Butyric acid induces apoptosis via oxidative stress in jurkat T-cells

Journal of Dental Research

Volumn 89, Issue 7, 2010, Pages 689-694

  Kurita Ochiai, T ^a   Ochiai, K ^a  

^a NIHON UNIVERSITY   (Japan)

Author keywords

Apoptosis; Butyric acid; N acetyl L Cysteine; Periodontitis; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; AIFM1 PROTEIN, HUMAN; APOPTOSIS INDUCING FACTOR; BAD PROTEIN, HUMAN; BCL2L1 PROTEIN, HUMAN; BUTYRIC ACID; CASP10 PROTEIN, HUMAN; CASP4 PROTEIN, HUMAN; CASPASE 10; CYSTEINE PROTEINASE INHIBITOR; CYTOCHROME C; DEATH RECEPTOR; DIABLO PROTEIN, HUMAN; FLICE INHIBITORY PROTEIN; HEAT SHOCK PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN; INITIATOR CASPASE; INTERLEUKIN 1BETA CONVERTING ENZYME INHIBITOR; INTERLEUKIN-1BETA-CONVERTING ENZYME INHIBITOR; MITOCHONDRIAL PROTEIN; MOLECULAR CHAPERONE GRP78; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL X; REACTIVE OXYGEN METABOLITE; SCAVENGER; SERINE PROTEINASE INHIBITOR; SIGNAL PEPTIDE; VIRUS PROTEIN;

APOPTOSIS; ARTICLE; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ENDOPLASMIC RETICULUM; HUMAN; LEUKEMIA CELL LINE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; OXIDATIVE STRESS; PHYSIOLOGY; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ACETYLCYSTEINE; APOPTOSIS; APOPTOSIS INDUCING FACTOR; BCL-2-ASSOCIATED X PROTEIN; BCL-ASSOCIATED DEATH PROTEIN; BCL-X PROTEIN; BUTYRIC ACID; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CASPASE 10; CASPASES, INITIATOR; CYSTEINE PROTEINASE INHIBITORS; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM; FREE RADICAL SCAVENGERS; HEAT-SHOCK PROTEINS; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JURKAT CELLS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; RECEPTORS, DEATH DOMAIN; SERPINS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; VIRAL PROTEINS;

EID: 77953791579     PISSN: 00220345     EISSN: 15440591     Source Type: Journal    
DOI: 10.1177/0022034510365456     Document Type: Article

References (29)

1. Botta GA, Radin L., Costa A., Schito G., Blasi G. (1985). Gas-liquid chromatography of the gingival fluid as an aid in periodontal diagnosis. J Periodontal Res 20: 450-457.
2. Budd RC, Yeh WC, Tschopp J. (2006). C-FLIP regulation of lymphocyte activation and development. Nat Rev Immunol 6: 196-204.
3. Budihardjo I., Oliver H., Lutter M., Luo X., Wang X. (1999). Biochemical pathways of caspase activation during apoptosis. Annu Rev Cell Dev Biol 15: 269-290.
4. CanakÇi CF, CiÇek Y., CanakÇi V. (2005). Reactive oxygen species and human inflammatory periodontal diseases. Biochemistry 70: 619-628. (Pubitemid 41118160)
5. Dickhout JG, Hossain GS, Pozza LM, Zhou J., Lhotak S., Austin RC (2005). Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium implications in atherogenesis. Arterioscler Thromb Vasc Biol 25: 2623-2629.
6. Ellis SD, Tucci MA, Serio FG, Johnson RB (1998). Factors for progression of periodontal disease. J Oral Pathol Med 27: 101-105.
7. Filomenko R., Prévotat L., Rébé C., Cortier M., Jeannin JF, Solary E., et al. (2006). Caspase-10 involvement in cytotoxic drug-induced apoptosis of tumor cells. Oncogene 25: 7635-7645.
8. Foyouzi-Youssefi R., Arnaudeau S., Borner C., Kelly WL, Tschopp J., Lew DP, et al. (2000). Bcl-2 decreases the free Ca2+ concentration within the endoplasmic reticulum. Proc Natl Acad Sci USA 97: 5723-5728.
9. Haynes CM, Titus EA, Cooper AA (2004). Degradation of misfolded proteins prevents Er-derived oxidative stress and cell death. Mol Cell 15: 767-776.
10. Hitomi J., Katayama T., Eguchi Y., Kudo T., Taniguchi M., Koyama Y., et al. (2004). Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Ab-induced cell death. J Cell Biol 165: 347-356.
11. Jun DY, Kim JS, Park HS, Han CR, Fang Z., Woo MH, et al. (2007). Apoptogenic activity of auraptene of Zanthoxylum schinifolium toward human acute leukemia Jurkat cells is associated with ER stress-mediated caspase-8 activation that stimulates mitochondria-dependent or -independent caspase cascade. Carcinogenesis 28: 1303-1313.
12. Kurita-Ochiai T., Fukushima K., Ochiai K. (1997). Butyric acid-induced apoptosis of murine thymocytes, splenic T cells, and human Jurkat T cells. Infect Immun 65: 35-41.
13. Kurita-Ochiai T., Fukushima K., Ochiai K. (1998). Volatile fatty acid, a metabolic by-product of periodontopathic bacteria, induces apoptosis in WEHI 231 and RAJI B lymphoma cells and splenic B cells. Infect Immun 66: 2587-2594.
14. Kurita-Ochiai T., Ochiai K., Fukushima K. (2001). Butyric acid-induced T-cell apoptosis is mediated by caspase-8 and -9 activation in a Fas-independent manner. Clin Diagn Lab Immunol 8: 325-332.
15. Kurita-Ochiai T., Amano S., Fukushima K., Ochiai K. (2003). Cellular events involved in butyric acid-induced T cell apoptosis. J Immunol 171: 3576-3584.
16. Kurita-Ochiai T., Hashizume T., Yonezawa H., Ochiai K., Yamamoto M. (2006). Characterization of the effects of butyric acid on cell proliferation, cell cycle distribution and apoptosis. FEMS Immunol Med Microbiol 47: 67-74.
17. Kurita-Ochiai T., Seto S., Suzuki N., Yamamoto M., Otsuka K., Abe K., et al. (2008). Butyric acid induces apoptosis in inflamed fibroblasts. J Dent Res 87: 51-55.
18. Lai MT, Huang KL, Chang WM, Lai YK (2003). Geldanamycin induction of grp78 requires activation of reactive oxygen species via ER stress responsive elements in 9L rat brain tumor cells. Cell Signal 15: 585-595.
19. Lee YS, Bak EJ, Kim M., Park W., Seo JT, Yoo YJ (2008). Induction of IL-8 in periodontal ligament cells by H(2)O(2). J Microbiol 46: 579-584.
20. Margolis HC, Duckworth JH, Moreno EC (1988). Composition and buffer capacity of pooled starved plaque fluid from caries-free and caries-susceptible individuals. J Dent Res 67: 1476-1482.
21. Maslowski KM, Vieira AT, Ng A., Kranich J., Sierro F., Yu D., et al. (2009). Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43. Nature 461: 1282-1286.
22. Matthews JB, Wright HJ, Roberts A., Ling-Mountford N., Cooper PR, Chapple IL (2007). Neutrophil hyper-responsiveness in periodontitis. J Dent Res 86: 718-722.
23. Nakajima A., Kojima Y., Nakayama M., Yagita H., Okumura K., Nakano H. (2008). Downregulation of C-FLIP promotes caspase-dependent JNK activation and reactive oxygen species accumulation in tumor cells. Oncogene 27: 76-84.
24. Nieto-Miguel T., Fonteriz RI, Vay L., Gajate C., Lopéz-Hernandez S., Mollinedo F. (2007). Endoplasmic reticulum stress in the proapoptotic action of edelfosine in solid tumor cells. Cancer Res 67: 10368-10378.
25. Rahmani M., Davis EM, Crabtree TR, Habibi JR, Nguyen TK, Dent P., et al. (2007). The kinase inhibitor sorafenib induces cell death through a process involving induction of endoplasmic reticulum stress. Mol Cell Biol 27: 5499-5513.
26. Rao RV, Ellerby HM, Bredesen DE (2004). Coupling endoplasmic reticulum stress to the cell death program. Cell Death Differ 11: 372-380.
27. Scorrano L., Oakes SA, Opferman JT, Cheng EH, Sorcinelli MD, Pozzan T., et al. (2003). BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis. Science 300: 135-139.
28. Seto S., Kurita-Ochiai T., Ochiai K. (2008). Increased susceptibility to tumor necrosis factor-alpha in butyric acid-induced apoptosis is caused by downregulation of cFLIP expression in Jurkat T cells. Microbiol Immunol 52: 188-196.
29. Sugano N., Kawamoto K., Numazaki H., Murai S., Ito K. (2000). Detection of mitochondrial DNA mutations in human gingival tissues. J Oral Sci 42: 221-223.