-
1
-
-
15244340251
-
TGFbeta1, back to the future: revisiting its role as a transforming growth factor
-
Glick, A.B. (2004) TGFbeta1, back to the future: revisiting its role as a transforming growth factor. Cancer Biol. Ther., 3, 276-283.
-
(2004)
Cancer Biol. Ther.
, vol.3
, pp. 276-283
-
-
Glick, A.B.1
-
2
-
-
0030598681
-
TGFβ1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice
-
Cui, W. et al. (1996) TGFβ1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice. Cell, 86, 531-542.
-
(1996)
Cell
, vol.86
, pp. 531-542
-
-
Cui, W.1
-
3
-
-
0035887461
-
Inducible expression of transforming growth factor beta1 in papillomas causes rapid metastasis
-
Weeks, B.H. et al. (2001) Inducible expression of transforming growth factor beta1 in papillomas causes rapid metastasis. Cancer Res., 61, 7435-7443.
-
(2001)
Cancer Res.
, vol.61
, pp. 7435-7443
-
-
Weeks, B.H.1
-
4
-
-
33645988531
-
Inflammation in epithelial skin tumours: old stories and new ideas
-
Mueller, M.M. (2006) Inflammation in epithelial skin tumours: old stories and new ideas. Eur. J. Cancer, 42, 735-744.
-
(2006)
Eur. J. Cancer
, vol.42
, pp. 735-744
-
-
Mueller, M.M.1
-
5
-
-
0023874730
-
Localized production of TGF-beta mRNA in tumour promoter-stimulated mouse epidermis
-
Akhurst, R.J. et al. (1988) Localized production of TGF-beta mRNA in tumour promoter-stimulated mouse epidermis. Nature, 331, 363-365.
-
(1988)
Nature
, vol.331
, pp. 363-365
-
-
Akhurst, R.J.1
-
6
-
-
2642614530
-
Transforming growth factor-β is a new form of tumor suppressor with true haploid insufficiency
-
Tang, B. et al. (1998) Transforming growth factor-β is a new form of tumor suppressor with true haploid insufficiency. Nat. Med., 4, 802-807.
-
(1998)
Nat. Med.
, vol.4
, pp. 802-807
-
-
Tang, B.1
-
7
-
-
7444272649
-
Smad3 knockout mice exhibit a resistance to skin chemical carcinogenesis
-
Li, A.G. et al. (2004) Smad3 knockout mice exhibit a resistance to skin chemical carcinogenesis. Cancer Res., 64, 7836-7845.
-
(2004)
Cancer Res.
, vol.64
, pp. 7836-7845
-
-
Li, A.G.1
-
8
-
-
0027531528
-
Transforming growth factor-β1 null mutation in mice causes excessive inflammatory response and early death
-
Kulkarni, A.B. et al. (1992) Transforming growth factor-β1 null mutation in mice causes excessive inflammatory response and early death. Proc. Natl Acad. Sci. USA, 90, 770-774.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 770-774
-
-
Kulkarni, A.B.1
-
9
-
-
0035979272
-
Conditional epidermal expression of TGFbeta 1 blocks neonatal lethality but causes a reversible hyperplasia and alopecia
-
Liu, X. et al. (2001) Conditional epidermal expression of TGFbeta 1 blocks neonatal lethality but causes a reversible hyperplasia and alopecia. Proc. Natl Acad. Sci. USA, 98, 9139-9144.
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 9139-9144
-
-
Liu, X.1
-
10
-
-
33847185965
-
Localization of TGF-beta signaling intermediates Smad2 3 4 and 7 in developing and mature human and mouse kidney
-
Banas, M.C. et al. (2007) Localization of TGF-beta signaling intermediates Smad2, 3, 4, and 7 in developing and mature human and mouse kidney. J. Histochem. Cytochem., 55, 275-285.
-
(2007)
J. Histochem. Cytochem.
, vol.55
, pp. 275-285
-
-
Banas, M.C.1
-
11
-
-
33847655732
-
The contribution of bone marrow-derived cells to the development of renal interstitial fibrosis
-
Li, J. et al. (2007) The contribution of bone marrow-derived cells to the development of renal interstitial fibrosis. Stem Cells, 25, 697-706.
-
(2007)
Stem Cells
, vol.25
, pp. 697-706
-
-
Li, J.1
-
12
-
-
34147136520
-
Dynamic stromal-epithelial interactions during progression of MCF10DCIS.com xenografts
-
Tait, L.R. et al. (2007) Dynamic stromal-epithelial interactions during progression of MCF10DCIS.com xenografts. Int. J. Cancer, 120, 2127-2134.
-
(2007)
Int. J. Cancer
, vol.120
, pp. 2127-2134
-
-
Tait, L.R.1
-
13
-
-
0028171401
-
Targeted deletion of the TGF-beta 1 gene causes rapid progression to squamous cell carcinoma
-
Glick, A.B. et al. (1994) Targeted deletion of the TGF-beta 1 gene causes rapid progression to squamous cell carcinoma. Genes Dev., 8, 2429-2440.
-
(1994)
Genes Dev.
, vol.8
, pp. 2429-2440
-
-
Glick, A.B.1
-
14
-
-
0023876867
-
Comparison of protein kinase C functional assays to clarify mechanisms of inhibitor action
-
Nakadate, T. et al. (1988) Comparison of protein kinase C functional assays to clarify mechanisms of inhibitor action. Biochem. Pharmacol., 37, 15411545.
-
(1988)
Biochem. Pharmacol.
, vol.37
, pp. 1541-1545
-
-
Nakadate, T.1
-
15
-
-
0017370855
-
The cornified envelope of terminally differentiated human epidermal keratinocytes consists of cross-linked protein
-
Rice, R.H. et al. (1977) The cornified envelope of terminally differentiated human epidermal keratinocytes consists of cross-linked protein. Cell, 11, 417-422.
-
(1977)
Cell
, vol.11
, pp. 417-422
-
-
Rice, R.H.1
-
16
-
-
0033990048
-
Primer3 on the WWW for general users and for biologist programmers
-
Rozen, S. et al. (2000) Primer3 on the WWW for general users and for biologist programmers. Methods Mol. Biol., 132, 365-386.
-
(2000)
Methods Mol. Biol.
, vol.132
, pp. 365-386
-
-
Rozen, S.1
-
17
-
-
0029073142
-
Transforming growth factor β induces the cyclindependent kinase inhibitor p21 through a p53-independent mechanism
-
Datto, M.B. et al. (1995) Transforming growth factor β induces the cyclindependent kinase inhibitor p21 through a p53-independent mechanism. Proc. Natl Acad. Sci. USA, 92, 5545-5549.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 5545-5549
-
-
Datto, M.B.1
-
18
-
-
0028339689
-
Altered expression of transforming growth factor-beta 1 mRNA and protein in mouse skin carcinogenesis
-
Patamalai, B. et al. (1994) Altered expression of transforming growth factor-beta 1 mRNA and protein in mouse skin carcinogenesis. Mol. Carcinog., 9, 220-229.
-
(1994)
Mol. Carcinog.
, vol.9
, pp. 220-229
-
-
Patamalai, B.1
-
19
-
-
0027439204
-
Transforming growth factor β1 induction is associated with transforming growth factors β2 and β3 down-modulation in 12O-tetradecanoylphorbol-13-acetate-induced skin hyperplasia
-
Escherick, J.S. et al. (1993) Transforming growth factor β1 induction is associated with transforming growth factors β2 and β3 down-modulation in 12O-tetradecanoylphorbol-13-acetate-induced skin hyperplasia. Cancer Res., 53, 5517-5522.
-
(1993)
Cancer Res.
, vol.53
, pp. 5517-5522
-
-
Escherick, J.S.1
-
20
-
-
0032104245
-
The extended protein kinase C superfamily
-
Mellor, H. et al. (1998) The extended protein kinase C superfamily. Biochem. J., 332, 281-292.
-
(1998)
Biochem. J.
, vol.332
, pp. 281-292
-
-
Mellor, H.1
-
21
-
-
0024848815
-
Activation of the second promoter of the transforming growth factor-beta 1 gene by transforming growth factor-beta 1 and phorbol ester occurs through the same target sequences
-
Kim, S.J. et al. (1989) Activation of the second promoter of the transforming growth factor-beta 1 gene by transforming growth factor-beta 1 and phorbol ester occurs through the same target sequences. J. Biol. Chem., 264, 19373-19378.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 19373-19378
-
-
Kim, S.J.1
-
22
-
-
0034643258
-
Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis
-
Tsubouchi, Y. et al. (2000) Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis. Biochem. Biophys. Res. Commun., 270, 400-405.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.270
, pp. 400-405
-
-
Tsubouchi, Y.1
-
23
-
-
0020035562
-
The tumor promoter, 12-O-tetradecanoylphorbol-13-acetate accelerates keratinocyte differentiation and stimulates growth of an unidentified cell type in cultured human epidermis
-
Hawley-Nelson, P. et al. (1982) The tumor promoter, 12-O-tetradecanoylphorbol-13-acetate accelerates keratinocyte differentiation and stimulates growth of an unidentified cell type in cultured human epidermis. Exp. Cell Res., 137, 155-167.
-
(1982)
Exp. Cell Res.
, vol.137
, pp. 155-167
-
-
Hawley-Nelson, P.1
-
24
-
-
0020080466
-
Divergent responses in epidermal basal cells exposed to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate
-
Yuspa, S.H. et al. (1982) Divergent responses in epidermal basal cells exposed to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate. Cancer Res., 42, 2344-2349.
-
(1982)
Cancer Res.
, vol.42
, pp. 2344-2349
-
-
Yuspa, S.H.1
-
25
-
-
0037443667
-
Proinflammatory activities of S100: proteins S100A8, S100A9, and S100A8/A9 induce neutrophil chemotaxis and adhesion
-
Ryckman, C. et al. (2003) Proinflammatory activities of S100: proteins S100A8, S100A9, and S100A8/A9 induce neutrophil chemotaxis and adhesion. J. Immunol., 170, 3233-3242.
-
(2003)
J. Immunol.
, vol.170
, pp. 3233-3242
-
-
Ryckman, C.1
-
26
-
-
0031253960
-
Chemokine networks in vivo: involvement of C-XC and C-C chemokines in neutrophil extravasation in vivo in response to TNF-alpha
-
Tessier, P.A. et al. (1997) Chemokine networks in vivo: involvement of C-XC and C-C chemokines in neutrophil extravasation in vivo in response to TNF-alpha. J. Immunol., 159, 3595-3602.
-
(1997)
J. Immunol.
, vol.159
, pp. 3595-3602
-
-
Tessier, P.A.1
-
27
-
-
0033590207
-
The role of cyclooxygenases in inflammation, cancer, and development
-
Williams, C.S. et al. (1999) The role of cyclooxygenases in inflammation, cancer, and development. Oncogene, 18, 7908-7916.
-
(1999)
Oncogene
, vol.18
, pp. 7908-7916
-
-
Williams, C.S.1
-
28
-
-
0021141757
-
Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas
-
Balmain, A. et al. (1984) Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas. Nature, 307, 658-660.
-
(1984)
Nature
, vol.307
, pp. 658-660
-
-
Balmain, A.1
-
29
-
-
0023522394
-
Ha oncogene and its p21 product in chemically induced skin tumors and tumor-derived cell lines
-
Ha oncogene and its p21 product in chemically induced skin tumors and tumor-derived cell lines. Carcinogenesis, 8, 1821-1825.
-
(1987)
Carcinogenesis
, vol.8
, pp. 1821-1825
-
-
Harper, J.R.1
-
30
-
-
0028609621
-
Alterations in murine keratinocyte differentiation induced by activated rasHa genes are mediated by protein kinase C-alpha
-
Dlugosz, A.A. et al. (1994) Alterations in murine keratinocyte differentiation induced by activated rasHa genes are mediated by protein kinase C-alpha. Cancer Res., 54, 6413-6420.
-
(1994)
Cancer Res.
, vol.54
, pp. 6413-6420
-
-
Dlugosz, A.A.1
-
31
-
-
0022977903
-
An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue
-
Roop, D.R. et al. (1986) An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue. Nature, 323, 822-824.
-
(1986)
Nature
, vol.323
, pp. 822-824
-
-
Roop, D.R.1
-
32
-
-
0023234750
-
Early inflammatory changes in the skin of SENCAR and C57BL/6 mice following exposure to 12-O-tetradecanoylphorbol13-acetate
-
Lewis, J.G. et al. (1987) Early inflammatory changes in the skin of SENCAR and C57BL/6 mice following exposure to 12-O-tetradecanoylphorbol13-acetate. Carcinogenesis, 8, 889-898.
-
(1987)
Carcinogenesis
, vol.8
, pp. 889-898
-
-
Lewis, J.G.1
-
33
-
-
0033564547
-
Blocking transforming growth factor β signaling in transgenic epidermis accelerates chemical carcinogenesis: a mechanism associated with increased angiogenesis
-
Go, C. et al. (1999) Blocking transforming growth factor β signaling in transgenic epidermis accelerates chemical carcinogenesis: a mechanism associated with increased angiogenesis. Cancer Res., 59, 2861-2868.
-
(1999)
Cancer Res.
, vol.59
, pp. 2861-2868
-
-
Go, C.1
-
34
-
-
0028990043
-
Chemical skin carcinogenesis is prevented in mice by the induced expression of a TGF-β related transgene
-
Blessing, M. et al. (1995) Chemical skin carcinogenesis is prevented in mice by the induced expression of a TGF-β related transgene. Teratog. Carcinog. Mutagen., 15, 11-21.
-
(1995)
Teratog. Carcinog. Mutagen.
, vol.15
, pp. 11-21
-
-
Blessing, M.1
-
35
-
-
36849069894
-
Protein kinase C family: on the crossroads of cell signaling in skin and tumor epithelium
-
Breitkreutz, D. et al. (2007) Protein kinase C family: on the crossroads of cell signaling in skin and tumor epithelium. J. Cancer Res. Clin. Oncol., 133, 793-808.
-
(2007)
J. Cancer Res. Clin. Oncol.
, vol.133
, pp. 793-808
-
-
Breitkreutz, D.1
-
36
-
-
1642303050
-
Expressions of inhibitory Smads, Smad6 and Smad7, are differentially regulated by TPA in human lung fibroblast cells
-
Tsunobuchi, H. et al. (2004) Expressions of inhibitory Smads, Smad6 and Smad7, are differentially regulated by TPA in human lung fibroblast cells. Biochem. Biophys. Res. Commun., 316, 712-719.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.316
, pp. 712-719
-
-
Tsunobuchi, H.1
-
37
-
-
0041883785
-
Smad3 and PKCdelta mediate TGF-beta1induced collagen I expression in human mesangial cells
-
Runyan, C.E. et al. (2003) Smad3 and PKCdelta mediate TGF-beta1induced collagen I expression in human mesangial cells. Am. J. Physiol. Renal Physiol., 285, F413-F422.
-
(2003)
Am. J. Physiol. Renal Physiol.
, vol.285
-
-
Runyan, C.E.1
-
38
-
-
34347373902
-
TGF-beta1 induction of p21WAF1/cip1 requires smadindependent protein kinase C signaling pathway
-
Kim, Y.K. (2007) TGF-beta1 induction of p21WAF1/cip1 requires smadindependent protein kinase C signaling pathway. Arch. Pharm. Res., 30, 739-742.
-
(2007)
Arch. Pharm. Res.
, vol.30
, pp. 739-742
-
-
Kim, Y.K.1
-
39
-
-
42049109067
-
TGF-beta mediates PTEN suppression and cell motility through calcium-dependent PKC-alpha activation in pancreatic cancer cells
-
Chow, J.Y. et al. (2008) TGF-beta mediates PTEN suppression and cell motility through calcium-dependent PKC-alpha activation in pancreatic cancer cells. Am. J. Physiol. Gastrointest. Liver Physiol., 294, G899-G905.
-
(2008)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.294
-
-
Chow, J.Y.1
-
40
-
-
0029946961
-
Differentiation of mouse keratinocytes is accompanied by PKC-dependent changes in AP-1 proteins
-
Rutberg, S.E. et al. (1996) Differentiation of mouse keratinocytes is accompanied by PKC-dependent changes in AP-1 proteins. Oncogene, 13, 167176.
-
(1996)
Oncogene
, vol.13
, pp. 167-176
-
-
Rutberg, S.E.1
-
41
-
-
0030883604
-
Opposing activities of c-Fos and Fra-2 on AP-1 regulated transcriptional activity in mouse keratinocytes induced to differentiate by calcium and phorbol esters
-
Rutberg, S.E. et al. (1997) Opposing activities of c-Fos and Fra-2 on AP-1 regulated transcriptional activity in mouse keratinocytes induced to differentiate by calcium and phorbol esters. Oncogene, 15, 1337-1346.
-
(1997)
Oncogene
, vol.15
, pp. 1337-1346
-
-
Rutberg, S.E.1
-
42
-
-
38849207688
-
Context dependent regulation of cutaneous immunological responses by TGF{beta}1 and its role in skin carcinogenesis
-
Glick, A. et al. (2007) Context dependent regulation of cutaneous immunological responses by TGF{beta}1 and its role in skin carcinogenesis. Carcinogenesis, 29, 9-14.
-
(2007)
Carcinogenesis
, vol.29
, pp. 9-14
-
-
Glick, A.1
-
43
-
-
0037142609
-
Calgranulins S100A8 and S100A9 are negatively regulated by glucocorticoids in a c-Fos-dependent manner and overexpressed throughout skin carcinogenesis
-
Gebhardt, C. et al. (2002) Calgranulins S100A8 and S100A9 are negatively regulated by glucocorticoids in a c-Fos-dependent manner and overexpressed throughout skin carcinogenesis. Oncogene, 21, 4266-4276.
-
(2002)
Oncogene
, vol.21
, pp. 4266-4276
-
-
Gebhardt, C.1
-
44
-
-
0033195998
-
Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response [see comments]
-
Ashcroft, G.S. et al. (1999) Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response [see comments]. Nat. Cell Biol., 1, 260-266.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 260-266
-
-
Ashcroft, G.S.1
-
45
-
-
0028330331
-
Neutrophil chemotaxis in response to TGF-beta isoforms (TGF-beta 1, TGF-beta 2, TGF-beta 3) is mediated by fibronectin 20
-
Parekh, T. et al. (1994) Neutrophil chemotaxis in response to TGF-beta isoforms (TGF-beta 1, TGF-beta 2, TGF-beta 3) is mediated by fibronectin 20. J. Immunol., 152, 2456-2466.
-
(1994)
J. Immunol.
, vol.152
, pp. 2456-2466
-
-
Parekh, T.1
-
46
-
-
34547863906
-
The high-risk benign tumor: evidence from the twostage skin cancer model and relevance for human cancer
-
Glick, A. et al. (2007) The high-risk benign tumor: evidence from the twostage skin cancer model and relevance for human cancer. Mol. Carcinog., 46, 605-610.
-
(2007)
Mol. Carcinog.
, vol.46
, pp. 605-610
-
-
Glick, A.1
-
47
-
-
0033593025
-
Defects in transforming growth factor-β signaling cooperate with a ras oncogene to cause rapid aneuploidy and malignant transformation of mouse keratinocytes
-
Glick, A. et al. (1999) Defects in transforming growth factor-β signaling cooperate with a ras oncogene to cause rapid aneuploidy and malignant transformation of mouse keratinocytes. Proc. Natl Acad. Sci. USA, 96, 14949-14954.
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 14949-14954
-
-
Glick, A.1
-
48
-
-
34547878575
-
Expression profile of skin papillomas with high cancer risk displays a unique genetic signature that clusters with squamous cell carcinomas and predicts risk for malignant conversion
-
Darwiche, N. et al. (2007) Expression profile of skin papillomas with high cancer risk displays a unique genetic signature that clusters with squamous cell carcinomas and predicts risk for malignant conversion. Oncogene, 26, 6885-6895.
-
(2007)
Oncogene
, vol.26
, pp. 6885-6895
-
-
Darwiche, N.1
-
49
-
-
0029784067
-
Transforming growth factor-β1 suppresses genomic instability independent of a G1 arrest, p53 and Rb
-
Glick, A.B. et al. (1996) Transforming growth factor-β1 suppresses genomic instability independent of a G1 arrest, p53 and Rb. Cancer Res., 56, 3645-3650.
-
(1996)
Cancer Res.
, vol.56
, pp. 3645-3650
-
-
Glick, A.B.1
-
50
-
-
33845303212
-
Inhibition of transforming growth factor-beta1 signaling attenuates ataxia telangiectasia mutated activity in response to genotoxic stress
-
Kirshner, J. et al. (2006) Inhibition of transforming growth factor-beta1 signaling attenuates ataxia telangiectasia mutated activity in response to genotoxic stress. Cancer Res., 66, 10861-10869.
-
(2006)
Cancer Res.
, vol.66
, pp. 10861-10869
-
-
Kirshner, J.1
|