메뉴 건너뛰기




Volumn 185, Issue 1, 2010, Pages 43-49

Biomarkers of cartilage turnover. Part 2: Non-collagenous markers

Author keywords

Biomarkers; Metabolomics; Osteoarthritis; Proteoglycans

Indexed keywords

AGGRECAN; AGGRECANASE 1; AGGRECANASE 2; BIOLOGICAL MARKER; CARTILAGE OLIGOMERIC MATRIX PROTEIN; CHONDROITIN SULFATE; EPITOPE; FIBRONECTIN; GLYCOPROTEIN; KERATAN SULFATE; LINK PROTEIN; MONOCLONAL ANTIBODY; PROTEOGLYCAN; THROMBOSPONDIN; COLLAGEN TYPE 2; MATRILIN; SCLEROPROTEIN;

EID: 77953670237     PISSN: 10900233     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tvjl.2010.04.012     Document Type: Review
Times cited : (34)

References (101)
  • 1
    • 11844256439 scopus 로고    scopus 로고
    • Analysis of cartilage oligomeric matrix protein (COMP) degradation and synthesis in equine joint disease
    • Arai K., Misumi K., Carter S.D., Shinbara S., Fujiki M., Sakamoto H. Analysis of cartilage oligomeric matrix protein (COMP) degradation and synthesis in equine joint disease. Equine Veterinary Journal 2005, 37:31-36.
    • (2005) Equine Veterinary Journal , vol.37 , pp. 31-36
    • Arai, K.1    Misumi, K.2    Carter, S.D.3    Shinbara, S.4    Fujiki, M.5    Sakamoto, H.6
  • 2
    • 0029745749 scopus 로고    scopus 로고
    • The development of articular-cartilage: II. The spatial and temporal patterns of glycosaminoglycans and small leucine-rich proteoglycans
    • Archer C.W., Morrison E.H., Bayliss M.T., Ferguson M.W. The development of articular-cartilage: II. The spatial and temporal patterns of glycosaminoglycans and small leucine-rich proteoglycans. Journal of Anatomy 1996, 189:23-35.
    • (1996) Journal of Anatomy , vol.189 , pp. 23-35
    • Archer, C.W.1    Morrison, E.H.2    Bayliss, M.T.3    Ferguson, M.W.4
  • 3
    • 0028431792 scopus 로고
    • Measurement of glycosaminoglycans and keratan sulfate in canine arthropathies
    • Arican M., Carter S.D., Bennett D., May C. Measurement of glycosaminoglycans and keratan sulfate in canine arthropathies. Research in Veterinary Science 1994, 56:290-297.
    • (1994) Research in Veterinary Science , vol.56 , pp. 290-297
    • Arican, M.1    Carter, S.D.2    Bennett, D.3    May, C.4
  • 4
    • 0023895967 scopus 로고
    • Spontaneous cartilage degeneration in guinea pigs
    • Bendele A.M., Hulman J.F. Spontaneous cartilage degeneration in guinea pigs. Arthritis and Rheumatism 1988, 31:561-565.
    • (1988) Arthritis and Rheumatism , vol.31 , pp. 561-565
    • Bendele, A.M.1    Hulman, J.F.2
  • 5
    • 0030974710 scopus 로고    scopus 로고
    • Synovial fluid chondroitin and keratan sulfate epitopes, glycosaminoglycans and hyaluronan in arthritic and normal knees
    • Blecher C., Yaqub R., Fawthrop F. Synovial fluid chondroitin and keratan sulfate epitopes, glycosaminoglycans and hyaluronan in arthritic and normal knees. Annals of the Rheumatic Diseases 1997, 56:299-307.
    • (1997) Annals of the Rheumatic Diseases , vol.56 , pp. 299-307
    • Blecher, C.1    Yaqub, R.2    Fawthrop, F.3
  • 6
    • 0024318683 scopus 로고
    • Lack of association between serum keratan sulfate concentrations and cartilage changes of osteoarthritis after transection of the anterior cruciate ligament in the dog
    • Brandt K.D., Thonar E.J.M. Lack of association between serum keratan sulfate concentrations and cartilage changes of osteoarthritis after transection of the anterior cruciate ligament in the dog. Arthritis and Rheumatism 1989, 32:647-651.
    • (1989) Arthritis and Rheumatism , vol.32 , pp. 647-651
    • Brandt, K.D.1    Thonar, E.J.M.2
  • 8
  • 9
    • 0036148714 scopus 로고    scopus 로고
    • Synovial fluid biomarker levels predict articular cartilage damage following complete medial meniscectomy in the canine knee
    • Carlson C.S., Guilak F., Vail T.P., Gardin J.F., Kraus V.B. Synovial fluid biomarker levels predict articular cartilage damage following complete medial meniscectomy in the canine knee. Journal of Orthopaedic Research 2002, 20:92-100.
    • (2002) Journal of Orthopaedic Research , vol.20 , pp. 92-100
    • Carlson, C.S.1    Guilak, F.2    Vail, T.P.3    Gardin, J.F.4    Kraus, V.B.5
  • 11
    • 0000444570 scopus 로고
    • Immunological markers of cartilage proteoglycans metabolism in animal and human osteoarthritis
    • Raven Press, New York, NY, USA, K.E. Kuettner (Ed.)
    • Caterson B., Hughes C.E., Johnstone B. Immunological markers of cartilage proteoglycans metabolism in animal and human osteoarthritis. Articular Cartilage and Osteoarthritis 1992, 415-427. Raven Press, New York, NY, USA. K.E. Kuettner (Ed.).
    • (1992) Articular Cartilage and Osteoarthritis , pp. 415-427
    • Caterson, B.1    Hughes, C.E.2    Johnstone, B.3
  • 13
    • 42149127678 scopus 로고    scopus 로고
    • Change in serum measurements of cartilage oligomeric matrix protein and association with the development and worsening of radiographic hip osteoarthritis
    • Chaganti R.K., Kelman A., Lui L., Yao W., Javaid M.K., Bauer D., Nevitt M., Lane N.E. Change in serum measurements of cartilage oligomeric matrix protein and association with the development and worsening of radiographic hip osteoarthritis. Osteoarthritis and Cartilage 2008, 16:566-571.
    • (2008) Osteoarthritis and Cartilage , vol.16 , pp. 566-571
    • Chaganti, R.K.1    Kelman, A.2    Lui, L.3    Yao, W.4    Javaid, M.K.5    Bauer, D.6    Nevitt, M.7    Lane, N.E.8
  • 14
    • 0034820293 scopus 로고    scopus 로고
    • A sensitive assay for the measurement of serum chondroitin sulfate 3B3(-) epitope levels in human rheumatic diseases
    • Chan S.S., Kent G.N., Will R.K. A sensitive assay for the measurement of serum chondroitin sulfate 3B3(-) epitope levels in human rheumatic diseases. Clinical and Experimental Rheumatology 2001, 19:533-540.
    • (2001) Clinical and Experimental Rheumatology , vol.19 , pp. 533-540
    • Chan, S.S.1    Kent, G.N.2    Will, R.K.3
  • 15
    • 38449098846 scopus 로고    scopus 로고
    • Measurement of glycosaminoglycan release from cartilage explants
    • Humana Press, Totowa, NJ, USA, J.S. Mort, P.J. Roughley (Eds.)
    • Cope A.P. Measurement of glycosaminoglycan release from cartilage explants. Arthritis Research 2007, 201-209. Humana Press, Totowa, NJ, USA. J.S. Mort, P.J. Roughley (Eds.).
    • (2007) Arthritis Research , pp. 201-209
    • Cope, A.P.1
  • 16
    • 0032922885 scopus 로고    scopus 로고
    • Comparative study of normal and osteoarthritic canine synovial fluid using 500MHz 1H magnetic resonance spectroscopy
    • Damyanovich A.Z., Staples J.R., Chan A.D., Marshall K.W. Comparative study of normal and osteoarthritic canine synovial fluid using 500MHz 1H magnetic resonance spectroscopy. Journal of Orthopaedic Research 1999, 17:223-231.
    • (1999) Journal of Orthopaedic Research , vol.17 , pp. 223-231
    • Damyanovich, A.Z.1    Staples, J.R.2    Chan, A.D.3    Marshall, K.W.4
  • 17
    • 0033084199 scopus 로고    scopus 로고
    • 1H MNR investigation of changes in the metabolic profile of synovial fluid in bilateral canine osteoarthritis with unilateral joint denervation
    • Damyanovich A.Z., Staples J.R., Chan A.D., Marshall K.W. 1H MNR investigation of changes in the metabolic profile of synovial fluid in bilateral canine osteoarthritis with unilateral joint denervation. Osteoarthritis and Cartilage 1999, 7:165-172.
    • (1999) Osteoarthritis and Cartilage , vol.7 , pp. 165-172
    • Damyanovich, A.Z.1    Staples, J.R.2    Chan, A.D.3    Marshall, K.W.4
  • 18
    • 0028090357 scopus 로고
    • Cartilage oligomeric matrix protein (COMP) is an abundant component of tendon
    • DiCesare P., Hauser N., Lehman D., Pasumarti S., Paulsson M. Cartilage oligomeric matrix protein (COMP) is an abundant component of tendon. FEBS Letters 1994, 354:237-240.
    • (1994) FEBS Letters , vol.354 , pp. 237-240
    • DiCesare, P.1    Hauser, N.2    Lehman, D.3    Pasumarti, S.4    Paulsson, M.5
  • 19
    • 0030482992 scopus 로고    scopus 로고
    • Increased degradation and altered tissue distribution of cartilage oligomeric matrix protein in human rheumatoid and osteoarthritic cartilage
    • Di Cesare P.E., Carlson C.S.N., Stolerman E.S., Hauser N., Tulli H., Paulsson M. Increased degradation and altered tissue distribution of cartilage oligomeric matrix protein in human rheumatoid and osteoarthritic cartilage. Journal of Orthopaedic Research 1996, 14:946-955.
    • (1996) Journal of Orthopaedic Research , vol.14 , pp. 946-955
    • Di Cesare, P.E.1    Carlson, C.S.N.2    Stolerman, E.S.3    Hauser, N.4    Tulli, H.5    Paulsson, M.6
  • 20
    • 0022552896 scopus 로고
    • Improved quantitation and discrimination of sulfated glycosaminoglycans by use of dimethylmethylene blue
    • Farndale R.W., Buttle D.J., Barrett A.J. Improved quantitation and discrimination of sulfated glycosaminoglycans by use of dimethylmethylene blue. Biochemica et Biophysica Acta 1986, 883:173-177.
    • (1986) Biochemica et Biophysica Acta , vol.883 , pp. 173-177
    • Farndale, R.W.1    Buttle, D.J.2    Barrett, A.J.3
  • 21
    • 0030939541 scopus 로고    scopus 로고
    • Chondroitin and keratan sulfate epitopes, glycosaminoglycans, and hyaluronan in progressive versus non-progressive osteoarthritis
    • Fawthrop F., Yaqub R., Belcher C., Bayliss M., Doherty M. Chondroitin and keratan sulfate epitopes, glycosaminoglycans, and hyaluronan in progressive versus non-progressive osteoarthritis. Annals of the Rheumatic Diseases 1997, 56:119-122.
    • (1997) Annals of the Rheumatic Diseases , vol.56 , pp. 119-122
    • Fawthrop, F.1    Yaqub, R.2    Belcher, C.3    Bayliss, M.4    Doherty, M.5
  • 22
    • 77953685080 scopus 로고
    • Extracellular matrix of cartilage, Glycoproteins
    • Marcel Dekker, New York, NY, USA, J.F. Woessner, D.S. Howell (Eds.)
    • Fife G., Brandt K.D. Extracellular matrix of cartilage, Glycoproteins. Joint Cartilage Degradation 1993, 139-158. Marcel Dekker, New York, NY, USA. J.F. Woessner, D.S. Howell (Eds.).
    • (1993) Joint Cartilage Degradation , pp. 139-158
    • Fife, G.1    Brandt, K.D.2
  • 23
    • 0033608160 scopus 로고    scopus 로고
    • Articular cartilage superficial zone protein (SZP) is homologous to megakaryocyte stimulating factor precursor and is a multifunctional proteoglycan with potential growth-promoting, cytoprotective, and lubricating properties in cartilage metabolism
    • Flannery C.R., Hughes C.E., Schumacher B.L., Tudor D., Aydelotte M.B., Kuettner K.E., Caterson B. Articular cartilage superficial zone protein (SZP) is homologous to megakaryocyte stimulating factor precursor and is a multifunctional proteoglycan with potential growth-promoting, cytoprotective, and lubricating properties in cartilage metabolism. Biochemical and Biophysical Research Communications 1999, 254:535-541.
    • (1999) Biochemical and Biophysical Research Communications , vol.254 , pp. 535-541
    • Flannery, C.R.1    Hughes, C.E.2    Schumacher, B.L.3    Tudor, D.4    Aydelotte, M.B.5    Kuettner, K.E.6    Caterson, B.7
  • 25
    • 0035128614 scopus 로고    scopus 로고
    • Cross-sectional comparison of synovial fluid biochemical markers in equine osteoarthritis and the correlation of these markers with articular cartilage damage
    • Fuller C.J., Barr A.R., Sharif M., Dieppe P.A. Cross-sectional comparison of synovial fluid biochemical markers in equine osteoarthritis and the correlation of these markers with articular cartilage damage. Osteoarthritis and Cartilage 2001, 9:49-55.
    • (2001) Osteoarthritis and Cartilage , vol.9 , pp. 49-55
    • Fuller, C.J.1    Barr, A.R.2    Sharif, M.3    Dieppe, P.A.4
  • 26
    • 0032217320 scopus 로고    scopus 로고
    • Inhibition of interleukin-1a-induced cartilage oligomeric matrix protein degradation in bovine articular cartilage by matrix metalloproteinase inhibitors, potential role for matrix metalloproteinases in the generation of cartilage oligomeric matrix protein fragments in arthritic synovial fluid
    • Ganu V., Goldberg R., Peppard J., Rediske J., Melton R., Hu S.-I. Inhibition of interleukin-1a-induced cartilage oligomeric matrix protein degradation in bovine articular cartilage by matrix metalloproteinase inhibitors, potential role for matrix metalloproteinases in the generation of cartilage oligomeric matrix protein fragments in arthritic synovial fluid. Arthritis and Rheumatism 1998, 41:2143-2151.
    • (1998) Arthritis and Rheumatism , vol.41 , pp. 2143-2151
    • Ganu, V.1    Goldberg, R.2    Peppard, J.3    Rediske, J.4    Melton, R.5    Hu, S.-I.6
  • 27
    • 43249110655 scopus 로고    scopus 로고
    • MT3-MMP (MMP-16) is downregulated by in vitro cytokine stimulation of cartilage, but unaltered in naturally occurring equine osteoarthritis and osteochondrosis
    • Garvican E.R., Vaughan-Thomas A., Redmond C., Clegg P.D. MT3-MMP (MMP-16) is downregulated by in vitro cytokine stimulation of cartilage, but unaltered in naturally occurring equine osteoarthritis and osteochondrosis. Connective Tissue Research 2008, 49:62-67.
    • (2008) Connective Tissue Research , vol.49 , pp. 62-67
    • Garvican, E.R.1    Vaughan-Thomas, A.2    Redmond, C.3    Clegg, P.D.4
  • 28
    • 77953664216 scopus 로고    scopus 로고
    • Biomarkers of cartilage turnover. part 1: markers of collagen degradation and synthesis
    • Garvican E.R., Vaughan-Thomas A., Innes J.F., Clegg P.D. Biomarkers of cartilage turnover. part 1: markers of collagen degradation and synthesis. The Veterinary Journal 2010, 185:36-42.
    • (2010) The Veterinary Journal , vol.185 , pp. 36-42
    • Garvican, E.R.1    Vaughan-Thomas, A.2    Innes, J.F.3    Clegg, P.D.4
  • 30
    • 0022619555 scopus 로고
    • Age-related changes protein-related epitopes of human articular-cartilage proteoglycans
    • Glant T.T., Mikecz K., Roughley P.J., Buzas E., Poole A.R. Age-related changes protein-related epitopes of human articular-cartilage proteoglycans. Biochemical Journal 1986, 236:71-75.
    • (1986) Biochemical Journal , vol.236 , pp. 71-75
    • Glant, T.T.1    Mikecz, K.2    Roughley, P.J.3    Buzas, E.4    Poole, A.R.5
  • 31
    • 15844413814 scopus 로고    scopus 로고
    • Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis
    • Glasson S.S., Askew R., Sheppard B. Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis. Nature 2005, 434:644-648.
    • (2005) Nature , vol.434 , pp. 644-648
    • Glasson, S.S.1    Askew, R.2    Sheppard, B.3
  • 33
    • 0026507880 scopus 로고
    • Review, Proteoglycans, many forms and many functions
    • Hardingham T.E., Fosang A.J. Review, Proteoglycans, many forms and many functions. The FASEB Journal 1992, 6:861-870.
    • (1992) The FASEB Journal , vol.6 , pp. 861-870
    • Hardingham, T.E.1    Fosang, A.J.2
  • 34
    • 0029098989 scopus 로고
    • Changes in glycosaminoglycan epitope levels in knee joint fluid following injury
    • Hazell P.K., Dent C., Fairclough J.A. Changes in glycosaminoglycan epitope levels in knee joint fluid following injury. Arthritis and Rheumatism 1995, 38:953-959.
    • (1995) Arthritis and Rheumatism , vol.38 , pp. 953-959
    • Hazell, P.K.1    Dent, C.2    Fairclough, J.A.3
  • 36
    • 0036711769 scopus 로고    scopus 로고
    • Biomarkers of joint tissue metabolism in canine osteoarthritic and arthritic joint disorders
    • Hegemann N., Kohn B., Brunnberg L., Schmidt M.F. Biomarkers of joint tissue metabolism in canine osteoarthritic and arthritic joint disorders. Osteoarthritis and Cartilage 2002, 10:714-721.
    • (2002) Osteoarthritis and Cartilage , vol.10 , pp. 714-721
    • Hegemann, N.1    Kohn, B.2    Brunnberg, L.3    Schmidt, M.F.4
  • 38
    • 0036794312 scopus 로고    scopus 로고
    • A comparative analysis of bone and cartilage metabolism in two strains of guinea-pig with varying degrees of naturally occurring osteoarthritis
    • Huebner J.L., Hanes M.A., Beekman B., TeKoppele J.M., Kraus V.B. A comparative analysis of bone and cartilage metabolism in two strains of guinea-pig with varying degrees of naturally occurring osteoarthritis. Osteoarthritis and Cartilage 2002, 10:758-767.
    • (2002) Osteoarthritis and Cartilage , vol.10 , pp. 758-767
    • Huebner, J.L.1    Hanes, M.A.2    Beekman, B.3    TeKoppele, J.M.4    Kraus, V.B.5
  • 39
    • 0028919163 scopus 로고
    • Monoclonal antibodies that specifically recognise neoepitope sequences generated by aggrecanase and matrix metalloproteinase cleavage of aggrecan-application to catabolism in situ and in vitro
    • Hughes C.E., Caterson B., Fosang A.J. Monoclonal antibodies that specifically recognise neoepitope sequences generated by aggrecanase and matrix metalloproteinase cleavage of aggrecan-application to catabolism in situ and in vitro. Biochemistry Journal 1995, 305:799-804.
    • (1995) Biochemistry Journal , vol.305 , pp. 799-804
    • Hughes, C.E.1    Caterson, B.2    Fosang, A.J.3
  • 41
    • 0032252038 scopus 로고    scopus 로고
    • Relations between biochemical markers of osteoarthritis and other disease parameters in a population of dogs with naturally acquired osteoarthritis of the genual joint
    • Innes J.F., Sharif M., Barr A.R.S. Relations between biochemical markers of osteoarthritis and other disease parameters in a population of dogs with naturally acquired osteoarthritis of the genual joint. American Journal of Veterinary Research 1998, 59:1530-1536.
    • (1998) American Journal of Veterinary Research , vol.59 , pp. 1530-1536
    • Innes, J.F.1    Sharif, M.2    Barr, A.R.S.3
  • 42
    • 0033193125 scopus 로고    scopus 로고
    • Changes in concentrations of biochemical markers of osteoarthritis following surgical repair of ruptured cranial cruciate ligaments in dogs
    • Innes J.F., Sharif M., Barr A.R.S. Changes in concentrations of biochemical markers of osteoarthritis following surgical repair of ruptured cranial cruciate ligaments in dogs. American Journal of Veterinary Research 1999, 60:1164-1168.
    • (1999) American Journal of Veterinary Research , vol.60 , pp. 1164-1168
    • Innes, J.F.1    Sharif, M.2    Barr, A.R.S.3
  • 43
    • 27844543298 scopus 로고    scopus 로고
    • Products resulting from cleavage of the interglobular domain of aggrecan in samples of synovial fluid collected from dogs with early- and late-stage osteoarthritis
    • Innes J.F., Little C.B., Hughes C.E., Caterson B. Products resulting from cleavage of the interglobular domain of aggrecan in samples of synovial fluid collected from dogs with early- and late-stage osteoarthritis. American Journal of Veterinary Research 2005, 66:1679-1685.
    • (2005) American Journal of Veterinary Research , vol.66 , pp. 1679-1685
    • Innes, J.F.1    Little, C.B.2    Hughes, C.E.3    Caterson, B.4
  • 44
    • 0035318579 scopus 로고    scopus 로고
    • Concentration of chondroitin sulfate epitopes 3B3 and 7D4 in synovial fluid after intra-articular and extracapsular reconstruction of the cranial cruciate ligament in dogs
    • Johnson K.A., Hay C.W., Chu Q., Kochevar D., Hulse D.A. Concentration of chondroitin sulfate epitopes 3B3 and 7D4 in synovial fluid after intra-articular and extracapsular reconstruction of the cranial cruciate ligament in dogs. American Journal of Veterinary Research 2001, 62:581-587.
    • (2001) American Journal of Veterinary Research , vol.62 , pp. 581-587
    • Johnson, K.A.1    Hay, C.W.2    Chu, Q.3    Kochevar, D.4    Hulse, D.A.5
  • 45
    • 0036017286 scopus 로고    scopus 로고
    • Cartilage-derived biomarkers of osteoarthritis in synovial fluid of dogs with naturally acquired rupture of the cranial cruciate ligament
    • Johnson K.A., Hay C.W., Chu Q., Roe S.C., Caterson B. Cartilage-derived biomarkers of osteoarthritis in synovial fluid of dogs with naturally acquired rupture of the cranial cruciate ligament. American Journal of Veterinary Research 2002, 63:775-781.
    • (2002) American Journal of Veterinary Research , vol.63 , pp. 775-781
    • Johnson, K.A.1    Hay, C.W.2    Chu, Q.3    Roe, S.C.4    Caterson, B.5
  • 50
    • 2542567204 scopus 로고    scopus 로고
    • Increased stromelysin-1 (MMP-3), proteoglycan degradation (3B3- and 7D4) and collagen damage in cyclically load-injured articular cartilage
    • Lin P., Chen C., Torzilli P.A. Increased stromelysin-1 (MMP-3), proteoglycan degradation (3B3- and 7D4) and collagen damage in cyclically load-injured articular cartilage. Osteoarthritis and Cartilage 2004, 12:485-496.
    • (2004) Osteoarthritis and Cartilage , vol.12 , pp. 485-496
    • Lin, P.1    Chen, C.2    Torzilli, P.A.3
  • 53
    • 0030688870 scopus 로고    scopus 로고
    • Histomorphological and immunohistochemical evaluation of joint changes in a model of osteoarthritis induced by lateral meniscectomy in sheep
    • Little C., Smith S., Ghosh P. Histomorphological and immunohistochemical evaluation of joint changes in a model of osteoarthritis induced by lateral meniscectomy in sheep. Journal of Rheumatology 1997, 24:2199-2209.
    • (1997) Journal of Rheumatology , vol.24 , pp. 2199-2209
    • Little, C.1    Smith, S.2    Ghosh, P.3
  • 54
    • 0033571592 scopus 로고    scopus 로고
    • Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro
    • Little C.B., Flannery C.R., Hughes C.E., Goodship A., Caterson B. Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro. Biochemical Journal 1999, 344:61-68.
    • (1999) Biochemical Journal , vol.344 , pp. 61-68
    • Little, C.B.1    Flannery, C.R.2    Hughes, C.E.3    Goodship, A.4    Caterson, B.5
  • 55
    • 13544258903 scopus 로고    scopus 로고
    • Cytokine induced metalloproteinase expression and activity does not correlate with focal susceptibility of articular cartilage to degeneration
    • Little C.B., Flannery C.R., Hughes C., Goodship A., Caterson B. Cytokine induced metalloproteinase expression and activity does not correlate with focal susceptibility of articular cartilage to degeneration. Osteoarthritis and Cartilage 2005, 13:162-170.
    • (2005) Osteoarthritis and Cartilage , vol.13 , pp. 162-170
    • Little, C.B.1    Flannery, C.R.2    Hughes, C.3    Goodship, A.4    Caterson, B.5
  • 56
    • 7944226150 scopus 로고    scopus 로고
    • Altered patterns and synthesis of extracellular matrix macromolecules in early osteoarthritis
    • Lorenzo P., Bayliss M.T., Heinegard D. Altered patterns and synthesis of extracellular matrix macromolecules in early osteoarthritis. Matrix Biology 2004, 6:381-391.
    • (2004) Matrix Biology , vol.6 , pp. 381-391
    • Lorenzo, P.1    Bayliss, M.T.2    Heinegard, D.3
  • 58
    • 36048985974 scopus 로고    scopus 로고
    • Double-knockout of ADAMTS-4 and ADAMTS-5 in mice results in physiologically normal animals and prevents the progression of osteoarthritis
    • Majumdar M.K., Askew R., Schelling S., Stedman N., Blanchet T., Hopkins B., Morris E.A., Glasson S.S. Double-knockout of ADAMTS-4 and ADAMTS-5 in mice results in physiologically normal animals and prevents the progression of osteoarthritis. Arthritis and Rheumatism 2007, 56:3670-3674.
    • (2007) Arthritis and Rheumatism , vol.56 , pp. 3670-3674
    • Majumdar, M.K.1    Askew, R.2    Schelling, S.3    Stedman, N.4    Blanchet, T.5    Hopkins, B.6    Morris, E.A.7    Glasson, S.S.8
  • 59
    • 0026352181 scopus 로고
    • Levels of serum keratan sulfate rise rapidly and remain elevated following anterior cruciate ligament transection in the dog
    • Manicourt D.H., Lenz M.E., Thonar E.J. Levels of serum keratan sulfate rise rapidly and remain elevated following anterior cruciate ligament transection in the dog. Journal of Rheumatology 1991, 18:1872-1876.
    • (1991) Journal of Rheumatology , vol.18 , pp. 1872-1876
    • Manicourt, D.H.1    Lenz, M.E.2    Thonar, E.J.3
  • 60
  • 61
    • 33744744388 scopus 로고    scopus 로고
    • Associations between joint space narrowing and molecular markers of collagen and proteoglycan turnover in patients with knee osteoarthritis
    • Mazzuca S.A., Poole A.R., Brandt K.D., Katz B.P., Lane K.A., Lobanok T. Associations between joint space narrowing and molecular markers of collagen and proteoglycan turnover in patients with knee osteoarthritis. Journal of Rheumatology 2006, 33:1147-1151.
    • (2006) Journal of Rheumatology , vol.33 , pp. 1147-1151
    • Mazzuca, S.A.1    Poole, A.R.2    Brandt, K.D.3    Katz, B.P.4    Lane, K.A.5    Lobanok, T.6
  • 62
    • 0017232897 scopus 로고
    • Biochemical changes in the cartilage of the knee in experimental and natural osteoarthritis in the dog
    • McDevitt C.A., Muir H. Biochemical changes in the cartilage of the knee in experimental and natural osteoarthritis in the dog. Journal of Bone and Joint Surgery 1976, 58:94-101.
    • (1976) Journal of Bone and Joint Surgery , vol.58 , pp. 94-101
    • McDevitt, C.A.1    Muir, H.2
  • 63
    • 0029154760 scopus 로고
    • Even low-grade synovitis significantly accelerates the clearance of protein from the canine knee. Implications for measurement of synovial fluid markers of osteoarthritis
    • Meyers S.L., Brandt K.D., Eilam O. Even low-grade synovitis significantly accelerates the clearance of protein from the canine knee. Implications for measurement of synovial fluid markers of osteoarthritis. Arthritis and Rheumatism 1995, 38:1085-1091.
    • (1995) Arthritis and Rheumatism , vol.38 , pp. 1085-1091
    • Meyers, S.L.1    Brandt, K.D.2    Eilam, O.3
  • 64
    • 0035095862 scopus 로고    scopus 로고
    • Measurement of cartilage oligomeric matrix protein (COMP) in normal and diseased equine synovial fluids
    • Misumi K., Vilim V., Clegg P.D., Thompson C.C., Carter S.D. Measurement of cartilage oligomeric matrix protein (COMP) in normal and diseased equine synovial fluids. Osteoarthritis and Cartilage 2001, 9:119-127.
    • (2001) Osteoarthritis and Cartilage , vol.9 , pp. 119-127
    • Misumi, K.1    Vilim, V.2    Clegg, P.D.3    Thompson, C.C.4    Carter, S.D.5
  • 66
    • 0036221754 scopus 로고    scopus 로고
    • Concentrations of cartilage oligomeric matrix protein in dogs with naturally developing and experimentally induced arthropathy
    • Misumi K., Vilim V., Carter S.D., Ichihashi K., Oka T., Sakamoto H. Concentrations of cartilage oligomeric matrix protein in dogs with naturally developing and experimentally induced arthropathy. American Journal of Veterinary Research 2002, 63:598-603.
    • (2002) American Journal of Veterinary Research , vol.63 , pp. 598-603
    • Misumi, K.1    Vilim, V.2    Carter, S.D.3    Ichihashi, K.4    Oka, T.5    Sakamoto, H.6
  • 67
    • 33749340005 scopus 로고    scopus 로고
    • Urine cartilage oligomeric matrix protein (COMP) measurement is useful in discriminating the osteoarthritic Thoroughbreds
    • Misumi K., Tagami M., Kamimura T., Miyakoshi D., Helal I.E., Arai K., Fujiki M. Urine cartilage oligomeric matrix protein (COMP) measurement is useful in discriminating the osteoarthritic Thoroughbreds. Osteoarthritis and Cartilage 2006, 14:1174-1180.
    • (2006) Osteoarthritis and Cartilage , vol.14 , pp. 1174-1180
    • Misumi, K.1    Tagami, M.2    Kamimura, T.3    Miyakoshi, D.4    Helal, I.E.5    Arai, K.6    Fujiki, M.7
  • 68
    • 0032456952 scopus 로고    scopus 로고
    • COMP (cartilage oligomeric matrix protein) is synthesized in ligament, tendon, meniscus, and articular cartilage
    • Müller G., Michel A., Altenburg E. COMP (cartilage oligomeric matrix protein) is synthesized in ligament, tendon, meniscus, and articular cartilage. Connective Tissue Research 1998, 39:233-244.
    • (1998) Connective Tissue Research , vol.39 , pp. 233-244
    • Müller, G.1    Michel, A.2    Altenburg, E.3
  • 69
    • 0027284796 scopus 로고
    • The link proteins. Review
    • Neame P.J., Barry F.P. The link proteins. Review. Experientia 1993, 49:393-402.
    • (1993) Experientia , vol.49 , pp. 393-402
    • Neame, P.J.1    Barry, F.P.2
  • 71
    • 50849101983 scopus 로고    scopus 로고
    • Evaluation of serum chondroitin sulfate and hyaluronan, biomarkers of osteoarthritis in canine hip dysplasia
    • Nganvongpanit K., Itthiarbha A., Ong-Chai S., Kongtawelert P. Evaluation of serum chondroitin sulfate and hyaluronan, biomarkers of osteoarthritis in canine hip dysplasia. Journal of Veterinary Science 2008, 9:317-325.
    • (2008) Journal of Veterinary Science , vol.9 , pp. 317-325
    • Nganvongpanit, K.1    Itthiarbha, A.2    Ong-Chai, S.3    Kongtawelert, P.4
  • 72
    • 0026499722 scopus 로고
    • COMP (cartilage oligomeric matrix protein) is structurally related to the thrombospondins
    • Oldberg A., Antonsson P., Lindblom K., Heinegård D. COMP (cartilage oligomeric matrix protein) is structurally related to the thrombospondins. Journal of Biological Chemistry 1992, 267:22346-22350.
    • (1992) Journal of Biological Chemistry , vol.267 , pp. 22346-22350
    • Oldberg, A.1    Antonsson, P.2    Lindblom, K.3    Heinegård, D.4
  • 73
    • 77649322497 scopus 로고    scopus 로고
    • A mouse model offers novel insights into the myopathy and tendinopathy often associated with pseudoachondroplasia and multiple epiphyseal dysplasia
    • Piróg K.A., Jaka O., Katakura Y., Meadows R.S., Kadler K.E., Boot-Handford R.P., Briggs M.D. A mouse model offers novel insights into the myopathy and tendinopathy often associated with pseudoachondroplasia and multiple epiphyseal dysplasia. Human Molecular Genetics 2010, 19:52-64.
    • (2010) Human Molecular Genetics , vol.19 , pp. 52-64
    • Piróg, K.A.1    Jaka, O.2    Katakura, Y.3    Meadows, R.S.4    Kadler, K.E.5    Boot-Handford, R.P.6    Briggs, M.D.7
  • 74
    • 0030750445 scopus 로고    scopus 로고
    • Chemical and immunological assay of the non-reducing terminal residues of chondroitin sulfate from human aggrecan
    • Plaas A.H.K., Wong-Palms S., Roughley P.J. Chemical and immunological assay of the non-reducing terminal residues of chondroitin sulfate from human aggrecan. Journal of Biological Chemistry 1997, 272:20603-20610.
    • (1997) Journal of Biological Chemistry , vol.272 , pp. 20603-20610
    • Plaas, A.H.K.1    Wong-Palms, S.2    Roughley, P.J.3
  • 75
    • 0002798430 scopus 로고    scopus 로고
    • Cartilage in health and disease
    • Lippincott, Williams and Wilkins, Philadelphia, PA, USA, W. Koopman (Ed.)
    • Poole A.R. Cartilage in health and disease. Arthritis and Allied Conditions. A Textbook of Rheumatology 2001, 226-284. Lippincott, Williams and Wilkins, Philadelphia, PA, USA. W. Koopman (Ed.).
    • (2001) Arthritis and Allied Conditions. A Textbook of Rheumatology , pp. 226-284
    • Poole, A.R.1
  • 76
    • 33744908602 scopus 로고    scopus 로고
    • Development and characterization of a highly specific and sensitive sandwich ELISA for detection of aggrecanase-generated aggrecan fragments
    • Prattay M.A., Su J.L., Leesnitzer M.A., Struglics A., Larsson S., Lohmander L.S., Kumar S. Development and characterization of a highly specific and sensitive sandwich ELISA for detection of aggrecanase-generated aggrecan fragments. Osteoarthritis and Cartilage 2006, 14:702-713.
    • (2006) Osteoarthritis and Cartilage , vol.14 , pp. 702-713
    • Prattay, M.A.1    Su, J.L.2    Leesnitzer, M.A.3    Struglics, A.4    Larsson, S.5    Lohmander, L.S.6    Kumar, S.7
  • 77
    • 0027322655 scopus 로고
    • Synovial fluid analyses detect and differentiate proetoglycan metabolism in canine experimental models of osteoarthritis and disuse atrophy
    • Ratcliffe A., Beauvais P.J., Fatemah S.-M. Synovial fluid analyses detect and differentiate proetoglycan metabolism in canine experimental models of osteoarthritis and disuse atrophy. Agents and Actions 1993, 39:63-67.
    • (1993) Agents and Actions , vol.39 , pp. 63-67
    • Ratcliffe, A.1    Beauvais, P.J.2    Fatemah, S.-M.3
  • 78
    • 0031934815 scopus 로고    scopus 로고
    • Regional differences in the rise in blood levels of antigenic keratan sulfate and hyaluronan after chymopapain induced knee joint injury
    • Rayan V., Thonar E.J., Chen L.M., Lenz M.E., Williams J.M. Regional differences in the rise in blood levels of antigenic keratan sulfate and hyaluronan after chymopapain induced knee joint injury. Journal of Rheumatology 1998, 25:521-526.
    • (1998) Journal of Rheumatology , vol.25 , pp. 521-526
    • Rayan, V.1    Thonar, E.J.2    Chen, L.M.3    Lenz, M.E.4    Williams, J.M.5
  • 79
    • 0031800304 scopus 로고    scopus 로고
    • Regulation of cartilage oligomeric matrix protein synthesis in human synovial cells and articular chondrocytes
    • Recklies A.D., Baillargeon L., White C. Regulation of cartilage oligomeric matrix protein synthesis in human synovial cells and articular chondrocytes. Arthritis and Rheumatism 1998, 41:997-1006.
    • (1998) Arthritis and Rheumatism , vol.41 , pp. 997-1006
    • Recklies, A.D.1    Baillargeon, L.2    White, C.3
  • 80
    • 33745620740 scopus 로고    scopus 로고
    • Link protein can retard the degradation of hyaluronan in proteoglycan aggregates
    • Rodriguez E., Roughley P. Link protein can retard the degradation of hyaluronan in proteoglycan aggregates. Osteoarthritis and Cartilage 2006, 14:823-829.
    • (2006) Osteoarthritis and Cartilage , vol.14 , pp. 823-829
    • Rodriguez, E.1    Roughley, P.2
  • 81
    • 0032493665 scopus 로고    scopus 로고
    • Cartilage oligomeric matrix protein shows high affinity zinc-dependent interaction with triple helical collagen
    • Rosenberg K., Olsson H., Mörgelin M., Heinegård D. Cartilage oligomeric matrix protein shows high affinity zinc-dependent interaction with triple helical collagen. Journal of Biological Chemistry 1998, 273:20397-20403.
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 20397-20403
    • Rosenberg, K.1    Olsson, H.2    Mörgelin, M.3    Heinegård, D.4
  • 82
    • 0030760574 scopus 로고    scopus 로고
    • Relations between synovial fluid and serum concentrations of osteocalcin and other markers of joint tissue turnover in the knee joint compared with peripheral blood
    • Salisbury C., Sharif M. Relations between synovial fluid and serum concentrations of osteocalcin and other markers of joint tissue turnover in the knee joint compared with peripheral blood. Annals of the Rheumatic Diseases 1997, 56:558-561.
    • (1997) Annals of the Rheumatic Diseases , vol.56 , pp. 558-561
    • Salisbury, C.1    Sharif, M.2
  • 83
    • 30544436016 scopus 로고    scopus 로고
    • Editorial: A contentious issue finds some clarity, on the independent and complementary roles of aggrecanase activity and MMP activity in human joint aggrecanolysis
    • Sandy J.D. Editorial: A contentious issue finds some clarity, on the independent and complementary roles of aggrecanase activity and MMP activity in human joint aggrecanolysis. Osteoarthritis and Cartilage 2006, 14:95-100.
    • (2006) Osteoarthritis and Cartilage , vol.14 , pp. 95-100
    • Sandy, J.D.1
  • 84
    • 0026660250 scopus 로고
    • Cartilage oligomeric matrix protein, a novel marker of cartilage turnover detectable in synovial fluid and blood
    • Saxne T., Heinegard D. Cartilage oligomeric matrix protein, a novel marker of cartilage turnover detectable in synovial fluid and blood. British Journal of Rheumatology 1992, 31:583-591.
    • (1992) British Journal of Rheumatology , vol.31 , pp. 583-591
    • Saxne, T.1    Heinegard, D.2
  • 85
    • 33646180025 scopus 로고    scopus 로고
    • Serum cartilage oligomeric matrix protein and other biomarker profiles in tibiofemoral and patellofemoral osteoarthritis of the knee
    • Sharif M., Granell R., Johansen J., Clarke S., Elson C., Kirwan J.R. Serum cartilage oligomeric matrix protein and other biomarker profiles in tibiofemoral and patellofemoral osteoarthritis of the knee. Rheumatology 2006, 45:522-526.
    • (2006) Rheumatology , vol.45 , pp. 522-526
    • Sharif, M.1    Granell, R.2    Johansen, J.3    Clarke, S.4    Elson, C.5    Kirwan, J.R.6
  • 87
    • 0028924415 scopus 로고
    • Monoclonal antibodies that detect biochemical markers of arthritis in humans
    • Slater R.R., Bayliss M.T., Lachiewicz P.F. Monoclonal antibodies that detect biochemical markers of arthritis in humans. Arthritis and Rheumatism 1995, 38:655-659.
    • (1995) Arthritis and Rheumatism , vol.38 , pp. 655-659
    • Slater, R.R.1    Bayliss, M.T.2    Lachiewicz, P.F.3
  • 88
    • 0033628325 scopus 로고    scopus 로고
    • Cartilage oligomeric matrix protein (COMP) levels in digital sheath synovial fluid and serum with tendon injury
    • Smith R.K., Heinegård D. Cartilage oligomeric matrix protein (COMP) levels in digital sheath synovial fluid and serum with tendon injury. Equine Veterinary Journal 2000, 32:52-58.
    • (2000) Equine Veterinary Journal , vol.32 , pp. 52-58
    • Smith, R.K.1    Heinegård, D.2
  • 89
    • 0025269111 scopus 로고
    • Identification of monoclonal antibodies that recognise novel epitopes in native chondroitin/dermatan sulfate glycosaminoglycan chains, their use in mapping functionally distinct domains of human skin
    • Sorrel J.M., Mahmoodian F., Schafer I.A., Davis B., Caterson B. Identification of monoclonal antibodies that recognise novel epitopes in native chondroitin/dermatan sulfate glycosaminoglycan chains, their use in mapping functionally distinct domains of human skin. Journal of Histochemistry and Cytochemistry 1990, 38:393-402.
    • (1990) Journal of Histochemistry and Cytochemistry , vol.38 , pp. 393-402
    • Sorrel, J.M.1    Mahmoodian, F.2    Schafer, I.A.3    Davis, B.4    Caterson, B.5
  • 91
    • 30544448357 scopus 로고    scopus 로고
    • Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase- and matrix metalloproteinase-generated aggrecan fragments
    • Struglics A., Larsson S., Pratta M.A., Kumar S., Lark M.W., Lohmander L.S. Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase- and matrix metalloproteinase-generated aggrecan fragments. Osteoarthritis and Cartilage 2006, 14:101-113.
    • (2006) Osteoarthritis and Cartilage , vol.14 , pp. 101-113
    • Struglics, A.1    Larsson, S.2    Pratta, M.A.3    Kumar, S.4    Lark, M.W.5    Lohmander, L.S.6
  • 92
    • 33751203834 scopus 로고    scopus 로고
    • Cartilage oligomeric matrix protein and hyaluronan levels in synovial fluid from horses with osteoarthritis of the tarsometatarsal joint compared to a control population
    • Taylor S.E., Weaver M.P., Pitsillides A.A., Wheeler B.T., Wheeler-Jones C.P., Shaw D.J., Smith R.K. Cartilage oligomeric matrix protein and hyaluronan levels in synovial fluid from horses with osteoarthritis of the tarsometatarsal joint compared to a control population. Equine Veterinary Journal 2006, 38:502-507.
    • (2006) Equine Veterinary Journal , vol.38 , pp. 502-507
    • Taylor, S.E.1    Weaver, M.P.2    Pitsillides, A.A.3    Wheeler, B.T.4    Wheeler-Jones, C.P.5    Shaw, D.J.6    Smith, R.K.7
  • 93
    • 0022339356 scopus 로고    scopus 로고
    • Quantification of keratan sulfate in blood as a marker of cartilage catabolism
    • Thonar E.J., Lenz M.E., Klintworth G.K. Quantification of keratan sulfate in blood as a marker of cartilage catabolism. Arthritis and Rheumatism 1997, 28:1367-1376.
    • (1997) Arthritis and Rheumatism , vol.28 , pp. 1367-1376
    • Thonar, E.J.1    Lenz, M.E.2    Klintworth, G.K.3
  • 94
    • 0033571757 scopus 로고    scopus 로고
    • Active matrix metalloproteinases are present in cartilage during immune complex-mediated arthritis, a pivotal role for stromelysin-1 in cartilage destruction
    • van Meurs J., van Lent P., Holthuysen A., Lambrou D., Bayne E., Singer I., van den Berg W. Active matrix metalloproteinases are present in cartilage during immune complex-mediated arthritis, a pivotal role for stromelysin-1 in cartilage destruction. Journal of Immunology 1999, 163:5633-5639.
    • (1999) Journal of Immunology , vol.163 , pp. 5633-5639
    • van Meurs, J.1    van Lent, P.2    Holthuysen, A.3    Lambrou, D.4    Bayne, E.5    Singer, I.6    van den Berg, W.7
  • 97
    • 0015582477 scopus 로고
    • The quantitative measurement of Alcian Blue-glycosaminoglycan complexes
    • Whiteman P. The quantitative measurement of Alcian Blue-glycosaminoglycan complexes. Biochemistry Journal 1973, 131:343-350.
    • (1973) Biochemistry Journal , vol.131 , pp. 343-350
    • Whiteman, P.1
  • 99
    • 34247479506 scopus 로고    scopus 로고
    • Selective and non-selective metalloproteinase inhibitors reduce IL-1-induced cartilage degradation and loss of mechanical properties
    • Wilson C.G., Palmer A.W., Zuo F., Eugui E., Wilson S., Mackenzie R., Sandy J.D., Levenston M.E. Selective and non-selective metalloproteinase inhibitors reduce IL-1-induced cartilage degradation and loss of mechanical properties. Matrix Biology 2006, 26:259-268.
    • (2006) Matrix Biology , vol.26 , pp. 259-268
    • Wilson, C.G.1    Palmer, A.W.2    Zuo, F.3    Eugui, E.4    Wilson, S.5    Mackenzie, R.6    Sandy, J.D.7    Levenston, M.E.8
  • 100
    • 0031791731 scopus 로고    scopus 로고
    • Identification of distinct metabolic pools of aggrecan and their relationship to type VI collagen in the chondrons of mature bovine articular cartilage explants
    • Winter G.M., Poole C.A., Ilic M.Z., Ross J.M., Robinson H.C., Handley C.J. Identification of distinct metabolic pools of aggrecan and their relationship to type VI collagen in the chondrons of mature bovine articular cartilage explants. Connective Tissue Research 1998, 37:277-293.
    • (1998) Connective Tissue Research , vol.37 , pp. 277-293
    • Winter, G.M.1    Poole, C.A.2    Ilic, M.Z.3    Ross, J.M.4    Robinson, H.C.5    Handley, C.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.