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Volumn 107, Issue 23, 2010, Pages 10696-10701

Induction of the Warburg effect by Kaposi's sarcoma herpesvirus is required for the maintenance of latently infected endothelial cells

Author keywords

Gamma herpesvirus; Glycolysis; Human herpesvirus 8; Latency

Indexed keywords

LACTIC ACID;

EID: 77953799148     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1004882107     Document Type: Article
Times cited : (192)

References (31)
  • 1
    • 0038653408 scopus 로고    scopus 로고
    • Molecular genetics of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) epidemiology and pathogenesis
    • DOI 10.1128/MMBR.67.2.175-212.2003
    • Dourmishev LA, Dourmishev AL, Palmeri D, Schwartz RA, Lukac DM (2003) Molecular genetics of Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8) epidemiology and pathogenesis. Microbiol Mol Biol Rev 67:175-212. (Pubitemid 36693471)
    • (2003) Microbiology and Molecular Biology Reviews , vol.67 , Issue.2 , pp. 175-212
    • Dourmishev, L.A.1    Dourmishev, A.L.2    Palmeri, D.3    Schwartz, R.A.4    Lukac, D.M.5
  • 3
    • 50149115756 scopus 로고    scopus 로고
    • Activation of Akt through gp130 receptor signaling is required for Kaposi's sarcoma-associated herpesvirus-induced lymphatic reprogramming of endothelial cells
    • Morris VA, Punjabi AS, Lagunoff M (2008) Activation of Akt through gp130 receptor signaling is required for Kaposi's sarcoma-associated herpesvirus-induced lymphatic reprogramming of endothelial cells. J Virol 82:8771-8779.
    • (2008) J Virol , vol.82 , pp. 8771-8779
    • Morris, V.A.1    Punjabi, A.S.2    Lagunoff, M.3
  • 4
    • 47949101732 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus confers a survival advantage to endothelial cells
    • Wang L, Damania B (2008) Kaposi's sarcoma-associated herpesvirus confers a survival advantage to endothelial cells. Cancer Res 68:4640-4648.
    • (2008) Cancer Res , vol.68 , pp. 4640-4648
    • Wang, L.1    Damania, B.2
  • 5
    • 34247119790 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus induces sustained NF-kappaB activation during de novo infection of primary human dermal microvascular endothelial cells that is essential for viral gene expression
    • DOI 10.1128/JVI.02333-06
    • Sadagopan S, et al. (2007) Kaposi's sarcoma-associated herpesvirus induces sustained NF-kappaB activation during de novo infection of primary human dermal micro-vascular endothelial cells that is essential for viral gene expression. J Virol 81:3949-3968. (Pubitemid 46586891)
    • (2007) Journal of Virology , vol.81 , Issue.8 , pp. 3949-3968
    • Sadagopan, S.1    Sharma-Walia, N.2    Veettil, M.V.3    Raghu, H.4    Sivakumar, R.5    Bottero, V.6    Chandran, B.7
  • 6
    • 33750367972 scopus 로고    scopus 로고
    • Latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells activates hypoxia-induced factors
    • Carroll PA, Kenerson HL, Yeung RS, Lagunoff M (2006) Latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells activates hypoxia-induced factors. J Virol 80:10802-10812.
    • (2006) J Virol , vol.80 , pp. 10802-10812
    • Carroll, P.A.1    Kenerson, H.L.2    Yeung, R.S.3    Lagunoff, M.4
  • 7
    • 0001221508 scopus 로고
    • On respiratory impairment in cancer cells
    • Warburg O (1956) On respiratory impairment in cancer cells. Science 124:269-270.
    • (1956) Science , vol.124 , pp. 269-270
    • Warburg, O.1
  • 8
    • 35649014840 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1
    • DOI 10.1128/MCB.00440-07
    • Kim JW, Gao P, Liu YC, Semenza GL, Dang CV (2007) Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1. Mol Cell Biol 27:7381-7393. (Pubitemid 350033646)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.21 , pp. 7381-7393
    • Kim, J.-W.1    Gao, P.2    Liu, Y.-C.3    Semenza, G.L.4    Dang, C.V.5
  • 9
    • 33644614520 scopus 로고    scopus 로고
    • HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
    • DOI 10.1016/j.cmet.2006.02.002, PII S1550413106000623
    • Kim JW, Tchernyshyov I, Semenza GL, Dang CV (2006) HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia. Cell Metab 3:177-185. (Pubitemid 43316523)
    • (2006) Cell Metabolism , vol.3 , Issue.3 , pp. 177-185
    • Kim, J.-W.1    Tchernyshyov, I.2    Semenza, G.L.3    Dang, C.V.4
  • 10
  • 11
    • 52649107626 scopus 로고    scopus 로고
    • Cancer cell metabolism: Warburg and beyond
    • Hsu PP, Sabatini DM (2008) Cancer cell metabolism: Warburg and beyond. Cell 134: 703-707.
    • (2008) Cell , vol.134 , pp. 703-707
    • Hsu, P.P.1    Sabatini, D.M.2
  • 12
    • 44849137874 scopus 로고    scopus 로고
    • Sugar and fat - that's where it's at: Metabolic changes in tumors
    • Young CD, Anderson SM (2008) Sugar and fat - that's where it's at: Metabolic changes in tumors. Breast Cancer Res 10:202.
    • (2008) Breast Cancer Res , vol.10 , pp. 202
    • Young, C.D.1    Anderson, S.M.2
  • 13
    • 2542561169 scopus 로고    scopus 로고
    • Akt stimulates aerobic glycolysis in cancer cells
    • Elstrom RL, et al. (2004) Akt stimulates aerobic glycolysis in cancer cells. Cancer Res 64: 3892-3899.
    • (2004) Cancer Res , vol.64 , pp. 3892-3899
    • Elstrom, R.L.1
  • 14
    • 34447513075 scopus 로고    scopus 로고
    • Hypoxic regulation of glucose transport, anaerobic metabolism and angiogenesis in cancer: Novel pathways and targets for anticancer therapeutics
    • Airley RE, Mobasheri A (2007) Hypoxic regulation of glucose transport, anaerobic metabolism and angiogenesis in cancer: novel pathways and targets for anticancer therapeutics. Chemotherapy 53:233-256.
    • (2007) Chemotherapy , vol.53 , pp. 233-256
    • Airley, R.E.1    Mobasheri, A.2
  • 15
    • 41149105722 scopus 로고    scopus 로고
    • Mitochondria in cancer cells: What is so special about them?
    • Gogvadze V, Orrenius S, Zhivotovsky B (2008) Mitochondria in cancer cells: What is so special about them? Trends Cell Biol 18:165-173.
    • (2008) Trends Cell Biol , vol.18 , pp. 165-173
    • Gogvadze, V.1    Orrenius, S.2    Zhivotovsky, B.3
  • 16
    • 33746924468 scopus 로고    scopus 로고
    • Hexokinase II: Cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria
    • Mathupala SP, Ko YH, Pedersen PL (2006) Hexokinase II: Cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria. Oncogene 25:4777-4786.
    • (2006) Oncogene , vol.25 , pp. 4777-4786
    • Mathupala, S.P.1    Ko, Y.H.2    Pedersen, P.L.3
  • 17
    • 60249083822 scopus 로고    scopus 로고
    • Hexokinase-2 bound to mitochondria: Cancer's Stygian link to the "Warburg effect" and a pivotal target for effective therapy
    • Mathupala SP, Ko YH, Pedersen PL (2009) Hexokinase-2 bound to mitochondria: Cancer's Stygian link to the "Warburg effect" and a pivotal target for effective therapy. Semin Cancer Biol 19:17-24.
    • (2009) Semin Cancer Biol , vol.19 , pp. 17-24
    • Mathupala, S.P.1    Ko, Y.H.2    Pedersen, P.L.3
  • 18
    • 57449115616 scopus 로고    scopus 로고
    • Tumor metabolism: Cancer cells give and take lactate
    • Semenza GL (2008) Tumor metabolism: Cancer cells give and take lactate. J Clin Invest 118:3835-3837.
    • (2008) J Clin Invest , vol.118 , pp. 3835-3837
    • Semenza, G.L.1
  • 19
    • 69849090667 scopus 로고    scopus 로고
    • Increased OXPHOS activity precedes rise in glycolytic rate in H-RasV12/E1A transformed fibroblasts that develop a Warburg phenotype
    • de Groof AJ, et al. (2009) Increased OXPHOS activity precedes rise in glycolytic rate in H-RasV12/E1A transformed fibroblasts that develop a Warburg phenotype. Mol Cancer 8:54.
    • (2009) Mol Cancer , vol.8 , pp. 54
    • De Groof, A.J.1
  • 20
    • 17844383964 scopus 로고    scopus 로고
    • Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements
    • Ramanathan A, Wang C, Schreiber SL (2005) Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements. Proc Natl Acad Sci USA 102:5992-5997.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 5992-5997
    • Ramanathan, A.1    Wang, C.2    Schreiber, S.L.3
  • 21
    • 0014337517 scopus 로고
    • Effect of oxamate on glycolysis and respiration in sarcoma 37 ascites cells
    • Elwood JC (1968) Effect of oxamate on glycolysis and respiration in sarcoma 37 ascites cells. Cancer Res 28:2056-2060.
    • (1968) Cancer Res , vol.28 , pp. 2056-2060
    • Elwood, J.C.1
  • 22
    • 33644622570 scopus 로고    scopus 로고
    • HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
    • DOI 10.1016/j.cmet.2006.01.012, PII S155041310600060X
    • Papandreou I, Cairns RA, Fontana L, LimA L, Denko NC (2006) HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab 3:187-197. (Pubitemid 43316524)
    • (2006) Cell Metabolism , vol.3 , Issue.3 , pp. 187-197
    • Papandreou, I.1    Cairns, R.A.2    Fontana, L.3    Lim, A.L.4    Denko, N.C.5
  • 23
    • 38149063508 scopus 로고    scopus 로고
    • 2-deoxy-D-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer
    • Coleman MC, et al. (2008) 2-deoxy-D-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer. Free Radic Biol Med 44:322-331.
    • (2008) Free Radic Biol Med , vol.44 , pp. 322-331
    • Coleman, M.C.1
  • 24
    • 0035826677 scopus 로고    scopus 로고
    • Hypersensitization of tumor cells to glycolytic inhibitors
    • DOI 10.1021/bi002426w
    • Liu H, Hu YP, Savaraj N, Priebe W, Lampidis TJ (2001) Hypersensitization of tumor cells to glycolytic inhibitors. Biochemistry 40:5542-5547. (Pubitemid 32458256)
    • (2001) Biochemistry , vol.40 , Issue.18 , pp. 5542-5547
    • Liu, H.1    Hu, Y.P.2    Savaraj, N.3    Priebe, W.4    Lampidis, T.J.5
  • 25
    • 27644477839 scopus 로고    scopus 로고
    • Establishment and maintenance of Kaposi's sarcoma-associated herpesvirus latency in B cells
    • DOI 10.1128/JVI.79.22.14383-14391.2005
    • Chen L, Lagunoff M (2005) Establishment and maintenance of Kaposi's sarcomaassociated herpesvirus latency in B cells. J Virol 79:14383-14391. (Pubitemid 41552735)
    • (2005) Journal of Virology , vol.79 , Issue.22 , pp. 14383-14391
    • Chen, L.1    Lagunoff, M.2
  • 26
    • 0014320511 scopus 로고
    • Glycolysis in chick embryo cell cultures transformed by Rous sarcoma virus
    • Steck TL, Kaufman S, Bader JP (1968) Glycolysis in chick embryo cell cultures transformed by Rous sarcoma virus. Cancer Res 28:1611-1619.
    • (1968) Cancer Res , vol.28 , pp. 1611-1619
    • Steck, T.L.1    Kaufman, S.2    Bader, J.P.3
  • 27
    • 0016230184 scopus 로고
    • Glycolysis during early infection of feline and human cells with feline leukemia virus
    • Bardell D, Essex M (1974) Glycolysis during early infection of feline and human cells with feline leukemia virus. Infect Immun 9:824-827.
    • (1974) Infect Immun , vol.9 , pp. 824-827
    • Bardell, D.1    Essex, M.2
  • 28
    • 33845970245 scopus 로고    scopus 로고
    • Dynamics of the cellular metabolome during human cytomegalovirus infection
    • DOI 10.1371/journal.ppat.0020132
    • Munger J, Bajad SU, Coller HA, Shenk T, Rabinowitz JD (2006) Dynamics of the cellular metabolome during human cytomegalovirus infection. PLoS Pathog 2:e132. (Pubitemid 46045203)
    • (2006) PLoS Pathogens , vol.2 , Issue.12 , pp. 1165-1175
    • Munger, J.1    Bajad, S.U.2    Coller, H.A.3    Shenk, T.4    Rabinowitz, J.D.5
  • 30
    • 20144367584 scopus 로고    scopus 로고
    • Sirolimus for Kaposi's sarcoma in renal-transplant recipients
    • Stallone G, et al. (2005) Sirolimus for Kaposi's sarcoma in renal-transplant recipients. N Engl J Med 352:1317-1323.
    • (2005) N Engl J Med , vol.352 , pp. 1317-1323
    • Stallone, G.1
  • 31
    • 33847235341 scopus 로고    scopus 로고
    • Persistent activation of STAT3 by latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells
    • Punjabi AS, Carroll PA, Chen L, Lagunoff M (2007) Persistent activation of STAT3 by latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells. J Virol 81:2449-2458.
    • (2007) J Virol , vol.81 , pp. 2449-2458
    • Punjabi, A.S.1    Carroll, P.A.2    Chen, L.3    Lagunoff, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.