Ultrasensitive Response Motifs in Biochemical Networks

Quantitative Modeling in Toxicology

Volumn , Issue , 2010, Pages 199-217

  Zhang, Qiang ^a   Bhattacharya, Sudin ^a   Woods, Courtney G ^a   Andersen, Melvin E ^a  

^a HAMNER INSTITUTES FOR HEALTH SCIENCES   (United States)

Author keywords

Combination of motifs six ultrasensitive motifs, in signal transduction and gene networks; Concepts of ultrasensitivity and its relationship to Hill function; Hill function, ultrasensitive response with globally sigmoid shape; Inputs as physiological signals or deleterious environmental perturbations presence sensed through receptor molecules in cell; Positive feedback signaling network motif in biological systems; Transducing signals in ultrasensitive manner being multi faceted; Ultrasensitive motif in biochemical networks and homo multimerization; Ultrasensitive motifs best appreciated in context of protein and gene feedback networks; Ultrasensitive response motifs in biochemical networks

Indexed keywords

EID: 77953992568     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470686263.ch9     Document Type: Chapter

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