004. CD8 alpha- and Langerin-negative dendritic cells, but not Langerhans cells, act as principal antigen-presenting cells in leishmaniasis. Eur. J. Immunol. 34:1542-1550.
    • (2004) Eur. J. Immunol , vol.34 , pp. 1542-1550
    • Ritter, U.1    Meissner, A.2    Scheidig, C.3    Korner, H.4
  • 32
    • 0036831673 scopus 로고    scopus 로고
    • The immunology of susceptibility and resistance to Leishmania major in mice
    • Sacks, D., and N. Noben-Trauth. 2002. The immunology of susceptibility and resistance to Leishmania major in mice. Nat. Rev. Immunol. 2:845-858.
    • (2002) Nat. Rev. Immunol , vol.2 , pp. 845-858
    • Sacks, D.1    Noben-Trauth, N.2
  • 33
    • 0033830087 scopus 로고    scopus 로고
    • In experimental leishmaniasis deficiency of CD18 results in parasite dissemination associated with altered macrophage functions and incomplete Th1 cell response
    • Schonlau, F., K. Scharffetter-Kochanek, S. Grabbe, B. Pietz, C. Sorg, and C. Sunderkotter. 2000. In experimental leishmaniasis deficiency of CD18 results in parasite dissemination associated with altered macrophage functions and incomplete Th1 cell response. Eur. J. Immunol. 30:2729-2740.
    • (2000) Eur. J. Immunol , vol.30 , pp. 2729-2740
    • Schonlau, F.1    Scharffetter-Kochanek, K.2    Grabbe, S.3    Pietz, B.4    Sorg, C.5    Sunderkotter, C.6
  • 34
    • 27744592020 scopus 로고    scopus 로고
    • Role of lymphotoxin in experimental models of infectious diseases: Potential benefits and risks of a therapeutic inhibition of the lymphotoxin-β receptor pathway
    • Spahn, T. W., H. P. Eugster, A. Fontana, W. Domschke, and T. Kucharzik. 2005. Role of lymphotoxin in experimental models of infectious diseases: potential benefits and risks of a therapeutic inhibition of the lymphotoxin-β receptor pathway. Infect. Immun. 73:7077-7088.
    • (2005) Infect. Immun , vol.73 , pp. 7077-7088
    • Spahn, T.W.1    Eugster, H.P.2    Fontana, A.3    Domschke, W.4    Kucharzik, T.5
  • 35
    • 0032736525 scopus 로고    scopus 로고
    • Decreased severity of myelin oligodendrocyte glycoprotein peptide 33-35-induced experimental autoimmune encephalomyelitis in mice with a disrupted TCR delta chain gene
    • Spahn, T. W., S. Issazadah, A J. Salvin, and H. L. Weiner. 1999. Decreased severity of myelin oligodendrocyte glycoprotein peptide 33-35-induced experimental autoimmune encephalomyelitis in mice with a disrupted TCR delta chain gene. Eur. J. Immunol. 29:4060-4071.
    • (1999) Eur. J. Immunol , vol.29 , pp. 4060-4071
    • Spahn, T.W.1    Issazadah, S.2    Salvin, A.J.3    Weiner, H.L.4
  • 37
    • 0022234330 scopus 로고    scopus 로고
    • Titus, R. G., M. Marchand, T. Boon, and J. A Louis. 1985. A limiting dilution assay for quantifying Leishmania major in tissues of infected mice. Parasite Immunol. 7:545-555.
    • Titus, R. G., M. Marchand, T. Boon, and J. A Louis. 1985. A limiting dilution assay for quantifying Leishmania major in tissues of infected mice. Parasite Immunol. 7:545-555.
  • 39
    • 33947166288 scopus 로고    scopus 로고
    • Cutaneous Leishmania infection: Progress in pathogenesis research and experimental therapy
    • von Stebut, E. 2007. Cutaneous Leishmania infection: progress in pathogenesis research and experimental therapy. Exp. Dermatol. 16:340-346.
    • (2007) Exp. Dermatol , vol.16 , pp. 340-346
    • von Stebut, E.1
  • 40
    • 17644400505 scopus 로고    scopus 로고
    • Network communications: Lymphotoxins, LIGHT, and TNF
    • Ware, C. F. 2005. Network communications: lymphotoxins, LIGHT, and TNF. Annu. Rev. Immunol. 23:787-819.
    • (2005) Annu. Rev. Immunol , vol.23 , pp. 787-819
    • Ware, C.F.1
  • 41
    • 0036319276 scopus 로고    scopus 로고
    • Wilhelm, P., D. S. Riminton, U. Ritter, F. A Umckert, C. Scheidig, R. Hoek, J. D. Sedgwick, and H. Korner. 2002. Membrane lymphotoxin contributes to anti-leishmanial immunity by controlling structural integrity of lymphoid organs. Eur. J. Immunol. 32:1993-2003.
    • Wilhelm, P., D. S. Riminton, U. Ritter, F. A Umckert, C. Scheidig, R. Hoek, J. D. Sedgwick, and H. Korner. 2002. Membrane lymphotoxin contributes to anti-leishmanial immunity by controlling structural integrity of lymphoid organs. Eur. J. Immunol. 32:1993-2003.
  • 42
    • 47249133986 scopus 로고    scopus 로고
    • Lymphotoxin alpha beta 2 (membrane lymphotoxin) is critically important for resistance to Leishmania major infection in mice
    • Xu, G., D. Liu, Y. Fan, X. Yang, H. Korner, Y. X. Fu, and J. E. Uzonna. 2007. Lymphotoxin alpha beta 2 (membrane lymphotoxin) is critically important for resistance to Leishmania major infection in mice. J. Immunol. 179:5358-5366.
    • (2007) J. Immunol , vol.179 , pp. 5358-5366
    • Xu, G.1    Liu, D.2    Fan, Y.3    Yang, X.4    Korner, H.5    Fu, Y.X.6    Uzonna, J.E.7
  • 43
    • 38449084034 scopus 로고    scopus 로고
    • LIGHT Is critical for IL-12 production by dendritic cells, optimal CD4+ Th1 cell response, and resistance to Leishmania major
    • Xu, G., D. Liu, I. Okwor, Y. Wang, H. Korner, S. K. Kung, Y. X. Fu, and J. E. Uzonna. 2007. LIGHT Is critical for IL-12 production by dendritic cells, optimal CD4+ Th1 cell response, and resistance to Leishmania major. J. Immunol. 179:6901-6909.
    • (2007) J. Immunol , vol.179 , pp. 6901-6909
    • Xu, G.1    Liu, D.2    Okwor, I.3    Wang, Y.4    Korner, H.5    Kung, S.K.6    Fu, Y.X.7    Uzonna, J.E.8


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