-
1
-
-
0034958947
-
Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
-
Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med. 2001;29(7):1303-1310. (Pubitemid 32641789)
-
(2001)
Critical Care Medicine
, vol.29
, Issue.7
, pp. 1303-1310
-
-
Angus, D.C.1
Linde-Zwirble, W.T.2
Lidicker, J.3
Clermont, G.4
Carcillo, J.5
Pinsky, M.R.6
-
3
-
-
41349119386
-
Epigenetic regulation of dendritic cell-derived interleukin-12 facilitates immunosuppression after a severe innate immune response
-
DOI 10.1182/blood-2007-08-106443
-
Wen H, Dou Y, Hogaboam CM, Kunkel SL. Epigenetic regulation of dendritic cell-derived interleukin- 12 facilitates immunosuppression after a severe innate immune response. Blood. 2008; 111(4):1797-1804. (Pubitemid 351451484)
-
(2008)
Blood
, vol.111
, Issue.4
, pp. 1797-1804
-
-
Wen, H.1
Dou, Y.2
Hogaboam, C.M.3
Kunkel, S.L.4
-
4
-
-
0025748883
-
Dysregulation of in vitro cytokine production by monocytes during sepsis
-
Munoz C, Carlet J, Fitting C, Misset B, Bleriot JP, Cavaillon JM. Dysregulation of in vitro cytokine production by monocytes during sepsis. J Clin Invest. 1991;88(5):1747-1754.
-
(1991)
J Clin Invest
, vol.88
, Issue.5
, pp. 1747-1754
-
-
Munoz, C.1
Carlet, J.2
Fitting, C.3
Misset, B.4
Bleriot, J.P.5
Cavaillon, J.M.6
-
5
-
-
36348964853
-
Treatment with GITR agonistic antibody corrects adaptive immune dysfunction in sepsis
-
Scumpia PO, Delano MJ, Kelly-Scumpia KM, et al. Treatment with GITR agonistic antibody corrects adaptive immune dysfunction in sepsis. Blood. 2007;110(10):3673-3681.
-
(2007)
Blood
, vol.110
, Issue.10
, pp. 3673-3681
-
-
Scumpia, P.O.1
Delano, M.J.2
Kelly-Scumpia, K.M.3
-
6
-
-
33751576739
-
Increased natural CD4+CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis
-
Scumpia PO, Delano MJ, Kelly KM, et al. Increased natural CD4+CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis. J Immunol. 2006;177(11):7943-7949.
-
(2006)
J Immunol
, vol.177
, Issue.11
, pp. 7943-7949
-
-
Scumpia, P.O.1
Delano, M.J.2
Kelly, K.M.3
-
7
-
-
43349107987
-
Regulatory T cell populations in sepsis and trauma
-
DOI 10.1189/jlb.0607371
-
Venet F, Chung CS, Monneret G, et al. Regulatory T cell populations in sepsis and trauma. J Leukoc Biol. 2008;83(3):523-535. (Pubitemid 351966861)
-
(2008)
Journal of Leukocyte Biology
, vol.83
, Issue.3
, pp. 523-535
-
-
Venet, F.1
Chung, C.-S.2
Monneret, G.3
Huang, X.4
Horner, B.5
Garber, M.6
Ayala, A.7
-
8
-
-
15244354286
-
Regulatory T cell lineage specification by the forkhead transcription factor foxp3
-
Fontenot JD, Rasmussen JP, Williams LM, Dooley JL, Farr AG, Rudensky AY. Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity. 2005;22(3):329-341.
-
(2005)
Immunity
, vol.22
, Issue.3
, pp. 329-341
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Williams, L.M.3
Dooley, J.L.4
Farr, A.G.5
Rudensky, A.Y.6
-
9
-
-
33847337912
-
Tumor evasion of the immune system by converting CD4+CD25- T cells into CD4+CD25+ T regulatory cells: Role of tumor-derived TGF-beta
-
Liu VC, Wong LY, Jang T, et al. Tumor evasion of the immune system by converting CD4+CD25- T cells into CD4+CD25+ T regulatory cells: role of tumor-derived TGF-beta. J Immunol. 2007; 178(5):2883-2892.
-
(2007)
J Immunol
, vol.178
, Issue.5
, pp. 2883-2892
-
-
Liu, V.C.1
Wong, L.Y.2
Jang, T.3
-
10
-
-
34547757390
-
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid
-
Sun CM, Hall JA, Blank RB, et al. Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J Exp Med. 2007;204(8):1775-1785.
-
(2007)
J Exp Med
, vol.204
, Issue.8
, pp. 1775-1785
-
-
Sun, C.M.1
Hall, J.A.2
Blank, R.B.3
-
11
-
-
47249134183
-
Plasticity of regulatory T cells: Subversion of suppressive function and conversion to enhancement of lung allergic responses
-
Joetham A, Matsubara S, Okamoto M, et al. Plasticity of regulatory T cells: subversion of suppressive function and conversion to enhancement of lung allergic responses. J Immunol. 2008; 180(11):7117-7124.
-
(2008)
J Immunol
, vol.180
, Issue.11
, pp. 7117-7124
-
-
Joetham, A.1
Matsubara, S.2
Okamoto, M.3
-
12
-
-
64149088746
-
Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity
-
Manicassamy S, Ravindran R, Deng J, et al. Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity. Nat Med. 2009;15(4):401-409.
-
(2009)
Nat Med
, vol.15
, Issue.4
, pp. 401-409
-
-
Manicassamy, S.1
Ravindran, R.2
Deng, J.3
-
13
-
-
58849118836
-
Epigenetic control of FOXP3 expression: The key to a stable regulatory T-cell lineage?
-
Huehn J, Polansky JK, Hamann A. Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage? Nat Rev Immunol. 2009;9(2):83-89.
-
(2009)
Nat Rev Immunol
, vol.9
, Issue.2
, pp. 83-89
-
-
Huehn, J.1
Polansky, J.K.2
Hamann, A.3
-
14
-
-
33644844341
-
Molecular mechanisms underlying FOXP3 induction in human T cells
-
Mantel PY, Ouaked N, Ruckert B, et al. Molecular mechanisms underlying FOXP3 induction in human T cells. J Immunol. 2006;176(6):3593-3602. (Pubitemid 43364007)
-
(2006)
Journal of Immunology
, vol.176
, Issue.6
, pp. 3593-3602
-
-
Mantel, P.-Y.1
Ouaked, N.2
Ruckert, B.3
Karagiannidis, C.4
Welz, R.5
Blaser, K.6
Schmidt-Weber, C.B.7
-
15
-
-
34447265236
-
CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: A role for DNA methylation
-
DOI 10.1084/jem.20070109
-
Kim HP, Leonard WJ. CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNAmethylation. J Exp Med. 2007;204(7):1543-1551. (Pubitemid 47048022)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.7
, pp. 1543-1551
-
-
Kim, H.-P.1
Leonard, W.J.2
-
16
-
-
18244376372
-
Reversal of long-term sepsis-induced immunosuppression by dendritic cells
-
Benjamim CF, Lundy SK, Lukacs NW, Hogaboam CM, Kunkel SL. Reversal of long-term sepsis-induced immunosuppression by dendritic cells. Blood. 2005;105(9):3588-3595.
-
(2005)
Blood
, vol.105
, Issue.9
, pp. 3588-3595
-
-
Benjamim, C.F.1
Lundy, S.K.2
Lukacs, N.W.3
Hogaboam, C.M.4
Kunkel, S.L.5
-
17
-
-
0029693826
-
Basic DNA and RNA protocols. Introduction
-
Harwood AJ. Basic DNA and RNA protocols. Introduction. Methods Mol Biol. 1996;58:v-vi.
-
(1996)
Methods Mol Biol
, vol.58
-
-
Harwood, A.J.1
-
18
-
-
33846980131
-
Epigenetic control of the foxp3 locus in regulatory T cells
-
Floess S, Freyer J, Siewert C, et al. Epigenetic control of the foxp3 locus in regulatory T cells. PLoS Biol. 2007;5(2):e38.
-
(2007)
PLoS Biol
, vol.5
, Issue.2
-
-
Floess, S.1
Freyer, J.2
Siewert, C.3
-
19
-
-
53349164200
-
Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responses
-
Hall JA, Bouladoux N, Sun CM, et al. Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responses. Immunity. 2008;29(4):637-649.
-
(2008)
Immunity
, vol.29
, Issue.4
, pp. 637-649
-
-
Hall, J.A.1
Bouladoux, N.2
Sun, C.M.3
-
20
-
-
0029131403
-
Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells
-
Wang J, Sun L, Myeroff L, et al. Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells. J Biol Chem. 1995;270(37):22044-22049.
-
(1995)
J Biol Chem
, vol.270
, Issue.37
, pp. 22044-22049
-
-
Wang, J.1
Sun, L.2
Myeroff, L.3
-
21
-
-
33750288937
-
Apoptosis and caspases regulate death and inflammation in sepsis
-
Hotchkiss RS, Nicholson DW. Apoptosis and caspases regulate death and inflammation in sepsis. Nat Rev Immunol. 2006;6(11):813-822.
-
(2006)
Nat Rev Immunol
, vol.6
, Issue.11
, pp. 813-822
-
-
Hotchkiss, R.S.1
Nicholson, D.W.2
-
22
-
-
0035338993
-
Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans
-
Hotchkiss RS, Tinsley KW, Swanson PE, et al. Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans. J Immunol. 2001;166(11):6952-6963.
-
(2001)
J Immunol
, vol.166
, Issue.11
, pp. 6952-6963
-
-
Hotchkiss, R.S.1
Tinsley, K.W.2
Swanson, P.E.3
-
23
-
-
33846016948
-
Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation
-
DOI 10.1074/jbc.M608848200
-
Chen C, Rowell EA, Thomas RM, Hancock WW, Wells AD. Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation. J Biol Chem. 2006;281(48):36828-36834. (Pubitemid 46042151)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.48
, pp. 36828-36834
-
-
Chen, C.1
Rowell, E.A.2
Thomas, R.M.3
Hancock, W.W.4
Wells, A.D.5
-
24
-
-
0036195161
-
CD4(+)CD25(+) immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
-
McHugh RS, Whitters MJ, Piccirillo CA, et al. CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity. 2002;16(2):311-323.
-
(2002)
Immunity
, vol.16
, Issue.2
, pp. 311-323
-
-
McHugh, R.S.1
Whitters, M.J.2
Piccirillo, C.A.3
-
25
-
-
17844364002
-
A role for CD103 in the retention of CD4+CD25+ Treg and control of Leishmania major infection
-
Suffia I, Reckling SK, Salay G, Belkaid Y. A role for CD103 in the retention of CD4+CD25+ Treg and control of Leishmania major infection. J Immunol. 2005;174(9):5444-5455.
-
(2005)
J Immunol
, vol.174
, Issue.9
, pp. 5444-5455
-
-
Suffia, I.1
Reckling, S.K.2
Salay, G.3
Belkaid, Y.4
-
26
-
-
0035839136
-
Translating the histone code
-
Jenuwein T, Allis CD. Translating the histone code. Science. 2001;293(5532):1074-1080.
-
(2001)
Science
, vol.293
, Issue.5532
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
27
-
-
0031821875
-
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
Thornton AM, Shevach EM. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med. 1998;188(2):287-296.
-
(1998)
J Exp Med
, vol.188
, Issue.2
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
28
-
-
36749007248
-
+ regulatory T cells
-
DOI 10.1073/pnas.0703642104
-
Wei J, Duramad O, Perng OA, Reiner SL, Liu YJ, Qin FX. Antagonistic nature of T helper 1/2 developmental programs in opposing peripheral induction of Foxp3+ regulatory T cells. Proc Natl Acad Sci U S A. 2007;104(46):18169- 18174. (Pubitemid 350210839)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.46
, pp. 18169-18174
-
-
Wei, J.1
Duramad, O.2
Perng, O.A.3
Reiner, S.L.4
Liu, Y.-J.5
Qin, F.X.-F.6
-
29
-
-
0035172366
-
Sepsis-induced immunosuppression: From bad to worse
-
Reddy RC, Chen GH, Tekchandani PK, Standiford TJ. Sepsis-induced immunosuppression: from bad to worse. Immunol Res. 2001;24(3):273-287.
-
(2001)
Immunol Res
, vol.24
, Issue.3
, pp. 273-287
-
-
Reddy, R.C.1
Chen, G.H.2
Tekchandani, P.K.3
Standiford, T.J.4
-
30
-
-
0036336711
-
Clinical review: Immunodepression in the surgical patient and increased susceptibility to infection
-
Angele MK, Faist E. Clinical review: immunodepression in the surgical patient and increased susceptibility to infection. Crit Care. 2002;6(4):298-305. (Pubitemid 34863695)
-
(2002)
Critical Care
, vol.6
, Issue.4
, pp. 298-305
-
-
Angele, M.K.1
Faist, E.2
-
32
-
-
0030915659
-
Chronic allograft failure: The clinical problem
-
Nagano H, Tilney NL. Chronic allograft failure: the clinical problem. Am J Med Sci. 1997;313(5):305-309.
-
(1997)
Am J Med Sci
, vol.313
, Issue.5
, pp. 305-309
-
-
Nagano, H.1
Tilney, N.L.2
-
33
-
-
0037108502
-
An increase in the susceptibility of burned patients to infectious complications due to impaired production of macrophage inflammatory protein 1 alpha
-
Kobayashi M, Takahashi H, Sanford AP, Herndon DN, Pollard RB, Suzuki F. An increase in the susceptibility of burned patients to infectious complications due to impaired production of macrophage inflammatory protein 1 alpha. J Immunol. 2002;169(8):4460-4466.
-
(2002)
J Immunol
, vol.169
, Issue.8
, pp. 4460-4466
-
-
Kobayashi, M.1
Takahashi, H.2
Sanford, A.P.3
Herndon, D.N.4
Pollard, R.B.5
Suzuki, F.6
-
34
-
-
33847011663
-
The contribution of CD4+ CD25+ T-regulatory- cells to immune suppression in sepsis
-
Wisnoski N, Chung CS, Chen Y, Huang X, Ayala A. The contribution of CD4+ CD25+ T-regulatory- cells to immune suppression in sepsis. Shock. 2007;27(3):251-257.
-
(2007)
Shock
, vol.27
, Issue.3
, pp. 251-257
-
-
Wisnoski, N.1
Chung, C.S.2
Chen, Y.3
Huang, X.4
Ayala, A.5
-
35
-
-
34250864955
-
Interaction of TNF with TNF receptor type 2 promotes expansion and function of mouse CD4+CD25+ T regulatory cells
-
Chen X, Baumel M, Mannel DN, Howard OM, Oppenheim JJ. Interaction of TNF with TNF receptor type 2 promotes expansion and function of mouse CD4+CD25+ T regulatory cells. J Immunol. 2007;179(1):154-161.
-
(2007)
J Immunol
, vol.179
, Issue.1
, pp. 154-161
-
-
Chen, X.1
Baumel, M.2
Mannel, D.N.3
Howard, O.M.4
Oppenheim, J.J.5
-
36
-
-
18944371642
-
Adoptive transfer of in vitro-stimulated CD4+CD25+ regulatory T cells increases bacterial clearance and improves survival in polymicrobial sepsis
-
Heuer JG, Zhang T, Zhao J, et al. Adoptive transfer of in vitro-stimulated CD4+CD25+ regulatory T cells increases bacterial clearance and improves survival in polymicrobial sepsis. J Immunol. 2005;174(11):7141-7146.
-
(2005)
J Immunol
, vol.174
, Issue.11
, pp. 7141-7146
-
-
Heuer, J.G.1
Zhang, T.2
Zhao, J.3
-
37
-
-
0345275927
-
Septic mice are susceptible to pulmonary aspergillosis
-
Benjamim CF, Hogaboam CM, Lukacs NW, Kunkel SL. Septic mice are susceptible to pulmonary aspergillosis. Am J Pathol. 2003;163(6):2605-2617.
-
(2003)
Am J Pathol
, vol.163
, Issue.6
, pp. 2605-2617
-
-
Benjamim, C.F.1
Hogaboam, C.M.2
Lukacs, N.W.3
Kunkel, S.L.4
-
38
-
-
33847125247
-
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
-
Wan YY, Flavell RA. Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression. Nature. 2007;445(7129):766-770.
-
(2007)
Nature
, vol.445
, Issue.7129
, pp. 766-770
-
-
Wan, Y.Y.1
Flavell, R.A.2
-
39
-
-
0348223787
-
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
-
Chen W, Jin W, Hardegen N, et al. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med. 2003;198(12):1875-1886.
-
(2003)
J Exp Med
, vol.198
, Issue.12
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
-
40
-
-
34547699396
-
Type II monocytes modulate T cell-mediated central nervous system autoimmune disease
-
Weber MS, Prod'homme T, Youssef S, et al. Type II monocytes modulate T cell-mediated central nervous system autoimmune disease. Nat Med. 2007;13(8):935-943.
-
(2007)
Nat Med
, vol.13
, Issue.8
, pp. 935-943
-
-
Weber, M.S.1
Prod'homme, T.2
Youssef, S.3
-
41
-
-
0032933560
-
IL-10 is a major mediator of sepsis-induced impairment in lung antibacterial host defense
-
Steinhauser ML, Hogaboam CM, Kunkel SL, Lukacs NW, Strieter RM, Standiford TJ. IL-10 is a major mediator of sepsis-induced impairment in lung antibacterial host defense. J Immunol. 1999;162(1):392-399.
-
(1999)
J Immunol
, vol.162
, Issue.1
, pp. 392-399
-
-
Steinhauser, M.L.1
Hogaboam, C.M.2
Kunkel, S.L.3
Lukacs, N.W.4
Strieter, R.M.5
Standiford, T.J.6
-
42
-
-
32244442562
-
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity. 2006;24(2):179-189.
-
(2006)
Immunity
, vol.24
, Issue.2
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
-
44
-
-
34547657483
-
Incidence of malignancies in heart and/or lung transplant recipients: A single-institution experience
-
Roithmaier S, Haydon AM, Loi S, et al. Incidence of malignancies in heart and/or lung transplant recipients: a single-institution experience. J Heart Lung Transplant. 2007;26(8):845-849.
-
(2007)
J Heart Lung Transplant
, vol.26
, Issue.8
, pp. 845-849
-
-
Roithmaier, S.1
Haydon, A.M.2
Loi, S.3
-
45
-
-
31644432589
-
Regulatory T cells in immune surveillance and treatment of cancer
-
Yamaguchi T, Sakaguchi S. Regulatory T cells in immune surveillance and treatment of cancer. Semin Cancer Biol. 2006;16(2):115-123.
-
(2006)
Semin Cancer Biol
, vol.16
, Issue.2
, pp. 115-123
-
-
Yamaguchi, T.1
Sakaguchi, S.2
-
46
-
-
0031939403
-
CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells
-
Suri-Payer E, Amar AZ, Thornton AM, Shevach EM. CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells. J Immunol. 1998;160(3):1212-1218.
-
(1998)
J Immunol
, vol.160
, Issue.3
, pp. 1212-1218
-
-
Suri-Payer, E.1
Amar, A.Z.2
Thornton, A.M.3
Shevach, E.M.4
-
47
-
-
12244285937
-
Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo
-
Chen ML, Pittet MJ, Gorelik L, et al. Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo. Proc Natl Acad Sci U S A. 2005;102(2):419-424.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.2
, pp. 419-424
-
-
Chen, M.L.1
Pittet, M.J.2
Gorelik, L.3
-
48
-
-
67349162130
-
Tumour necrosis factor and cancer
-
Balkwill F. Tumour necrosis factor and cancer. Nat Rev Cancer. 2009;9(5):361-371.
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.5
, pp. 361-371
-
-
Balkwill, F.1
-
49
-
-
37549021446
-
Therapy-induced antitumor vaccination by targeting tumor necrosis factor alpha to tumor vessels in combination with melphalan
-
Mortara L, Balza E, Sassi F, et al. Therapy-induced antitumor vaccination by targeting tumor necrosis factor alpha to tumor vessels in combination with melphalan. Eur J Immunol. 2007;37(12):3381-3392.
-
(2007)
Eur J Immunol
, vol.37
, Issue.12
, pp. 3381-3392
-
-
Mortara, L.1
Balza, E.2
Sassi, F.3
|