Effect of exercise on serum concentration of cartilage oligomeric matrix protein in thoroughbreds

American Journal of Veterinary Research

Volumn 68, Issue 2, 2007, Pages 134-140

  Helal, Ibrahim E ^a,c   Misumi, Kazuhiro ^a   Tateno, Oki ^b   Kodama, Takeshi ^b   Ishimaru, Matsuki ^b   Yamamoto, Junya ^b   Miyakoshi, Daiske ^a   Fujiki, Makoto ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b Japan Racing Association   (Japan)

^c Suez Canal University Faculty of Medicine   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

CARTILAGE OLIGOMERIC MATRIX PROTEIN; MONOCLONAL ANTIBODY;

ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXERCISE; FEMALE; HEART RATE; HORSE; MALE; NONHUMAN; PROTEIN BLOOD LEVEL; RUNNING; STANDARDIZATION; TRAINING; VELOCITY;

ANIMALS; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GENE EXPRESSION REGULATION; GLYCOPROTEINS; HORSE DISEASES; HORSES; JOINT DISEASES; MALE; PHYSICAL CONDITIONING, ANIMAL;

ANIMALIA; EQUIDAE;

EID: 33847668806     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.68.2.134     Document Type: Article

References (31)

1. Misumi K, Vilim V, Clegg PD, et al. Measurement of cartilage oligomeric matrix protein (COMP) in normal and diseased equine synovial fluids. Osteoarthritis Cartilage 2001;9:119-127.
2. Billinghurst RC. Biomarkers of joint disease. In: Robinson NE, ed. Current therapy in equine medicine. 5th ed. Philadelphia: WB Saunders Co, 2002;513-520.
3. Arai K, Misumi K, Carter SD, et al. Analysis of cartilage oligomeric matrix protein (COMP) degradation and synthesis in equine joint disease. Equine Vet J 2005;37:31-36.
4. Skioldebrand E, Lorenzo D, Zunino L, et al. Concentration of collagen, aggrecan and cartilage oligomeric matrix protein (COMP) in synovial fluid from equine middle carpal joint. Equine Vet J 2001;33:394-402.
5. Skioldebrand E, Heinegard D, Eloarnta M-L, et al. Enhanced concentration of COMP (cartilage oligomeric matrix protein) in osteochondral fractures from racing Thoroughbreds. J Orthop Res 2005;23:156-163.
6. van den Boom R, Brama PA, Kiers GH, et al. Assessment of the effects of age in the joint disease on hydroxyproline and glycosaminoglycan concentration in synovial fluid from metacarpophalangeal joint of horses. Am J Vet Res 2004;65: 296-302.
7. Fuller CJ, Barr AR, Sharif M, et al. Cross-sectional comparison of synovial fluid biochemical markers in equine osteoarthritis and the correlation of these markers with articular cartilage damage. Osteoarthritis Cartilage 2001;9:49-55.
8. Smith RKW, Zunino L, Webbon PM, et al. The distribution of cartilage oligomeric matrix protein (COMP) in tendon and its variation with tendon site, age and load. Matrix Biol 1997;16:255-271.
9. Smith RKW, Heinegård D. Cartilage oligomeric matrix protein (COMP) levels in digital sheath synovial fluid and serum with tendon injury Equine Vet J 2000;28:52-56.
10. Misumi K, Tagami M, Kamimura T, et al. Urine cartilage oligomeric matrix protein (COMP) measurement is useful in discriminating the osteoarthritic Thoroughbreds. Osteoarthritis Cartilage 2006;14:1174-1180.
11. Misumi K, Vilim V, Hatazoe T, et al. Serum level of cartilage oligomeric matrix protein (COMP) in equine osteoarthritis. Equine Vet J 2002;34:602-608.
12. Neidhart M, Muller-Ladner U, Frey W, et al. Increased serum levels of non-collagenous matrix proteins (cartilage oligomeric matrix protein and melanoma inhibitory activity) in marathon runners. Osteoarthritis Cartilage 2000;8:222-229.
13. van de Lest CH, van den Hoogen BM, van Weeren PR. Loading-induced changes in synovial fluid affect cartilage metabolism. Biorheology 2000;37:45-55.
14. Piscoya JL, Fermor B, Kraus VB, et al. The influence of mechanical compression on the induction of osteoarthritis-related biomarkers in articular cartilage explants. Osteoarthritis Cartilage 2005;13:1092-1099.
15. Blain EJ, Gilbert SJ, Wardale RJ, et al. Up-regulation of matrix metalloproteinase expression and activation following cyclical compressive loading of articular cartilage in vitro. Arch Biochem Biophys 2001;396:49-55.
16. McDonald JN, Levick JR. Effect of extravascular plasma protein on pressure-flow relations across synovium in anaesthetized rabbits. J Physiol 1993;465:539-559.
17. McDonald JN, Levick JR. Effect of intra-articular hyaluronan on pressure-flow relation across synovium in anaesthetized rabbits. J Physiol 1995;485:179-193.
18. 99mTc-DTPA clearance from knee with effusions. J Rheumatol 1994;21:501-504.
19. Gaffney K, Williams RB, Jolliffe VA, et al. Intra-articular pressure changes in rheumatoid and normal peripheral joints. Ann Rheum Dis 1995;54:670-673.
20. Okumura M, Kim GH, Tagami M, et al. Serum keratan sulphate as a cartilage metabolic marker in horses: the effect of exercise. J Vet Med A Physiol Pathol Clin Med 2002:49;195-197.
21. Mundermann A, Dyrby CO, Andriacchi TP, et al. Serum concentration of cartilage oligomeric matrix protein (COMP) is sensitive to physiological cyclic loading in healthy adults. Osteoarthritis Cartilage 2005;13:34-38.
22. Kersting UG, Stubendorff JJ, Schmidt MC, et al. Changes in knee cartilage volume and serum COMP concentration after running exercise. Osteoarthritis Cartilage 2005;13:925-934.
23. Pap G, Eberhardt R, Sturmer I, et al. Development of osteoarthritis in the knee joints of Wistar rats after strenuous running exercise in a running wheel by intracranial self-stimulation. Pathol Res Pract 1998;194:41-47.
24. Lin PM, Chen CT, Torzilli PA. Increased stromelysin-1 (MMP-3), proteoglycan degradation (3B3- and 7D4) and collagen damage in cyclically load-injured articular cartilage. Osteoarthritis Cartilage 2004;12:485-496.
25. Brama PA, van den Boom R, DeGroott J, et al. Collagenase-1 (MMP-1) activity in equine synovial fluid: influence of age, joint pathology, exercise and repeated arthrocentesis. Equine Vet J 2004;36:34-40.
26. van den Boom R, Brama PA, Kiers GH, et al. The influence of repeated arthrocentesis and exercise on matrix metalloproteinase and tumour necrosis factor alpha activities in normal equine joints. Equine Vet J 2004;36:155-159.
27. Engstrom-Laurent A, Hallgren, R. Circulating hyaluronic acid levels vary with physical activity in healthy subjects and in rheumatoid arthritis patients. Relationship to synovitis mass and morning stiffness. Arthritis Rheum 1987;30:1333-1338.
28. Simkin PA, Huang A, Benedict RS. Effects of exercise on blood flow to canine articular tissues. J Orthop Res 1991;8:297-303.
29. Edmonds S, Turnbull C, Blake D. Effect of intensive exercise on patients with active RA. Ann Rheum Dis 2001;60:429.
30. Kuroki K, Cook JL, Stoker AM, et al. Characterizing osteochondrosis in the dog: potential roles for matrix metalloproteinases and mechanical load in pathogenesis and disease progression. Osteoarthritis Cartilage 2005;13:225-234.
31. Murray RC, Smith RK, Henson FM, et al. The distribution of cartilage oligomeric matrix protein (COMP) in equine carpal articular cartilage and its variation with exercise and cartilage deterioration. Vet J 2001;162:121-128.