The nuclear receptor FXR is expressed in pancreatic β-cells and protects human islets from lipotoxicity

FEBS Letters

Volumn 584, Issue 13, 2010, Pages 2845-2851

  Popescu, Iuliana Ristea ^a,b,c   Helleboid Chapman, Audrey ^a,b,c   Lucas, Anthony ^a,b,c   Vandewalle, Brigitte ^a,d   Dumont, Julie ^a,b,c   Bouchaert, Emmanuel ^a,b,c   Derudas, Bruno ^a,b,c   Kerr Conte, Julie ^a,d   Caron, Sandrine ^a,b,c   Pattou, François ^a,d   Staels, Bart ^a,b,c  

^a UNIV LILLE   (France)

^b INSERM UMR1011 ^*  (France)

^c INSTITUT PASTEUR DE LILLE   (France)

^d INSERM   (France)

Author keywords

Farnesoid X receptor; Islet; Lipotoxicity; Type 2 diabetes

Indexed keywords

FARNESOID X RECEPTOR; GLUCOSE; INSULIN; LIPID;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL ISOLATION; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; GENE EXPRESSION; HUMAN; HUMAN CELL; INSULIN RELEASE; LIPID METABOLISM; LIPOTOXICITY; MALE; METABOLIC STRESS; MOUSE; NONHUMAN; OBESITY; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; HUMANS; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; ISOXAZOLES; MALE; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; OBESITY; PALMITIC ACID; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR;

MUS;

EID: 77953708142     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.04.068     Document Type: Article

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